lig4 (lig4,LOC108412030,LOC107654268)


Basic Information

Item Value
gene id lig4
gene name lig4,LOC108412030,LOC107654268
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047620.1
NCBI id CM018566.1
chromosome length 19313417
location 8006372 ~ 8010233 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026932396.2
TTAGTGGccagtttatattttatctttcaaaataaacattcaGTAACTatccaaaatcacaaaaatatattagattgtatttattttttaaaatcatcaaGTCAAATGTGCGCTAATTCTTTATAAACTACAGCGTCCGGAGAACTGTTTACTGTCGGCTTCCATAGCAACCCGGAAAAGCTGTTCATAAACAAGGAAATGTAGGGCAAGTTCAGACATCAGCCCTGTAACATCTGGCCAGTTCTTCTTCGTGCAAACGCAGacatcatcaacatcatcaatgGACGGCTCATCCAAAGGCAAGACAGCAGAGGAAACATCCAAAAGTGACGCTGCATCTAAAACATCTGTGGCTGCGCAAGTGCCATTTCTTGACCTGTGCACTGTTCTCGAGAATATCCAGAAAGCCAAACATCGGCCAGACAAGTCCAAATGCTTAAAGGATTTCATAGATTCATGGAGAAGGTTTCATGCAGCTCTTCACAAAGATAATCCCGACACTACAGATTCATTTTACCCAGCCATGCGTCTTATTGTGCCTCCTTTTGAAAGGGAGAGAATGGCCTATGGTATCAAAGAAAACATGTTAGCCAAACTCTACATTGAGGTCTTAGGTCTTCCAAAATCAGGGCCAGAGGCTAATAAACTTCTCAATTACAGAGCCCCTACTACATCCAAAGGAGACTCTGGAGACTTTGCTCTTACAGCTTATTTTGTCCTCAAAAAGAGATGCACAAGCCGGGGTAATCTGAGTATCAAAGAGGTCAATGACTTCTTGGACTCAGTAGCTATGAATAACGCCAGCAAACAGAAGGACCTTGTGAAGAAAAGCCTTTTACATTTGATTACTCAAAGCTCAGCTTTGGAACAGAAGTGGCTTATTCGTATGATCCTGAAAGACATGAAACTTGGGATTAGCAAGGAGACCGTTCTCCAGGTTTTTCACTCAGATGCTCCAGAGCTCTACAATGTCACTACAGCCTTGGACAGGGTCTGCAGACAGCTACATGACCCCTCTATTTCCTTGAATGAGGTATCCATCGGCCTGTTTTCTGCCTTCAAACCCATGCTGGCGGCTATCGCCAACATCCGCCAAGTGGAGAAACAGATGGGGAATCAGCCCTTCTATATTGAGACCAAGCTGGATGGTGAGCGCATTCAACTTCATAAGGATGGGGATGTATACAAATACTACAGCCGTAACTCATTTGAATACACACAACAGTTCGGGGCCTCACCACTAGAGGGTTCTCTCACACCATTCATCCACAATGTCTTTAAATCTCATGTTGTCAATTGTATCttggatggagagatgatggCTTATAACCCCACCACAGAGACTTTCATGCAAAAAGGCAGCAAATTTGATATCAAGCGGTTGGTGGAGGACTCTGATTTACAGAcatgcttttgtgtgtttgatgtcCTGCTTGTCAATGACCAGAAGTTTGGAAATGAGCCTCTCAAGAAGCGTTACGACACTCTCCAGACAGTCTTCACACCCGTCAAAGGCCGGAtccagctggtacagtacactgAAGCCAAAACCAGGCAGGAAGTGATAAATGCCCTTAATGAAGCTATTGACAACCGTGAAGAAGGCATCATGGTCAAAGACCCCTTGTCCATCTACAAGCCAGATAAACGTGGTGAAGGCTGGCTGAAGATCAAACCTGAATATGTTGATGGCCTGATGGATGAATTGGATTTGCTAATAGTGGGAGGCTATTGGGGGAAAGGCAGACGGAGTGGAATGTTGTCCCACTTTCTCTGTGCTGTTGCTGAAACTCCAAGTCCTGGAGAGAAGCCAACAGTGTTCCATACACTCTGTCGAATTGGATCAGGCTACACCATGAAGGAGCTCTATGAGCTTGGCCTGAAACTGGCCGAACACTGGAAAGTTTATCGCAAGAGTAGTCCTCCGGCAGGCATTTTGTGTGGAACAGAGAAGCCGGAGGTTTACATTGAGCCAAGAAACTCAGTGATCATTCAAGTCAAAGCGGCAGAGATTGTTACCAGTGACATGTACAAAACTAATTGCACTCTGCGATTCCCCAGGATTGAGAGGATCCGAGAGGACAAAGAATGGTATGAGTGCATGACCTTGGATGAGATAAGTCAGTTCCGTGATAAAGCATCGGGTAAACTGGCATCCAGGCACCTTCACCTCCAGGAAGACGAGCCGGAGAAGAAGAAACGCAAGCTCGCATCCAAGCCCAAAAAGACCATTGGCATTGTTGACCACTTCAAATCTCAAGACCTGTCCACTGTCACCAAAGAGACAGACATGTTTGAAGATGTGGAATTCTGTGTGATGAGCGGAAGTAATACGCATTCAAAGGCCGAGCTTGAAAAGGCTGTGGCCCGTGGCGGAGGCATTGTAGTCCAGAACCCTGGAAAGGACACGTACTGTGTGATTGCAGGTGTTGAGAACGTGCGGGTAAAGAACCTCATTGGTTCAAACCAACATGACGTAGTATGGGCTTCCTGGCTCCTGGAATGTCTGGACAGGAAACAGGTGCTACCATGGCAACCACGACACATGATCCACATGTCCCCTTCCACAAGGGAACACTTTGCTGAAGAGTATGATTGCTATGGAGACAGTTACTACGTCGACACAGATGAGCAGCAGCTGAGGGATGTCTTCAGCAGAATGGAGCCTGTTGAAGTGGATGCAGTATCCATAGCTTCAATCGAGCAGAAGTACGGCTTTGATGACTTGCCCACTAGCATGTTCAGACCTTACCGTGCCTACTTTGACCGATGTGCTGATTTGGGCAATCCAGAAAGTCTTATTAAGGGTACATGTCTGAACTTTCGGGCTCTTGAGTTTCGCTTTCATGGGGGCACAGTAGTAGAAAGACTAGAAGAAGGCATCACACATGTAGTCATGGCAGGGGAAGAGAGATTATTGGACATAAGGACACATAGACGCCTCTTTACTAAGAAGTTTAAGATCGTTCGAGAAACATGGGTGACTGATTCTATTAAAGCAGGACACGTACTTAATGACAATGATTACCTTGTGTAATTTGGAGACAGCTACGCAATGTCACATATCACTTAAAGACTGCGTTGTCTCCGAATAATCTTTGTCCTAGCcattattaatgctaaaatgATGTCTGGATCTGGTTGTGTTTCTACTTTGACTgtgaacatttttaatgaatagaaAAATCATTGTGTAGCTTTGTATTTTAACTATAGGCTTATTATTTAACAATTGCAGGTTTTAGataatgctgtttttttagACAAATATGTTCTCGTGTAGTCAAGTCTCTGTTTGCTTGCTTACAGAGAACAACACTAGGAtgacaaagacattttatttgctTCCTACAGATTGTATGAAAGAATAACAAGGAATAAACCTGTTTTTAATCTATAactataaaattgtaattattgtttgaataaagatataaagaataaagaga

