AMCG00000257 (gch1)



Basic Information


Item Value
gene id AMCG00000257
gene name gch1
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information


Item Value
chromosome id CM030141.1
NCBI id CM030141.1
chromosome length 22147039
location 8946663 ~ 8961375 (-)
genome version AmiCal1_2021_bowfin_Genome

Sequence


>AMCG00000257
CTGACAGCCAGTGACGCACTACCTGAGCGGCCAATGGCGGCCCGGTGGGATCAGCCCGTGTGTATAAAAGCACAGGGAAACAACGTGCTTTATTTCACTTACCAACACAGCGCAGGGGAGCCGTCCCTCGCCAGGAGTTCAGCCAAGACCGGCAAAAGAGAGCAAGAAACAAAGTGACAGATACCGTCTCTGTTCACCATCTCCCTCGTCATACAGTGAGAGAAGAGTGAAGCCGGTTTTCAACTTCAAGCAATGGAGCGGGTCAAGCAACTGCCCGAGAAGCAAGTGACCCGCGATATGAATGGGCACCTGGAGGGGAGGACGGCCGACAATGCGTCCCCCCGACGGGTCCCCGGCGAGAGCAGCTCCGGCGGGGACGGCTGGAGAGACGAGCGGCCGCGCAGCGTCGAAGACAACGAGGTGAGCTTGCCCAGCCTGGCCACTGCCTACAGCACCATCCTCCGGGGCCTGGGAGAAAACCCCGACAGACAGGGGCTCCTCAAGACGCCCTGGAGAGCCGCCAAGGCCATGCAGTTCTTCACCAAGGGCTACCAGGAGAGCATCACAGaTGTGTTGAATGATGCGATTTTTGATGAGGACCATGACGAGATGGTGATCGTGAAGGACATCGACATGTTCTCCATGTGTGAGCACCACCTTGTCCCATTCATTGGCAAGGTACACATAGGCTACCTCCCCAACAAGAGAGTGCTGGGCCTCAGCAAACTGGCCAGaaTCGTTGAAATTTATAGCAGACGACTACAAgTTCAGGAGCGCTTGACCAAGCAGATTGCTGTTGCCATCACTGAAGCTTTGCAGCCCTGCGGGGTGGGCGTCGTCATCGAGGCCACTCACATGTGCATGGTCATGAGAGGGGTCCAGAAGATGAACAGTAAGACTGTGACCAGCACCATGCTGGGTTTTTTTCGTGAAGACCCCAAGACCAGGGAGGAGTTTCTCACCCTCATACGGAGCTGAGTCGTTGCGGTGCACCTGCCAAATCTTTCCCCTCGATTCGCAACTGCCCTGCCAGACCCTATCCCCAGGAAATGCCAGAGAGGAGTTCCTGTCGCTGAAAGAGTCCTGAGCCACGACTCGCCTGAGCCAGACCACAGTCTCCCTTTCAATGGACTGGCCGAAAAGACACTTTCCTCTTCTTGGCACCTTCCTTAGTTTCTTAGTTCTGCATTTTGCTTCTTCAAGGTTATATGGTGATCTTGTGCAAACTAGTTCAATCTGGGATAGACTGGTCAGCCCTTGAGTGGATGTAAAGACTTAGTTTGGCTGTCATGTTCTCCAATGCAATGGTTGTGTAATTAACCCTTTCTTTCCCCAATGTTTGAACCATGGACAGGTGAAAAGTCACAGGTGAGGGGCGGGGCACTTGCGAACTGTCGACTGGGGGGGGTTCTGACGATTTGTTGACTGGGGGTGCACTACGGGAGGGCACTTTCTGGGTGGCAGGGGCCGTCGCCCCTTTCGCCCCCACATGCCTGCCGGTGAGGCTGTAGTGTACTCCATTTAACAGAGCAGTGCAGGGTTCTTCAGagcttttaatgatttataaagcTTCAGAAATTAATCACTGATGCcttttaaactatatatttggtatgtgattttgtttttttttgtttttgttttgctccatAATTGAAGAGACTGAAATATAAAGATTAGAtgctagtttaaaaaaaaaatagtattaaaCTTAATTAACTGGATGGTGTGGTCTGTACACAGATATGCCTCTTCTAACAAGGCTGAACCAGTGTAACCCTTTACACTCGGACCCATTTTCGCCTGGTTGAACTTCTTAGACGcatgtttaatatggacattataaggagtacaAGTATGTgcctatcaaatgaaactagacaacctgtactataatctgcatagttgatcatgattagacaaaatATTACTGTActaccatgttttttttttttttaattgaccttTAACCTGTTGACCCATTAAAATCTATGGGAAAtctctttttttgttatgttgaAATGCCACTCAAATTTGAAATTTGTAGAAGTTATTTGGTGTAAATCGCATaagaaattaaggaataatgtgcattttcaaattacaaatttcCCTTAAAGTACTAGTCAAAATGCAACTTGAGACGCACTGGGTGAAAATGGGATACAAATTGAAGGAGTtatggtaatttatttttcatgtattcaaATGGCAGTTCTCAATTTTTCCCACTAATTTGCAAGTGAATATCTCCACACAGCAACATTGGATCTTAACAATCTTGGTATCATTTGAAAGCCCCAAGACTCTAGTTTATCTGGCTATAATAGTGTCATagttattcatatatttccGCACACTGGCAGGTTTAAAACAATGGGGCTGAGTGTAATGGGTTAAAACCATTTATGACAATGTGGGTGGAGGTAGTTAACCCCTTAACTGTACACTAATCTAAACCCTGATTACCAAACTACACATTCCAGGACACTCGTGATTTGCACATTTCACAGGTGGAATCCTTACAGATCACTGTAAATGTGGGCAGTTTTTATTGCCAAAACAATACGAATTTTACCTTTTtcaatgttgaaaatgttatttataaaagtGTAAACAATGTATGGTACTTTAggtttcagtgttttacaggCAGTGTTTcttgtgatgtttttgttgaTGACTTGCAAAGCACTTTGGGTATTAAAACCGTAAGAATTTTGCCTGTGGTTTGATCCAGCATTATTAAAATCTGTTGGGTTTGTTATTCATCTTGAACAACATTAGTCAGGTTAACTCGTCTCATTTTAATCTAGTGTTAACGCATTCAGATGCACCCGTCTCTGCTATGATCTTTGTGTCGTTTCATGTCATGTTTCGGAATGAAGGAAATGATTTGCattcaaaactaattttaattctAAATTCTTTAATTTTCTGCTTGTCCAAGTGTTTTACATGTGTGTGATTATGGAGAAAGTTAACCGCCAGCAGTCAATACTGCTATTCAGACAAGAATGGGgagatttaatttccatttgttctaAAATGTCTAGTTTGTAATCACATAGCTGCTATAAAAATGAACCCGGACTGCATAAACCAGAGTGCCCATAGTgctgaaagtgtttttattgttgcttAATGTATGACATGTTGTTCAATGTCTTTTTGATATGAACTTTTACTTTTCAGTCGTTACAAATTCTAAGTggataaaacatgtattttaccaTTTGAACTATTGTATGAATTGTTACGATCATGTCTGGAGGTGTCCATACTGTGTTGTCTGAGCAAGATTTTAATCTTAGTCCTGTACCTTAGAACCAGACTGTAGCAGTTTGTTCCGGGGCGCTTTTCTCACCTGGGCCCTTGTCTTTTTCTGTATGTGAACATGTATGGTCCCCCTCTTCTCTAGATTTTTGTACAACTTTCAGGGCATTGATGCATCTTTTTCATGTAGATTGATATGAAGATaactttatttaatatgtacagtgtatactgaattttaattttatagtaATTTACTTGGGACCCCGCTGTGGTCGAATCGGAGATTGCTCACCcttcattttatctttttagtttttagcaTGCAGGAGAACCCACTAAAAATATCTGCAATGATGTCAGAGTGGAGAAGGGGTAGAGACTGGTTTAAGTGGAGATTTTGTGGCCTTGTCTTGGAGGGATTTAGAGGACTGGGCCATAAGAGCCTGTATCTATCCCTCTGTGTTCACACTGTGGGGGAAATCATCCTTTTGAATTACATGATTTTTAGgatgttttaagaaatgtgtacatataaataaatattgtacaatGTTTTATGTGTAGGATTATAATTAATGCTTAGTAATTTGTTTCTCAAATATTGAACTGCATAATTGAACCCATGACTCAATTCAGGTAAGCCATATCACAATTGGTTCCCGTATCACCGCAAGAAATAGTGGATTCATGTTTTAGTTCAATTTATTAACTGCTCAAAGGTATATACAAGTAGATGGAGGCGTTTCGGCCAAGAccgg

