AMCG00016669 (hoxb13aa,hoxb13ab,hoxb13)



Basic Information


Item Value
gene id AMCG00016669
gene name hoxb13aa,hoxb13ab,hoxb13
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information


Item Value
chromosome id CM030122.1
NCBI id CM030122.1
chromosome length 54868152
location 27338007 ~ 27339593 (-)
genome version AmiCal1_2021_bowfin_Genome

Sequence


>AMCG00016669
ATGACCACCTCCCTGGTCCTTAATCCGCGCTGGGTGGACTCGGTAATGTTTGTATACGAAAACAACTTGGATGAACTTAACAAGAACATGGAGGGTCTGGTGGGTGCCGGCAATTTCGCAGCCAACCAGTGCAGGAATCTGATGGCCCATTCCGCCCTGGGAGGCCACCCTTCCTCTCTCGTACACGGCTCCGGCTACTCCGCAGTCGATGTGACCGGGGCTGGATCCGTAGAAGCGGGAAAGCAATGCGCTCCGTGCCCGGGGGTTCCCCAGGGGTCTTCCGCTGCTCCTCTGCCATATGGGTATTTCGGCAACGGCTACTACTCCTGCAGAATGGGCAGAGGTGCACTGAAGTCTTGCACCCAACCCAGCGCCCTCTCCAGTTATTCCGCAGAGAAATACATGGACACCCCTGTGGCGTCCGAAGAGTACCCTAGCAGGGCCAAGGAATTCGCCTTCTACCACGGCTATGCCAGTCCCTACCAACCCATGGCCAGCTACCTGGACGTTTCTGTGGTGCAGACAATCAGTGGGGCCGGGGAGCCCCGGCATGAGACGCTGCTGCCAATGGACAGCTATCAGCCGTGGGCACTGACCAACGGATGGGGCAACGTAGTGGCCCACCAGCAAGACGGGAGCTCCTTCCGCCGCGGTAGAAAGAAAAGGATACCTTACACCAAGGCGCAGCTAAAGGAACTGGAAAAAGAATATGCCGCCAACAAATTCATCACCAAAGACAAGAGGAGAAAGATTTCTGCAGTAACCAACCTTTCGGAAAGACAGATTACTATATGGTTTCAAAACCGGAGggttaaagaaaagaaattcGTGGCAAAAGTCAAACCCAGCGCTCCTTAA

Function


symbol description
hoxb13 Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; methyl-CpG binding activity; and sequence-specific double-stranded DNA binding activity. Involved in angiogenesis and negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. Implicated in ductal carcinoma in situ and renal cell carcinoma. Biomarker of cervical cancer; endometrial cancer; and prostate cancer.

NR:

description
homeobox protein HoxB13aa

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0007275 multicellular organism development biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K09298 HOX_13; homeobox protein HoxA/C/D13

RNA


RNA id representative length rna type GC content exon number start site end site
AMCG00016669 True 858 mRNA 0.55 2 27338007 27339593

Neighbor


gene id symbol gene type direction distance location
AMCG00016672 hoxb9ab,hoxb9,hoxb9a,LOC106600835 coding downstream 24834 27299603 ~ 27313173 (-)
AMCG00016673 hoxb8,hoxb8ab,hoxb8aa coding downstream 47146 27286874 ~ 27290861 (-)
AMCG00016674 NA coding downstream 51546 27286213 ~ 27286461 (-)
AMCG00016666 hoxb4,hoxb4ab coding downstream 90010 27247560 ~ 27247997 (-)
AMCG00016665 LOC105013251 coding downstream 118283 27217458 ~ 27219724 (-)
AMCG00016670 LOC106579309 coding upstream 31386 27370979 ~ 27375700 (-)
AMCG00016675 ttll6,LOC107582749,LOC107727303,LOC107666932 coding upstream 36372 27375965 ~ 27381088 (-)
AMCG00016681 snf8,LOC107734219,LOC107692042,LOC107554070,LOC107584075,LOC107660854 coding upstream 90509 27430102 ~ 27433860 (-)
AMCG00016688 nr1d1,LOC102302421 coding upstream 170052 27509645 ~ 27516973 (-)
AMCG00016692 NA coding upstream 304046 27643639 ~ 27650849 (-)
G15016 hoxb9 non-coding downstream 29049 27296085 ~ 27308958 (-)
G15001 hoxb5a,LOC104941372,LOC103365501,LOC108278507,LOC108413114 non-coding downstream 72404 27263713 ~ 27265603 (-)
G14999 NA non-coding downstream 92760 27243966 ~ 27245247 (-)
G14943 nfe2l1,nfe2l1b,LOC107565927 non-coding downstream 354521 26979158 ~ 26983486 (-)
G14882 NA non-coding downstream 595669 26741085 ~ 26742338 (-)
G15066 NA non-coding upstream 55526 27395119 ~ 27398583 (-)
G15071 NA non-coding upstream 73407 27413000 ~ 27413229 (-)
G15073 NA non-coding upstream 76060 27415653 ~ 27415892 (-)
G15074 NA non-coding upstream 76656 27416249 ~ 27416539 (-)
G15075 NA non-coding upstream 84961 27424554 ~ 27424821 (-)
AMCG00016671 hoxb6ab,hoxb6,hoxb6a,LOC105013254,LOC103045875,LOC107582892 other downstream 58673 27265887 ~ 27279334 (-)
AMCG00016662 cbx1,cbx1b,LOC108279860 other downstream 334300 26995173 ~ 27003707 (-)
AMCG00016644 NA other downstream 694514 26626707 ~ 26643493 (-)
AMCG00016643 NA other downstream 745707 26582526 ~ 26592300 (-)
G14843 NA other downstream 766366 26568669 ~ 26571641 (-)
G15026 NA other upstream 29997 27369590 ~ 27370139 (-)
G15067 NA other upstream 62083 27401676 ~ 27403922 (-)
G15076 NA other upstream 85300 27424893 ~ 27428651 (-)
AMCG00016712 NA other upstream 790419 28130012 ~ 28157200 (-)
AMCG00016732 NA other upstream 1441879 28781472 ~ 28785507 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_025300 hoxb13a coding NC_007114.7 CM002887.2 23654233 ~ 23655834 (+)
grasscarp (Ctenopharyngodon idella) CI01000034_01718736_01720031 HOXB13, HOXB13AB, HOXB13A, HOXB13AA coding CI01000034 null 1718606 ~ 1720246 (-)