AMCG00015075 (apex1)


Basic Information

Item Value
gene id AMCG00015075
gene name apex1
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030132.1
NCBI id CM030132.1
chromosome length 32980562
location 1509378 ~ 1517119 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00015075
TTTCACTTATAGACACCCACATGTGATTTTATCGGATGATTTCCTGTTTTAGCTAGTCTGGTGACCCATCTGTCTTCACATGTGGCGTTACTGTGTAATCTGCTTCACTATATTGCActgactttttatttgtatttgttgtacattttatttgtaaaaataatgtagtgaTAGTATATTTTGGATGatattatttcttttaaatcgCACTTAATCTTTTGATTAGAAACCCTACACTCAGGCGATGTGTGGGGCAGCCCTAATAAGCTCACATGGTGTCTACACGAACGGGTGCTTTGTTTGCGAGAGTGAGGGGTTGCAGTTTCAGTGTGTGCGTTTTGTGTATCAGGGACCGTGCAAGGTGTCGCTGTGTGGCCTGTGCAGCTGTGTcagcgtgtctgtctgtggtgtGTGAGCAGGGACAGACGGACAATGTCTAAGAGAGCGAAAAAGAATGTGGAGTGTGACCAGGACAATGTAGCAGTCCCTGAAGTAAAGCGCGGTAAGAAATCTGCAAAGGAGCCAGAGGCCCCAGTCTTGTATGATGACCCGCCGGACCGTCTGACCAGCAAAAACAGCCACCAAGCAAGCCTGCGCATCACCTCCTGGAACGTGGATGGACTGCGGGCCTGGGTTAAGAAGAAGGGCCTGGAGtggGTGCGAGAGGAGGCCCCTGACGTCCTGTGCCTCCAGGAGACTAAGTGTGCCGAGAAATCTCTCCCAGCGGAGATCACGGACATGCCAGAGTTTCCACACAAGTACTGGGCTGGCTCTGAGGAGAAGGAGGGTTACAGCGGGGTGGCCATGCTGTGCAAAACCGAGCCCCTCAACGTCACTTACGGCATCGgcATGGAGGAACATGATAAGGAAGGTCGCGTTATAACTGCAGAGTTCCCTTCCTTCTTTTTGGTGACAGCCTACGTGCCCAACTCTGGCCGTGGCCTTGTGCGGCTGGCATACCGCCAGACCTGGGATGCTGACTTCCGTTCCTACCTGAGTGGCCTGGAGCAGCGCAAGCCCCTGGTGTTGTGTGGCGACCTGAATGTGGCACATGAGGAGATTGACCTACGCAACCCCAAGACAAACCGCAAGAATGCGGGCTTCACAGCGGAGGAGCGCCAGGGTTTTGGGGAGCTGTTGAAGGAGGGCTTCGTGGACAGCTTCCGGTATTTGTATCCTGAGCAAGCACATGCCTACACCTTCTGGACCTACATGATGAACTCCCGTGCCAAGAACGTGGGCTGGCGGCTTGATTACTTCGTGCTGTCAAAGTCCCTGCTGCCCAATCTGTGTGACAGCAAGATCCGCAACACCGCCATGGGCAGTGACCACTGCCCTATCACTCTGCTGCTGGGTTTCTAAATCCCCCTCACAGTGTCCCATTGCCTTTCTGCTAGTGGGAAGGGCAAAGGTTCATGGTCCAAGTCCAGCGGCAGGCTGTTCTGTGATGTCTCGATTTTCTATCTCCTTCAATAAGATTctctgttgttttaaaaagtctCCTGTAGCTTGTAGCTGTTAACCTTCATTTTTATATGACCTGTTTGCGTGTTGTACtctccttttaaataaataaaatttaagaTTGTA

Function

symbol description
apex1 Predicted to enable DNA-(apurinic or apyrimidinic site) endonuclease activity; double-stranded DNA 3'-5' exodeoxyribonuclease activity; and phosphodiesterase I activity. Acts upstream of or within several processes, including heart contraction; heart looping; and negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum; mitochondrion; and nuclear lumen. Predicted to be active in nucleus. Is expressed in head. Human ortholog(s) of this gene implicated in breast cancer; female reproductive organ cancer (multiple); spina bifida; and urinary bladder cancer. Orthologous to human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1).

NR:

description
PREDICTED: DNA-(apurinic or apyrimidinic site) lyase

GO:

id name namespace
GO:0090305 nucleic acid phosphodiester bond hydrolysis biological_process
GO:0006281 DNA repair biological_process
GO:0005622 intracellular anatomical structure cellular_component
GO:0004519 endonuclease activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0016829 lyase activity molecular_function

KEGG:

id description
K01142 E3.1.11.2, xthA; exodeoxyribonuclease III

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00015075 True 1590 mRNA 0.50 5 1509378 1517119

Neighbor

gene id symbol gene type direction distance location
AMCG00015076 NA coding upstream 19419 1487434 ~ 1489959 (+)
AMCG00015067 NA coding upstream 615340 888014 ~ 894038 (+)
AMCG00015058 NA coding upstream 1367575 140790 ~ 141803 (+)
AMCG00015079 NA coding downstream 28112 1545231 ~ 1546105 (+)
AMCG00015080 NA coding downstream 120662 1637781 ~ 1658932 (+)
AMCG00015082 NA coding downstream 161611 1678730 ~ 1682241 (+)
AMCG00015084 tbc1d30,LOC107658925 coding downstream 185401 1702520 ~ 1718774 (+)
AMCG00015085 NA coding downstream 208501 1725620 ~ 1742582 (+)
G95209 NA non-coding upstream 147989 1360813 ~ 1361389 (+)
G95205 etfb non-coding upstream 154643 1347049 ~ 1354735 (+)
G95190 NA non-coding upstream 202381 1306797 ~ 1306997 (+)
G95189 NA non-coding upstream 225332 1283707 ~ 1284046 (+)
G95148 LOC100846954 non-coding upstream 316995 1162969 ~ 1192383 (+)
G95268 NA non-coding downstream 22519 1539638 ~ 1539890 (+)
G95270 NA non-coding downstream 22884 1540003 ~ 1543430 (+)
G95278 NA non-coding downstream 47916 1565035 ~ 1565242 (+)
G95279 NA non-coding downstream 49306 1566425 ~ 1566701 (+)
G95298 NA non-coding downstream 226423 1743542 ~ 1772882 (+)
G95117 NA other upstream 570392 879089 ~ 938986 (+)
G95078 LOC107575789 other upstream 962633 546229 ~ 546745 (+)
AMCG00015077 NA other downstream 1539 1518658 ~ 1539558 (+)
AMCG00015081 LOC107701070 other downstream 65075 1582194 ~ 1596895 (+)
AMCG00015092 NA other downstream 468866 1985985 ~ 2021856 (+)
AMCG00015096 NA other downstream 574556 2091675 ~ 2103854 (+)
G95486 NA other downstream 683818 2200937 ~ 2217102 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000066_01780056_01782937 APEX1 coding CI01000066 null 1779905 ~ 1783092 (-)