AMCG00019571 (irf4a,irf4,LOC108267998,LOC107565529)


Basic Information

Item Value
gene id AMCG00019571
gene name irf4a,irf4,LOC108267998,LOC107565529
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030124.1
NCBI id CM030124.1
chromosome length 51038645
location 30448193 ~ 30462200 (-)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00019571
ATTGCAAAGAATAAGAATATACCCATTTTAAAAAAGTCAGCTGTCAACAGAAATCCCAGCTGCCTATTTGTATGCTTTTTGCAGTAACTGCCACTCAGAAGTATATTTCTAAAGCACGGCCTGTAGCTCCTCTTCATTTGATGCTATACTATGAAGCAgatctagttttttttttttgctttagtAGGATAACAACTGAAATCATAAATAAAGAGATGAACTTAGACAGTGACTGCAGCATGTCAGTCAGTTGTGGCAATGGGAAGCTTAGGCAGTGGCTGATTGATCAGATTGACAGCGGAAAGTACCCCGGCTTGGTTTGGGAGAATGACGAGAAAACCATTTTCAGGATCCCCTGGAAACATGCGGGCAAACAGGACTACAACCGGGACGAGGACGCCGCGCTGTTCAAGgCTTGGGCACTTTTCAAGGGGAAATTCAGAGAGGGGATTGATAAACCGGATCCCCCAACTTGGAAAACAAGATTGCGATGTGCCTTGAACAAAAGCAATGACTTTGAGGAACTGGTGGAGAGAAGTCAGCTGGACATTTCAGATCCATATAAGgaGCAAAGCAGATTAGTATGGAGGAGTCTCCTTCACATATCAACACACTTGGTTATATGCATCCTTCTTTCCCCCCTCTACAATCTCAGGTACCCAACTACATGGTGCCTCATGAGCGCAACTGGAGGGATTATGTTCCAGAGCAGCCTCACCCAGACCTACCTTATGGCCAGTGTCCATATCCTCCGAGAAACCTCCCTTGGCAAGGAGCTGCATGTGAGAATGCCTCCGGGATTTTCACTCGACCCCAGCATGAGGTCGGCCGAGGCTGTGGCCTTAACAGACTGCCGTTTACACATCTGCCTGTACTACCGCGAGTCCCTTGTAAAGGAGGTGACCACAACGAGTCCTGAGGGATGCAGGATATCGTCCGCTTCAAGCATCGATGACAAGCTGTATGGCCACAGCAACATGGATCAGGTGATCTTCCCCTACCCTTTCCCACAATCTCAGAGGAAAGGTGTGGAGAAGGTGCCCAATGCCCTCGAGAGAGGAGTATTGCTGTGGATGGCGCCAGACGGGCTGTACGCTAAAAGACTCTGCCAAAGCAGGATCTTCTGGGAAGGACCCCTGGCGCCATACACCGATAAACCCAACAAACTGGAGAAAGACCATACCTGCAAGCTGTTTGACACACAGCAGTTTCTCACAGAGCTCCAGGGCTATGCCCACCATGGCCGCTCCATTCCCAGGTTCcagattgtgttgtgttttggcgACGAATACCCCGACCCTCAGAGGCAGAGGAAGATGATTACAGctcatGTGGAACCCATGTTTGCCAGACAACTTTTCTACTTTGCGCAGCCCAACAGCAGTCACTTCCTTCGTGGATATGAGCTTCCTGAGCATGTTTCTCCCAGCGAGGAATACCAGAGGGCAATCCACCACAGCTCCATTCCCGAGTGACACGGCATCCTCCTCGAACcttgaacatgtttttgtgttttgaatttttCTCTGCGGAAATTAACACGGTTGATGATATTTCAGTGGACAGTGAGATCTGTGCGGGACAACGTGAGATTGGAAAGGACTTTTTCTGTAACAGGAAAACTGGAGCCCTGAAACAAGACAAAACTGACAAAGCAAAGGACTTTTTGCAGCTAAATCCTTACCTGTCATGTCAGGAGAACTGTTACCTGGACTGATGGGACAGTGAGCAAGATGCATGTGCTATCCCTCTTTCTCAagctatgaaaacatttttctcttcAACTAATCGAGGGAAGTCTATTGTGGGGTACAGTATCctaatgtgttcatttttacatacacacacacacacacacactatacatatgtgtgtgtgtgtgtgcgtgtgtgtgtgtgttttgtttttaataaatgtaattgttttacttttttgttttaatcctcaGGGTGCTTTTCACTGTATATGCAAACTAACAAAGTCATAGGTATGTAGGTGAGTGATAGAAAGTCCGGCATTCAGATAGGTAGGTAGATAGAAGGAAGTCTCTAGATATGATAAGTCTGCCTTACTCTTGTCCTTCATCAGCACTGATGATATGAAAAAAGGCTCAACTGATTTaatgaatgtgtatgtgttacgttttatttaaaatttatttttggatttagtttttttattgatgtttgtACATTGTGTCTGGTAGGTGACTGTTCTTTATGCCTTCTGTAAGCTCTGATGTAAATACTTTTTAGCCTAATTTGAATAGGTTGTTGAAAGACcctaaaaatagttttgaatttattttgacatgaaGTAAAATGGTGAGCCACACTCTATTAATATCTGCGTTGTCACATCCTTCAGCAGCACAGAACTGGCGAGTAACATTGACAAGCGTGCGCACTAAATTACACTTTCACTCTGGGCTAATTTCTGTCATATGAACAAACTGCACTTCATCACAATTTATCAGCATGTTTGATCAAGGTCACATTATATCTCGTCTGTGTGTCTCACATTGGGGGTTGTGCTGGCTTCAAGGGGTCCCAACAAGAGCTATGCTTTTACGGTAAACTGAAGTAACCTTCCTCACAATCAACAGGGTGGGCTACCCACATAGCTTCCTGGCATGTGTTGAAGCATGATGGGAAAATGGCAGATTCAGGTAACAGCCCACATGCTACTGTCTCAGAGTCCTTACCGTATAGCCACAATGACatgagagggaggaggaggggaaagacCCTGATGTGAGTTACAGAAAGGCCCTTTCTGTCAATGGCCgtgttttacagtgtttgtAAACAAACGGCATCTCTGACAAATTTACGAGCAATCAGAAATGATGGGCTTTTCCCTTATCAGCATGCGGTCTGCTGTGGTAGGCAGAGTGGACTCTAATCTAGCCTGCTAAGCACAAAAGATAGTTTAGCGTGTTAAACtagggcagtagtgtggagtagtggtcagggctctggactttgGAGCAGGGGGTTGTgtggggacactgctgtagattgctccagtaaatgcccagctgtataaatgggtaaaatgtaaaaataatgtgatataatgtaacaattgttagtcaccctggataagggtgtctgctaagaaaattagtaataatgataataataaactgaatttcACATATTCTGATTTTCTAATCATTGGCATTatggcagtgtggagtagtggtttggGCTTGTGAATGGAGGGGCTTCTGTAAAAGTAAATGACAGAATTCAAGAG

