XLOC_006124 (brf1a)


Basic Information

Item Value
gene id XLOC_006124
gene name brf1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 33368140 ~ 33449639 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012064
aaaaattattgtatattattatatatgttatgCTCTAATGAATGTACTGACAACAAAGTTGCACTCTACGTTTACAAATTACGTCAGCGTGATGAGACAGCGTTTAAACCATGTCATCAGACAGGGAAAACAGCCAAGATTTAACAAGCTACCGAATCCTATATGTCCTTTATTTACAATATGTCGTAACAATTGTTCTGTAAAAGTCAAGTTCGAAAGAACAATAGCGTTTCCGATACCGTGTCATAGTTTCGCACAATATGTTATAATAAACGTGTGCCTTTGTCCCCCCTTTCACGTTCACAATGGTATGAGCCGGTCGCACGCTGACTGGAAACATGTGGCTGTTTTTGATAGTGGAGCGGAATGCCCAGTGTAGCGGCTTGTCATGCAGAGAAACACGTCCGTTTTTTTGGTAAATTAATCAGTGTTACCGTCTGTTAAATAACGGAAATTGGGGAGGTTCACGGTTGTTATCTCGACAAACGAAGCTGGAAGGCCTTTTACGGGCTCTCTGGAGCAGACAGAGCTCATTCCCTGTGTTGTGTGTAAGCTGACTGATCGTGAGCATGGGGCGGTGCAAGACCTGCGGTGGGACAGACATCGATGTGGACCAGGCTCGGGGTGTTGCGGTGTGCATGGGCTGTGGCTCTGTGCTGGAGGACAACATCATCGTCTCTGAGGTCACCTTTGTGGAGAGTGGCGGCGGCGGATCGTCAGCTGTTGGCCAGTTCGTCGCTGGCGATGcatCTGGAAATGTGCCTTCACTGGGAGGAAATTTCCAAACTAGTGTCGGGAGAGAGTCCAGAGCTGCCACTCTGCAGAATGCGAAGCGACAGATAAATCACCTTGGTCATCAGCTTCAGATGAATCAGCACTGTCTGGACACTGCCTTCAACTTTTATAAGATGGCTCTCTCTAAACATCTGACCAAAGGACGCAAATCAACTCATGTCATCGCCGCCTGCCTCTACCTCGTCTGCCGAACCGAGGGAACACCTCATATGCTGCTTGATTTGAGTGACCTCTTGCAGGTGAACGTGTACGTTTTGGGAAAAACATTCCTTGTTTTAGCCAGAGAGCTGTGTATCAACGCACCAGCTATCGATCCATGTCTTTATATCCCACGCTTTGCACAACTGCTGGAATTTGGAGAGAAGAGCCATGAGGTTTCTATGACGGCACTGCGTCTCCTGCAGAGGATGAAGAGAGACTGGATGCACACGGGACGAAGACCTTCAGGCCTCTGCGGAGCAGCTCTCCTGGTTGCGGCCCGTATGCACGAGTTCCGTCGCACAATTAAAGAAGTGATTAGTGTGGTGAAAGTCTGCGAGGCCACGCTAAGGAAAAGGTTGTATGAATTTGAGGACACGCCCACCAGTGAGCTGACTATTGAAGAGTTCATGAAGACTGATCTGGAGCAGGAGTGCGACCCGCCTTCATTCACAGCAGGACTCAGGAAGCAAAAGCTAAAACAGATTGAACAGGAGCTTGCGAAGAAAGTTGATGATATTGAAGGTGAAATATGTGGCTATCAGGATGAGATTGAAGTTGAGTTGGAAAGCTGTAGGCCCAAAGCTAGGGGGATTTATGCATCCTGTTCCAGAGAAGATGATGTGGTTTCCTTGGCATCCTCCAGTCACCTTGATGGAGAAGATGATGAACTGAGGGCAGCCGCATCTCATCTGTGTGGGGAGAATGAAGAGCAGGAGCAAGATGGAGAGAGAGTTTCTCTAACCAAACGGCCCTCGTTATCATTATTGCTTGGAGCGCTGCCCACTTCGGCCAGTTTGGGCCTGTCCGAGTCCATCACCAAAATGGGAGAGGAGAAGGAGAACGATGTGGAGGCAGAAGGCGGTGAGCTAGACCTGAGCGGTATTGACGAAGATGAGATCGATCGGTATATCCTGAATGACAAAGAAGTTAAGGTGAAGACTGAACTGTGGATGATTCAAAACGCAGACTACCTCAAAGAGCAAAAAGaaAAGGAAGAAAGAATAGCAAAAGAAAAGGAGGAAGGTACATATAAAGAGCGGAAGCCTAGAAAGTCAACACGAAGGCGTGAGCCCATCAATGCCAACACTGCAGACGAAGCCATTGAAAAGATGTTAGAACAGAAACGCATCTCCACCAAAATAAACTATGATGTTCTGAAAGACTTGAACAAATCCAGCCCAAAAAGTCCCACTCGCCAGCCTGAAGAAGCTTCAGCTGGAGCCAAAAGAACCCCCGCGGCCCGCCAACGGAAACCCCAACTGACTTCACCCGATATTGGCAAAACTGTCAGCAGCTTTGGCAAGAGgTTACAGCCCCTGGTGCGTGCGCAGCCCTCTAAGAAGCTGGCCCTTGATCAGATAGGCTCTTCTGTTCCAGTGGCGACTCCTGCTGTCTCAGCTCAGACTGCTGTTGTTGTAGAGAGCGGACCAGTGGCTTATGAAGAGCATGCAGATGAGGAAGAAGAGGATGAGGAGGATGAGCACTGTGTCAGTGCCATGCAGTTAATGGGCGGCACTAGTGATTATGGCTATGAattagatgatgatgatggctTCTGAAGTCAGGATGTCTATAGAAAAGACAAACTGATGCTTTTCCTGCTGCTTATGAAAACACAGATGAAACTACTCCTGCTTATACTTGCAAGATGGCTGAGAAATTCACACACTACAGAGGGATGCAGAACTAAACAAGAACAACATGTTTGTGCATTTCCACAGACACGTGCTCTGAGCTCATGTGCACTAACTTATTTAAACTTGCCCAAAGAGAGGAGTACGAGAGTAaatggatgtgtgtgtggtgaTCGAGAGTGATGATATTCTCTCTGGAGTGTGTAAGTCTGCTTGCTAACTGCATTACTCTGTGTTTTAGGCAAATGATGATATATGATCCTGCACATCTAAAGCGATTAGCCCACATGATTCTCAGGCCTTTATGTGGAcaaatgtgtgcatgtgcctTTAACTATTACAGTATACAGGCTTGAAGTAGTATAAAGTGTTATTCTCTAAACCAAGTGTAAGTTTATGTGCTCAGTATTCAGTTTAGAATGGTTAAAATCAGATTAGTTTCTGTATTAAATTAGTGcctttttaatttgtattattatgttgAGCACTGGTCTGGTGGATTATCCTTTTTGTgcttttttgattttatttaatgtttaaaaggtACTTTGaggatgtaatttttttaattggttgTTTTTTCTGGTTTATTATGGAGCTGTGGAAAACAAACCAAAGGAATACTTGAAACACTGTTAAAGTGTCATTAGCTTGATCTTATtgttaatgttaaatattttgaaCAGTTACAAAatggagtatatatatatatatatatatatatttagtttttccaTCGATATAGGAAATGTTTACAATATTCAACTATTTTGAATTGATGTCAGTGAAATGGTACGGCTCTGCAAAAGAATAAGGGAACACTTAAGTAATGATTAGTGGAATTGCTATTAATAGGTATGAGTTTGAGTTGTGTGTCTTTGGGTTTTAAACTACCAATGATGTCCATTTTACTCAAACCGATTGATAGCAGATCCAGAGTAAATGCTTATTGATTAATGATCATATTAAATGGTCTTTATTCATTTTTCCAGAACTATAGATTGATAGTTTATTTCTTTAAggtagaatatatatatttttccatatGCTTCATGTATTTTTAAGGTTAGCGCACAACCAGTATTACTGAAGCAAAACCAACCCATTTAGACTGTGACAAATAACCCAACCTTTAAAAGTAAAAGTGTGTTAGACATGGTCCAAAGGTTATTTGGGATTATTTACCTTGATTTGGACAATCGGAATGAATTTGTTgaatatcaattttttttttgtccgtttcttttctataataataataataacaataataataaataaagtcgATATGCGAGTCCTTGTGATATTAAAACTGGACATGTTCACAATTTTATCATTTGGAGTTGAACGGTTTGGTCTTGCAACAATAGTTGTAACAGTAAAACATAACGCTCTGTTCATTAAACCTAAGCAGTATTAATGGATGAACGAATAAAGAGGAATCATTATGCACCCCGTTTTCTGTTCATCaatcttttcttttcggctcagtccctttattaatctggggtcacatcAGCAGAATGAagctccaacttatccagcatatgttttatgcagcggatgcccttccaggtgcaacccatcactgataaacatccatacacacagactacgaacaatttagctcacccaattcacccatatcacatgtttttggacttatgggggaaatcggagcacccagaggaaacccatgggcccatgaggagaacatgcaaactccacacagaaatgccaactgacccagcaaaggattgaaccagcaaccgtcttgttatgaggccattgtgctacccactgcgccactgtgacgccacgttttctgtttttaaatattttttgtgtgccATTTATAATTCGTCTGCTGTCTGTCTGAATGCTTCGACACCGCGACCTACACCAGGCTGTTTTCTCTGCCAGCTTTCTGGGAAATAAAGCAAGAGTTGAGCATCTGTTTTTAGCTTCATGTGCTCGAGGCTGTTGTGTTTTGGTTGGCATAGAAACATGAGCTGTGGTAATTGTGAGGTCCCGCTGGATGAGACCCTAGAAGTGACCTCGCTCTCATCTCTGCAGGGCAAGGGCTGCTGGGAGTTGAAGTTCTCCGGGTCATCTGTATTTTTATGTGTGCAATGATGATGACGAGGTCTTGCCTTTAAGGCTAGTAAAAGTGGAAAGGAACTCTAGAATAACAACCGATGTTTTGTTACATACTGTACTCTTCCTTCTGTATGCCGAATGTGAAACTACCCAGCTAGAATAAAAAACACATTaggttaggttactttatttatacccgaaggtagatttatttgcagtcaagagtcctccTTTCATAACAGtgccacacacacaaaattaacaTAGTGACAACAACAAATGGACAtaagaacataaaacaaatacaaaacactttcttcaaaaaaaaaaaaaagtatcaataAAC
>TCONS_00012065
GGAATGCCCAGTGTAGCGGCTTGTCATGCAGAGAAACACGTCCGTTTTTTTGGTAAATTAATCAGTGTTACCGTCTGTTAAATAACGGAAATTGGGGAGGTTCACGGTTGTTATCTCGACAAACGAAGCTGGAAGGCCTTTTACGGGCTCTCTGGAGCAGACAGAGCTCATTCCCTGTGTTGTGTGTAAGCTGACTGATCGTGAGCATGGGGCGGTGCAAGACCTGCGGTGGGACAGACATCGATGTGGACCAGGCTCGGGGTGTTGCGGTGTGCATGGGCTGTGGCTCTGTGCTGGAGGACAACATCATCGTCTCTGAGGTCACCTTTGTGGAGAGTGGCGGCGGCGGATCGTCAGCTGTTGGCCAGTTCGTCGCTGGCGATGcatCTGGAAATGTGCCTTCACTGGGAGGAAATTTCCAAACTAGTGTCGGGAGAGAGTCCAGAGCTGCCACTCTGCAGAATG
>TCONS_00012066
