AMCG00006529 (smo,LOC106609777,LOC104956154)


Basic Information

Item Value
gene id AMCG00006529
gene name smo,LOC106609777,LOC104956154
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030134.1
NCBI id CM030134.1
chromosome length 29342575
location 7955026 ~ 7966534 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00006529
aaaaaagccaAGCAGACACGGCAacgaaagagaaaaacaaacgcCAAACCTCCCCATGAACAGCAGTAACGCACAGGGAGCCCTGggaagctttttatttatttatttgataacacatgcattttgtgaaattgtgaaaaagTGACACTTTTCAGCAGGCAGGAAGAAGCGAACCGTGCGGATCAGATTTCAGCGTTTCAGACTCTTCAtgtcaaaagttttttttcttccaccaaAAAAAGTGGGGGGATGGTGGAAGTGGCTCTTTCTGTAAAGTGATCTAACTCAACAGGACGGGACGAGATCTTTTCAACCCCGATGTTGTGTTTTCCGTTAAACCTAATCCCGTTATAAATGTGGCAGAAGAGGGAAGGATGAGGAGTGACCGAAAGGAGTGAATGAGGATTGATCCCGGGCTGGGACAGGGAGCAGAGTTGCGCCGCACGGAGAGACACTGTTTCCTTTCATGGGAGTTGAGGATGCATCTGCTGGAGATGTTTCTCCTAATGTCACTAAGTGTATCTTTGTAACACAATAACCGATACTGCAACTTGTGGAGTTCGGCTCAATCCTCTGAAACAAGAGTTGCGAGGCTCAAGCTTTCCAAGATGTCCTCCCGAGTCTGTCCCTTTGTTGGGAGATGCGGGATGCTGCTGCTCTGGGGTGCCTACTTCTTGCTCGCCCGTGTGGGCACGGCACAGAAAAACGACACGGGGGTCCTGGATTATTGTCAGAAAAGTTCAACCTGTGAAGTCCTGAAGTACAACACCTGCCTGGGCTCCCCGCTGCCCTACACGCACACCTCCGTGCTCCTGGCCGAGGACTCCAGCACCCAGGACGAGGCTTTCGAGAAACTGGCCATGTGGTCCGGTCTGCGCAATGCCCCTCGCTGCTGGGCCGTCATCCAACCCCTGCTGTGCGCCGTCTACATGCCCAAGTGTGACAACGGCAAGGTGGAGCTGCCCAGCCAGAGCCTGTGCCAGGCCACCCGGCGCCCCTGTGCCATTGTGGAGCGTGAGAGAGGCTGGCCAGACTTCCTCAAGTGCACTACCGACAAGTTCCCTGTGGGCTGCCAGAATGAAGTCCAGAAGATCAAGTTCAACGCGTCGGGCCACTGCGAGTCCCCGCTGGTGAAGACGGATAACCCCGCTAGCTGGTATGAGGATGTGGAGGGCTGCGGCATCCAGTGCAACAACCCACTATTCACCCAGGAGGAGCACAGCGACATGCACGTCTACATCGCCGTGTTCGGCTCCCTCACACTCTTCTGCACCTTCTTCACACTGGCCACCTTCGTAGCCGACTGGAAGAACTCCAACCGCTATCCCGCCGTCATCCTGTTCTACGTCAACGCCTGCTTCTTCATCGGCAGCATCGGCTGGCTGGCCCAGTTCATGGACGGAGCGCGGCAGGAGATCGTGTGCAAGAGCGATGACACCATGAGGCTCGGGGAACCCACGTCCACGGAGACGCTGTCCTGCGTGATCATCTTCGTGATCGTCTACTACTCCATGATGTCGGGGGTCATCTGGTTTGTCATGCTCACCTACGCCTGGCACACCTCCTTCAAGGCCCTGGGCACCACTTACCAGCCTCTGAGCGGCAAGACTTCCTACTTTCACCTCTTCACCTGGTCCATCCCCTTCGTGCTGACTGTGGCCATACTGGCAATCAAACAGGTGGACGGAGACTCGGTCAGCGGCATCTGCTTTGTCGGCTATAAGAACTACAACTACAGAGCTGGGTTTGTGTTGGCTCCCATAGGTGTCGTCCTCGTCGTGGGGGGCTATTTTCTCATCCGAGGGGTCATGACATTGTTTTCGATTAAGAGCAACCACCCAGGGCTGCTGAGTGAAAAAGCTGCAAGCAAAATAAACGAGACAATGGTCAGACTAGGTATATTTGGATTCCTTGCctttggctttgtttttattacgtTTGGCTGCCATTTCTATGACTTCTTCAACCAGGCGGAGTGGGAGCGCAGTTTCAGAGAATATGTCTTGTGTGAGGCGAATGTGACGATTGCGGTCCAGACCAACAAGCCCATCCCCGAATGTGCCATTAAGATCAGGCCCAGTCTGCTGGTGGTGAAGATCAACCTCTTCGCCATGTTTGGCACCGGGATCTCCATGAGCACCTGGGTGTGGACCAAGGCCACCGTGCTCATCTGGAAACGCACCTGGTGCAGGATCACCGGTCGAAGTGACGACGAGCCCAAGCGCATAAAGAAGAGCAAGATGATCGCGAAAGCCTTCTCCAAACGCAAGGAGCTGCTGCGCAACCCTGAGAAGGAGCTGTCCTTCAGCATGCACACCGTCTCCCACGAGGGGCCCGTGGCTGGTATAAACTTTGAGTTGAACGAACCGTCAGTGGACATGTCCTCTGCGTGGGCCCAGCATGTCACCAAAATGGTGGCCAGGAGAGGAGCCATTCTGCCACAGGATATCTCCGTCACCGTCACGGGCACACCAGTGCCACCCGATGACAACATGAACCAGCTGTGGATAGTGGAGGCAGAGATTCCCCCGGAGCtgcagaaaaagaagaagaaaaagcgGCGGAGGAAGAAGGAGGTGCGTCCCCTGGCGCCCACAGAGGAGCTGTGTGACCTGGGCCGCCGGGGGGAGCGTGCCCACAGCGCAGTGCCGCGCCTGCCCAAGCTGCCCGGACACCGCAGCCTGGTGGCCACCGTGCGGGAGCAGCACCCGGAGGAGCTCCTGCCCGGCTCCTTCCCCGAGATCAGGCCCAGCACGCCCCCGCCGTCCTACCGCTCGGACAACCGCCGGTACCCTGCGCTCGGCGTGCCCTACGGGGACTGGGCACGGGAGGACCACGACTTCTCCAGCAGCACTCGGTTCCGCCCCCCACCCCGGGATTGCAACGGCATGTTCCGCCACTCGGCTGGGGAGGGTACGCTGATGGCGGGCAGCTCGGGGAACGTGCCCTACATCCCCAGGACTCAGGGCAGGAGAGCGGGCCTCGCGCCCATCCACTCCAGGACCAACCTCATGGACGCACAGCTGATGGACGCAGACTCTGACTTctgaggggagaaaaaaacactacaaTACAGTGAGGGTGTTTGTACAGTTTGTGAGGACGAAGTGCTGGATACTTTTAGACTTGCTCCCACTTGGCCATCTAAGAAGAGGAAAGTAACATAGTCTTGACCTAGATAAGTGCTTCCtgggaattaaattaaataataaaaattgtaataaaggGAAGGGTTGCAGGTAACCCCTTCAGACTACCAAAAATGACAAGTCCTGTTTACTGTGGTCCATTTACACAGTGGTAACGTCATAATATGCTGGAGTGCTTTTTACAATCAGCTTTTAAACCTTTTACTTGCAGCTGTCCATTTTTGTTACTCcatgaataacaaaacaaatcccacTGGAGTGTTTCTGTCTCATGAACAGCAGAGGAAATCTGACAAGGTGGcccatgaaaatgaaatgtaccgAAAACTCGATTCGACCTGTTTGGTGTGGATCTATAATGTTTGTTCAGATGGATTAATTTCACGTCGTGATCCGCTGCTGAAGAGGAAACCTTCTCTGCACAAGACCCTACCCAGCTTAGCGGAAACTAAGCACTGTTGTGTGTTAATGGATTAATGTCCTCTCCGGCACCGAAAAAACACACTAGCTTTTGCTCAAcctcttttattttgttgatgttgaGTTTGGAGTGTTACCTGCAATATCTAGTGCTCTAGAGGGCAAAAACATTTAGGATAAAATGTGCTTAACCGCTTACAATTGCTGAACTTCAGCAACAGAGGAAATTCTTAAAGGGGAGTAAAAGCCAAGTAAACTTCCTCAgattctgatttaattttccaATAGAAAAACAGGTAAATAACTTGTTGGTGGATTAACTTtttaatataagtatatatattatagtctTCTGTTGGACGCATTTCAGTACAAAACAACGTTTGACACCGATTCGTATTCATTTAAAGGGACCAGCTTTTTCAAATACACCAATGTTGGATACAAAAGATTTGAGTTCTTGCTAGTTTCTTCCCAATGGTCCCTCAGTGACTTGACAGTGTGCCTGGTAAACCTACAATGGTGGGTTGGACGTATCTACCACCTGTTCTATGGTCTGTACTACTTCTATGAACATGGTGAATTCACTGCTATTGCTATTGTGATGTTCAGAAATCTAGTGCCAGGCCACACAAGTGATCCTGTGATAGTACAGGAAAGGGAAAGCTTGTCCTTCCTTCTTTCTTAGGTAAGGAAGACAGCGGCTCTAATGCATAGATTGTCTTCAGACTCACAGTGCGTCCCAACTCCGCAAGTGCCATGCAAGCCTACCAGTGTCATTTCATAGAGAGGCATATGAAGTAAGAGTATGTTGCGCCTCTCCTTTgtttcactgtatatatttctggTTCATTTCAGCCGCACTCTTGATACACAGTATTGTCTAAGCTAAGTATAGTTCCTCTTGTGTTTTCGCGAGGAACTGCGCTCTGCTCTTGAGCTATGCGAAGGGTTCACGTGGACTACTATTGCTTTGGCATTGAACTGCACAAGCCAGCTATCAAAATGTTGTGTTATATCTGGAGAAATCACTCATCCGTTCACTTTTTGTGCATTAGGGCACCTCATTACGGGGAGCATCATGTTGCAGTACTTCACAGTAATGCAgtaacagtatttattaaaactaaaaggtcttaattgcttttACTAAATTATACAACAGTAGAAACTaatggtattttgttttaatccgatttatttatatagctgTCATGCTTCTGTAGTTCCCATGTCTTTCAGGATTTCATTACTATCAGGTCCATGCAAAAGATGTAAGATAAggacttgtttttgttttctgcctgtagatagagagggggagagatagagagatgtTTACAATGACTTCAGAATGCAGCATACATTTCCCCATCATCCCCCAAACCTTATGGAGGCGGTTTAGTTGTTATATTATGAGGTACTCAGATCACAAACATTGGCATTACACTGTACATATAATTAACTCATAATATAGggatgaaaaatacatatacattatttgacCATCTTTATCTTTTCATTGTTTCCATAGTTgctgattgttttaaaatcatgcATTACTTCGGTATCCTAAAGTACAGGCAGTTCACAGCTCTCAGCCACGCATTTTTGACCggctttaatatatatttatatgcactAAAACCTTTTTTGTGATTAAAGTATTTATCTGCAGGATTATCAAACATAAAGTTCAATGCAATGACATGGAAGCTAAATGCTATTGTAGCCCCCAAAATTGCAGTAATCCAAAAGGTGATCTTCTTCACAGcactttacattaaaaaaaacatcaagaacTCAAGTCGCAATGGTGatggtaaacaaaaacaaaatgctcatTGCTGTGGGCCAGTATTATTTAAGTCAACCCAGGGTAATTTTGGACATACGTTTATATATCACCATTTTCTACAAACAATTTTTCCTTAGGATTAGGGTGATTCAACTTCTATTAACCTTTTCTATCTCACATTTGTagaaatttgtttattttttgaatgacaCTTCTAACGAATGTGTTCATCCGGATCAGTTCAGCCAGTGAAAGAgtatctgtgtctctctgggACGTTGAACATGACCAGATCCcacacaacattttttgttggcTTTCCCCCCAAAATGAATTGTGCCAACTTGATCAAAGCATGGTCGTATTGTTTGGGCATGGGATCCTAATATAATATTCAACACTGTGTGATTGATTAAATTGGTGTACATCTGGCCAGTTCCCAACATTGTTACAAATACTCTTTATGTGTTAGTGATTAACCattgaaatgtctttgtttgcCTTTAACATTTCAATATCATATTATGTAGGTGTGTGGAAAAGAGTAACACATCCTGCAGGATCAGAGTTTTAAAAGATCTATTTACTGACTATTGAGCACATTCAGTAAACTTGTATTTTCCATGATCAGAAGTATAAATACTGAGAAAATGGCAGCTGTAGAAGATTCTAACTGTAACACTGAACAGCAATGTagagttttcctttttcttttttaataaggAATGATGTGGTAAAGTTTTACACAACATGAAAATGGTTTCTTGCCTACTGTTGTTACTAAAATCTTTTTCTGCTATTAATCTtattaaagatgttttttttattcacagtaTTGTTAAAAGGCTATCactcaattgtatttttgtatgtgtaaataaac