Function


symbol description
gch1 Predicted to enable GTP binding activity; GTP cyclohydrolase I activity; and zinc ion binding activity. Predicted to be involved in tetrahydrobiopterin biosynthetic process. Predicted to act upstream of or within tetrahydrofolate biosynthetic process. Predicted to be active in cytoplasm. Is expressed in brain; dopaminergic neurons; trunk; and xanthophore. Human ortholog(s) of this gene implicated in BH4-deficient hyperphenylalaninemia B; bipolar disorder; dystonia; and dystonia 5. Orthologous to human GCH1 (GTP cyclohydrolase 1).

NR:

description
PREDICTED: GTP cyclohydrolase 1

GO: NA

KEGG:

id description
K01495 GCH1, folE; GTP cyclohydrolase IA

RNA


RNA id representative length rna type GC content exon number start site end site
AMCG00000257 True 4037 mRNA 0.42 6 8946663 8961375

Neighbor


gene id symbol gene type direction distance location
AMCG00000241 bmp4 coding downstream 82712 8853219 ~ 8863951 (-)
AMCG00000243 NA coding downstream 131747 8788105 ~ 8814916 (-)
AMCG00000242 fermt2 coding downstream 175447 8751677 ~ 8771216 (-)
AMCG00000254 NA coding downstream 212115 8729285 ~ 8734548 (-)
AMCG00000253 stxbp6 coding downstream 259580 8668901 ~ 8687083 (-)
AMCG00000265 NA coding upstream 1593 8962968 ~ 8977588 (-)
AMCG00000262 NA coding upstream 16249 8977624 ~ 8984923 (-)
AMCG00000264 NA coding upstream 26940 8988315 ~ 8989445 (-)
AMCG00000261 styx,LOC107680756,LOC107723651,LOC106602923 coding upstream 43156 9004531 ~ 9009477 (-)
AMCG00000263 psmc6,prs10,LOC107668141,LOC107582103,LOC107549540 coding upstream 49820 9011195 ~ 9017940 (-)
G149132 NA non-coding downstream 1075 8882648 ~ 8945588 (-)
G149125 NA non-coding downstream 94884 8851316 ~ 8851779 (-)
G149087 NA non-coding downstream 202164 8743871 ~ 8744499 (-)
G149077 stxbp6 non-coding downstream 206679 8669016 ~ 8739984 (-)
G149068 NA non-coding downstream 363207 8529067 ~ 8583456 (-)
G149268 pygl,LOC104938237 non-coding upstream 399957 9361332 ~ 9363435 (-)
G149322 NA non-coding upstream 528894 9490269 ~ 9490806 (-)
G149324 NA non-coding upstream 532784 9494159 ~ 9496132 (-)
G149325 NA non-coding upstream 534858 9496233 ~ 9496585 (-)
G149326 LOC107379822 non-coding upstream 535472 9496847 ~ 9497214 (-)
G149011 NA other downstream 839824 8095965 ~ 8106839 (-)
G148851 gpx2 other downstream 1583971 7361222 ~ 7362692 (-)
G148692 LOC107756589,LOC107552947,LOC107682372,LOC100534413,LOC105015666 other downstream 2383358 6556705 ~ 6563305 (-)
AMCG00000190 cyp1c1,cyp1c3,cyp1c2,LOC107745367,LOC106610849 other downstream 2730222 6214005 ~ 6216441 (-)
AMCG00000189 NA other downstream 2736706 6207514 ~ 6209957 (-)
AMCG00000260 gpr137c,LOC107583456,LOC107693135,LOC107723581,LOC107564956,LOC107751764,LOC106610616 other upstream 64965 9026340 ~ 9045855 (-)
AMCG00000270 gbg2,gng2,LOC108239039,LOC106603227,LOC107569409 other upstream 208708 9170083 ~ 9188266 (-)
G149321 NA other upstream 526504 9487879 ~ 9488609 (-)
G149341 sos2 other upstream 579236 9540611 ~ 9541259 (-)
G149395 NA other upstream 795006 9756381 ~ 9766794 (-)

Expression



Co-expression Network