AMCG00019289 (mib1)


Basic Information

Item Value
gene id AMCG00019289
gene name mib1
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030124.1
NCBI id CM030124.1
chromosome length 51038645
location 12641964 ~ 12671029 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00019289
ATGACCACCGGCAGAAATAACAGGATTATGATGGAAGGCGTGGGGGCGCGGGTGGTGCGGGGTCCGGACTGGAAGTGGGGCAAACAGGACGGCGGAGAGGGACACGTCGGCACCGTCAGGAGTTTCGAGAGTCCGGAGGAAGTGGTGGTGGTCTGGGATAACGGGACGGCGGCCAACTACCGCTGCTCCGGCGCCTATGACGTCAGGATCTTCGACAGTGCACCCACAGGTATCAAACACGATGGGACCATGTGCGACACATGCCGTCAGCAGCCTATAATCGGAATCCGCTGGAAGTGTGCGGAATGCACGAACTACGACCTGTGCACGACGTGTTACCATGGAGACAAGCATCATCTGCGACATCGCTTCTACAGAATCACCACACCGGGGAGTGAGAGggttCTGCTGGAGTCTCGCCGCAAATCCAAAAAGATCACGGCCCGGGGGATCTTCACGGGTGGGCGAGTGGTGCGAGGCGTGGACTGGCAGTGGGAGGACCAGGATGGCGGCAATGGCAGGAGGGGCAAGGTGACGGAGATCCAAGACTGGAGCGCGGCCAGCCCACACAGTGCAGCATATGTGCTCTGGGACAATGGAGCCAAGAACCTGTACAGAGTGGGCTTTGAGGGAATGTCTGATTTGAAATGCGTTCAGGATGCCAAGGGGGGATCCTTTTATCGAGACCATTGCCCTGTTCTAGGCGAGCAGAACGGGAACCGAAACCCCGGCGGGCTGCAGATTGGAGACCTGGTGAACATCGACCTGGACCTGGAGATCGTGCAGTCCCTGCAGCACGGCCACGGGGGCTGGACCGATGGCATGTTTGAGACCCTCACCACTACTGGCACTGTCTGTGGCATCGATGAAGACCATGATATTGTGGTGCAGTACCCCAGTGGGAACCGCTGGACATTTAACCCTGCGGTCCTGACGAAGGCAAACGTGGTCCGCAGCGGAGATGCGGCGGCCGGGGCGGAGGGCGGGACCTCTCAGTTCATGGTGGGCGACCTTGTACAGATCTGCTACGACATTGACCGTATCAAGCTGCTGCAGAGAGGCCACGGGGAGTGGGCAGAAGCCATGCTGCCGACTTTAGGGAAGGTAGGTCGTGTCCAGCAGATCTACTCAGACAGCGACCTCAAGGTGGAGGTCTGTGGGACGTCCTGGACTTACAACCCAGCGGCCGTCACAAAAGTGGCCCCCGCTGGCTCTACTGTTACCAATGCCTCTGGAGAGCGTCTTTCCCAGCTGTTAAAGAAGCTTTTTGAAACCCAGGAGTCAGGTGACATCAATGAAGAGCTGGTCAAAGCGGCAGCCAATGGGGATCTCGCTAAAGTGGAGGACATTCTTAAGCGGCCTGACGTTGACgttaATGGACAGTGTGCTGGGCATACAGCTATGCAAGCAGCCAGTCAAAATGGACATGTGGATGTGCTAAAATTACTTCTCAAACATAGTGTTGACTTGGAAGCAGAGGACAAAGACGGAGACAGGGCTGTGCACCACGCAGCCTTCGGAGACGAGGGCTCGGTTATTGAGGTTTTGCACAGAGGCGGTGCGGATCTGAATGCTCGAAACAAGCGCAGACAGACCCCCTTGCACATTGCAGTAAATAAAGGGCACCTGCAAGTGGTTAAGACTTTGCTGGACTTTGGCTGCCACCCCAGTCTTCAGGACTCTGAAGGAGACACCCCTCTGCATGACGCCATAAGCAAGAAGCGAGACGACATGCTGTCTGTGCTGCTGGAAGCCGGAGCTGATGTCACCATCACCAACAACAATGGCTTCAACGCACTCCATCATGCCGCCCTGCGAGGGAACCCCAGGTACTGCGCAGTCTCATTGAGCCCCCTCTTCACAGTGCACCCTGCAGAGGGTGCTCTTTCTGGGTTTTGA

Function

symbol description
mib1 Enables identical protein binding activity and ubiquitin-protein transferase activity. Acts upstream of or within several processes, including animal organ development; nervous system development; and tube morphogenesis. Located in endocytic vesicle and perinuclear region of cytoplasm. Part of protein-containing complex. Is expressed in nervous system; neural tube; and pectoral fin. Used to study epilepsy. Human ortholog(s) of this gene implicated in left ventricular noncompaction. Orthologous to human MIB1 (MIB E3 ubiquitin protein ligase 1).

