XLOC_000062 (atic)



Basic Information


Item Value
gene id XLOC_000062
gene name atic
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 5437390 ~ 5504130 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00000120
ACGGTTAAACGGTGAAGAAAACTGAAGACGCGGTTTGaggcTGACCTTCACAAATACAGTTTCTTCAGTGACCACCTCCTGAAACGTCTACAAAACAATCTGCTCAAACCTCTCCATGCTGTTACTTGAAGCTCCTCTATGTCGTCCTCCGAGAAGGGGCTGTCGGGATGATATAACGCAGCGGTGTGGTGCAGAAAGTCTGTGGATCGGGACACGCTGAGGCTGTTGTTGATGAACTTGTGTTGTCCGTCCTCTTCGTCCTCTTCGTCTTCATCtatctcctcttcctcctcctcctcttcctcctgttCCTCCACACTGGGAGCTGCTGGAGCGCGTCTGCTGTCCCGTCCGCTGGGTTTGGTTCCTCCACGCTGCCGCTCCACCTCCACCTGCGCCGCCTGCTCTTTAGCTTTACGACTGCGCTTCCACTTCATCCGCCGGTTCTGGAACCAGATCTTCACCTGGTGtgggagaaacacacacacatgcatggacACAAGTCTTTTTTAGAACTTCTAATGTTCTGCTGATCTCAAAGAAGACGCAAAGAGGACAAAGCGAGGAGCTTCTGAAGGCATTGGGAGTTCATGTTGTGAAAATGCAAGGTGTGCGACAGGCGCCATCTTTCGGTGTGTTTGCAAAGCATTGCTGAGCGTTTCGGATAAGACTGGACTGGTGGAGTTCGCCAGGCGTCTGGTGTCAGTGGGTCTGTCATTAGTGGCATCAGGAGGAAC
>TCONS_00000121
aggcTGACCTTCACAAATACAGTTTCTTCAGTGACCACCTCCTGAAACGTCTACAAAACAATCTGCTCAAACCTCTCCATGCTGTTACTTGAAGCTCCTCTATGTCGTCCTCCGAGAAGGGGCTGTCGGGATGATATAACGCAGCGGTGTGGTGCAGAAAGTCTGTGGATCGGGACACGCTGAGGCTGTTGTTGATGAACTTGTGTTGTCCGTCCTCTTCGTCCTCTTCGTCTTCATCtatctcctcttcctcctcctcctcttcctcctgttCCTCCACACTGGGAGCTGCTGGAGCGCGTCTGCTGTCCCGTCCGCTGGGTTTGGTTCCTCCACGCTGCCGCTCCACCTCCACCTGCGCCGCCTGCTCTTTAGCTTTACGACTGCGCTTCCACTTCATCCGCCGGTTCTGGAACCAGATCTTCACCTGGTGtgggagaaacacacacacatgcatggacACAAGGTGATCAGCAATAATAGATGCATTCTgcttcactgaaaaaaatgattcattgggtttacttaatttttttaagctagagtaagtggttgcaaacaatttacatgggctgaatttattcttttttttattctactcattaaaataaacaaatgaaa
>TCONS_00000122
GCGGATAAAACTATTGCATCCACGTGTTTTGATTAACACCGCGCGCTTCACGAGACGCTCCAGCACAAATCTCTGATTTCCTCCGCTTTCTCTGCAGCATGGCATCTGAAATAGCATTGCTGAGCGTTTCGGATAAGACTGGACTGGTGGAGTTCGCCAGGCGTCTGGTGTCAGTGGGTCTGTCATTAGTGGCATCAGGAGGAACCGCCAAAACACTCAGAGATGCTGGACTTGCAGTCAGGGATGTATCCGAGATCACTGGATTCCCTGAGATGCTCGGAGGCAGAGTTAAAACCCTTCATCCAGCTGTCCACGGTGGTATTTTGGCCAGACAAACTCCATCTGATAATGCTGATATGGAAAAACTTGGGTTTAGTCTTGTCAGAGTGGCCGTGTGCAACCTTTACCCGTTTGTGAAGACCGTTTCATCCCCTGGTGTGACTGTGGAAGACGCTGTTGAGCAGATTGACATCGGTGGTGTTACGCTTCTTCGAGCGGCAGCTAAGAATCACGCTAGAGTCACCGTCGTCTGCGATCCATCCGACTACAATGTTGTGGCCAAGGAAATGGAGACCTCTGAAATCCACGACACCACAATGGAAACCCGCAAAACTCTCGCGCTCAAGGCCTTCACGCACACCGCTCAGTACGACGAGGCCATCTCTGATTACTTCAGACGTGAATACAGTCGAGGAGTTTCCCAGCTTCCTCTGCGTTACGGGATGAACCCACATCAAGCACCAGCTCAGCTCTACACTACACGACCAGCACTTCCGCTCACAGTGCTGAATGGATCTCCTGGCTTCATTAATCTGTGTGATGCTCTGAACGCCTGGCAGCTGGTCAGAGAGTTGAGGAAGGCTCTCGGTTTGCCAGCCGCCACTTCATTTAAACACGTCAGTCCTGCAGGAGCTGCTGTCGGCGTCCCGTTGAGTGAAGACGAGGCCAAAGTGTGTATGGTGAATGACATGCTGCAGGATCTCACTCCTCTCGCCACTGCGTACGCCAGAGCCAGAGGATCTGACAGAATGTCCTCTTTTGGAGACTTCATCGCTTTGTCTGATGTCTGTGATGTTCCCACTGCCAAGATCATCTCCAGAGAGGTGTCTGATGGTATTGTTGCTCCTGGTTATGAAGAGGATGCGCTGCGAATTCTGTCCAAAAAGAAGAATGGAAACTATTGTGTTCTTAAGatgGATCCTGAATATGAACCTGATGAGGAAGAGGTGAGGGTGCTGTTTGGTTTACATCTCAAACAGAAGAGGAATGGAGCAGTCATTGATAAAGAGCTCTTCAGCAACATTGTGTCAAAGGGAAAGCTCTCTGAGAGTGCTCTGCGAGACCTCATCGTTGCCTCCATCGCTGTAAAGTACACCCAGTCTAACTCTGTGTGTTATGCTAAGGATGGGCAGGTGATTGGCATCGGAGCTGGGCAGCAGTCTCGTATCCACTGCACCCGGCTGGCAGGAGACAAGGCTGATAACTGGTGGCTCAGGCACCATCCAGGAGTGCTCAGTATGAGGTTCCGCGGCGGAGTGAAGCGTGCAGAGATGGCTAATGCTATTGATCTGTATGTCAGCGGCACAGTTGGAGAGGGACCAGATAAAGAGGTCTGGAAGGGTCTTTTTGAGGAGGTTCCTGAGCCTCTGTCAGAGGTGGAGAAGAAGAATTGGATCAGTTCTCTGCAGGCTGTGGCCCTCAGCTCTGATGCTTTCTTCCCCTTTAGGGACAATGTTGACCGTGCCAAACAGAGCGGTGTGGAGTATATCGCTGCTCCGTCTGGCTCTACTGCTGATGAAGTGGTTGTCAAGGCCTGCAATGAGCTGGGAATTACCCTGGTACACACCAACATTCGTCTCTTCCATCACTGAAAATCACTACAAAACTTCAGCTGAATTCAGATATGCTACCACAAGTATACAGCTACTTCAGGCGTCTTTCTCTAGATGTGCATGCCCGCAGTGAGCTAGGAATTACCCTGCTAAACACCAACATCCGTCCCTTTCATCAGTGAAAAGCATCTTATAGAATACTAATACACAATATATCATACAAATATACAGCTACTGTAGGTGTTTTCTCTGTAGATGTACACTGGAGTTTCAAGTTGCTACCTAGGTTTCATGATTCAACACAGAGTAGTAGTAAATCTCTCTACTTTCCAGTGTTAAGTCTAATGTTTAACTCCGAGTACATGGCACCTAACAGATTTTAAACATAGTTACTGTGGGAATATTATTCATGCATGACTTTGTGATACTGATGCATTCAGAATAATGTAATCCactcatttttcattttcatcttaacATACTACTTAGCATTATTTCAGCCGTGTGGTCCCTGTTTAAGATGCAACTGGGGTTGGAAAATGGTATCTAATATGAAATGGTTTCCATACACTTCCTGAAACATTCCATTGTGCTGCCTTTAGCGTCTCGTGagcattgcaaaataaaaaaacacagcaaatgtaa
>TCONS_00000123
GCTTTCAGGAGCTGCTGTCGGCGTCCCGTTGAGTGAAGACGAGGCCAAAGTGTGTATGGTGAATGACATGCTGCAGGATCTCACTCCTCTCGCCACTGCGTACGCCAGAGCCAGAGGATCTGACAGAATGTCCTCTTTTGGAGACTTCATCGCTTTGTCTGATGTCTGTGATGTTCCCACTGCCAAGATCATCTCCAGAGAGGTGTCTGATGGTATTGTTGCTCCTGGTTATGAAGAGGATGCGCTGCGAATTCTGTCCAAAAAGAAGAATGGAAACTATTGTGTTCTTAAGatgGATCCTGAATATGAACCTGATGAGGAAGAGGTGAGGGTGCTGTTTGGTTTACATCTCAAACAGAAGAGGAATGGAGCAGTCATTGATAAAGAGCTCTTCAGCAACATTGTGTCAAAGGGAAAGCTCTCTGAGAGTGCTCTGCGAGACCTCATCGTTGCCTCCATCGCTGTAAAGTACACCCAGTCTAACTCTGTGTGTTATGCTAAGGATGGGCAGGTGATTGGCATCGGAGCTGGGCAGCAGTCTCGTATCCACTGCACCCGGCTGGCAGGAGACAAGGCTGATAACTGGTGGCTCAGGCACCATCCAGGAGTGCTCAGTATGAGGTTCCGCGGCGGAGTGAAGCGTGCAGAGATGGCTAATGCTATTGATCTGTATGTCAGCGGCACAGTTGGAGAGGGACCAGATAAAGAGGTCTGGAAGGGTCTTTTTGAGGAGGTTCCTGAGCCTCTGTCAGAGGTGGAGAAGAAGAATTGGATCAGTTCTCTG

