AMCG00012929 (lta4h)


Basic Information

Item Value
gene id AMCG00012929
gene name lta4h
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030125.1
NCBI id CM030125.1
chromosome length 49972098
location 14299408 ~ 14313229 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00012929
ATGGCTCCTGTGAACGATCCCAGCTCGTTTTCTGCTCTATCAAAGTGCATCACCAGACACCTGAACCTGCGCTTTCATGTTGACTTTGACAGTCGTGTCATTAAAGGCAAAGTGGCCCTGACTGTAGAAATACTGGAGGACAAATGCGCCAGCCTGattCTTGACACCAAGGACTTGAAGATCAGCAAAGTCACAGCTAATGGGCAGGAGGCCAAGTTTTCCCTGGGACCCCAGCACAGCTTCAAGGGCTCCCCTCTGGAGATCTCCCTGCCTTTTGAATTGTCCCGGGGTCAGCATGTGATCATCGAGGTGACCTACGAGACCTCCCCCAAGGCCTCGGCTCTGCAGTGGCTCACGCCTGAACAGACTGCTGGGAAAAAGCACCCTTATCTCTTCAGTCAATGCCAGGCTACCCACTGTCGGACCATGGTCCCTTGTCAGGATACCCCTTCTGTGAAACACACCTACTATGCGCAGGTGTCGGTCCCTAAGGAATTGGTGGCGCTGATGAGTGCAGTGAGGGATGGGCAGGAGCCAGACCCTCAGGACAGCAGCAGATCTGTGTTCCGCTTCAGGCAACCCGTCCCCATGCCATCTTATTTAATAGCCATAGTGGTTGGTGCACTGGAGAGCAGAGAGATTGGTCCGAGGAGCAGGGTGTGGTCAGAGAAGGAGCTGGTGGATCTGGGTGCCTATGAGTTTGCAGAGACCGAAGCCATGCTGAAGATTGCAGAGGACCTGGCCGGGCCCTATGTTTGGGGTCAGTATGACCTGCTGGttctccctccttccttcccgTATGGAGGCATGGAAAATCCCTGTCTGACATTCGCCACCCCCACGCTGCTGgcAGGTGACCGATCCTTGTCCAATGTCATTGCACATGAGATCTCTCACAGCTGGACTGGCAACCTGGTGACCAACAAAACCTGGGAGCACTTCTGGCTAAACGAGGGCCACACTGTGTACCTTGAGAGAATGATTGGCAGTCGCCTGGTGAAAACCTTCGGAGCCAATAATCCATTGACCAACCTTGTGCCAAACTTGACAGAAGTGGACACGGACGAGGCTTTTTCCTCTGTCCCCTATGAAAAGGGTTTTGCTTTCCTCTACCATCTGGAAGAGCTAATGGGAGGCCCAGAGGTGTTCATGGGATTTGTCAAGTCCTATATTCAGATGTTTGCTTATAGCAGTGCCACCACCGAAGACTGGAAAAACTACCTGTACACCTATTTTAAGGACAAGgTTGATATTCTGAACAAGGTGGACTGGGATGGGTGGATGCACACACCTGGAATGCCACCAGTCAAACCACAGTATGACACCACCTTAGCTGATGCCTGTATTGCCTTGTGTCAGAAATGGATCAAGGCAAAGGAGGCTGATCTGAAGTCTTTCAGTGAAGCGGATATAAAGCAGTTGTCTTCCCACCAAGTGATCGAGTTCCTGGCTCTCTTGCTGCTGGAGAACCCGATCCCATTGTCACACGTCAAAAGAATGCAGGAGGTCTACAATTTGAATGCCATTAAAAACTCTGAAATAAAACTCAGGCaaTGGGAGGAAGCCGTCCCATTGGCTCTCAAAATGGCCACTGAGCAAGGGCGCATGAAGTTCACACGCCCACTGTTCAGgGAGGTGTACAACTTTGAGAAGTACCGTGAGGAGGCAGTCAACACCTTTCTCAAACACAAGTCTGGCATGCACCCAGTCACAGCCATGCTCACTGCAAAGGATCTGAAGCTGGACCAAGCCAAGAGCACTGGGCTCTAG

Function

symbol description
lta4h Predicted to enable aminopeptidase activity; epoxide hydrolase activity; and leukotriene-A4 hydrolase activity. Acts upstream of or within several processes, including epiboly involved in gastrulation with mouth forming second; neutrophil chemotaxis; and response to bacterium. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Is expressed in intestinal bulb; macrophage; and neutrophil. Orthologous to human LTA4H (leukotriene A4 hydrolase).

