AMCG00003093 (alox5,alox5a,lox5,LOC107678516,LOC107589586,LOC107747471,LOC107708393,LOC107582511)


Basic Information

Item Value
gene id AMCG00003093
gene name alox5,alox5a,lox5,LOC107678516,LOC107589586,LOC107747471,LOC107708393,LOC107582511
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030139.1
NCBI id CM030139.1
chromosome length 23121578
location 11309690 ~ 11331126 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00003093
tgagcgaGCAAGTAAGTGAGAAGATGTTTCACCTCTGGGAAAGAGGAAATCATTTGGTAGCTTGACATTACAGTCAAATCAGAGAACTTCAGAATAACAGACAGACTATAAAGCCTGGCTGAAATATTCAGTTTCTAAGAGTgacttctgttctgtttttccgTTGATCCGTGATGCCGTGCTACACTGTGACTGTGGCAACTGGTAGCCAGTGGTTTGCTGGGACCGATGATTACATTTATCTGACTCTGGTGGGAACTGAAGGATGCAGTGAGAAGTCTCTGCTGGATAAAGCACTCTATAATGACTTTGAGAGAGGGGCTGTTGATTCCTATGATGTTAATGTAGCAGAAAACCTGGGTGAAATCCAGCTGGTGAAAATCGAGAAGCGCAAGTACTGGGTGCAGGATGACTGGTACTGCAAGTACATCACAGTGAAAACTCCGGAGGGGGACTATGTCGAGTTTCCATGCTATAGATGGGTCACTGATGACAAGGAGATAGTACTCAGAGATGGCAAAGCACGGCTGGCCCAGGATGACAAAACGAGACTGGCGAAGGAACACAGACGCAAAGAACTGGAAACAAGACAAAAGCTGTACAGGTGGAAAGAGTGGCACCCAGGATTCCCCATGAGCATAGACGCCAATGCTCACAAAGAGCTTCCCCGTGACATTCAGTTCGATAGTGAAAAAGGAGTGGACTTCATCCTCAACTACACAAAAGCGATTGAGAACCTCTATGTCAATCGGTTCATGCACATGTTCCAGTCATCTTGGAGTGACTTTGCAGACTTTGAGCAGATCTTTGTGAGGATCAGTAACACAATCTCAGAGTATGTCATGCAGCACTGGCAGGAGGATTTCATGCTTGGCTATCAGTTCCTGAATGGCTGCAATCCTGTCATGATAAAGAAATGTACTGAGCTGCCCAAAAAGTTTCCAGTCACCCACGAGATGGTGGAGTTCTGCCTGGAGAGAAACCTCACTCTGGAGGAGGAAATAAAGAATGGCAATATTTTTATTGCAGACTATGAACTTCTAGATGGTGTTTCTGCAAACTGTACCGATCCATGCACCATTCAGTATTTGGCAGCCCCCATTTGCCTTCTGTACAATAatttacagaacaaaatgcTTCCAATTGCTATTCAGCTGGGTCAAACCCCAGGAGACGACAATCCAATTTTTTTGCCAAGTGATGCAAAATACGATTGGATTCTGGCAAAAATATGGGTGCGATCTTCCGACTTCCACATTCACCAAACTGTCACTCATCTCCTGCGGACACATCTGATTTCAGAGGTTTTTGGGATTGCCATGTTTCGCCAACTTCCAGCTGTCCACCCCATCTTCAAGCTGCTCCTTCCCCATGTGCGCTTCACAATTGCGATTAATACAAAGGCTCGAGAGCAGCTTATCTGCGAGTGTGGGCTCTTTGATAAGGCCAACGCAACAGGTGGAGGGGGCCACGTTCAGTTAGTACAGCGCTCCATGAAGGAATTCACGTACACATCCATGTGTTTTCCTGAATCCATAAAAATGAGAGGGTTGGAAAGCCAGGAAGATATCCCCTATTATTTTTACAGAGATGATGGGTTAAAAGTCTGGGAGGCCACCTTGAGCTTTGTGGAAGAGGTTGTGAATATGTACTACAAAAGCGATGAAATGGTACAGAAGGATGAAGAGATCCAAGCCTTTGTTAAAGATGTGTGCGTCTTTGGGATGCAGGACAATGAATATTCAGAGTTTCCCAAGACTATTAAAACCCGAGAGAAGCTAATTGAATATGTGACTGTGGTGATTTTCACTGCTTCTGCACAACATGCTGCTGTCAATTTTGGGCAGTACGACTGGTGTTCCTGGATTCCCAACTCTCCCCCCACCATGCGCCGCCCCCCGCCCACAGAGAAAGGTATCACCACCATTGAGTACATTATCGAGAGCCTGCCTGACCGGGGCCGGTCCTGCTGGCATCTGGGAGCTGTCTGGGCCCTTAGCCAGTTCCAGGAAAATGAAttgTTCTTGGGCATGTACCCTGATGAACATTTCATCGAGAAGCCAGTGAAGAAGGCCATTGAGAAGTTCCAGAAGAAACTGGATGAGATCTCCAGCTTTATAAAGGAcaggaacaagaacaagaagctTCCCTACTACTACCTCTCACCGGACAGGATCCCAAACAGTGTTGCCGTTTAACTGTATGAGAGAGCAGATTTTGATTACCAAGTCTTAGAGAGCaaaaaaaattgataaaaaaaaaaaaaaatctggattgTTTGCGgtgtttatatttgaaatggtGGATTCAAAACACACCATATTTGGATAATTGACAAAGTTCATTGTTGTAATTCAGGCTTGAAATGTGTATGatgtcgtttttttttctttaggtgATTAAAATGGCACGAAAGTAAGGTGCTCATATATGGATTTCTACAGTAAGCcttattttgttcattattagTGTTATAATGGTCAACAATTTATAGAATGTCTTTCTTTGTAACAAAcattgcaaattattatttaaaaggctCACCCCAATGAGCtgaggctatatatatatatatatatacacatacacacaatgaaatatacatgtaattcaTGCTTGAACTGAACAAtaagcaagaaacaaaaaaaacaaaaaaaaacagctaacaATATACTCTCATATTTGTATTCTAGGAACATTTTTACCTGGATAAAAAGTGTGATATTGTGTTTTACACAAAttgcttgcttgacaattaGCC

