AMCG00014441 (grk1,grk1a,LOC107748333)



Basic Information


Item Value
gene id AMCG00014441
gene name grk1,grk1a,LOC107748333
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information


Item Value
chromosome id CM030128.1
NCBI id CM030128.1
chromosome length 42883965
location 13930882 ~ 13939105 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence


>AMCG00014441
ATGGATATAGGGGGTCTGGAGACTGTGGTGGCCAACTCGGCTTACATATCAGCCCGAGCAAGCTTTGATGGCTCCAGCAATGCATCAGCCACCCGGGACAAGAAGTACCGTGCCAAGCTCAAGCTTCCCCACATCACCCAATGTGAGGACCTGACCGAGAAGATCGACTTGGAGTATGACAGCATCTGCAACCAGCAGCCCATTGGCAAGCGTCTCTTCCAGGAGTATCTGGAGACGGTGCCCGAGTACAAGCCTGCCTCTAAAGTGTGGAAGGATATAGAGGAGTATGACACTGCTGAGGACAAGGACCGTGTACAGAAAGCCTCCAAGATCATCTCCAGATACATGGTGTCCACCGCCAAGCACTACTGCTCCTTCCTGCAGGAGAACACTGTTACCAAGGTGAATGAGGAACACCAGAATGCCAAGGATGACCTTTTTGTGAAGAGTCTGGAGGAAACCCTGGCTTTTCTCAATGGTGTCCCTTTCTCAAATTACAAGGAAACCATGTACTTCAAGAGGTTCTTGCAGTGGAAGTGGCTAGAGGCTCAGCCCATCGGTGAGGACTGGTTTTTAGATTTCAGAATCCTGGGCAAAGGAGGGTTTGGTGAGGTCTCTGCCACCCAGATGAGGGGCACGGGGAAACTTTATGCCTGCAAGAAGCTTAACAAGAAGCGCCTCAAGAAGAGGAAAGGCTATGAAGGAGCCATGGTGGAGAAGAGGATCCTGGCCAGAGTGCACAGCCGCTTCATTGTGTCTCTGGCGTACGCCTTCCAGACCAAGACAGATCTGTGTCTGGTAATGACCATCATGAATGGAGGAGACCtaagGTACCATATCTACAATGTCGATGAGAACAACCCTGGCTTTGAGGAGGCCCGAGCCTGCTTCTACACAGCGCAGATCATCTGTGGGATGGAGCACCTCCACCAGAAGAGGATCATCTACAGAGATCTCAAGCCAGAGAATGTGCTTCTGGACAATGATGGTAACGTGCGTATCTCCGATCTTGGCCTTGCAGTGGAGCTGAAGGACGaccaaacaaaaatcaaaggtTATGCTGGAACTCCAGGTTTCATGGCTCCTGAGCTCCTGAAAGGCGAGGAGTACGACTACTCTGTGGACTACTTCACCCTTGGAGTGACGCTGTATGAAATGATTGAAGCCAAGGGTCCATTTCGAACCCGAGGAGAGAAGGTTGAAAACAAGGAGGTTAAGAAGCGCATCCTGAACGATCCAGTGGCTTACTCTGAGAAATTCAGTGAAGAAGCCAAGTCTTTTTGTGAGGCGCTCCTGGCCAAGGAAGTGGACAAGCGATTGGGCTTTAAGAATGGGAACTGCGAAGAGCTCAGGGTGCATCCTTTCTTCAGCAGCATCAACTGGAGGAAACTGGAAGCAGGTATTCTGCCACCACCATTTGTTCCAGACTCAAAAACTGTCTACGCCAAAGACATCCAGGATGTAGGGGCCTTCTCCACAGTGAAGGGTGTCAACCTTGATGAGCCAGACAAAGAATTCTTTGACGAGTTTGCCTCAGGCAACATCTCCATACCTTGGCAGGAGGAAATGTTAGAAACTGGTGTGTTTGGAGAGCTTAACATATGGGGTGCTGGCGGAACGCTACCCAATGATTTGAGGAGAGAGTCAATTTTCGAACCTCCGCCAAAGTCaggtgtgtgtagtgtgtcaTAA

Function


symbol description
grk1a Enables rhodopsin kinase activity. Predicted to be involved in protein phosphorylation and regulation of signal transduction. Predicted to act upstream of or within several processes, including phosphorylation; regulation of rhodopsin mediated signaling pathway; and visual perception. Predicted to be active in cytoplasm. Is expressed in epiphysis; eye; retinal photoreceptor layer; and retinal rod cell. Human ortholog(s) of this gene implicated in Oguchi disease-2 and night blindness. Orthologous to human GRK1 (G protein-coupled receptor kinase 1).
grk1 Enables rhodopsin kinase activity. Involved in protein autophosphorylation and regulation of rhodopsin mediated signaling pathway. Predicted to be located in photoreceptor outer segment. Predicted to be active in cytoplasm. Implicated in Oguchi disease-2 and night blindness.

