AMCG00000085 (nkx2.1,nkx2-1,LOC107679765,LOC107666245,LOC107582966,LOC107578306)


Basic Information

Item Value
gene id AMCG00000085
gene name nkx2.1,nkx2-1,LOC107679765,LOC107666245,LOC107582966,LOC107578306
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030141.1
NCBI id CM030141.1
chromosome length 22147039
location 2858153 ~ 2860184 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00000085
ATGTCGATGAGTCCCAAGCATACGACTCCTTTCTCTGTTTCCGATATCTTGAGTCCCCTTGAGGAGAGCTACAAGAAAGTGAGTATGGAGGGCAACAACTTGGGGGCTCCCCTGACAGCCTACCGACAGCCCCAGGTCTCTCAGGCGGCTATGCAGCAGCACCACATGGGGCACAACGGCACGGTGCCCGCTACTTACCACATGGCTGCCGCTGGGGTGCCTCAGCTCTCTCACTCGGCCATGGGGGGCTACTGCAACGGGAACCTGGGCAACATGAGCGAGCTTCCGCCTTACCAGGACACCATGAGGAACAGCAGCTCGGCCACCGGGTGGTATGGAGCCAATCCGGATCCGCGCTTCTCCTCAATCTCTCGCTTTATGGGATCATCCTCTGGAATGAACATGGGCGGCATGGGCAGTCTGGGTTCTCTGGCAGACGTGGGGAAGAGTATGGGTCCCTTGCAGAGCACCCCAAGGAGAAAACGAAGGGTGCTCTTCTCTCAGGCGCAGGTTTACGAGTTAGAAAGACGGTTCAAGCAACAGAAATACCTCTCGGCCCCGGAAAGGGAACATTTGGCCAGCATGATCCACCTCACTCCGACTCAGGTTAAAATCTGGTTCCAGAACCACCGGTACAAGATGAAACGGCAGGCCAAAGACAAGGTGACCCAGCAGCAGATGCAACAGGACTCCAGCTCCTgtcagcaacagcagcaatcCCCCAGAAGAGTAGCCGTGCCAGTGTTAGTAAAGGACGGCAAGCCTTGCCAAGGAGGCGCAAATACGCCGACCACTGCCATCCAGAACCACCACCAGCAAGCGAGTAACGTTATGACGGTGTCCACTAATAATACTGGCATGGGTCAACATCAGAGCCAACAGGCGAGCAGTGCAGGCCACTCTCCAGATTTGGGTCACTCAAGCAGCCCCTCGTCACTTCAAAGCCAGGTGTCTagtctctctcacctgaactcTGCCAGCTCCGAGTACGGCAACGCCATGCCCTGCTCTGCGCTATTATATGGCAGGACCTGGTGA

Function

symbol description
nkx2.1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within hypothalamus development. Predicted to be active in nucleus. Is expressed in brain; head; swim bladder; and thyroid follicle. Human ortholog(s) of this gene implicated in choreatic disease and thyroid gland papillary carcinoma. Orthologous to human NKX2-1 (NK2 homeobox 1).
nkx2-1 Enables several functions, including DNA-binding transcription factor activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including animal organ development; negative regulation of transforming growth factor beta receptor signaling pathway; and positive regulation of macromolecule metabolic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Implicated in choreatic disease and thyroid gland papillary carcinoma.

NR:

description
NK2 homeobox 1b

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K09342 NKX2-1, TITF1; homeobox protein Nkx-2.1

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00000085 True 1038 mRNA 0.56 2 2858153 2860184

Neighbor

gene id symbol gene type direction distance location
AMCG00000088 NA coding upstream 17118 2839915 ~ 2841035 (+)
AMCG00000086 slc25a21,LOC107679800 coding upstream 67666 2776667 ~ 2790487 (+)
AMCG00000074 LOC106602716,LOC107752725 coding upstream 250162 2572779 ~ 2607991 (+)
AMCG00000071 NA coding upstream 722255 2128584 ~ 2135898 (+)
AMCG00000070 tmem229b,LOC107752730,LOC107708331,LOC102785226 coding upstream 742986 2114661 ~ 2115167 (+)
AMCG00000075 NA coding downstream 216001 3076185 ~ 3107875 (+)
AMCG00000078 NA coding downstream 543175 3403359 ~ 3416557 (+)
AMCG00000079 NA coding downstream 583329 3443513 ~ 3464306 (+)
AMCG00000081 NA coding downstream 604179 3464363 ~ 3469964 (+)
AMCG00000082 adssl1,pura1 coding downstream 663416 3523600 ~ 3536734 (+)
G147739 NA non-coding upstream 332732 2525191 ~ 2525421 (+)
G147735 NA non-coding upstream 379195 2478710 ~ 2478958 (+)
G147689 LOC107575789 non-coding upstream 489708 2301487 ~ 2368445 (+)
G147688 NA non-coding upstream 500016 2291140 ~ 2358137 (+)
G147806 NA non-coding downstream 149899 3010083 ~ 3016145 (+)
G147807 NA non-coding downstream 160211 3020395 ~ 3021571 (+)
G147808 NA non-coding downstream 162754 3022938 ~ 3023268 (+)
G147809 NA non-coding downstream 165194 3025378 ~ 3025789 (+)
G147814 NA non-coding downstream 174835 3035019 ~ 3036346 (+)
G147726 LOC104962440 other upstream 454181 2403730 ~ 2403972 (+)
AMCG00000073 mta1,LOC107679789,LOC107666257,LOC107600838 other upstream 799383 2036023 ~ 2058770 (+)
G147416 NA other upstream 1741203 1063085 ~ 1116950 (+)
G147311 NA other upstream 2359642 449652 ~ 498511 (+)
AMCG00000032 NA other upstream 2603712 231336 ~ 254441 (+)
AMCG00000094 NA other downstream 830588 3690772 ~ 3699093 (+)
AMCG00000093 srp14,LOC106610862 other downstream 860801 3720985 ~ 3724316 (+)
G148040 NA other downstream 899995 3760179 ~ 3760624 (+)
AMCG00000113 NA other downstream 1251936 4112120 ~ 4193033 (+)
AMCG00000136 btbd7 other downstream 2228255 5088439 ~ 5161195 (+)

Expression


Co-expression Network