XLOC_006010 (fancl)


Basic Information

Item Value
gene id XLOC_006010
gene name fancl
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 26703897 ~ 26780797 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00011863
GGGAAGTTACTTTCGCTTTGCTAGGTTCACAGCGGAAGAAGATTATTACAGCAGCGATTGACTGTTTTCCGCAACAACAACAAACAGCACGCTTTTGTCGGTGTTTTTTTAGTTTGATGTCTAGTACTATCGAATGCCGTTTCAGGTACTTGGTTAGCGGTATTTATATTCACGTTGTGGTTTGCCATAATTCTTGTTCATCATGAGCTGCTTGCTGATGAGAGACAGCCCTTTGATCATTGCGCTAAATAAAGAGAAGACGCTCTATGACGGCTTCATCACAGTGCTGATTGCATTGTTGTTGGCAAATGAAGCGGCTACTTCATGGTTATCAACATATTGTGAAGCAGagattACAGCATTCAACTACTTTGATGGCTTTTATCCTGGAGCTCAGGACAGTATTGGAAGTGGCATTGAAGAGCCAACCAGGATGTCAGTCCTTCTCACCACCTCAGTATTATTCGCAGCTGATAACAGAGATGGAGATCTTGGGATGGGATAAACTGCTTTTCATTGATGCAGAGTTTCGCACACTCCAGCTGAAGGCAGAGGACTCTGCAGGTCGTC
>TCONS_00011864
TTCACAGCGGAAGAAGATTATTACAGCAGCGATTGACTGTTTTCCGCAACAACAACAAACAGCACGCTTTTGTCGGTGTTTTTTTAGTTTGATGTCTAGTACTATCGAATGCCGTTTCAGGTACTTGGTTAGCGGTATTTATATTCACGTTGTGGTTTGCCATAATTCTTGTTCATCATGAGCTGCTTGCTGATGAGAGACAGCCCTTTGATCATTGCGCTAAATAAAGAGAAGACGCTCTATGACGGCTTCATCACAGTGCTGGAAAAAGACTTCAGGATAAGAATATCTCTACCCCCTGATCATCAGATGAAACGAGCAAAATTGCATTGTTGTTGGCAAATGAAGCGGCTACTTCATGGTTATCAACATATTGTGAAGCAGagattACAGCATTCAACTACTTTGATGGCTTTTATCCTGGAGCTCAGGACAGTATTGGAAGTGGCATTGAAGAGCCAACCAGGATGTCAGTCCTTCTCACCACCTCAGTATTATTCGCAGCTGATAACAGAGATGGAGATCTTGGGATGGGATAAACTGCTTTTCATTGATGCAGAGTTTCGCACACTCCAGCTGAAGGCAGAGGACTCTGCAGGTCGTCAGCATGCCATTACTGTAAAACTCAAGTCCAAGTATCCAGCTGAGGCTCCAGAGTTTTCTGCGGATCTTCCAATTCCTCTGGTCATCACGTGGACCTCTCAGAGCACCTTGGCCAACGTCCACAGCCAGTTCCTGTTAAACGTTGAGGCTCTGTCTGACTTTTGGTCAGTGCTGGATGAGATCGATGAGAAGACATGGGTGCTGGAACCAGAAAAGCCCACAAAAGCAGACTCCACCAGAAGAATCGCCATTGGAAACAATGTCTCAATAAAGGTACAAATTGACCCCAGACACCCCAAAATGCTGCCGGAGTGCTGTTTGCTCGGGGCTGAGCACGTGGTCACTCCTTTAAGGAATAAGTTGAATGCCAATATGCATTTATGGAACCCTGACTGCACTGTCCTACAGAATATGAAAGATGTGTTGGAGATTGAATTTCCATCGCCTACCACCCACGAAAAATCTAGTTTCAGTGTTGAATGTGGAATCTGCTATTCTTATCGACTTGAGTCAGCCATTCCAGATCAGGTCTGCAATGACCCACGTTGTGGCCAGCCTTTCCATCAAGTGTGTCTTTATGAGTGGCTGAGAGGTCTGCCAACCAGTCGCCAAAGCTTCAATATTGTGTTTGGAGAATGTCCTTACTGCAGCAAGcCCATCACTGTGAAAATGGTCACAGGAAATGCTTAACAACAGTCTGTTCATTCAGAGTAGCGTTGTGTGGCATTACGGCTCCAGCGAGGATAAAACCAACAACCAACAGCTGCTAATATCAGAACAACCAGGAAAGTCAATAGTCTTTTGAATGACCATTTACTCTGATTTATCGATTTTCCGAATCCACTTCCTCTTCTGTGATTCCGTTTAACTTTCAGTTCACATACATCACTTCCCCAGTGGTCTTCATCCTCATCATCAGTTTCGTCCCATTGTGTTTTCTCCCAGGTGTGTTTGTTAGTACAACTCCTCCAGTAGTCAGCTTTACTGCTGGCTACTGCATAGTTGTCATCAATTGATCGAGTACTGTTTTGTTGGTTGTCATACTGGTGGTTTTGTCTCCTGTTGGTCATCCAGGTCTTGCCCTCATAAACATCttcattctttttttcctgtGTTGTTAAAGTAAGTTAGTTTTTTCCCACACAGTATGAGGGCTTAATGTGTTAATACACTATTGTTTCAAACGATAAACACTGCATACTACATACATCTGAGCCAGAATCCATCATTTTCTGCATTGTTtactatattttttgttatatttttaaatcttttatgttgattgtaaagtgctttgagcaTAGAAAAagctctaaataaataaaacgtattCATTAAACTA
>TCONS_00011865
TATTTATTGGTAAACCGACTGTCATGAGCGCCTTATTGTTGATATTAAATCTTTAATAGGAAAAAGACTTCAGGATAAGAATATCTCTACCCCCTGATCATCAGATGAAACGAGCAAAATTGCATTGTTGTTGGCAAATGAAGCGGCTACTTCATGGTTATCAACATATTGTGAAGCAGagattACAGCATTCAACTACTTTGATGGCTTTTATCCTGGAGCTCAGGACAGTATTGGAAGTGGCATTGAAGAGCCAACCAGGATGTCAGTCCTTCTCACCACCTCAGTATTATTCGCAGCTGATAACAGAGATGGAGATCTTGGGATGGGATAAACTGCTTTTCATTGATGCAGAGTTTCGCACACTCCAGCTGAAGGCAGAGGACTCTGCAGGTCGTCAGCATGCCATTACTGTAAAACTCAAGTCCAAGTATCCAGCTGAGGCTCCAGAGTTTTCTGCGGATCTTCCAATTCCTCTGGTCATCACGTGGACCTCTCAGAGCACCTTGGCCAACGTCCACAGCCAGTTCCTGTTAAACGTTGAGGCTCTGTCTGACTTTTGGTCAGTGCTGGATGAGATCGATGAGAAGACATGGGTGCTGGAACCAGAAAAGCCCACAAAAGCAGACTCCACCAGAAGAATCGCCATTGGAAACAATGTCTCAATAAAGGTACAAATTGACCCCAGACACCCCAAAATGCTGCCGGAGTGCTG

