AMCG00007813 (idh2,LOC107714782,LOC107691122,LOC107715227)


Basic Information

Item Value
gene id AMCG00007813
gene name idh2,LOC107714782,LOC107691122,LOC107715227
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030123.1
NCBI id CM030123.1
chromosome length 53548854
location 31111645 ~ 31136247 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00007813
CGCCGCCAGTGCGCAGCCTCAGCAGCGGAGCGGCGCCGCACAGGTAGCGACGCACTGAGCTGTTGAGCTGCTGCTCGTAGCGATTCGACCCCATCTCTTCAGCGCTGCTCGCCCGGTTCAATTGTGCACAATGACATGTGTTGCTCTTTGGATGCTGCTGCTCAGCCTTGTTTTAGTTTCCAGCACTGAGCTGACGTTTGAATTACCCGATAATGACAAACAGTGCTTCTACGAAGAACTTGAAAAAGGAGTCAAGTTTAACATCGATTATcaaGTTATTGCTGGAGGCAACTATGATGTTGACTGCTTTGTGACGGATGCAGTGGATAATGTCCTGTATCACGAAAAGAAGAAGCAGTATGACAGCTTCACTCACATCACAGAAACGAAAGGTGTTTACAAGGTCTGCTTCAGCAACGAGTTCTCCACCTTCTCCCACAAGATTGTATACCTCGACTTCCGAAGTGGAGACGAGCGACCTCTCCTCCCCGACATGAACAGAGCCACGGCCTTAACCCAGATGGAGTCGGCTTGCCTTTCCCTCCACGAAATTCTCAAGACAATGTCGGACTCTCAGACCTGGTACCGGCTCAGGGAGGCCCAGGACCGGCTCCGCGCTGAGGAGATCCACGACCGCGTGTCCTATTGGTCCATGGGAGAGACCTTCATCCTCTTCGTGGTCAGCATCGGCCAGGTGGTCATGCTCAAGAGCTTCTTTACAGACAAGAAAGCCAGCGTGGCCAGCAGCACGTAGACATTGCCATGGCAGGTCCGCTCTTCTGACTTGCACTTGAGGCATAGCAGGAGGGGAAAGGCtagggtaaaaaataaaataaaataaatcagtagtACTTCTGTCACCCAGGGCCCACAGGTCAATGTGTCTCTGTTTCCTCAGTTAGATAATCAGTCCGTGCAGTTTGTAATGAATTAACTACAAAGATCCACTCAGGCTCTCGGTGACCAGAGTTGTGTAGCACACATGTTGTGATCccatcaaaaacattttttttaaagcttgtcAAACAGTGACTATAACTTGGCTATTGTAGCATTTCTTTACTGAAGAGTGCgcgtgcatgcgtgtgcgtgcgttTCTTTACCAAAAGACATCCCTTCCACTTTACAGCTACGCAATTATTTATGCCTCAATTCATTTTACTTGCTATATTCTTGATGTCTCTTTTGTACTTCACAGACTTTGATAAACAATCTGAGACACTAATCTGCCTATATCTGCCTTTGttgtcaatgtttttatgttgtaaaaGTAGAGAACCATGTCCCTGGTATGTTTACAAAGATACATTCTTATAAGAAGGGACAAATTACAATGCCAAAAACATCTTTCAAAACTTGAATGAGCATTTAATTGTGATTTGCCACATTACAAAACAATCCTGCTGTTGTTAGGTCACCTACCCACTGATTACAAGTTCAGTTCCTAAGTTAGTGTTGATTCCATATTTTCAGTAATAAGGGAACCAAAATATTGTGCTTTGTATGATTTCCAGTGTCTTTTGTTTACTGCCTTTGAATAGTGTTACATatctcagttttctttttctctttagtGTTTACTGATAAGAGACAAGGGTGAAGTTTTGTCTgtagatgttatttttaaataattagtaCTCCCTACCAATCCTCCCAACCACTGGGATCATGAAgaaatacaactatttaaaatgGGGGGCTCCTCCTGGCTTTTATAAGACTAAGATACTTGGTAATGTGTAGTTTGGAAAAACTggttttatttcacacacacacccacacactgagAGTGTAGTTGGTTATTTGTCAAACTGCtgattttaagatgttttaccCAGAAGGAAAGCTGTAGTACCCTGTTGTTCATGTAGAATACACAAGAGCGCATGGAGGTAATGGTTGAGTCATTGCACAATGGAAAtggtagaaaaacaacaaccaaaaaacacactttttgtttCTGGTCACTCTGTTGCAATGAGGGTGTTGGTCCACTGAGTGGGGGTGTTCAAACCCATCTGCCTTTCACATTCATTACAAAATGGGACCTATGCACATAGACAGCATTTCCCATTACTCTGTGTATACCACACTTTAAAGCAGGTTTAAGTAATCAAATCTTACCTtttcaaaattgtttattttacttcgCTTGAATAGGAGTATGTTTGTTGCCTTTGTTAACGCTCCTGCTCGGTCATTTGTTTCCTGcggtgtgtgttttctgtgctcaGTGCTTGTTAGAGGTGTAGGGGGGTAGGGGTGGGGTGTCTGAATCTTTAGGAAGCTGAaggattcttttttttcttctaaaaagaCAACTACCTTTCCACTTACTTGACCTTACCTGTTGGATTTCCTGCTGGGTCAGCACTTACCGGGCAGACGAAAAATAAAGTACCATAATCCATTGCGCAGCGGCAACCCTCTCTCCTTACAGACGGTGACGTGGGCCGGAGTCTGAGATGGGGAGGCGCTCCGCTGTTATATCGCACGGAGCGGCAGTCCCGCTCGGCCTTTCTTCGTCCGGAGTGTAACCGTTTCACAGTAGCAGCTGCAAGGGCAACCGTGAACCATGGCAGGGTACCTCAAGGTCCTCAGCTCCCTCTCCAGATCCGCCACCGCACTGGCGAAAAACCCCGCCGTGCTGGCCCCCGCAGCCGGACACAGCCCGCAGCAGAGGAACTTGGTGAGCCGGGGAGAGCCGGTGAAAGCCGGTGCCAATGAGGAGGGCCGGGCGACCATCTTGCACGAAAAAAGCCGGCTGGCGCTGAAACGCTTCTGTATGAATGGGAAACGCACAGCAGCGCGGGATGACTCACCCAATGCTGACAAGCGTATCAAGGTGGCCCAGCCTGTGGTGGAAATGGACGGTGATGAGATGACTCGTATCATCTGGGAGTTCATCAAGGAGAAGCTCATTTTGTCCAACGTGGATGTGGAGCTGAAGTATTTTGACCTGGGTCTTCCGTACCGTGACCAGACGAATGACCAAGTCACCATCGACTCTGCTATTGCAACCCAGAAGTACAGTGTTGCTGTTAAATGTGCCACCATCACTCCCGATGAGGCCAGAGTTGAAGAGTTCAATCTGAAGAAGATGTGGAAGAGCCCCAATGGAACCATCAGGAACATCCTGGGCGGGACAGTCTTCCGTGAGCCAATTATCTGCAAGAACATTCCCCGTCTTGTCCCTGGTTGGACGCAGGCCATCACCATTGGCCGTCATGCGTTCGGTGACCAGtACAAAGCAACAGACTTTGTGGTGAGCAAACCAGGAAAATTCAAGATGGTGTTCACTCCCACAGACGGGACCAAGGCCTCCGAGTGGGAGGTGTACAACTTCCCTGGGGGTGGCTGCGGAATGGGCATGTACAACACGGATGAGTCCATCTCTGGGTTTGCTCACAGCTGCTTCCAGTACGCCATCCAGAAGAAGTGGCCCCTGTACATGAGCACCAAGAACACCATCCTGAAGGCATACGATGGGCGCTTCAAGGACATCTTCCAGGAAATCTTTGAGAAGAACTACAAGCCTGAGTTTGACAAGCTGAAGATCTGGTACGAGCACCGGCTCATTGATGACATGGTGGCTCAGGTGCTGAAGTCCTCGGGTGGCTTTGTTTGGGCCTGCAAGAACTACGATGGGGATGTGCAGTCTGACATCCTGGCTCAGGGCTTCGGCTCCCTGGGACTGATGACTTCCGTGCTGGTGTGCCCTGATGGTAAGACCATCGAGGCGGAGGCAGCCCACGGCACTGTCACCCGGCACTACCGTGAGCACCAGAAGGGCCGGTCAACAAGCACCAACCCCATTGCCAGTATTTTTGCCTGGACCAAGGGACTGGAGCACCGTGGAAAGCTTGACGGCAACCCCGATTTGATCAGGTTCTCGCAGACACTGGAGCGTGTGTGCGTCGAGACGGTGGAAAGTGGAGTCATGACCAAGGACCTCGCTGGCTGCATCCATGGCCTTGCAAACTGTAAACTGAACGAGCACTATGTGAACACTACAGACTTCCTCGATGCAATCAAGAATAACCTGGACAGAGCCCTGGGCAAGTGAGAAACATCAAGACAAGATGCTGGAAAATTAAGTTTTctattggttttgtttgtttttttacctcatttttaacttttaaaaggTCATGATGATAACCACAAACATCTTGATTTGAAGGGTAaaaattttagtattttaatatagAAGTTTCTGTACAGACTGACTTAGTGTACAGTTTCAATGTATTGTACTGTCGACTTACTCCACTCCCTCATACCTTGTCCAAGGTCCTGCTTTTGTAATGTGAAGTACACCTcagatttgtaatttatatacCATGAAACAACTTGATAAATGGCCATTGCAAGCAATATATATTTCCCTAATAAAACTCAGTACCTTGTTGTAA

