XLOC_006184 (hps1)


Basic Information

Item Value
gene id XLOC_006184
gene name hps1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 40686133 ~ 40716702 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012171
GCGTCTCGGAAGCTCATCGGCGCCATCTTGTGCAAGTAGCCTAGGGGGAGATCGCACACGGCATCAGATGAGGCGTAAACTTTAGTTTCATCCTGGAGGAACCAAAAGCTGTCGGCTTCTGAGGAACACCCTGTCAGGTAAAATGAAGTGTCTGCTGGTGGCCAATGAGAGCGCAGAGGTTCTGTTCTACTGGACGGACAGCGAGTTCGAACAGCGGCTTCAGGAGCAGTATGGAGTCTCCCAGGAGGAAGGAGAaggactgcctgcctttgaaGACAGCATTAACACTCTCTTCGCACCAATCATCATC
>TCONS_00012172
ttACGGAAGCGCTGTAGCAGTTCAGCAGCTGATGACAAACTAATCGTTGTTCGGTGAGCTGGACCAGGATTCAGAAACAATGACACTTTTCTGCTGTAAACGCCAACAGCTAAAACAGCATCAGATGAGGCGTAAACTTTAGTTTCATCCTGGAGGAACCAAAAGCTGTCGGCTTCTGAGGAACACCCTGTCAGGTAAAATGAAGTGTCTGCTGGTGGCCAATGAGAGCGCAGAGGTTCTGTTCTACTGGACGGACAGCGAGTTCGAACAGCGGCTTCAGGAGCAGTATGGAGTCTCCCAGGAGGAAGGAGAaggactgcctgcctttgaaGACAGCATTAACACTCTCTTCGCACCAATCATCATCTCCTGTAGCACCATGGTGGACCGACTCGGGGACAATTACACCTCCTTCAGCACAGAGAACAATCATATCTATGTTCTGCATCAGTTTGATGAGTGCCTGTACATCGCTGTGAACGGAGACGGAGAGGAGACCGAAGAGGATTTGAAGAGAAAGATCTACGTGATGAAGAAACTCACAGAAATCCTGTTTGGGATGGTGACGCTCAGCGGCCCCCTCCTGAGGAAAGAACTGCGCCCTCAAGACACAGAGCAGAGGAACCGGTTGTGGAAAAAACTGCGAAGCCTCTTGGAGACATACAGCCGCTTGCGTGAAAATGACCAAAGCTTTTTAGTGGAGGCAGTGGAGAGGCTGATCCACCCGACCCTTTGTGAGCAGTGCATTGAGTTTCTGGAGCGTCGACTGGTACAGCAGATTAACAGCAGCATGGACCGAGCCGGTGAGGAGGTGCTGCACGCATTCATACTGGTGCACACCAAACAGCTGGCCTTCTACTCCAGTCGTAATGCCAGCAATCTGAACCCTTCTGATCTCCTGGCTCTGATCATACTGGTGCAAGATCTTTATCCCAGCAAAATAGACCTGGATGACACTCCTGAGGAGCTGGAGAACAGTACAGTTCCTGATGTTTTTTACACACCAGAGCCATCTCCTCCTGAACGAGAATCAGTCACACCAAGAAAGGACAGTCCTCCTGTCTTCCAGTTTGTGGATCCTGATATTCAGATGGCTGAGGACAGTCTACAAACTCTTGAAGTTTCAACCCCTGACCCTTCATCGCCGTCAAGAGTGTTTCTGGAAGCCAAAGAGTGTCCCATGATGCCTCACTCCATGTATTGCCTGTCTCTATGGCCTGGTATCACACTAGTGCTGCTCACCAAGATCCCCAACAGTCATATGGCGGTGTCGGTTTACTACTTTCTGGAGGCTTTCGTCAAGCTGGAGAAGAGGTTAGGTGAGGGCCATGAAGGGGCTTCAGCCATGCGGGGTCAGTCCTCTGTCCAGGAGCAGCGGAGCAAACTGGAGAAGTTCATTAAAGCCTGGTCCAGCATGGAGATTCAGACTTTGCAACTCCAAAATGCTTGGACAGACTTTAAGAACAAGGCCTTCAGCAGATCTGGGACTGGATTTACTAGAGAtTTGCTGCCGTCTTGTAGAAACATGAAGACTCAGCTGTGTGGTGTGTACAGGCAGTTTTTCGCAGCTGAATGTATGGGCAGCAGTCAGCGGTTGGCTCCTCATCTGCAAGAACGGGCTCTGAACATGGTCCAAGAGAAGCTGATGGACTGGAAGGATTTTCTTCTTGTTAAAAGCAAAAGAAACATCACAATGGTGTCATACCTGGAGGAGTTTCCTGGTCTCATCCACTTCATCTACGTGGATCGCTCAAGTGGTCAAATGATCGCACCCTCTCTGAATGTGACTGATCGCACCGTCTCTGAGCTCGGAAAGGGTCCTCTAGCTGACTTCATAAAGAAAAAGGTTTGGAGTCTTGTAGCAACAGCACGACGGTATCTGCACAAGGGTTATGCTACCGTCACACTTCGAGATGGGGATTACTTCTACTGTTACTTCCTGTGGTTTGAGAATGAAACGGGCTACAAACTGGAAGTGACAGACATACCCAGTTGTCCAGATGACACCGCTCCAATAGGAATGCTCACATTTGATTATTATAGGAAACTGCTGCGGTACTACAGCAAAAAACATCAGAATGAAGTGGTGAAGTGTTATGAACTGCTGACTGTTCACCTGGGCGTGATCCCTAATGAATATATTCTCCAGCACTGCAGCCAACTGGCCCGCAAGCTATGGGAGCCAACCCGCATCCCACTCCTGTGACAATCCACATACACACTCCTCATATCAATTTATTCTGTAGCTGCATGATCTGTAATCTAGATGAAGACTTTTCTGCACTTTCTGCACAAGCACTTCCTTGTTTCAGTTCAGGTAACTCACTGTAGAAAACACTGGCGGGGAAACGAAACATCGCGTTTCTTGCTCTTCATTAACAAACTAAATGTAATGTGCAAATGAACAGAGGAACAACTACTTTATGGTGCTCATAATGCAAAAACATGTCTGTTATTTTTAACTGATGCTTTTTGTGATACCTGGACCAAATATTATAGTAAAGACCCTTTAAAATGCCATGAGAAGTCGCATAAGCTGAACTGCTAGTTCTTTAAGCAAATCATTTACATTATTAAACCAGTCATCAATGACTACAAATGtagtaaataaatgactaaaaggtGTAAAGGTTTActccaaaatgaacattttgatGCTAATTTTCTCTGCCTCAGGCCATCCTAGATATGGCagctttttttcttcagtggaCCACAGCATTTCACAAGACTAAATTAGAAATTTTAAATGACCAAAAAACATTGATAGGCCGACAGCAGGgttgtccaaagtcggtcctggagggccggtgtcctgctgagtttagctccaacttgcttcaacacacctgcacggaagtttctagtatatctagtaagcttgattagctggttcaggtgtgttttattagggttggagctaaactctccaggacaccggccctcctggaccgagtttggacaccactggccTACAGGCAAAGCATTGTCTCCGGTGATTTATTTGAGGTGATATGAAGTGAAGTGACCAATGCAGTAACATTGTTTGAATAttattgacaacaaaaaaaagaactttatttacaacattattatttttttaatccaccGTCTAGTAAAATGGTCTTGAGCGATTCCCGGTTTGCGAATGgatatttgaatgattctttttTGAGAACTAGTGAATCAGTTCACCAAATCAACTGAACTGTCTGAAACAGTTTGCGTGAGGTAGCACTTTTAAAATTTCAGACAGTCATTCTTACTTGAAGTGAACCAATCTACTGTTTATCAATCATAAATCATAATTCCGAACGATATTAGGAATGTATGATGCCATGTTTGCAAACTTGTTCAATGCTTCAGTTACTTGCATTGACTAAACTAAGCAAACGGTTCTGAAGAAATTGCGAGCTGCAATGAAAGTTTTTATgatctttaaattttttatgtcaGTGAAGTTGTTAAAGACTGTATTTACTTTAAATGCTTTCGACATGTAAAGCTTCCCCATTTCATGTGATATTGGTTGATTTGATCTTGAGCTCATGCCTTGTGAGTCATCATCATTCAGTCATTTGAATCCGAAAAGattccataagaaaaaaatacaatgtagcAATTTATAGTAAACAGTGTTTAAAGTGTGAactattcattcgttcattttccttcggcttaatccttttattaatttggggtccccAAGCATAGGTTTTACGCAGAAAGTGCcgttccagctgctacccatcactgggaaacacccatacgctctcattcacacacattcactatggacaatttagcttactcaattcacgtgtaccgcatgtctttggacttgtcagggaaagcggagcacccggaggaaacccatgcgaatgcggggagaacatgcaaactggttAAGCACTGGTTTAAATGAGCTCAATATAATTAAAGTCTCACATTTTATTTGATTCGACTTAAAATTTAAATCAACTATCAatttagttttactacagtaagctGTGAAGAATTATAGAAGATGAAACTGTACATGCAGAAATTTTACCTCAAAATACCACAACAGATTAGTACTTTAGTATGCATGCTTTTTTTCCATATCGGGAAAAAGGGTTTTAGTTGAAGatctactgaaaagaaaaaagtcCTATACAACTTGAATAGACCAAGGATGTGTAGAGtaacagaaaatgtttattttgggatGTGCTATCCCCTGTAAGTTATAACTGAAAAATACAAATCTACATCTTAAAAGAAAAGTGTCAGTTTATTTGTCCAGCAGCCAAAAACATCCAATGTATCGCATAGCAGAATTCATTTcttgaaacacttttttttttttttttgtagctgtaATTCTTGATCATGAATGTTGTTACACACATACAACAAAACATTCCCCGAGTTAAAATTGTAGTTAAAGAAATCTAGCGAAAGTGTTTTTTACTCTCTGATTTAGgtgttaaaatataaaagtgaTGTTTTTTTACATGACTGAATGTTTTTCTCTGTACGCTGAAATCTCATTTATACTTTGCTTGAATAAATACAgaatctaaaacattttttacacaatatgtaaaatatgtattgGTGTTTGACgagataaataaatatgaaataattttcaGAA
>TCONS_00012173
AGATGGCTGAGGACAGTCTACAAACTCTTGAAGTTTCAACCCCTGACCCTTCATCGCCGTCAAGAGTGTTTCTGGAAGCCAAAGAGTGTCCCATGATGCCTCACTCCATGTATTGCCTGTCTCTATGGCCTGGTATCACACTAGTGCTGCTCACCAAGATCCCCAACAGTCATATGGCGGTGTCGGTTTACTACTTTCTGGAGGCTTTCGTCAAGCTGGAGAAGAGGTTAGGTGAGGGCCATGAAGGGGCTTCAGCCATGCGGGGTCAGTCCTCTGTCCAGGAGCAGCGGAGCAAACTGGAGAAGTTCATTAAAGCCTGGTCCAGCATGGAGATTCAGACTTTGCAACTCCAAAATGCTTGGACAGACTTTAAGAACAAGGCCTTCAGCAGATCTGGGACTGGATTTACTAGAGAtTTGCTGCCGTCTTGTAGAAACATGAAGACTCAGCTGTGTGGTGTGTACAGGCAGTTTTTCGCAGCTGAATGTATGGGCAGCAGTCAGCGGTTGGCTCCTCATCTGCAAGAACGGGCTCTGAACATGGTCCAGTATGTCTGAAAAGATAACGCTTTAAGTTGATGAATATTATGTGCTTTAGAaacaaagggttagttcacctaaaaatgtccaATCCCCTGAGACTTTTGTACatattcagaacacaaattaagctattttagatgaaatccaggagctctctaACCCTTGGTAGACAGCAAAGGTCACAAGTCATTCAGAAAATGAACCAAATATATTGTCGAGGTATTCCATGTTACTTGAGTGGTTCAagtgtaatcatatgaagctccatgAACACTTTTatgcacc

