AMCG00019173 (cdk5,LOC106599847)



Basic Information


Item Value
gene id AMCG00019173
gene name cdk5,LOC106599847
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information


Item Value
chromosome id CM030124.1
NCBI id CM030124.1
chromosome length 51038645
location 6908133 ~ 6917381 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence


>AMCG00019173
ATGCAGAAATATGAGAAGCTGGAGAAGATCGGGGAAGGTACTTATGGAACAGTCTTCAAAGCCAAAAACAGAGAGACCCATGAGATTGTAGCTCTTAAAAGAGTGCGCTTAGATGACGACGACGAGGGTGTACCGAGTTCAGCATTGCGGGAAATCTGTCTTTTGAAAgaactaaaacataaaaatatagtCAGGTTGCACGATGTCCTGCACAGTGATAAGAAGTTAACCTTAGTGTTCGAGTACTGCGACCAGGACCTGAAGAAGTATTTTGATAGCTGCAATGGTGACTTAGACCCCGAGACCGTTAAGTCCTTCATGTACCAGCTCTTGAAAGGGTTGGCGTTCTGTCACAGCCGCAACGTGCTGCATCGCGACCTCAAGCCACAGAACCTGCTCATCAACAGGAACGGAGAGCTGAAACTGGCTGATTTTGGCTTGGCTCGGGCGTTTGGGATTCCAGTCAGGTGTTACTCAGCCGAGGTGGTGACGTTGTGGTACCGCCCCCCCGATGTGCTGTTCGGGGCGAAGCTGTACTCTACCTCCATTGACATGTGGTCGGCAGGATGCATATTTGCAGagTTGGCCAACGCTGGACGGCCGTTGTTTCCTGGGAACGATGTGGACGACCAGCTCAAGAGGATTTTCCGATATCCTTTGCACAGGACGCCGACAGAGGAGCAATGGCCGACAATGACCAAACTTCCCGATTACAAGCCCTACCCAATGTATCCTGCTACCACCTCACTGGTGAATGTCGTTCCAAAGCTCAGTGCCACAGGCCGGGACCTCTTACAGAATCTGCTGAAGTGCAATCCGGTGCAGCGGATCTCCGCCGAGGAGGCCCTGCAGCACCCGTACTTCGCCGATTTCTGTCCCCCATGCCGCCCCCCGACGGCGGCCAGCACCCGGAGTCAGACCCGCTTCACCCCAGAGTTTCACACCCCAGACACGTCGAGCCCCAGGACACCCCCGCCCTGA

Function


symbol description
cdk5 Enables cyclin-dependent protein serine/threonine kinase activity and histone kinase activity. Acts upstream of or within several processes, including nervous system development; retina morphogenesis in camera-type eye; and type B pancreatic cell differentiation. Predicted to be active in cytoplasm and nucleus. Is expressed in blastomere; central nervous system; immature eye; musculature system; and neural plate. Human ortholog(s) of this gene implicated in Alzheimer's disease and lissencephaly 7 with cerebellar hypoplasia. Orthologous to human CDK5 (cyclin dependent kinase 5).

NR:

description
PREDICTED: cyclin-dependent-like kinase 5

GO:

id name namespace
GO:0021634 optic nerve formation biological_process
GO:0007049 cell cycle biological_process
GO:0016572 histone phosphorylation biological_process
GO:0051301 cell division biological_process
GO:0021954 central nervous system neuron development biological_process
GO:0048935 peripheral nervous system neuron development biological_process
GO:0010842 retina layer formation biological_process
GO:0043524 negative regulation of neuron apoptotic process biological_process
GO:0060059 embryonic retina morphogenesis in camera-type eye biological_process
GO:0050321 tau-protein kinase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004693 cyclin-dependent protein serine/threonine kinase activity molecular_function
GO:0035173 histone kinase activity molecular_function

KEGG:

id description
K02090 CDK5; cyclin-dependent kinase 5

RNA


RNA id representative length rna type GC content exon number start site end site
AMCG00019173 True 981 mRNA 0.54 13 6908133 6917381

Neighbor


gene id symbol gene type direction distance location
AMCG00019172 NA coding upstream 150 6897818 ~ 6907983 (+)
AMCG00019171 NA coding upstream 75548 6823235 ~ 6832585 (+)
AMCG00019168 NA coding upstream 137916 6769243 ~ 6770217 (+)
AMCG00019167 LOC106569335 coding upstream 202241 6704357 ~ 6705892 (+)
AMCG00019169 NA coding upstream 217049 6689915 ~ 6691084 (+)
AMCG00019178 NA coding downstream 442222 7359603 ~ 7379672 (+)
AMCG00019180 NA coding downstream 466058 7383439 ~ 7394256 (+)
AMCG00019181 gbx1 coding downstream 482874 7400255 ~ 7403144 (+)
AMCG00019187 tmub1,LOC105023792,LOC102788489 coding downstream 779472 7696853 ~ 7701770 (+)
AMCG00019190 NA coding downstream 794274 7711655 ~ 7712858 (+)
G31947 NA non-coding upstream 88098 6819765 ~ 6820035 (+)
G31930 NA non-coding upstream 215853 6691722 ~ 6692280 (+)
G31915 NA non-coding upstream 229745 6678165 ~ 6678388 (+)
G31914 NA non-coding upstream 234956 6672898 ~ 6673177 (+)
G31894 myl13,myl3,LOC107660402,LOC107567878,LOC107711693,LOC107593749 non-coding upstream 471426 6434199 ~ 6436707 (+)
G31992 NA non-coding downstream 307251 7224632 ~ 7224997 (+)
G32010 agap3,LOC107383869 non-coding downstream 514299 7431680 ~ 7431944 (+)
G32048 NA non-coding downstream 703123 7620504 ~ 7620812 (+)
G32113 NA non-coding downstream 1254264 8171645 ~ 8171861 (+)
G32235 NA non-coding downstream 1977858 8895239 ~ 8933746 (+)
AMCG00019154 ghrhrb,LOC107704523,LOC106560417,LOC107717144,LOC107556991 other upstream 968536 5930704 ~ 5939597 (+)
AMCG00019111 phlpp1,LOC106599727,LOC103135813,LOC101477421,LOC106925929,LOC102225687,LOC103479552 other upstream 2539930 4319596 ~ 4368203 (+)
AMCG00019100 crem,crema,LOC105019435,LOC106578540,LOC108428923,LOC103396770 other upstream 3697243 3190612 ~ 3210890 (+)
AMCG00019096 LOC107727496 other upstream 3807962 3094452 ~ 3100171 (+)
AMCG00019089 NA other upstream 4290081 2520104 ~ 2618052 (+)
G32005 NA other downstream 503120 7420501 ~ 7421083 (+)
G32130 itgb1a,LOC107566918,LOC107713907,LOC107734314,LOC107565694,LOC107653806,LOC106590025,LOC104924090,LOC106578567,LOC105019428 other downstream 1428074 8345455 ~ 8384592 (+)
G32286 NA other downstream 2343993 9261374 ~ 9539211 (+)
AMCG00019215 mpp7,LOC107657298,LOC107584397,LOC107721969,LOC104966300 other downstream 2412098 9329479 ~ 9348819 (+)
G32293 armc4 other downstream 2452517 9369898 ~ 9628662 (+)

Expression



Co-expression Network