AMCG00018867 (ptpn11)


Basic Information

Item Value
gene id AMCG00018867
gene name ptpn11
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030135.1
NCBI id CM030135.1
chromosome length 28454832
location 22987225 ~ 22993237 (-)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00018867
TGGTTTCACCCAAATATCACCGGTGTGGAGGCGGAAAACCTGCTGCTGACTCGAGGTGTGGATGGGAGTTTTTTGGCCCGGCCTAGCAAGAGTAACCCCGGGGATTTCACTCTGTCAGTGAGACGAAATGGAGCCGTCACCCACATCAAGATCCAGAACACGGGGGACTACTATGACCTGTACGGGGGGGAGAAGTTTGCCACGCTGGCTGAATTAGTACAATATTACATGGAGCACCACGGGCAGCTGAAAGAGAAGAACGGAGATGTCATCGAGCTGAAGTACCCACTGAACTGTGCCGATCCCACGTCTGAGAGATGGTTCCACGGGCACCTGTCAGGCAGAGAGGCTGAGAAGCTGCTCACGGAGAAAGGGAAGAACGGCAGTTTCCTGGTGCGAGAGAGCCAGAGCCACCCCGGGGACTTTGTGCTGTCTGTAAGGACGGGAGATGACAAGGGGGAGAGCAGCGATGGCAAGCCTAAGGTCACGCATGTCATGATCCGCTGCCAGCATGACCTCAAGTACGATGTGGGCGGAGGTGAGAAGTTTGACTCCCTGACTGACTTGGTGGAACATTATAAGAAGAATCCGATGGTGGAAACGTTGGGCACTGTGCTCCAGCTCAAACAGCCTCTGAACACAACGCGGATCAACGCAGCCGAGATCGAGAGCCGAGTTCGGGAGCTGAGCAAGTTGGCTGAAGCTACGGACAAGGTTAAGCAGGGCTTCTGGGAGGAGTTTGAGACTCTGCAGCAGCAGGAGTGCAAGCTGCTGTACAGCCGCAAAGAAGGACAGAGAGCCgagaataaaaacaagaacCGATACAAGAACATCCTGCCCTTTGATCATACGAGGGTAGTGCTAAATGACGGGGACATGAATGAGCCGGGCTCAGATTATATCAACGCTAACATCATAATGCCTGAGTTTGAGACAAAGTGTAACAACACCAAGTCCAAGAAGAACTATATTGCCACACAAGGTTGCCTGCAAAACACTATTAGTGACTTCTGGAGAATGGTGTTCCAGGAGAACTCTCGTGTGATTGTCATGACCACCAAGGAAGTGGAGAGAGGAAAGAGTAAATGTGTGAAGTACTGGCCGGACGTGTCCGCGCTGAAGGAGTACGGAGCGATGCGCGTCCGCAACGTCAAAGAGACCTCGGCGCACGACTACAACCTCAGAGAGCTGAAGCTATCGAAGGTTGGGCAGGGCAACACCGAGCGGACCGTGTGGCAGTACCACTTCCGAGCCTGGCCAGACCATGGTGTTCCTGGTGACCCGGGTGGTGTGCTAGACTTCCTGGAGGAGGTCAATCTCAAACAGGAGAGCATCCTGGAGGCCGGGCCCATCGTGGTGCACTGCAGTGCTGGGATTGGACGAACAGGAACATTTATTGTAATAGACATTCTGATTGATATAATCAGAGAAAAAGGGGTAGACTGTGACATCGACGTTCCCAAAACCATCCAGTTGGTGCGATCGCAGCGGTCAGGAATGGTGCAGACGGAGGCCCAGTACAGGTTTATTTACATGGCTGTGCAGCACTATATTGAGACTCTGCAACGCAGGATCGAAGAGGAGCAGAAGAGCAAAATTAAAGGGCGGGAGTACACCAACATAAAGTATTCGCTCTCAGACCTGACAGGGGGAGACCAGAGCCCGTTACCGCCCTGCACCCCCACGCCAACCTGTGCCGAG