Function

symbol description
lig4 Predicted to enable ATP binding activity; DNA binding activity; and DNA ligase (ATP) activity. Acts upstream of or within double-strand break repair via nonhomologous end joining. Predicted to be part of DNA ligase IV complex and DNA-dependent protein kinase-DNA ligase 4 complex. Human ortholog(s) of this gene implicated in several diseases, including DNA ligase IV deficiency; colorectal cancer; high grade glioma; multiple myeloma; and prostate cancer. Orthologous to human LIG4 (DNA ligase 4).

NR:

description
PREDICTED: DNA ligase 4

GO:

id name namespace
GO:0006303 double-strand break repair via nonhomologous end joining biological_process
GO:0006310 DNA recombination biological_process
GO:0006260 DNA replication biological_process
GO:0051103 DNA ligation involved in DNA repair biological_process
GO:0003910 DNA ligase (ATP) activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0003677 DNA binding molecular_function

KEGG:

id description
K10777 LIG4, DNL4; DNA ligase 4

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026932396.2 True 3449 mRNA 0.43 2 8006372 8010233

Neighbor

gene id symbol gene type direction distance location
mid1 mid1,LOC103030906,LOC106575281,LOC106574413 coding downstream 703808 7253751 ~ 7302564 (-)
ednrba ednrb,LOC108258323,LOC108434743,LOC107658690,LOC107566659,LOC105911940,LOC106600156,LOC105022329 coding downstream 779723 7218365 ~ 7226649 (-)
LOC113537349 LOC108258693 coding downstream 805047 7184802 ~ 7201325 (-)
sugt1 sugt1,LOC104941757 coding downstream 824890 7156580 ~ 7181482 (-)
pcdh8 LOC108258318 coding downstream 909666 7092802 ~ 7096706 (-)
irs2a LOC108258957,LOC108434672 coding upstream 32252 8042485 ~ 8054545 (-)
LOC113537312 LOC108259043 coding upstream 51988 8062221 ~ 8066451 (-)
LOC113537306 ube2a,ube2al,LOC108259060,LOC103029486,LOC103021436,LOC107552373,LOC105934920,LOC107588833 coding upstream 77547 8087780 ~ 8090097 (-)
ankrd10a ankrd10 coding upstream 81133 8091366 ~ 8105352 (-)
cryaa cryaa,LOC106939151 coding upstream 117328 8127561 ~ 8131183 (-)
G372300 NA non-coding downstream 17174 7988950 ~ 7989198 (-)
G372288 NA non-coding downstream 29381 7976777 ~ 7976991 (-)
G372168 NA non-coding downstream 96820 7909124 ~ 7909552 (-)
G372132 NA non-coding downstream 225167 7780062 ~ 7781205 (-)
G372085 NA non-coding downstream 275264 7730710 ~ 7731108 (-)
G372307 NA non-coding upstream 5872 8016105 ~ 8016388 (-)
G372471 NA non-coding upstream 192535 8202768 ~ 8204224 (-)
G372522 NA non-coding upstream 418371 8428604 ~ 8444065 (-)
G372742 NA non-coding upstream 764799 8775032 ~ 8788141 (-)
LOC113537261 NA non-coding upstream 953352 8963585 ~ 8965621 (-)
fam155a LOC108258331 other downstream 13276 7912210 ~ 7993096 (-)
G372086 LOC108258915 other downstream 281577 7718263 ~ 7724795 (-)
LOC113537388 arhgap6 other downstream 527863 7357271 ~ 7478509 (-)
LOC113537271 LOC108258282 other downstream 937841 7058835 ~ 7068531 (-)
pspc1 pspc1,LOC108258933,LOC108434730 other downstream 1095826 6870566 ~ 6910546 (-)
cars2 cars2 other upstream 59169 8069402 ~ 8084539 (-)
LOC113537489 NA other upstream 251202 8261435 ~ 8267272 (-)
timmdc1 timmdc1 other upstream 310635 8320868 ~ 8329026 (-)
LOC113537606 nhlh2,LOC108258389,LOC103035065,LOC108434665,LOC107739819,LOC105019883 other upstream 419329 8429562 ~ 8432438 (-)
tsga10 LOC108258346 other upstream 581174 8591407 ~ 8610841 (-)

Expression


Co-expression Network