Function

symbol description
hps1 Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in melanosome assembly. Predicted to act upstream of or within vesicle-mediated transport. Predicted to be part of BLOC-3 complex. Is expressed in optic vesicle; pancreas; pancreatic bud; retina; and retinal pigmented epithelium. Used to study proteinuria. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome 1 and oculocutaneous albinism. Orthologous to human HPS1 (HPS1 biogenesis of lysosomal organelles complex 3 subunit 1).

GO:

id name namespace
GO:0008150 biological_process biological_process
GO:1903232 melanosome assembly biological_process
GO:0031085 BLOC-3 complex cellular_component
GO:0005085 guanyl-nucleotide exchange factor activity molecular_function

KEGG:

id description
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-051113-152 Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in melanosome assembly. Predicted to act upstream of or within vesicle-mediated transport. Predicted to be part of BLOC-3 complex. Is expressed in optic vesicle; pancreas; pancreatic bud; retina; and retinal pigmented epithelium. Used to study proteinuria. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome 1 and oculocutaneous albinism. Orthologous to human HPS1 (HPS1 biogenesis of lysosomal organelles complex 3 subunit 1).

Ensembl:

ensembl_id ENSDARG00000026170

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012171 False 310 mRNA 0.53 4 40686133 40696372
TCONS_00012172 False 4642 mRNA 0.42 19 40692804 40716702
TCONS_00012173 True 827 lncRNA 0.46 4 40707088 40710256

Neighbor

gene id symbol gene type direction distance location
XLOC_006183 hpse2 coding upstream 18056 40501455 ~ 40668077 (+)
XLOC_006182 got1 coding upstream 229138 40437550 ~ 40456995 (+)
XLOC_006181 NA coding upstream 266829 40360160 ~ 40419304 (+)
XLOC_006180 slc25a28 coding upstream 331820 40334727 ~ 40354313 (+)
XLOC_006179 NA coding upstream 355759 40327560 ~ 40330374 (+)
XLOC_006185 ankrd2 coding downstream 12916 40729618 ~ 40741005 (+)
XLOC_006186 BX294129.1 coding downstream 37878 40754580 ~ 40808436 (+)
XLOC_006187 nkx1.2la coding downstream 53926 40770628 ~ 40775530 (+)
XLOC_006188 prkg1a coding downstream 98310 40815012 ~ 40955599 (+)
XLOC_006189 NA coding downstream 271713 40988415 ~ 40989361 (+)
XLOC_006177 BX005216.1 non-coding upstream 716668 39969349 ~ 39969465 (+)
XLOC_006176 NA non-coding upstream 812505 39845264 ~ 39873628 (+)
XLOC_006175 NA non-coding upstream 958669 39684471 ~ 39727464 (+)
XLOC_006191 NA non-coding downstream 1080265 41796967 ~ 41799750 (+)
XLOC_006193 NA non-coding downstream 1104929 41821631 ~ 41854384 (+)
XLOC_006194 NA non-coding downstream 1142302 41859004 ~ 41863031 (+)

Expression


Co-expression Network