AMCG00003782 (ctsb)



Basic Information


Item Value
gene id AMCG00003782
gene name ctsb
gene type misc
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information


Item Value
chromosome id CM030121.1
NCBI id CM030121.1
chromosome length 57050121
location 18146660 ~ 18152381 (-)
genome version AmiCal1_2021_bowfin_Genome

Sequence


>AMCG00003782
GATGTGGCGTTTGGCTGTGCTGTGCGTTCTGGCGGCTGTGTGTGGGTCGAGAGCCCGGCCACACCTCTCACCCCTGTCCCCTGAGCTTGTGAACTACATCAACAAGATTAACACCACCTGGAAGGCTGGACACAATTTCCCCAATGCTGACTTCAGCTATGTGAAGACTCTGTGTGGGACTCTGCTGAAGGGCCCCAGACTGCCAGTGATGGTGCAGTACGCTGATGACATAAAGCTACCGAAGAGCTTCGACCCTCGGGACCAGTGGCCCAACTGCCCCACCCTCAAGGAGATCCGAGACCAGGGCTCCTGTGGATCCTGC
>TU3909
CGGGGCGCTTATTAGCGATGCGGAACTGAGTTGCTGTGCAGAAGGTCGGACGGTGTGCGGAGGACGGCGGAGATCTTACACGATTACAGGATGTGGCGTTTGGCTGTGCTGTGCGTTCTGGCGGCTGTGTGTGGGTCGAGAGCCCGGCCACACCTCTCACCCCTGTCCCCTGAGCTTGTGAACTACATCAACAAGATTAACACCACCTGGAAGGCTGGACACAATTTCCCCAATGCTGACTTCAGCTATGTGAAGACTCTGTGTGGGACTCTGCTGAAGGGCCCCAGACTGCCAGTGATGGTGCAGTACGCTGATGACATAAAGCTACCGAAGAGCTTCGACCCTCGGGACCAGTGGCCCAACTGCCCCACCCTCAAGGAGATCCGAGACCAGGGCTCCTGTGGATCCTGCTGGGCTTTTGGGGCAGCAGAGGCGA

Function


symbol description
ctsb Enables collagen binding activity; cysteine-type endopeptidase activity; and proteoglycan binding activity. Involved in several processes, including cellular response to thyroid hormone stimulus; collagen catabolic process; and proteolysis involved in cellular protein catabolic process. Located in extracellular space; lysosome; and perinuclear region of cytoplasm. Colocalizes with collagen-containing extracellular matrix. Implicated in diabetes mellitus. Biomarker of several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); glioblastoma; intracranial aneurysm; and type 2 diabetes mellitus.

NR:

description
cathepsin B precursor

GO:

id name namespace
GO:0031101 fin regeneration biological_process
GO:0006508 proteolysis biological_process
GO:0050790 regulation of catalytic activity biological_process
GO:0004197 cysteine-type endopeptidase activity molecular_function

KEGG: NA

RNA


RNA id representative length rna type GC content exon number start site end site
AMCG00003782 False 322 mRNA 0.58 3 18147201 18148709
TU3909 True 436 TUCP 0.50 5 18146660 18152381

Neighbor


gene id symbol gene type direction distance location
AMCG00003780 NA coding downstream 22365 18105088 ~ 18124295 (-)
AMCG00003778 LOC107594834 coding downstream 119034 18004171 ~ 18027626 (-)
AMCG00003777 NA coding downstream 145846 17970812 ~ 18000814 (-)
AMCG00003776 NA coding downstream 249745 17889983 ~ 17896915 (-)
AMCG00003770 LOC107585532,LOC107675519 coding downstream 270074 17875147 ~ 17876586 (-)
AMCG00003781 LOC103364986,LOC107735240 coding upstream 4477 18156858 ~ 18161968 (-)
AMCG00003783 NA coding upstream 11245 18163626 ~ 18175704 (-)
AMCG00003789 NA coding upstream 57320 18209701 ~ 18215100 (-)
AMCG00003788 H3F3A,h3f3b,LOC105909691,LOC102696298,LOC107388308,LOC101073377,LOC107572204 coding upstream 63405 18215786 ~ 18220738 (-)
AMCG00003791 eva1a,LOC107593306,LOC107719434 coding upstream 70364 18222745 ~ 18226922 (-)
G3170 odc1,LOC107687948,LOC107753348,LOC107758719,LOC107687839 non-coding downstream 205948 17935840 ~ 17940712 (-)
G2972 NA non-coding downstream 887117 17257937 ~ 17259543 (-)
G2973 NA non-coding downstream 891895 17254271 ~ 17254765 (-)
G2902 NA non-coding downstream 1104111 17041437 ~ 17042549 (-)
G2903 NA non-coding downstream 1149056 16996790 ~ 16997604 (-)
G3257 NA non-coding upstream 257489 18409870 ~ 18418066 (-)
G3266 NA non-coding upstream 286720 18439101 ~ 18439510 (-)
G3270 NA non-coding upstream 392972 18545353 ~ 18545976 (-)
G3354 NA non-coding upstream 723201 18875582 ~ 18878573 (-)
G3374 NA non-coding upstream 797391 18949772 ~ 18950252 (-)
AMCG00003784 NA other downstream 3979 18135379 ~ 18142681 (-)
G3181 NA other downstream 201718 17942577 ~ 17944942 (-)
AMCG00003751 NA other downstream 1006278 17137248 ~ 17140382 (-)
AMCG00003742 kif26ba,LOC107693166,LOC107682227,LOC107589674,LOC107586651,LOC107729288 other downstream 1275185 16868332 ~ 16871475 (-)
AMCG00003734 NA other downstream 1518259 16607410 ~ 16628401 (-)
AMCG00003825 NA other upstream 1209437 19361818 ~ 19373225 (-)
G3517 LOC101154678 other upstream 1272582 19424963 ~ 19425366 (-)
G3523 NA other upstream 1291635 19444016 ~ 19506753 (-)
AMCG00003893 NA other upstream 5377138 23529519 ~ 23533882 (-)
AMCG00003896 tmem181 other upstream 5588204 23740585 ~ 23757796 (-)

Expression



Co-expression Network