Function

symbol description
smo Enables oxysterol binding activity. Acts upstream of or within several processes, including animal organ development; blood vessel development; and nervous system development. Located in cilium. Is expressed in several structures, including brain; mesoderm; pectoral fin bud; tail bud; and trunk. Human ortholog(s) of this gene implicated in basal cell carcinoma and pancreatic ductal carcinoma. Orthologous to human SMO (smoothened, frizzled class receptor).

NR:

description
PREDICTED: smoothened homolog

GO:

id name namespace
GO:0021523 somatic motor neuron differentiation biological_process
GO:0060070 canonical Wnt signaling pathway biological_process
GO:0042693 muscle cell fate commitment biological_process
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0008406 gonad development biological_process
GO:0048741 skeletal muscle fiber development biological_process
GO:0021537 telencephalon development biological_process
GO:0021798 forebrain dorsal/ventral pattern formation biological_process
GO:0048745 smooth muscle tissue development biological_process
GO:0048752 semicircular canal morphogenesis biological_process
GO:0021561 facial nerve development biological_process
GO:0060896 neural plate pattern specification biological_process
GO:0001755 neural crest cell migration biological_process
GO:0031290 retinal ganglion cell axon guidance biological_process
GO:0048795 swim bladder morphogenesis biological_process
GO:0031017 exocrine pancreas development biological_process
GO:0002052 positive regulation of neuroblast proliferation biological_process
GO:0031018 endocrine pancreas development biological_process
GO:0002053 positive regulation of mesenchymal cell proliferation biological_process
GO:0009880 embryonic pattern specification biological_process
GO:0042475 odontogenesis of dentin-containing tooth biological_process
GO:0051216 cartilage development biological_process
GO:0007283 spermatogenesis biological_process
GO:0048557 embryonic digestive tract morphogenesis biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0060956 endocardial cell differentiation biological_process
GO:0050679 positive regulation of epithelial cell proliferation biological_process
GO:0048846 axon extension involved in axon guidance biological_process
GO:0021904 dorsal/ventral neural tube patterning biological_process
GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning biological_process
GO:0001839 neural plate morphogenesis biological_process
GO:0030239 myofibril assembly biological_process
GO:0031076 embryonic camera-type eye development biological_process
GO:0014003 oligodendrocyte development biological_process
GO:0001570 vasculogenesis biological_process
GO:0009952 anterior/posterior pattern specification biological_process
GO:0045880 positive regulation of smoothened signaling pathway biological_process
GO:0003231 cardiac ventricle development biological_process
GO:0035912 dorsal aorta morphogenesis biological_process
GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation biological_process
GO:0031102 neuron projection regeneration biological_process
GO:0021696 cerebellar cortex morphogenesis biological_process
GO:0032474 otolith morphogenesis biological_process
GO:0035143 caudal fin morphogenesis biological_process
GO:0010002 cardioblast differentiation biological_process
GO:0021984 adenohypophysis development biological_process
GO:0001649 osteoblast differentiation biological_process
GO:0060041 retina development in camera-type eye biological_process
GO:0048702 embryonic neurocranium morphogenesis biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0001947 heart looping biological_process
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway biological_process
GO:0021508 floor plate formation biological_process
GO:0035479 angioblast cell migration from lateral mesoderm to midline biological_process
GO:0060844 arterial endothelial cell fate commitment biological_process
GO:0021520 spinal cord motor neuron cell fate specification biological_process
GO:0043025 neuronal cell body cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005929 cilium cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0030165 PDZ domain binding molecular_function
GO:0042813 Wnt-activated receptor activity molecular_function
GO:0017147 Wnt-protein binding molecular_function
GO:0004930 G protein-coupled receptor activity molecular_function

