AMCG00016912 (stat3,LOC107653351)



Basic Information


Item Value
gene id AMCG00016912
gene name stat3,LOC107653351
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information


Item Value
chromosome id CM030122.1
NCBI id CM030122.1
chromosome length 54868152
location 34310868 ~ 34340346 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence


>AMCG00016912
ATGCACAGACAGGTTGTGTCTATGGTAGTGGAGGTCCTGGTCACCATGGCCCAGTGGAATCAATTACAGCAGTTGGACCCCAGGTACCTGGAGCAGCTCTACCACCTGTACAGCGATAGCTTCCCAATGGAGTTGCGGCAGTTCCTCGCCCCCTGGATCGAGAGCCAGGACTGGGCCTACGCTGCCAACAAGGAGTCCCACGCAACACTGGTGTTCCACAACCTACTGGGGGAGATAGACCAACAGTACAGCCGCTTCCTGCAGGAGAACAACGTCCTGTACCAGCACAACCTGAGGAGGATCAAGCAGCACCTGCAGAGTAAGTACTTGGAAAAGCCAATGGAGATTGCCAGGATAGTGGCTCGATGCCTGTGGGAAGAATCTCGATTGCTGCAGactgctactactgctgctcAGAAGATGAAAATGCTGGAGAACCTGCAAGATGACTTTGATTTCAACTACAAGACTCTGAAAAGCCAAGGAGAAATCTCCCAGGATCTGAATGGGAACAGCCAAGCAGCTGCAACTAGACAGAAGATGGCCCAGCTGGAGCAGATGTTAACAGCCCTGGACCAGCTCAGGAGGCAAATTGTGACAGAGATGGCTGGTCTGCTGTCTGCGATGGACTTTGTGCAGAAGAACCTGACAGATGACGAGCTGGCGGACTGGAAGAGGAGGCAGCAGATCGCCTGCATCGGGGGGCCGCCCAACATCTGCCTGGACCGCCTGGAAACATGGATCACCTCTCTGGCCGAGTCTCAGCTGCAGATCAGGCAGCAAATTAAGaagctggaggagctgcagcagaAGGTCTCCTACAAGGGTGACCCCATCGTCCAGCACCGGCCCGCCCTGGAGGAGAAGATCGTGGACATCTTCAGGAACCTCATGAAAAGcgCCTTTGTGGTTGAACGTCAGCCTTGTATGCCCATGCACCCTGACAGGCCTCTGGTCATTAAAACGGGGGTGCAGTTCACAACCAAGGTCAGgttaCTAGTGAAATTCCCTGAATTGAATTACCAGCTGAAAATTAAAGTGTGCATCGACAAGGAATCGGGGGATGTGGCTGCACTCCGAGGGTCTCGTAAATTTAACATACTGGGCACAAACACCAAGGTGATGAATATGGAGGAGTCCAACAATGGCAGCCTCTCTGCAGAGTTTAAACACCTGGCCTCCCTGATAGTGACAGAAGAGCTGCATCTCATCACTTTCGAGACTGAGGTCTACCACCAGGGCCTGAAGATCGACCTGGAGACACATTCCTTGCCTGTTGTGGTCATCTCTAATATCTGTCAGATGCCGAATGCCTGGGCCTCCATTCTGTGGTACAACATGCTGACCAATCACCCCAAGaacGTGAACTTCTTCACCAAACCGCCCGTGGCCACGTGGGACCAGGTGGCCGAGGTCCTGAGCTGGCAGTTCTCCTCCACCACCAAGCGCGGCCTGACCATCGAGCAGCTCACCACGCTTGCTGAGAAACTGCTGGGACCCTGTGTAAACTACTCTGGCTGTCAAATCACATGGGCGAAATTCTGCAAAGAGAATATGGCAGGCAAAGGCTTTTCGTTCTGGGTGTGGCTGGACAACATCATTGACCTGGTGAAGAAATACATCTTGGCCCTGTGGAATGAAGGGTACATTATGGGCTTCATCAGTAAGGAGCGCGAGAGGGCCATTCTCAGCACCAAGCCCCCTGGGACGTTCCTCCTGAGGTTCAGCGAGAGCAGCAAGGAGGGGGGCATCACCTTCACCTGGGTGGAGAAAGACATCAGTGGGAAGACCCAGATTCAGTCGGTGGAGCCCTACACTAAGCAGCAGCTCAATAGCATGTCTTTCGCCGAGATCATCATGGGCTACAAGATCATGGATGCCACCAACATCCTGGTCTCGCCGCTGGTGTACCTGTTCCCAGAGATCCCCAAGGAGGACGCGTTTGGGAAGTACTGCCGTACGGAGAACCCGGAACAGCCAGACTTCACTGACCCAGgcACAGTCCCTTACCTGAAGACAAAGTTCATCTGTGTTACCCCGTGCCCGTCTGTGTTCATGGACATGCCGGACAGTGATCTGCTGGGGAACGGATTCTCCGGCACCAACTCTGGCAACACGAGCGACCTCTTCCCCATGTCCCCACGCACCCTAGACTCCCTGATGCACAACGACGGGGCTGATGCCAACCCTGGAGGGCCACTAGAATCCCTCACTCTGGACATGGAGTTCAGTTCCGACGCAGCGTCCCCCATGTGAACAGGACGGTCACCCAAGATGTCTTTGTATTCGCACAGATAGGAGGCTGATGCTCCATTTTAATccctatctctctttctctccaggCTATTAAGCACCATATTGTAGGTGGAGCACTTTCTTCCATAACCTAGAGGCATGAGCCCAgataaattcatatttaattcttatttttagaCGTTTGTTTTGTCAAGATAAACATCAGCACTTTTGAAGACTCTGTAAATTATGCTGTAACTACTTGCTTCTACTAATGTCTTCTGGATGACTtattaggggggaaaaaactttaattgaattgtaagtTCTACTGTTAAGTGTTTTTTCGCCAGCTCTCTGTAAGTAAGTATAAGAAATTGTGATTATGGTAAAAGTATTACCATATTTTGGAAAGACTGTGAGATGGAAGTTATTTTTCCATAAGTGGAGTCAaaggaacattttttttgtactatTGCTGCAGATGCTGTGGTTGTGATTAAAGTGGTTTACCAGTTACCTCCCAATCACTGCGTCTAATTATGATCCTCACAAAtttggggggggtgggaagGTCTCAGCCTTTTAGTAGGTTTCCAAATGGAAGAGAGGTTAAGAGGTTGGTTTGCTTTTTATGGTTAATTGGATCTCTGGCTTTacaattatgttgtatttttccagtattttcttcactttcctGTGACATTGAAAGGGGAAGTGTGTACAGTTGGTTTTGGTATTTGTATACTCAGATTGTctttagttaaaataaaaaatcccaaaTCAGGAGCTTAGATTAATGCCAGGGATGTTTTTGCACACGTCAGACATCCTGAAAGGTTGTCTGTACTCCatccatttatttctttttctgatATGAACCTGAACAGAAAATGCTTTTCTCTGTAGCCCAAGCTGTGGCTTATGGAAGTGATGTCTGTATTATATTCGCAGGATGTTTGATTCTACCATCCTTGTGGTCACTGCACTGTCAGCTGGTGTCACGGACCTCAATTACCCCTGAGCTTGGACAGCACCACTAAGATATCAGTGGGTAGTCACAGAGCTAATCTGGATCTGTGAAATCAGCCCTATAACGAATAAGTCTGAAAAGAGTATACCAAATTTGAAAATggatttttaaaagcatgtaaTTTTTGTTTGTCTCTTATCTTCATGTGTACGATTTAACTCTGTAGGTGTTACGATTATATCTATGTATCCTAAATTATGACTGTATgcagtaattgttttttgttatgcaATGGATAGAGATGCCTTTGTACTGTGTTTAACCAAAAAGAATAAGAGGAAAAAAGTGTCACAGCACATGTCTGACAGGTGTGTTCCTGGAAGgaagtatttaaacaaaacaaaaaagaagagtATTTTAGTGACCTTGTTTGTGGAGAGATTGGTAGTTTATATTACTATGCCCAGTGGGATTCAAAACCGGTttgacttaattaaaaaaaaaaactaccaaatGATAGGATCCCAAaaggtgtgagtgtgtctgtgccaCTGTTTCAATCTCAACTGGTGTAGCCAGTGTAAGCTGACGGCACTCAGATTGTAAGGCATCCTTGAACGGTGTGGGGAAAAAGATTCAGCCACCAGACTTTTGATCTTTTAGTAGATTTAATAATTCGATGGCCTTTCTAGGAAGTAACCCTCCTCTTGCATGTGCTGTTCTGTCTCTTAACctaaatgtatctattttgttttaaggttCCAAAGGGTATTCAGAGATTGTATCAGCTAGCAAAGTGTCAGGGTGTGTCTCTTTTCTCATTATGTGCAGTAACGTGCTGAAGTGTCAACAAGACAGCTGTATAACTTATAGGCAGTATATAGGCTTGACTGTGCTCTGCCGATGGGTATTTGTTTGTTGGATCAAATGTCCTGTGTTGGTTTTTCAGTCATGTAAATTTCACATGATATCCCCACCCAGTTATTCTGTAAATGATGCTGTAATTACTTGCTTGTACTTTTTAATAAAACCCAAAATagtataatgcaataaaaagcTTTTGTCTTATCTGAAATTTGAGGGTTCACAACATGTAGCAGTCCATTAAGAAATCCAAATAAATCTGTCCTCACTCATGACCTGCTGACTTTggccaaataaattatttttaatgttgcattAATTGTCATTTTAGTCTAAAATTTATCAGGTCACAGAAGCTTTTGTACAGGAGCAAAACTTTAATGTTCATGCACAAACTTGGAGAAAATCTAAttcttctgaaataaattaaaattaaaaaaacatctttggggatagcattttttttgttttgtttaaatgcagtgcCTGTTTCGGTTGCTCCTAAATATGGCTTAGATTTAACCCTCTTTTACAGGTTTAAACTCCTCTTTCTGTCCATTTGCTGAACTCTGGTGGGATGTTGCAATTAAAGTTTCATATTTGAAGAGGGACTTTCCAAATCTTCATGCTTATGTACAATGTTCTTGTTACTTTCCCCTTATTTCTGCAAACTTTCCACTACCACGTGTGATGCTGGGAATGCATACTCACACCATGAATCTTGTTAGCAATCCTGGTCAGCTCGGGAAAAACTTGATAGTgaaaaggatatatatatatataagtgatGCTTCtgattgatttgtattaaaa

