AMCG00012688 (ascl1a,ascl1,LOC107590149,LOC107664850,LOC107596391,LOC107744950)


Basic Information

Item Value
gene id AMCG00012688
gene name ascl1a,ascl1,LOC107590149,LOC107664850,LOC107596391,LOC107744950
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030125.1
NCBI id CM030125.1
chromosome length 49972098
location 4507627 ~ 4508220 (-)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00012688
ATGGATATCACTGCCAAGATGGAAATAAGCACCAGCCAGCAGCAGTTCATGCCGCCTGCCTGTTTCTTTGCGGCTGCCGCCCAGAATATCCAGCTCAGCCCCACTGACAGCCAGTGCAGCAGTAAATCAGGCAAGCAGGTCAAAAGACAGCGTTCGTCCTCGCCCGAGCTGCTAAGGTGCAAAAGGAGGCTGAACTTCGCTGGCTTTGGGTACAGCCTGCCCCAGCAGCAGCCCGCGGCGGTGGCCCGGCGCAACGAGAGGGAGAGGAACAGGGTGAAGCTGGTCAACATGGGCTTCGCCACGCTGCGGGAGCACGTCCCCAACGGCGCCGCAAACAAGAAGATGAGCAAGGTGGAGACCCTGCGCTCGGCGGTGGAGTACATCCGGGCgctgcagcagctcctggaCGAACATGACGCCGTGACCGCTGCCTTCCAGTCGGGGGTCCTCTCTCCGACCATCTCCCAGAACTATTCCAACGACATGAACTCCATGGCGGGCTCACCTGTCTCCTCGTACTCTTCAGACGAGGGATCTTACGACCCCTTGAGTCCTGAGGAGCAAGAACTCTTGGACTTCACCAATTGGTTCTGA

Function

symbol description
ascl1a Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in hindbrain morphogenesis and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; epithelial cell differentiation; and regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including digestive system; nervous system; neural tube; neuronal stem cell; and optic cup. Human ortholog(s) of this gene implicated in congenital central hypoventilation syndrome. Orthologous to human ASCL1 (achaete-scute family bHLH transcription factor 1).
ascl1 Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; E-box binding activity; and bHLH transcription factor binding activity. Involved in several processes, including neuron differentiation; regulation of transcription by RNA polymerase II; and response to retinoic acid. Located in nucleus. Implicated in congenital central hypoventilation syndrome.

NR:

description
achaete-scute homolog 1a

GO:

id name namespace
GO:0010629 negative regulation of gene expression biological_process
GO:0021575 hindbrain morphogenesis biological_process
GO:0061195 taste bud formation biological_process
GO:0002070 epithelial cell maturation biological_process
GO:0043697 cell dedifferentiation biological_process
GO:0045893 positive regulation of transcription, DNA-templated biological_process
GO:0061549 sympathetic ganglion development biological_process
GO:0070654 sensory epithelium regeneration biological_process
GO:0021984 adenohypophysis development biological_process
GO:0045666 positive regulation of neuron differentiation biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0000989 obsolete transcription factor activity, transcription factor binding molecular_function
GO:0046983 protein dimerization activity molecular_function

KEGG:

id description
K09067 ASCL; achaete-scute complex protein

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00012688 True 594 mRNA 0.60 1 4507627 4508220

Neighbor

gene id symbol gene type direction distance location
AMCG00012684 NA coding downstream 126343 4379873 ~ 4381284 (-)
AMCG00012683 NA coding downstream 140263 4349107 ~ 4367364 (-)
AMCG00012682 NA coding downstream 198907 4303995 ~ 4308720 (-)
AMCG00012678 usf2,LOC105007924 coding downstream 483224 4015172 ~ 4024403 (-)
AMCG00012677 usf2,LOC101066260 coding downstream 517537 3980790 ~ 3990090 (-)
AMCG00012690 NA coding upstream 115695 4623915 ~ 4642672 (-)
AMCG00012691 NA coding upstream 176696 4684916 ~ 4696006 (-)
AMCG00012689 LOC107744925,LOC107664854,LOC107588513,LOC107590206,LOC107695881,LOC107725616 coding upstream 252465 4760685 ~ 4772958 (-)
AMCG00012693 mybpc1 coding upstream 279314 4787534 ~ 4827776 (-)
AMCG00012692 NA coding upstream 332007 4840227 ~ 4846796 (-)
G39017 NA non-coding downstream 177992 4327083 ~ 4329635 (-)
G38910 NA non-coding downstream 410886 4037439 ~ 4096741 (-)
G38909 NA non-coding downstream 531031 3974353 ~ 3976596 (-)
G38842 NA non-coding downstream 723577 3783804 ~ 3784050 (-)
G38841 NA non-coding downstream 724236 3783160 ~ 3783391 (-)
G39160 NA non-coding upstream 277474 4785694 ~ 4786528 (-)
G39174 NA non-coding upstream 405783 4914003 ~ 4916594 (-)
G39175 LOC106613431,LOC106584099,LOC106573797,LOC106609167 non-coding upstream 421568 4929788 ~ 4930753 (-)
G39189 NA non-coding upstream 423024 4931244 ~ 5006607 (-)
G39231 med21,LOC102798687 non-coding upstream 698384 5206604 ~ 5209859 (-)
G38490 NA other downstream 2323464 2183885 ~ 2184163 (-)
AMCG00012646 LOC107658747,LOC107707963 other downstream 2690427 1578955 ~ 1817200 (-)
G38458 NA other downstream 2730406 1776854 ~ 1777221 (-)
AMCG00012628 golt1b,LOC108428784,LOC107676462,LOC107701063 other downstream 3968036 514222 ~ 539591 (-)
AMCG00012732 NA other upstream 1544144 6052364 ~ 6063817 (-)
G39487 NA other upstream 1947501 6455721 ~ 6456178 (-)
AMCG00012751 NA other upstream 2130260 6638480 ~ 6695924 (-)
AMCG00012782 NA other upstream 3383269 7891489 ~ 7904455 (-)
AMCG00012829 NA other upstream 4604221 9112441 ~ 9152405 (-)

Expression


Co-expression Network