AMCG00011023 (lck,LOC100136288,LOC100136287)


Basic Information

Item Value
gene id AMCG00011023
gene name lck,LOC100136288,LOC100136287
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030133.1
NCBI id CM030133.1
chromosome length 32682731
location 7997538 ~ 8026488 (-)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00011023
CTGGTATGTCGGGAAACTAAAGaccttttcttttattgttttgttttttcactccaAGGATCAAGTTGGGATTCGCTTAAgttattatttgcttttttacatttattgattgattgattgatttctcaTCAAGGATCTCGACAGGCACACAATGCTCATTGCCGCTGTGGGACAGAGTGTCCTGTGCAGGGGTCAATAGAATGTAGAGGTCTTCTCCAGAAAGGCTTCAGAATTATCAGAAAAGATGGGCTGCAACTGCAGTTCAGAATATGACGATGACTGGATCGAGAACTTGGATGAAGTCTGTGAACACTGTAACTGCCCTCTGCCACCACAGAGCAAGAACCAGTACACAGATGCACCAGGCCCCCTGATTCCCTATTCGTCACACACCCCGCCCTCGTCACCCTTGCCTGATAACTTAGTCATCGCATTGTACAGCTATGAACCCAATCACAGCGAAGACCTGGGAtttgaaaaaggagaaaaactgaaaatcctGAACGCGGATGACAATGAGTGGTACATGGCTCAGTCCCTGGCGACAGCGAAGACCGGCTACATTCCCTACAACTTCATTGCCAAGCTGGACACCATAGAGACTGAACCGTGGTATTTTAAAGACATCTCTCGTAACGATGCCATGAGGCAACTCCTCGCACCAGGAAACACGCAGGGCTCCTTCCTCATCAGAGAGAGTGAAACTGCCAAAGGGTCTTTCTCCTTGTCTGTGAGAGACTTGGACCCAGACAGTGGAGATACTGTAAAGCACTACAAGATTCGCAATCTGGATAATGGAGGCTTCTACATCACACCCAGAATCTCATTCAGCACCATGTCAGACCTTGTTAAGCATTACTCCAGAGAGTCGGACGGCTTGTGCACACGTCTCTCCAAGCCATGTCAGACCCGCATGCCCCAGAAGCCATGGTGGCAGGACGAGTGGGAGATCCCAAGGGAGTCTCTGAAGCTGGAGCGCAGACTTGGGGCCGGCCAGTTTGGAGAGGTCTGGATGGGTCTGTACAACAACAATCGTAAGGTGGCCATTAAAAACCTGAAGGCCGGCACCATGTCCACCGCTGCCTTCCTAGCTGAGGCCAACCTGATGAAGAACCTGCAGCACCCCCGCCTGGTGCGCCTGCATGCCGTGGTCACACAGGATCCTATCTACATCATCACCGAGTTCATGGAGAATGGGTGCCTTGTTGATTTCCTGAAAACGCCCGAGGGAGCCAACCTGACAATCAACATACTCATAGACATGGCAGCACAGGTGGCAGAGGGCATGGCATTCATCGAGCAGAAGAACTACATCCACAGAGACCTGAGAGCCGCCAACATCCTGGTCTCTGAGGAGCTGACCTGCAAGATAGCGGACTTCGGACTGGCCAGACTTATTGAAGACAATGAGTACACAGCCAGGGAAGGTGCTAAGTTCCCAATCAAATGGACGGCCCCCGAAGCCATTAACTATGGGACCTTCTCTATCAAGTCAGATGTGTGGTCTTTTGGAATCCTTCTGACTGAGATAGTGACATACGGACGCATACCCTATCCAGGAATGACCAACCCTGAAGTCATCCAGAACCTGGAGCGTGGCTACAGGATGCCACGGCCCGACAACTGTCCTGAGGAGCTGTACAGTGTGATGCAACGCTGCTGGAAGGAGACCCCCGAGGAGCGGCCCACCTTTGAGTACCTGAAGAGCGTGCTGGAGGATTTCTTCACTGCCACAGAGGCCCAGTATCAGCAACAGCCCAGCTGAAATACGCTGTGGCACACACAATAACTCCAATAACACAAACATCTCacctgaaactgaaaaccatGCAGCAGTTGTTTCTCTttacttcttcctctccttcttttttgttgttttttggggatAAATGAGAAACTAACACTCCAAAAGGTGTTTCTTATTCTTATCTGCTTTCTATAGGTTTTCCATATGTTTTATAATGcacaggttttattattttacaactattattaaaatcaggagttccttttctttttcttttttaacactCAGCAGAACAGATAGATTTTTTCATTCACCTCAACTGCCATTCACACCTTCCTGCGTCAGTGAAGATACTTTGTATTCAATTTCCCAATTTCAACAGCCCTTTGAAAGACTTTAGGgacttcaatatatatatattgaagtccctaaagtttttttattgtattacttttcattttaattttcatttataataataaatatatgatatTAACTTGTTGGAATTATACAGATGTTTTATGGTCTAGCTTTTTTATATTGTGTGCAGAATGGCTATTATCTTTGTAATCCGATTA