Function


symbol description
stat3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including animal organ development; cardiac muscle tissue regeneration; and generation of neurons. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including blastomere; epidermal superficial stratum; head; immature eye; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); hyper IgE recurrent infection syndrome 1; reproductive organ cancer (multiple); and type 2 diabetes mellitus. Orthologous to human STAT3 (signal transducer and activator of transcription 3).

NR:

description
PREDICTED: signal transducer and activator of transcription 3 isoform X1

GO:

id name namespace
GO:0042074 cell migration involved in gastrulation biological_process
GO:0001736 establishment of planar polarity biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0007259 receptor signaling pathway via JAK-STAT biological_process
GO:0001837 epithelial to mesenchymal transition biological_process
GO:0061026 cardiac muscle tissue regeneration biological_process
GO:0060252 positive regulation of glial cell proliferation biological_process
GO:0030010 establishment of cell polarity biological_process
GO:0008045 motor neuron axon guidance biological_process
GO:0060042 retina morphogenesis in camera-type eye biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005509 calcium ion binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0004871 obsolete signal transducer activity molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K04692 STAT3; signal transducer and activator of transcription 3

RNA


RNA id representative length rna type GC content exon number start site end site
AMCG00016912 True 4885 mRNA 0.45 23 34310868 34340346

Neighbor


gene id symbol gene type direction distance location
AMCG00016914 ptrfb,LOC105935706,LOC102209316,LOC102787483,LOC101465061,LOC103482185,LOC103142478 coding upstream 14035 34294213 ~ 34296833 (+)
AMCG00016913 ptrf,LOC103029568,LOC105905374,LOC105028466,LOC107742253,LOC107664665,LOC103381660 coding upstream 39450 34268998 ~ 34271418 (+)
AMCG00016910 NA coding upstream 119119 34169488 ~ 34191749 (+)
AMCG00016905 spop coding upstream 509058 33791287 ~ 33801810 (+)
AMCG00016906 spop,LOC107754841 coding upstream 537335 33761418 ~ 33773533 (+)
AMCG00016916 NA coding downstream 19881 34360227 ~ 34435938 (+)
AMCG00016915 LOC105013349,LOC103368144,LOC102309899 coding downstream 104055 34444401 ~ 34472634 (+)
AMCG00016917 NA coding downstream 140787 34481133 ~ 34499652 (+)
AMCG00016918 LOC106601024,LOC106607294,LOC103359488 coding downstream 218193 34558539 ~ 34597579 (+)
AMCG00016919 NA coding downstream 271297 34611643 ~ 34614856 (+)
G16552 NA non-coding upstream 205181 34104456 ~ 34105687 (+)
G16542 NA non-coding upstream 315486 33993182 ~ 33995382 (+)
G16512 NA non-coding upstream 659579 33651081 ~ 33651289 (+)
G16395 NA non-coding upstream 982526 33325094 ~ 33328342 (+)
G16351 NA non-coding upstream 1130429 33180239 ~ 33180439 (+)
G16646 NA non-coding downstream 257476 34597822 ~ 34599917 (+)
G16668 NA non-coding downstream 395991 34736337 ~ 34736549 (+)
G16692 NA non-coding downstream 435479 34775825 ~ 34777047 (+)
G16698 NA non-coding downstream 480851 34821197 ~ 34821413 (+)
G16705 nkiras2,kbrs2,LOC106607286 non-coding downstream 751113 35091459 ~ 35094092 (+)
G16550 NA other upstream 210005 34100315 ~ 34100863 (+)
AMCG00016909 mien1,LOC107566883,LOC107755209 other upstream 211272 34093276 ~ 34099596 (+)
G16546 NA other upstream 263148 34047371 ~ 34047720 (+)
AMCG00016901 NA other upstream 636507 33668593 ~ 33674361 (+)
AMCG00016898 NA other upstream 660788 33630012 ~ 33650080 (+)
AMCG00016934 acly,aclya,LOC103369716,LOC108273769 other downstream 818251 35158597 ~ 35204232 (+)
G17193 NA other downstream 4155705 38496051 ~ 38503632 (+)
AMCG00016979 NA other downstream 4898727 39239073 ~ 39254490 (+)
G17697 NA other downstream 8050951 42391297 ~ 42397787 (+)
AMCG00017078 LOC106565757 other downstream 9785868 44126214 ~ 44137931 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000034_05681798_05699059 RBTSTAT3, STAT3 coding CI01000034 null 5681493 ~ 5699120 (-)