AMCG00006617 (tbk1)



Basic Information


Item Value
gene id AMCG00006617
gene name tbk1
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information


Item Value
chromosome id CM030134.1
NCBI id CM030134.1
chromosome length 29342575
location 11987460 ~ 12000919 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence


>AMCG00006617
ACGACCCGTCTGTCGAATCGGAAAACGGGGGACCTCTATGCCGTCAAAGTTTTCAACAACCTGAGCTTCCTGCGGCCCCTGGATGTGCAGATGAGAGAGTTTGAGGTGTTGAACAAGCTCAACCACAAGAACATTGTGAAGCTCTTTGCCGTGGAGGAGGAGACGAACACCAGACACAAGGTGCTGGTGATGGAGTATTGTCCCTGTGGCAGTCTCTACACAGTCCTGGAAGAGTCTTCTAACGCCTATGGGCTTCCGGAGGATGAGTTTCTGATAGTACTGCAAGACGTGGTGGCCGGAATGAATCACCTCAGGGAATATGGCATTGTCCATCGCGATATCAAACCAGGAAACATCATGCGCATGATTGGGGAGGATGGCCGATCTGTGTATAAGCTGACTGACTTCGGAGCTGCCCGGGAACTCGAAGACGATGAGCAGTTTGTGTCGCTCTATGGGACTGAGGAGTACTTGCACCCTGACATGTACGAGAGGGCCGTCCTCAGGAAGGACCACCAGAAGAAGTACGGCGCCACGGTGGACCTGTGGAGCATCGGAGTGACCTTCTACCATGCAGCCACTGGCAGCCTGCCGTTCAGACCCTACGAAGGACCGCGCAGGAACAAGGAAGTCATGTACAAAATCATCACAGAGAAGCCAGCTGGGGCCATATCGGGACTGCAGAAGTTTGAAAACGGAAAGATCGAGTGGAGTTCAGAGATGCCAATCTCATCGGATCAGGAGAAGTGCTGGGGCTTCGATCAGTTTTTTGCAGAGACCAGTGACATCTTGCACAGGATAGTGGTGTATGTCTTCAGCTTACAGCAGGCCACTCTCCACCACATCTACATTCACTCATACAACACGGCAACACCGTTCCAGGAGCTGCTGTTCCGGAGAACCAACATCTCCCCTCCCAACCAGGAGTTGATGTACGAGGGCCGGCGGTTGGTGCTGGAGCCCAACAGGCAGGCGCAGAGCTTCCCCCACACCTCCCAGGACAATCCCATCATGCTGGTGAGCCGGGAGCTGGTGGCCACCATCGGACTGCTGTTCGAAGAGCCATCTCCTCCGAAGTTACAGCCCCGCTATGATCTGGATTTGGATGCAAGCTATGCAAAGACTTTTGCAGGGGATATTGGTCACCTGTGGAAGATATCTGGTGCCCTTTTGATGTATCAAGAGTTAGTCCGAAAAGGAGTCCGGGGCCTAATTGAATTGATGAAAGAAGATTATAACGAGACCGTGCATAAGAAGACGGAGGTTTTTCACATGTGCAACTACTGCAGTCAGACACTGGAGAAAACTGAGCAGCTgTGTGAAGCTCTGATCCAAGCAAATCTACTGTcaacagaaatgaatgaaatctCAGAGATCCGGAAGAAAATCATGCGGCTCACCAGCTCCCTAAGCTCGATGGAAAACAGTCTGCAGGATATTAAGAACAAGTTCATGGCTGGAGGTTTACTGACCGACGCCTGGGCACAACAAGTGGGCACCCATCCTGCGGACAGAAATGTGGAGAAGGTTGAAGTCCTCCTAAATTACATCACTGCAATCTACCAACAGTTTAAGAAAGATAAAGCAGAACGACGCCTGCCTTATAATGAGGAACAGATCCATAAGTTTGACAAGCAGAAACTCGTACTTCATGCCACGAAGGCAACCGCGCTGTTCAACGATGAGTGTGTAATGAAGTATCGGATCTTTCTCTCCAAGGCTGAGGAATGGATGAGGAAGGTTCATCATGTCAGGAAGCAGCTGCTGACTGTTACCAACCAGTTCATTAACATTGAACAGGAAGTGTCTGTATCCTTCGACCGGGTCTACCAGGAGTTGCTGCCCCAGAAGATCATGCCAGTGGCTTCCAGTGGAATAAAGCCCCAGGTGTATCTGAGTCAGAACACCCTGGTGGAGATGACCCTGGGAATGAAGAAACTGAAAGAGGAAATGGAAGGGGTTGTGAAAGAgctggaggaaaacaatcatTTTCTAGAAAGATTTGGTTCTCTGACCATGGATGGGGGAATGAGAAATGTTGACCGGATATGACCGCACAGCTCACCTCTCTGCCGGATGGAATGCCAATCAGGGCTTCCTCGCTCCTGATCTGAAGACCTCTCTGCTTTACGTCCTGGTATATATTCCTGTCTGTATATaggtctgtaaatatatattttaaaagaagtgcggattattttttattttgtatctataTGCCCCTGACCTTACGGACATTGCTTGCTGTAGCTGAAGGCTGCTATTGTAGAGGATATACTGATTCCATCGGCTCACTGACCTTAAAAAACGATGATAAAATAGTCCTTATGAAGCGAGTTCAGTTCCAAATCAATATCGGCAACTATGGGTTTATAAACCAAATTAATAACACACCATACTAATTACAGAACAGTTACCACACATACCTGTACATACTagctgttttattcattttgtactgtcatttgtcattttttggctttcagttgaaacaaaaatggAATCCAATAACTTTACTAGAttgtttattacaataaaagaAGGTTTCCGATTTAATAATGCCAACCGTAACATCTGCATCGGTGTTTTTGGttaactgcaaattaaaaaaaggaggCAATCAACCTAACATTTTCAACCTAAACAAGGAAGTGTGTGCTTCAGAAATGTCTTTGCTCTTTTCAGTTGAAGTATTTTTATGTGTGGTAACAACTCTTTAATCTGtaattgttttggaaaataaaaatacttttgagatGGCTGCCTTAGTATTACAAGCACTGTTACTTGATATACATTTCCTACATGGCAAGAATGTAAAAGGTAACCTCTGTGTGACTTTAATGATTTCTAATCTGTCAATATATGACTGAGATTCTACAGTCAAGGTCAATATCATTTCTTGAAGGCTATAACTTGTTCTTCAGTCAGTTTAACATGTTTATCTAacgatttatttttaattgggttaatatttatttttccttacacTGTTGATCACTTAAAAATACAAGATTGTTCTCCTCAGACCAaagtttttaaatgctttatatacATTCTAAAATGCCTATCCAGGCAAATTCCAATTACATAATCGTCAAAATCCCccaggaaaatgtaaaatcccaaacaaatggaaaaaataatccaTCAATATaagtacaatataaataatgaccACACAATTATTTACAGTGTCTAAGTGCGCCTTCCTGTGTTTTTTGATGAGGCAAACATACTCCAATAAATTCCACATCAGTTTAGAAAATGTGGGACTTAATCCTGGATGACAACGCCATACATTTTTCCTCTATTTGGGATGCCAATCTGAAATACACTACACAGTTTCCTAGTTCACCCAGCAATAGGAAAATCCAGTATATATGGACACAAAAGCTCACGGAGAGCCATTTGCAATGACTTATACAACATGGAAAAGGGACTTGTCTTAGACGTCCATCCTCCTCCTAATCaaaaatttaaatgattaaatgatttCTATATTGACTATGCAGTTTGAGAGTACCATGTTCACCGAGAACCACTAAATCATGGATGTTTTGTTGGGATGAGGAGGGTACATATTCCACAACATTAATCTATGTTAGGATAGATCCCTGTATTTTTCCAAGGGCATGCAGAGCAAGGGGACCACATATCAATGTCTTCTGCTAAATGTGTACTGCTCCATTCGAATCAGAACCAGTCTGGTttgatactgtactgtactgttctatatttatttaaagaatcaGTATAGTCATTCACACTTGATCTCTGGTTTAGAAATACCCAGACATGTTATGTGTATAATCGCTTCTCTGAAACTATCATGATATGTACAACCGATGGATGTATTGTAAATACTTATTTACTACCTGGGAATGGCACAGGatgctgaaataaaacattta