Function

symbol description
fancl Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within oocyte development. Predicted to be part of Fanconi anaemia nuclear complex. Predicted to be active in nucleus. Is expressed in central nervous system; eye; heart; intermediate cell mass of mesoderm; and reproductive system. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group L. Orthologous to human FANCL (FA complementation group L).

GO:

id name namespace
GO:0036297 interstrand cross-link repair biological_process
GO:0048599 oocyte development biological_process
GO:0006513 protein monoubiquitination biological_process
GO:0006281 DNA repair biological_process
GO:0005634 nucleus cellular_component
GO:0043240 Fanconi anaemia nuclear complex cellular_component
GO:0046872 metal ion binding molecular_function
GO:0004842 ubiquitin-protein transferase activity molecular_function
GO:0061630 ubiquitin protein ligase activity molecular_function

KEGG:

id description
ko04120 Ubiquitin mediated proteolysis
ko03460 Fanconi anemia pathway
ko04121 Ubiquitin system
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-040426-1045 Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within oocyte development. Predicted to be part of Fanconi anaemia nuclear complex. Predicted to be active in nucleus. Is expressed in central nervous system; eye; heart; intermediate cell mass of mesoderm; and reproductive system. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group L. Orthologous to human FANCL (FA complementation group L).

Ensembl:

ensembl_id ENSDARG00000007885

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00011863 False 570 processed_transcript 0.44 5 26703897 26709399
TCONS_00011864 False 1945 mRNA 0.43 14 26703922 26780797
TCONS_00011865 True 715 processed_transcript 0.45 8 26704273 26772366

Neighbor

gene id symbol gene type direction distance location
XLOC_006009 NA coding upstream 638633 26056457 ~ 26065264 (+)
XLOC_006008 NA coding upstream 720532 25965727 ~ 25983365 (+)
XLOC_006007 NA coding upstream 742528 25944279 ~ 25961369 (+)
XLOC_006006 bcl11aa coding upstream 778673 25846528 ~ 25925224 (+)
XLOC_006005 NA coding upstream 921086 25769999 ~ 25782811 (+)
XLOC_006011 NA coding downstream 21697 26802494 ~ 26809319 (+)
XLOC_006012 soul2 coding downstream 260090 27040887 ~ 27043334 (+)
XLOC_006013 slc24a3 coding downstream 293104 27073901 ~ 27210001 (+)
XLOC_006014 BX323884.1 coding downstream 435844 27216641 ~ 27232573 (+)
XLOC_006015 rin2 coding downstream 451897 27232694 ~ 27296949 (+)
XLOC_005997 BX530079.1 non-coding upstream 1259374 25443984 ~ 25444523 (+)
XLOC_006019 CR354610.2 non-coding downstream 583152 27363949 ~ 27391937 (+)
XLOC_006021 NA non-coding downstream 1004297 27785094 ~ 27805880 (+)
XLOC_006022 dre-mir-30e-2 non-coding downstream 1014333 27795130 ~ 27795209 (+)

Expression


Co-expression Network