Function

symbol description
irf4a Enables DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within lymphoid lineage cell migration into thymus; lymphoid progenitor cell differentiation; and negative regulation of myeloid cell differentiation. Located in chromatin and nucleus. Is expressed in several structures, including hematopoietic multipotent progenitor cell; hematopoietic system; liver; pleuroperitoneal region; and thymus. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; anaplastic large cell lymphoma; chronic lymphocytic leukemia; multiple myeloma; and peripheral T-cell lymphoma. Orthologous to human IRF4 (interferon regulatory factor 4).
irf4 Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of cytokine production and positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. Implicated in acute lymphoblastic leukemia; anaplastic large cell lymphoma; chronic lymphocytic leukemia; multiple myeloma; and peripheral T-cell lymphoma. Biomarker of dilated cardiomyopathy and hematologic cancer (multiple).

NR:

description
PREDICTED: interferon regulatory factor 4-like

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K09445 IRF4; interferon regulatory factor 4

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00019571 True 3261 mRNA 0.44 9 30448193 30462200

Neighbor

gene id symbol gene type direction distance location
AMCG00019566 NA coding downstream 263686 30183515 ~ 30184507 (-)
AMCG00019563 foxf2,LOC102792585 coding downstream 275913 30167515 ~ 30172280 (-)
AMCG00019564 foxc1,foxc1a,LOC103370816,LOC104941097,LOC106532673 coding downstream 310032 30136731 ~ 30138161 (-)
AMCG00019555 wrnip1,LOC103135799,LOC106941779 coding downstream 662951 29773685 ~ 29785242 (-)
AMCG00019557 NA coding downstream 681587 29761329 ~ 29766606 (-)
AMCG00019572 NA coding upstream 11246 30473446 ~ 30477047 (-)
AMCG00019573 tbb2c,LOC107393497,LOC105029894,LOC105891054,LOC105023713,LOC106593669,LOC106575097 coding upstream 103836 30566036 ~ 30568189 (-)
AMCG00019575 NA coding upstream 114977 30577177 ~ 30591280 (-)
AMCG00019576 NA coding upstream 166522 30628722 ~ 30629555 (-)
AMCG00019581 NA coding upstream 392738 30854938 ~ 30857867 (-)
G35190 NA non-coding downstream 5603 30412198 ~ 30442590 (-)
G35157 gmds,LOC107721371,LOC107556133 non-coding downstream 321863 30081650 ~ 30126330 (-)
G35145 NA non-coding downstream 600335 29847644 ~ 29847858 (-)
G35144 NA non-coding downstream 619543 29826657 ~ 29828650 (-)
G35129 NA non-coding downstream 676001 29771586 ~ 29772192 (-)
G35214 NA non-coding upstream 44870 30507070 ~ 30520464 (-)
G35243 NA non-coding upstream 130741 30592941 ~ 30674883 (-)
G35304 NA non-coding upstream 574924 31037124 ~ 31037337 (-)
G35397 mak,ick non-coding upstream 945782 31407982 ~ 31410657 (-)
G35448 NA non-coding upstream 1284425 31746625 ~ 31746866 (-)
G35101 NA other downstream 762891 29679229 ~ 29685302 (-)
AMCG00019554 zgc:56676,eif1b,LOC106578512,LOC105910901,LOC107657782,LOC105027100,LOC107396491 other downstream 802230 29638566 ~ 29645963 (-)
AMCG00019556 NA other downstream 898031 29535744 ~ 29550162 (-)
G35067 NA other downstream 926209 29517996 ~ 29521984 (-)
AMCG00019500 pign other downstream 6353529 24052011 ~ 24094664 (-)
AMCG00019597 NA other upstream 959829 31422029 ~ 31427583 (-)
G35476 LOC107575789 other upstream 1759864 32222064 ~ 32233398 (-)
AMCG00019645 NA other upstream 4048533 34510733 ~ 34522270 (-)
G35867 NA other upstream 4592819 35055019 ~ 35055444 (-)
AMCG00019665 NA other upstream 5472596 35934796 ~ 35981536 (-)

Expression


Co-expression Network