GTAAGCTGACTGATCGTGAGCATGGGGCGGTGCAAGACCTGCGGTGGGACAGACATCGATGTGGACCAGGCTCGGGGTGTTGCGGTGTGCATGGGCTGTGGCTCTGTGCTGGAGGACAACATCATCGTCTCTGAGGTCACCTTTGTGGAGAGTGGCGGCGGCGGATCGTCAGCTGTTGGCCAGTTCGTCGCTGGCGATGcatCTGGAAATGTGCCTTCACTGGGAGGAAATTTCCAAACTAGTGTCGGGAGAGAGTCCAGAGCTGCCACTCTGCAGAATGCGAAGCGACAGATAAATCACCTTGGTCATCAGCTTCAGATGAATCAGCACTGTCTGGACACTGCCTTCAACTTTTATAAGATGGCTCTCTCTAAACATCTGACCAAAGGACGCAAATCAACTCATGTCATCGCCGCCTGCCTCTACCTCGTCTGCCGAACCGAGGGAACACCTCATATGCTGCTTGATTTGAGTGACCTCTTGCAGGTGAACGTGTACGTTTTGGGAAAAACATTCCTTGTTTTAGCCAGAGAGCTGTGTATCAACGCACCAGCTATCGATCCATGTCTTTATATCCCACGCTTTGCACAACTGCTGGAATTTGGAGAGAAGAGCCATGAGGTTTCTATGACGGCACTGCGTCTCCTGCAGAGGATGAAGAGAGACTGGATGCACACGGGACGAAGACCTTCAGGCCTCTGCGGAGCAGCTCTCCTGGTTGCGGCCCGTATGCACGAGTTCCGTCGCACAATTAAAGAAGTGATTAGTGTGGTGAAAGTCTGCGAGGCCACGCTAAGGAAAAGGTTGTATGAATTTGAGGACACGCCCACCAGTGAGCTGACTATTGAAGAGTTCATGAAGACTGATCTGGAGCAGGAGTGCGACCCGCCTTCATTCACAGCAGGACTCAGGAAGCAAAAGCTAAAACAGATTGAACAGGAGCTTGCGAAGAAAGTTGATGATATTGAAGGTGAAATATGTGGCTATCAGGATGAGATTGAAGTTGAGTTGGAAAGCTGTAGGCCCAAAGCTAGGGGGATTTATGCATCCTGTTCCAGAGAAGATGATGTGGTTTCCTTGGCATCCTCCAGTCACCTTGATGGAGAAGATGATGAACTGAGGGCAGCCGCATCTCATCTGTGTGGGGAGAATGAAGAGCAGGAGCAAGATGGAGAGAGAGTTTCTCTAACCAAACGGCCCTCGTTATCATTATTGCTTGGAGCGCTGCCCACTTCGGCCAGTTTGGGCCTGTCCGAGTCCATCACCAAAATGGGAGAGGAGAAGGAGAACGATGTGGAGGCAGAAGGCGGTGAGCTAGACCTGAGCGGTATTGACGAAGATGAGATCGATCGGTATATCCTGAATGACAAAGAAGTTAAGGTGAAGACTGAACTGTGGATGATTCAAAACGCAGACTACCTCAAAGAGCAAAAAGaaAAGGAAGAAAGAATAGCAAAAGAAAAGGAGGAAGGTACATATAAAGAGCGGAAGCCTAGAAAGTCAACACGAAGGCGTGAGCCCATCAATGCCAACACTGCAGACGAAGCCATTGAAAAGATGTTAGAACAGAAACGCATCTCCACCAAAATAAACTATGATGTTCTGAAAGACTTGAACAAATCCAGCCCAAAAAGTCCCACTCGCCAGCCTGAAGAAGCTTCAGCTGGAGCCAAAAGAACCCCCGCGGCCCGCCAACGGAAACCCCAACTGACTTCACCCGATATTGGCAAAACTGTCAGCAGCTTTGGCAAGAGgTTACAGCCCCTGGTGCGTGCGCAGCCCTCTAAGAAGCTGGCCCTTGATCAGATAGGCTCTTCTGTTCCAGTGGCGACTCCTGCTGTCTCAGCTCAGACTGCTGTTGTTGTAGAGAGCGGACCAGTGGCTTATGAAGAGCATGCAGATGAGGAAGAAGAGGATGAGGAGGATGAGCACTGTGTCAGTGCCATGCAGTTAATGGGCGGCACTAGTGATTATGGCTATGAattagatgatgatgatggctTCTGA