Function


symbol description
tbk1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in brain disease and frontotemporal dementia and/or amyotrophic lateral sclerosis-4. Orthologous to human TBK1 (TANK binding kinase 1).

NR:

description
PREDICTED: serine/threonine-protein kinase TBK1 isoform X1

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process
GO:0005524 ATP binding molecular_function
GO:0004672 protein kinase activity molecular_function

KEGG:

id description
K05410 TBK1; TANK-binding kinase 1

RNA


RNA id representative length rna type GC content exon number start site end site
AMCG00006617 True 3914 mRNA 0.43 20 11987460 12000919

Neighbor


gene id symbol gene type direction distance location
AMCG00006614 ptpro coding upstream 85414 11883937 ~ 11902046 (+)
AMCG00006608 syn3 coding upstream 197281 11773986 ~ 11790179 (+)
AMCG00006609 syn3,LOC106576044 coding upstream 251829 11734683 ~ 11735631 (+)
AMCG00006610 NA coding upstream 280636 11658887 ~ 11706824 (+)
AMCG00006606 NA coding upstream 665487 11305891 ~ 11321973 (+)
AMCG00006620 NA coding downstream 12167 12013086 ~ 12014321 (+)
AMCG00006616 NA coding downstream 30736 12031655 ~ 12054027 (+)
AMCG00006629 NA coding downstream 325916 12326835 ~ 12328153 (+)
AMCG00006630 LOC104940688,LOC102079147,LOC106573136,LOC104946814 coding downstream 331415 12332334 ~ 12333254 (+)
AMCG00006623 xpot,LOC102775766 coding downstream 355134 12356053 ~ 12374775 (+)
G110930 NA non-coding upstream 193925 11793168 ~ 11793535 (+)
G110916 NA non-coding upstream 315012 11671569 ~ 11672448 (+)
G110883 NA non-coding upstream 637343 11349884 ~ 11350117 (+)
G110849 NA non-coding upstream 866725 11120390 ~ 11120735 (+)
G110722 NA non-coding upstream 1617529 10369715 ~ 10369931 (+)
G111008 crebl2,crbl2 non-coding downstream 21891 12022810 ~ 12024549 (+)
G111063 NA non-coding downstream 349838 12350757 ~ 12353363 (+)
G111148 NA non-coding downstream 758652 12759571 ~ 12770925 (+)
G111161 NA non-coding downstream 845004 12845923 ~ 12847502 (+)
G111240 NA non-coding downstream 1353037 13353956 ~ 13357071 (+)
AMCG00006565 LOC103366858,LOC103380581 other upstream 2419184 9563952 ~ 9568276 (+)
AMCG00006552 NA other upstream 3263394 8710750 ~ 8724066 (+)
G110445 NA other upstream 3810674 8175760 ~ 8176786 (+)
G110279 NA other upstream 4332266 7653672 ~ 7655194 (+)
G110163 LOC100846954 other upstream 5075206 6911876 ~ 6912254 (+)
AMCG00006624 NA other downstream 144826 12145745 ~ 12323278 (+)
AMCG00006636 NA other downstream 619143 12620062 ~ 12651815 (+)
G111197 NA other downstream 1010265 13011184 ~ 13043448 (+)
AMCG00006672 NA other downstream 1932747 13933666 ~ 13939475 (+)
AMCG00006811 NA other downstream 8936578 20937497 ~ 20944977 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000322_00114516_00119522 TBK1 coding CI01000322 null 114516 ~ 119522 (+)