NR:

description
E3 ubiquitin-protein ligase mib1 isoform X5

GO:

id name namespace
GO:0021521 ventral spinal cord interneuron specification biological_process
GO:0045747 positive regulation of Notch signaling pathway biological_process
GO:0007507 heart development biological_process
GO:0060113 inner ear receptor cell differentiation biological_process
GO:0001756 somitogenesis biological_process
GO:0048793 pronephros development biological_process
GO:0071599 otic vesicle development biological_process
GO:0061195 taste bud formation biological_process
GO:0009880 embryonic pattern specification biological_process
GO:0048546 digestive tract morphogenesis biological_process
GO:0002090 regulation of receptor internalization biological_process
GO:0021654 rhombomere boundary formation biological_process
GO:0031076 embryonic camera-type eye development biological_process
GO:0060218 hematopoietic stem cell differentiation biological_process
GO:0001570 vasculogenesis biological_process
GO:0008284 positive regulation of cell population proliferation biological_process
GO:0051865 protein autoubiquitination biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0001885 endothelial cell development biological_process
GO:0021986 habenula development biological_process
GO:0045664 regulation of neuron differentiation biological_process
GO:0030318 melanocyte differentiation biological_process
GO:0045685 regulation of glial cell differentiation biological_process
GO:0021508 floor plate formation biological_process
GO:0021519 spinal cord association neuron specification biological_process
GO:0021520 spinal cord motor neuron cell fate specification biological_process
GO:0048471 perinuclear region of cytoplasm cellular_component
GO:0030139 endocytic vesicle cellular_component
GO:0000151 ubiquitin ligase complex cellular_component
GO:0005886 plasma membrane cellular_component
GO:0004842 ubiquitin-protein transferase activity molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K10645 MIB; E3 ubiquitin-protein ligase mind-bomb

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00019289 True 1899 mRNA 0.57 12 12641964 12671029

Neighbor

gene id symbol gene type direction distance location
AMCG00019290 NA coding upstream 43447 12572727 ~ 12598517 (+)
AMCG00019280 thoc1,LOC106600433 coding upstream 187592 12446933 ~ 12454372 (+)
AMCG00019283 impa2 coding upstream 201113 12430978 ~ 12440851 (+)
AMCG00019282 gnal,LOC103396682,LOC106520735 coding upstream 229691 12407378 ~ 12412273 (+)
AMCG00019281 gnal,LOC107554377,LOC107732066,LOC107667176,LOC106520735 coding upstream 316126 12324271 ~ 12325838 (+)
AMCG00019293 mib1,LOC106600429,LOC107747519,LOC107691191,LOC107550435,LOC107681781 coding downstream 37536 12708565 ~ 12722210 (+)
AMCG00019295 NA coding downstream 96925 12767954 ~ 12778615 (+)
AMCG00019297 rbbp8,LOC107732059 coding downstream 187951 12858980 ~ 12873054 (+)
AMCG00019300 NA coding downstream 210952 12881981 ~ 12882526 (+)
AMCG00019296 cables1 coding downstream 234445 12905474 ~ 12916716 (+)
G32893 NA non-coding upstream 28038 12613285 ~ 12613926 (+)
G32892 NA non-coding upstream 29431 12609401 ~ 12612533 (+)
G32778 NA non-coding upstream 640800 12000963 ~ 12001164 (+)
G32674 NA non-coding upstream 1004084 11632358 ~ 11637880 (+)
G32671 NA non-coding upstream 1193713 11377956 ~ 11448251 (+)
G33075 LOC104962440 non-coding downstream 640385 13311414 ~ 13311742 (+)
G33093 NA non-coding downstream 962673 13633702 ~ 13638171 (+)
G33141 cdh2,LOC102201754,LOC101473079,LOC102787731,LOC103371087 non-coding downstream 1481773 14152802 ~ 14160703 (+)
G33153 NA non-coding downstream 1614536 14285565 ~ 14286016 (+)
G33161 NA non-coding downstream 1820863 14491892 ~ 14492206 (+)
G32539 NA other upstream 2232467 10404639 ~ 10409497 (+)
G32293 armc4 other upstream 3013302 9369898 ~ 9628662 (+)
G32286 NA other upstream 3102753 9261374 ~ 9539211 (+)
AMCG00019215 mpp7,LOC107657298,LOC107584397,LOC107721969,LOC104966300 other upstream 3293145 9329479 ~ 9348819 (+)
G32130 itgb1a,LOC107566918,LOC107713907,LOC107734314,LOC107565694,LOC107653806,LOC106590025,LOC104924090,LOC106578567,LOC105019428 other upstream 4257372 8345455 ~ 8384592 (+)
G33159 LOC103376870 other downstream 1768224 14439253 ~ 14486706 (+)
G33283 NA other downstream 2493319 15164348 ~ 15169841 (+)
AMCG00019345 NA other downstream 2883790 15554819 ~ 15626955 (+)
G33406 NA other downstream 3372913 16043942 ~ 16081943 (+)
AMCG00019376 NA other downstream 4778291 17449320 ~ 17452659 (+)

Expression


Co-expression Network