KEGG:

id description
K06226 SMO; smoothened

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00006529 True 6250 mRNA 0.47 12 7955026 7966534

Neighbor

gene id symbol gene type direction distance location
AMCG00006531 NA coding upstream 4046 7936383 ~ 7950980 (+)
AMCG00006535 psmc2 coding upstream 43664 7907694 ~ 7911362 (+)
AMCG00006534 pmpcb,LOC106576546 coding upstream 55035 7896187 ~ 7899991 (+)
AMCG00006532 NA coding upstream 77855 7873074 ~ 7877171 (+)
AMCG00006528 NA coding upstream 96235 7846969 ~ 7858791 (+)
AMCG00006533 NA coding downstream 1457 7967991 ~ 7981094 (+)
AMCG00006539 NA coding downstream 27397 7993931 ~ 8000522 (+)
AMCG00006540 ube2h,LOC105888480,LOC107676921 coding downstream 60156 8026690 ~ 8034832 (+)
AMCG00006546 NA coding downstream 256347 8222881 ~ 8244037 (+)
AMCG00006551 NA coding downstream 677708 8644242 ~ 8660293 (+)
G110361 NA non-coding upstream 40198 7913850 ~ 7914828 (+)
G110286 NA non-coding upstream 259513 7694554 ~ 7695513 (+)
G110243 NA non-coding upstream 321907 7593287 ~ 7633119 (+)
G110245 NA non-coding upstream 621856 7327030 ~ 7333170 (+)
G110240 NA non-coding upstream 714469 7240086 ~ 7240557 (+)
G110429 NA non-coding downstream 121503 8088037 ~ 8090127 (+)
G110439 ahcyl2,LOC102228098,LOC105933830,LOC106941354,LOC103156365 non-coding downstream 166561 8133095 ~ 8135492 (+)
G110444 NA non-coding downstream 206794 8173328 ~ 8175573 (+)
G110446 NA non-coding downstream 211987 8178521 ~ 8178728 (+)
G110447 NA non-coding downstream 212907 8179441 ~ 8179688 (+)
G110279 NA other upstream 299832 7653672 ~ 7655194 (+)
G110163 LOC100846954 other upstream 1042772 6911876 ~ 6912254 (+)
AMCG00006501 fam19a5,LOC107552289,LOC106561036,LOC107721159,LOC103356475 other upstream 1366627 6519865 ~ 6588399 (+)
G110023 NA other upstream 1972117 5979062 ~ 5982909 (+)
AMCG00006459 NA other upstream 2820311 5127357 ~ 5134715 (+)
G110445 NA other downstream 209226 8175760 ~ 8176786 (+)
AMCG00006552 NA other downstream 744216 8710750 ~ 8724066 (+)
AMCG00006565 LOC103366858,LOC103380581 other downstream 1597418 9563952 ~ 9568276 (+)
AMCG00006624 NA other downstream 4179211 12145745 ~ 12323278 (+)
AMCG00006636 NA other downstream 4653528 12620062 ~ 12651815 (+)

Expression


Co-expression Network