NR:

description
PREDICTED: rhodopsin kinase

GO:

id name namespace
GO:0038032 termination of G protein-coupled receptor signaling pathway biological_process
GO:0006468 protein phosphorylation biological_process
GO:0005524 ATP binding molecular_function
GO:0050254 rhodopsin kinase activity molecular_function
GO:0004703 G protein-coupled receptor kinase activity molecular_function

KEGG:

id description
K00909 GRK1_7; rhodopsin kinase

RNA


RNA id representative length rna type GC content exon number start site end site
AMCG00014441 True 1692 mRNA 0.50 7 13930882 13939105

Neighbor


gene id symbol gene type direction distance location
AMCG00014440 tfdp1,LOC108266453,LOC108426071,LOC107597491,LOC107748134,LOC107673714 coding upstream 9552 13905849 ~ 13921330 (+)
AMCG00014439 LOC107748345,LOC107577958 coding upstream 27227 13882719 ~ 13903655 (+)
AMCG00014427 NA coding upstream 103331 13820356 ~ 13827551 (+)
AMCG00014425 cul4a,LOC102780633 coding upstream 117003 13791149 ~ 13813879 (+)
AMCG00014426 NA coding upstream 142806 13749673 ~ 13788076 (+)
AMCG00014442 NA coding downstream 5675 13944780 ~ 13965123 (+)
AMCG00014444 tpp2,LOC107665822 coding downstream 146407 14085512 ~ 14105494 (+)
AMCG00014443 NA coding downstream 199301 14138406 ~ 14143073 (+)
AMCG00014445 cpox,LOC107717573,LOC107585846,LOC107657924,LOC107550392 coding downstream 212194 14151299 ~ 14157726 (+)
AMCG00014446 NA coding downstream 221531 14160636 ~ 14160842 (+)
G70054 NA non-coding upstream 234011 13694815 ~ 13696871 (+)
G69961 NA non-coding upstream 550478 13352333 ~ 13380404 (+)
G69959 NA non-coding upstream 595697 13334214 ~ 13335185 (+)
G69833 NA non-coding upstream 948448 12980259 ~ 12982434 (+)
G69778 NA non-coding upstream 1330569 12600104 ~ 12600313 (+)
G70221 NA non-coding downstream 228341 14167446 ~ 14171012 (+)
G70271 NA non-coding downstream 527599 14466704 ~ 14467744 (+)
G70286 NA non-coding downstream 1240740 15179845 ~ 15180820 (+)
G70378 itm2b,LOC108430053 non-coding downstream 1411537 15350642 ~ 15430852 (+)
G70409 NA non-coding downstream 1511673 15450778 ~ 15451268 (+)
AMCG00014423 pou2f1b,LOC107748141 other upstream 241694 13655238 ~ 13689188 (+)
AMCG00014407 LOC107725344 other upstream 679150 13246309 ~ 13251732 (+)
AMCG00014345 NA other upstream 3778969 10147979 ~ 10151913 (+)
G69406 tgfbrap1,LOC102780916 other upstream 3922234 10003058 ~ 10008648 (+)
AMCG00014272 tbc1d23 other upstream 6448322 7464503 ~ 7482560 (+)
AMCG00014456 NA other downstream 250459 14189564 ~ 14205014 (+)
AMCG00014461 NA other downstream 363342 14302447 ~ 14356868 (+)
AMCG00014470 NA other downstream 1282809 15221914 ~ 15242333 (+)
AMCG00014490 rpl31,cnot11,LOC106575914,LOC105022559,LOC106574971,LOC106582250 other downstream 1736526 15675631 ~ 15685899 (+)
AMCG00014508 NA other downstream 2190374 16129479 ~ 16139032 (+)

Expression



Co-expression Network