Function

symbol description
lck Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in T cell differentiation; cell surface receptor signaling pathway; and innate immune response. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytosol. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in T cell; head kidney; lymphocyte; pro-T cell; and thymus. Human ortholog(s) of this gene implicated in immunodeficiency 22. Orthologous to human LCK (LCK proto-oncogene, Src family tyrosine kinase).

NR:

description
LCK2

GO:

id name namespace
GO:0018108 peptidyl-tyrosine phosphorylation biological_process
GO:0005524 ATP binding molecular_function
GO:0004713 protein tyrosine kinase activity molecular_function

KEGG:

id description
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00011023 True 2325 mRNA 0.46 13 7997538 8026488

Neighbor

gene id symbol gene type direction distance location
AMCG00011022 hdac1 coding downstream 2919 7985281 ~ 7994619 (-)
AMCG00011013 NA coding downstream 254972 7733423 ~ 7742566 (-)
AMCG00011012 fndc5b,fndc5 coding downstream 350526 7632065 ~ 7647012 (-)
AMCG00011008 NA coding downstream 445923 7529457 ~ 7551615 (-)
AMCG00011009 NA coding downstream 490372 7451069 ~ 7507166 (-)
AMCG00011021 LOC101067225 coding upstream 4689 8031177 ~ 8037256 (-)
AMCG00011029 eif3i,LOC102790120 coding upstream 34955 8061443 ~ 8065757 (-)
AMCG00011028 NA coding upstream 44358 8070846 ~ 8077484 (-)
AMCG00011026 NA coding upstream 51890 8078378 ~ 8080975 (-)
AMCG00011024 ccdc28b,LOC103357048,LOC102215669,LOC106535222 coding upstream 55930 8082418 ~ 8090075 (-)
G103794 NA non-coding downstream 217597 7777008 ~ 7779941 (-)
G103666 NA non-coding downstream 764224 7230954 ~ 7233314 (-)
G103658 NA non-coding downstream 807955 7189085 ~ 7189583 (-)
G103645 NA non-coding downstream 825733 7115984 ~ 7171805 (-)
G103556 NA non-coding downstream 1235399 6755293 ~ 6762139 (-)
G103859 NA non-coding upstream 29993 8056481 ~ 8056683 (-)
G103893 NA non-coding upstream 141207 8167695 ~ 8167924 (-)
G103900 NA non-coding upstream 314875 8341363 ~ 8341588 (-)
G103903 NA non-coding upstream 316096 8342584 ~ 8342818 (-)
G103929 NA non-coding upstream 434442 8460930 ~ 8462662 (-)
AMCG00010988 NA other downstream 1352815 6628570 ~ 6644723 (-)
AMCG00010966 NA other downstream 2023231 5965133 ~ 5974307 (-)
G103395 NA other downstream 2248974 5704770 ~ 5748564 (-)
AMCG00010946 NA other downstream 2672114 5284330 ~ 5325424 (-)
AMCG00010939 NA other downstream 2857029 5134053 ~ 5140509 (-)
AMCG00011051 NA other upstream 793063 8819551 ~ 8864051 (-)
AMCG00011058 srrm1,LOC107583602,LOC107721297,LOC106579139 other upstream 1195780 9222268 ~ 9236228 (-)
AMCG00011084 dlgap3,LOC106933674,LOC106958363 other upstream 1574889 9601377 ~ 9619279 (-)
AMCG00011086 NA other upstream 1714645 9741133 ~ 9743785 (-)
AMCG00011125 eef1a1l2,LOC107589444,LOC107706209,LOC107654701,LOC100136525,LOC105027913 other upstream 3932750 11959238 ~ 11971002 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_012128 lck coding NC_007128.7 CM002901.2 25344734 ~ 25382376 (-)
grasscarp (Ctenopharyngodon idella) CI01000312_00286629_00287654 LCK coding CI01000312 null 286629 ~ 287654 (+)