Function

symbol description
brf1a Predicted to enable RNA polymerase III general transcription initiation factor activity and RNA polymerase III type 3 promoter sequence-specific DNA binding activity. Acts upstream of or within neutrophil differentiation. Predicted to be part of transcription factor TFIIIB complex and transcription preinitiation complex. Predicted to be active in nucleus. Is expressed in several structures, including head; midbrain; notochord; pectoral fin musculature; and polster. Human ortholog(s) of this gene implicated in cerebellofaciodental syndrome. Orthologous to human BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit).

GO:

id name namespace
GO:0030099 myeloid cell differentiation biological_process
GO:0006352 DNA-templated transcription, initiation biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006412 translation biological_process
GO:0006413 translational initiation biological_process
GO:0030223 neutrophil differentiation biological_process
GO:0070897 transcription preinitiation complex assembly biological_process
GO:0070898 RNA polymerase III preinitiation complex assembly biological_process
GO:0000126 transcription factor TFIIIB complex cellular_component
GO:0005634 nucleus cellular_component
GO:0008134 transcription factor binding molecular_function
GO:0017025 TBP-class protein binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding molecular_function
GO:0003743 translation initiation factor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-6334 Predicted to enable RNA polymerase III general transcription initiation factor activity and RNA polymerase III type 3 promoter sequence-specific DNA binding activity. Acts upstream of or within neutrophil differentiation. Predicted to be part of transcription factor TFIIIB complex and transcription preinitiation complex. Predicted to be active in nucleus. Is expressed in several structures, including head; midbrain; notochord; pectoral fin musculature; and polster. Human ortholog(s) of this gene implicated in cerebellofaciodental syndrome. Orthologous to human BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit).

Ensembl:

ensembl_id ENSDARG00000017835

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012064 False 5076 mRNA 0.42 19 33368140 33449639
TCONS_00012065 False 465 mRNA 0.54 3 33368503 33376087
TCONS_00012066 True 2007 mRNA 0.50 18 33373713 33447118

Neighbor

gene id symbol gene type direction distance location
XLOC_006123 dcdc2b coding upstream 53382 33304187 ~ 33314758 (+)
XLOC_006122 iqcc coding upstream 66154 33298338 ~ 33301986 (+)
XLOC_006121 ccdc28b coding upstream 74486 33282095 ~ 33293654 (+)
XLOC_006120 tmem39b coding upstream 86830 33268657 ~ 33281310 (+)
XLOC_006119 oip5 coding upstream 108341 33256847 ~ 33259799 (+)
XLOC_006125 ftr80 coding downstream 2457 33452096 ~ 33458790 (+)
XLOC_006126 ftr81 coding downstream 12593 33462232 ~ 33468697 (+)
XLOC_006127 jag2a coding downstream 38393 33488032 ~ 33551699 (+)
XLOC_006128 cfl1l coding downstream 157100 33606739 ~ 33609427 (+)
XLOC_006129 BX005372.1 coding downstream 201777 33651416 ~ 33689992 (+)
XLOC_006116 NA non-coding upstream 262912 33104911 ~ 33105228 (+)
XLOC_006113 BX470227.1 non-coding upstream 383371 32984654 ~ 32984769 (+)
XLOC_006112 NA non-coding upstream 451214 32906643 ~ 32916926 (+)
XLOC_006111 CR936241.1 non-coding upstream 521531 32846493 ~ 32846609 (+)
XLOC_006105 CR769766.1 non-coding upstream 975641 32392383 ~ 32392499 (+)
XLOC_006133 CR524481.1 non-coding downstream 976609 34426248 ~ 34426365 (+)
XLOC_006135 NA non-coding downstream 1302535 34752174 ~ 34984913 (+)
XLOC_006136 CR376850.1 non-coding downstream 1433607 34883246 ~ 34883370 (+)
XLOC_006137 CR376850.2 non-coding downstream 1519880 34969519 ~ 34969645 (+)
XLOC_006140 CU681845.1 non-coding downstream 2033979 35483618 ~ 35522176 (+)

Expression


Co-expression Network