Function

symbol description
ptpn11 Enables several functions, including insulin receptor binding activity; non-membrane spanning protein tyrosine phosphatase activity; and phosphotyrosine residue binding activity. Involved in several processes, including animal organ development; positive regulation of signal transduction; and transmembrane receptor protein tyrosine kinase signaling pathway. Located in cytoplasm and nucleus. Part of protein-containing complex. Implicated in several diseases, including Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 1; atrophic gastritis; juvenile myelomonocytic leukemia; and metachondromatosis. Biomarker of anogenital venereal wart; cervical cancer; and glaucoma.

NR:

description
PREDICTED: tyrosine-protein phosphatase non-receptor type 11

GO:

id name namespace
GO:0035335 peptidyl-tyrosine dephosphorylation biological_process
GO:0005737 cytoplasm cellular_component
GO:0004725 protein tyrosine phosphatase activity molecular_function

KEGG:

id description
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00018867 True 1701 mRNA 0.53 13 22987225 22993237

Neighbor

gene id symbol gene type direction distance location
AMCG00018862 NA coding downstream 59790 22899552 ~ 22927435 (-)
AMCG00018863 NA coding downstream 100181 22876661 ~ 22887044 (-)
AMCG00018858 bup1,upb1 coding downstream 111465 22871159 ~ 22875760 (-)
AMCG00018855 snrpd3,LOC105014836 coding downstream 124446 22861091 ~ 22862779 (-)
AMCG00018857 NA coding downstream 136503 22839532 ~ 22850722 (-)
AMCG00018868 aldh2,LOC106578507,LOC107662045 coding upstream 5398 22998635 ~ 23011253 (-)
AMCG00018866 NA coding upstream 19185 23012422 ~ 23032810 (-)
AMCG00018864 NA coding upstream 41132 23034369 ~ 23047483 (-)
AMCG00018865 NA coding upstream 63083 23056320 ~ 23083052 (-)
AMCG00018869 NA coding upstream 93524 23086761 ~ 23087315 (-)
G119181 NA non-coding downstream 2453 22984184 ~ 22984772 (-)
G119180 NA non-coding downstream 3659 22982866 ~ 22983566 (-)
G119129 NA non-coding downstream 129546 22834759 ~ 22857679 (-)
G119128 NA non-coding downstream 221199 22762360 ~ 22766026 (-)
G119072 NA non-coding downstream 320015 22666929 ~ 22667210 (-)
G119235 NA non-coding upstream 116364 23109601 ~ 23111520 (-)
G119382 NA non-coding upstream 1526176 24519413 ~ 24608462 (-)
G119384 NA non-coding upstream 1572909 24566146 ~ 24568299 (-)
G119426 NA non-coding upstream 1843550 24836787 ~ 24842121 (-)
G119466 NA non-coding upstream 2051714 25044951 ~ 25045344 (-)
G119144 NA other downstream 180887 22804345 ~ 22806338 (-)
G118936 NA other downstream 873530 22080464 ~ 22113695 (-)
G118727 NA other downstream 2289398 20696834 ~ 20697827 (-)
AMCG00018805 eif2b1,LOC106580370,LOC106585290 other downstream 2297303 20683666 ~ 20689922 (-)
AMCG00018797 NA other downstream 2308788 20644885 ~ 20678437 (-)
AMCG00018898 NA other upstream 2082161 25075398 ~ 25084586 (-)
G119538 LOC108444117,LOC105014832,LOC106563153 other upstream 2141534 25134771 ~ 25171644 (-)
G119545 NA other upstream 2192970 25186207 ~ 25187408 (-)
AMCG00018929 NA other upstream 3458487 26451724 ~ 26485315 (-)
AMCG00018930 NA other upstream 3784398 26777635 ~ 26797720 (-)

Expression


Co-expression Network