Function

symbol description
idh2 Predicted to enable NAD binding activity; isocitrate dehydrogenase (NADP+) activity; and magnesium ion binding activity. Predicted to act upstream of or within glyoxylate cycle; isocitrate metabolic process; and tricarboxylic acid cycle. Is expressed in several structures, including blastoderm; brain; digestive system; pectoral fin bud; and renal system. Human ortholog(s) of this gene implicated in D-2-hydroxyglutaric aciduria 2; acute myeloid leukemia; hepatocellular clear cell carcinoma; intrahepatic cholangiocarcinoma; and lung cancer. Orthologous to human IDH2 (isocitrate dehydrogenase (NADP(+)) 2).

NR:

description
PREDICTED: isocitrate dehydrogenase [NADP], mitochondrial

GO:

id name namespace
GO:0006099 tricarboxylic acid cycle biological_process
GO:0006102 isocitrate metabolic process biological_process
GO:0051287 NAD binding molecular_function
GO:0004450 isocitrate dehydrogenase (NADP+) activity molecular_function
GO:0000287 magnesium ion binding molecular_function

KEGG:

id description
K00031 IDH1, IDH2, icd; isocitrate dehydrogenase

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00007813 True 4415 mRNA 0.47 15 31111645 31136247

Neighbor

gene id symbol gene type direction distance location
AMCG00007816 NA coding upstream 13288 31096738 ~ 31098357 (+)
AMCG00007808 rps27,LOC104929087,LOC106605899,LOC108429942,LOC107084035,LOC100696027 coding upstream 167918 30941199 ~ 30943727 (+)
AMCG00007809 LOC107674425 coding upstream 196180 30882916 ~ 30915465 (+)
AMCG00007805 otud7a,LOC107715690,LOC107659507,LOC107550219,LOC107752330,LOC107698115,LOC107598848,LOC108275340 coding upstream 337184 30731611 ~ 30774461 (+)
AMCG00007806 gtf2a2 coding upstream 498453 30610218 ~ 30613192 (+)
AMCG00007818 LOC106573467,LOC106561177 coding downstream 134428 31270675 ~ 31302984 (+)
AMCG00007820 NA coding downstream 168789 31305036 ~ 31317396 (+)
AMCG00007819 NA coding downstream 188835 31325082 ~ 31339183 (+)
AMCG00007825 NA coding downstream 359692 31495939 ~ 31497811 (+)
AMCG00007826 NA coding downstream 372424 31508671 ~ 31509949 (+)
G26463 NA non-coding upstream 4396 31106714 ~ 31107249 (+)
G26462 NA non-coding upstream 5021 31106414 ~ 31106624 (+)
G26461 NA non-coding upstream 5624 31103954 ~ 31106021 (+)
G26458 NA non-coding upstream 11129 31100271 ~ 31100516 (+)
G26433 NA non-coding upstream 155752 30955638 ~ 30955893 (+)
G26483 NA non-coding downstream 81863 31218110 ~ 31218322 (+)
G26625 NA non-coding downstream 645391 31781638 ~ 31781891 (+)
G26645 NA non-coding downstream 686493 31822740 ~ 31822973 (+)
G26698 NA non-coding downstream 1486013 32622260 ~ 32622530 (+)
G26704 NA non-coding downstream 1751543 32887790 ~ 32888040 (+)
G26258 tpm1,tpma,LOC108237348 other upstream 1292093 29755040 ~ 29819552 (+)
AMCG00007788 NA other upstream 1386911 29622311 ~ 29724734 (+)
AMCG00007769 acsbg1 other upstream 2105266 29003095 ~ 29006379 (+)
AMCG00007763 tbc1d2b other upstream 2200079 28900058 ~ 28911566 (+)
AMCG00007754 NA other upstream 2411583 28682171 ~ 28700062 (+)
AMCG00007827 ell3,LOC103370942,LOC102298519,LOC102798071,LOC108431223,LOC107714787 other downstream 277907 31414154 ~ 31440378 (+)
AMCG00007854 NA other downstream 2627266 33763513 ~ 33794941 (+)
AMCG00007873 fam174b,LOC103466638,LOC101474125,LOC102798031,LOC103147863 other downstream 4474735 35610982 ~ 35620801 (+)
AMCG00007889 NA other downstream 5159971 36296218 ~ 36302841 (+)
AMCG00007923 LOC105031092,LOC105901836,LOC102299656,LOC101482251 other downstream 6067623 37203870 ~ 37216558 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_013453 idh2 coding NC_007129.7 CM002902.2 26096814 ~ 26101800 (-)
grasscarp (Ctenopharyngodon idella) CI01000013_00862608_00869073 IDH2, IDHP, IDH2.S coding CI01000013 null 862418 ~ 869073 (+)