NR:

description
novel protein (zgc:85809), partial

GO:

id name namespace
GO:0006954 inflammatory response biological_process
GO:0019370 leukotriene biosynthetic process biological_process
GO:0006508 proteolysis biological_process
GO:0004463 leukotriene-A4 hydrolase activity molecular_function
GO:0008237 metallopeptidase activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K01254 LTA4H; leukotriene-A4 hydrolase

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00012929 True 1770 mRNA 0.52 19 14299408 14313229

Neighbor

gene id symbol gene type direction distance location
AMCG00012926 cdk17,LOC107658862,LOC107656329 coding upstream 40245 14228638 ~ 14259163 (+)
AMCG00012922 NA coding upstream 123785 14163667 ~ 14175623 (+)
AMCG00012923 NA coding upstream 146547 14146487 ~ 14152861 (+)
AMCG00012921 camk1d coding upstream 196682 14078324 ~ 14102726 (+)
AMCG00012920 NA coding upstream 237495 14042259 ~ 14061913 (+)
AMCG00012930 hal,LOC103041200,LOC107670217,LOC107740873,LOC108275357,LOC102785645 coding downstream 2612 14315841 ~ 14324873 (+)
AMCG00012928 NA coding downstream 19553 14332782 ~ 14340902 (+)
AMCG00012934 NA coding downstream 52869 14366098 ~ 14395069 (+)
AMCG00012935 NA coding downstream 92329 14405558 ~ 14419258 (+)
AMCG00012936 NA coding downstream 120574 14433803 ~ 14451103 (+)
G40920 NA non-coding upstream 113272 14185240 ~ 14186136 (+)
G40846 NA non-coding upstream 311320 13986950 ~ 13988088 (+)
G40824 NA non-coding upstream 414219 13883261 ~ 13885189 (+)
G40788 LOC107575789 non-coding upstream 1038229 13260644 ~ 13261179 (+)
G40777 NA non-coding upstream 1183876 13115312 ~ 13115532 (+)
G40963 NA non-coding downstream 27717 14340946 ~ 14344481 (+)
G40986 NA non-coding downstream 82347 14395576 ~ 14395899 (+)
G40989 NA non-coding downstream 84368 14397597 ~ 14397855 (+)
G41054 NA non-coding downstream 312023 14625252 ~ 14625850 (+)
G41058 NA non-coding downstream 315354 14628583 ~ 14630610 (+)
G40629 NA other upstream 1763479 12488575 ~ 12535929 (+)
AMCG00012894 gdi2,LOC107585127,LOC107560733,LOC107754057,LOC107694307,LOC107757239 other upstream 1799006 12453239 ~ 12500402 (+)
AMCG00012848 NA other upstream 3757448 10540728 ~ 10541960 (+)
G40224 NA other upstream 3854961 10436907 ~ 10444447 (+)
AMCG00012820 nt5dc3,LOC102307862,LOC107753643 other upstream 5169197 9112460 ~ 9130211 (+)
G40999 metap2,LOC108428789,LOC100194705 other downstream 115084 14428313 ~ 14433201 (+)
AMCG00012940 LOC107748465 other downstream 203554 14516783 ~ 14529806 (+)
G41059 NA other downstream 319128 14632357 ~ 14633413 (+)
AMCG00012954 NA other downstream 768190 15081419 ~ 15136729 (+)
AMCG00012961 NA other downstream 984733 15297962 ~ 15317344 (+)

Expression


Co-expression Network