Function

symbol description
alox5a Enables arachidonate 5-lipoxygenase activity; arachidonic acid monooxygenase activity; and leukotriene-C4 synthase activity. Acts upstream of or within arachidonic acid metabolic process. Predicted to be located in cytoplasm. Predicted to be active in nuclear envelope. Is expressed in pronephric duct. Human ortholog(s) of this gene implicated in artery disease (multiple); asthma (multiple); pancreatic cancer; and pulmonary tuberculosis. Orthologous to human ALOX5 (arachidonate 5-lipoxygenase).
alox5 Enables arachidonate 5-lipoxygenase activity and iron ion binding activity. Involved in several processes, including leukocyte chemotaxis involved in inflammatory response; leukotriene A4 biosynthetic process; and lipoxin biosynthetic process. Located in cytosol; nucleus; and perinuclear region of cytoplasm. Implicated in artery disease (multiple); asthma (multiple); pancreatic cancer; and pulmonary tuberculosis. Biomarker of several diseases, including cholangiocarcinoma; common cold; pancreatic cancer; pulmonary fibrosis; and pulmonary hypertension.

NR:

description
PREDICTED: arachidonate 5-lipoxygenase

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen molecular_function
GO:0005506 iron ion binding molecular_function

KEGG:

id description
K00461 ALOX5; arachidonate 5-lipoxygenase

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00003093 True 2761 mRNA 0.43 14 11309690 11331126

Neighbor

gene id symbol gene type direction distance location
AMCG00003094 slc25a16 coding upstream 2208 11300317 ~ 11307482 (+)
AMCG00003096 NA coding upstream 70386 11233448 ~ 11239304 (+)
AMCG00003090 NA coding upstream 155589 11146588 ~ 11154101 (+)
AMCG00003091 rufy2,LOC107725492,LOC107743555 coding upstream 169864 11118965 ~ 11139826 (+)
AMCG00003092 NA coding upstream 204337 11052987 ~ 11105353 (+)
AMCG00003095 NA coding downstream 259 11331385 ~ 11356730 (+)
AMCG00003108 NA coding downstream 171901 11503027 ~ 11504004 (+)
AMCG00003109 NA coding downstream 215275 11546401 ~ 11548788 (+)
AMCG00003107 NA coding downstream 240739 11571865 ~ 11600042 (+)
AMCG00003111 LOC106513751,LOC107375490,LOC103376442,LOC108239168 coding downstream 455296 11786422 ~ 11797059 (+)
G140632 eif4e1c,LOC108444323,LOC103032634,LOC107708453,LOC107690176 non-coding upstream 62412 11245256 ~ 11247278 (+)
G140612 NA non-coding upstream 100188 11207506 ~ 11209502 (+)
G140436 NA non-coding upstream 652699 10653333 ~ 10656991 (+)
G140435 loxl4,LOC103368016 non-coding upstream 677201 10632263 ~ 10632489 (+)
G140434 NA non-coding upstream 681808 10624763 ~ 10627882 (+)
G140692 NA non-coding downstream 149679 11480805 ~ 11481037 (+)
G140694 NA non-coding downstream 157104 11488230 ~ 11490662 (+)
G140723 NA non-coding downstream 206521 11537647 ~ 11537954 (+)
G140738 NA non-coding downstream 300837 11631963 ~ 11633525 (+)
G140857 NA non-coding downstream 823687 12154813 ~ 12158751 (+)
G140613 NA other upstream 97579 11209573 ~ 11212111 (+)
G140478 nkx23,LOC106591187,LOC101065636,LOC101073339,LOC101063040,LOC104962797 other upstream 552850 10754901 ~ 10756840 (+)
AMCG00003066 LOC105931228,LOC105012084,LOC107588449,LOC107706116,LOC108435714,LOC103374338,LOC103154480 other upstream 626078 10680771 ~ 10683612 (+)
AMCG00003019 NA other upstream 1456237 9844776 ~ 9853453 (+)
G140189 NA other upstream 1529238 9778250 ~ 9780452 (+)
G140693 NA other downstream 155065 11486191 ~ 11487884 (+)
AMCG00003129 rab11fip2,LOC107585298,LOC107733785 other downstream 1040873 12371999 ~ 12678159 (+)
G140939 NA other downstream 1399605 12730731 ~ 12739767 (+)
AMCG00003141 LOC105923605 other downstream 1547559 12878685 ~ 12882998 (+)
AMCG00003158 NA other downstream 1775330 13106456 ~ 13110634 (+)

Expression


Co-expression Network