Function


symbol description
atic Predicted to enable IMP cyclohydrolase activity and phosphoribosylaminoimidazolecarboxamide formyltransferase activity. Predicted to be involved in 'de novo' IMP biosynthetic process. Predicted to act upstream of or within purine nucleotide biosynthetic process. Predicted to be active in cytosol. Is expressed in several structures, including digestive system; immature eye; nervous system; neural crest; and yolk. Human ortholog(s) of this gene implicated in purine-pyrimidine metabolic disorder. Orthologous to human ATIC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase).

GO:

id name namespace
GO:0006164 purine nucleotide biosynthetic process biological_process
GO:0006189 'de novo' IMP biosynthetic process biological_process
GO:0005829 cytosol cellular_component
GO:0003937 IMP cyclohydrolase activity molecular_function
GO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity molecular_function
GO:0003824 catalytic activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-011212-4 Predicted to enable IMP cyclohydrolase activity and phosphoribosylaminoimidazolecarboxamide formyltransferase activity. Predicted to be involved in 'de novo' IMP biosynthetic process. Predicted to act upstream of or within purine nucleotide biosynthetic process. Predicted to be active in cytosol. Is expressed in several structures, including digestive system; immature eye; nervous system; neural crest; and yolk. Human ortholog(s) of this gene implicated in purine-pyrimidine metabolic disorder. Orthologous to human ATIC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase).

Ensembl:

ensembl_id ENSDARG00000016706

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00000120 False 737 processed_transcript 0.52 5 5437390 5487162
TCONS_00000121 False 621 processed_transcript 0.48 2 5438743 5450444
TCONS_00000122 False 2477 mRNA 0.48 15 5485799 5504130
TCONS_00000123 True 784 processed_transcript 0.50 7 5497285 5502084

Neighbor


gene id symbol gene type direction distance location
XLOC_000061 stk16 coding upstream 3129 5422439 ~ 5434261 (+)
XLOC_000060 tuba8l2 coding upstream 18274 5402476 ~ 5419116 (+)
XLOC_000059 NA coding upstream 123795 5311479 ~ 5313595 (+)
XLOC_000058 spry2 coding upstream 159807 5273481 ~ 5277583 (+)
XLOC_000057 NA coding upstream 407235 4901460 ~ 5030155 (+)
XLOC_000063 cpo coding downstream 72021 5576151 ~ 5587575 (+)
XLOC_000064 NA coding downstream 202840 5706970 ~ 5728684 (+)
XLOC_000065 NA coding downstream 290883 5795013 ~ 5799092 (+)
XLOC_000066 abcb6a coding downstream 631046 6135176 ~ 6158609 (+)
XLOC_000067 cnppd1 coding downstream 657800 6161930 ~ 6185532 (+)
XLOC_000056 FO744838.1 non-coding upstream 756913 4598060 ~ 4680477 (+)
XLOC_000054 CABZ01063288.1 non-coding upstream 1677356 3759924 ~ 3760034 (+)
XLOC_000053 NA non-coding upstream 1716787 3718666 ~ 3720603 (+)
XLOC_000072 NA non-coding downstream 875748 6379878 ~ 6554470 (+)
XLOC_000073 NA non-coding downstream 894080 6398210 ~ 6403223 (+)
XLOC_000076 NA non-coding downstream 1160903 6665033 ~ 6668339 (+)

Expression



Co-expression Network