XLOC_000641 (mdh1aa)


Basic Information

Item Value
gene id XLOC_000641
gene name mdh1aa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 50968908 ~ 50990889 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001087
GAAACCTGAAGCTCTATGAGGGATGTTTTATCCTCTCAGCTCGGCGTTGCAGCATCAATCCCACACTGACGTCACCCCCCAAATTTCGCATCCCGCAAtagctcattcatttatttagcctTGTGATCAGAAATGGCGGAAAGATTACTCGATGTCGAGCTATTTATGTCTCCTAAAGCTCATTAGGTGTGAACGGCTGACGGTGAAACGAGGAAATTAAGCGGCTCTTGCGCGTCTCCGGAGCTCGGGTTACCGCGCGCACCTCTCTGCGTCTGAGCGCGTCCCAAAACACTGCATTCGAGGGGGGAAACACACTCCGTCGGACACTTCGAGGGACACACTGCTTGAAAATGTTGACCCTGCTGTCGGCTATGTACTTGGTGGTGCGCACGGCTTCGGCGCAGGCCGAACCGATCCGTGTTTTGGTGACTGGCGCCGCCGGACAGATCGCCTATTCTCTGCTCTACAGCATCGCTAAAGGAGATGTGTTCGGCAAGGACCAGCCAATCATCTTGGTGCTCCTGGATATCACTCCCATGCTGCCGGTGCTGGATGGAGTCGTCATGGAGCTGCAGGATTGTGCTCTTCCTCTTCTGAGAGAGGTGATTCCCACTGATAAGGTTGAGGTGGGCTTCAAGGATCTTGATGCTGCCATCTTGGTGGGCTCTATGCCCAGAAAAGAGGGCATG
>TCONS_00001088
GAAACCTGAAGCTCTATGAGGGATGTTTTATCCTCTCAGCTCGGCGTTGCAGCATCAATCCCACACTGACGTCACCCCCCAAATTTCGCATCCCGCAAtagctcattcatttatttagcctTGTGATCAGAAATGGCGGAAAGATTACTCGATGTCGAGCTATTTATGTCTCCTAAAGCTCATTAGGTGTGAACGGCTGACGGTGAAACGAGGAAATTAAGCGGCTCTTGCGCGTCTCCGGAGCTCGGGTTACCGCGCGCACCTCTCTGCGTCTGAGCGCGTCCCAAAACACTGCATTCGAGGGGGGAAACACACTCCGTCGGACACTTCGAGGGACACACTGCTTGAAAATGTTGACCCTGCTGTCGGCTATGTACTTGGTGGTGCGCACGGCTTCGGCGCAGGCCGAACCGATCCGTGTTTTGGTGACTGGCGCCGCCGGACAGATCGCCTATTCTCTGCTCTACAGCATCGCTAAAGGAGATGTGTTCGGCAAGGACCAGCCAATCATCTTGGTGCTCCTGGATATCACTCCCATGCTGCCGGTGCTGGATGGAGTCGTCATGGAGCTGCAGGATTGTGCTCTTCCTCTTCTGAGAGAGGTGATTCCCACTGATAAGGTTGAGGTGGGCTTCAAGGATCTTGATGCTGCCATCTTGGTGGGCTCTATGCCCAGAAAAGAGGGCATGGAGAGGAAGGACCTGCTGAAGGCCAACGTGGCCATTTTTAAAACCCAAGGTGAAGCACTGGAGAAGTATGCCAAGAAGACCGTCAAGgtgCTAGTTGTCGGGAACCCAGCCAACACCAACTGCTTGATTGCCTCCAAATCCGCTCCCTCCATTCCTAAGGAGAACTTCTCCTGCCTGACCCGTCTGGACCACAACAGGGCTCGCTCTCAGGTGGCGATGCGTGTCGGTGTGCCCTCTGACAGTGTAAAGAACGTGACTATCTGGGGGAATCACTCCTCTACTCAGTACCCGGATGTGCACCATGCTATCGTGACCCGTAATGGGAAGGAGATCGCCGCTTTTGATGCTGTGAATGACGAAAGCTGGCTGAAGGGGGACTTTATCTCTACAGTGCAGCAGAGAGGTGCAGCCGTCATCAAGGCCAGAAAACTCTCAAGCGCAATGTCTGCTGCCAAAGCCATCTGTGACCACATGAGGGACATCTGGTTCGGCACTCCAGATGGTGAATGGGTGTCTATGGGGATCTACTCTTCTGGCAATTCCTATGGAGTTCCTGATGACCTCATGTACTCCTTCCCTGTAAAGATCAAGAACAAGAGCTGGAAGGTGGTTGACGGCCTCTCCATCAACGATTTCTCCCGTGGAAAGATGGACGCCACGGCTGCCGAGCTGGTGGAGGAGAGAGACACGGCGCTCACCTTCCTCTCAGCGTGACTCCAGCACTCCACAAACACACGGCAGACGCTAGACTCAAACTTCCAGAGTTCCCGACTCTAAAGTCCTGTAGATTTCACAGCTGGCCGTGATCGAGTGTGTGGGTCTTCATGTCCTGTATgcgtgagtgtatgagtgtgtgtgtgtgtgtgttactaaaCCAGAAACGTTCGCAATGTAACTTCCCTCTGCTTGGAGTGTTTGGGGCAACACCTGAAGGAGTTTATTTCCAATCTGAATCTTTACGCACAGTTGTCCTGACTAAAGAATCTTCTGTCATACAACAATAAACGACCATGTggaaaacagtt
>TCONS_00001089
AGAGCGGCGAAATCAACTACATATCCCAGTGTGCAGCATTTTCGTGTCAGTGAAAGCGTATGACATTTCCATACAAGAATAGAGGTGACCCTCCGTTCGGTCTGAGTGGCAGAGCAGCACATCTTTGGCGCACATCTCAACCTGCACAATCAGACCCGAATCATGGCCGAACCGATCCGTGTTTTGGTGACTGGCGCCGCCGGACAGATCGCCTATTCTCTGCTCTACAGCATCGCTAAAGGAGATGTGTTCGGCAAGGACCAGCCAATCATCTTGGTGCTCCTGGATATCACTCCCATGCTGCCGGTGCTGGATGGAGTCGTCATGGAGCTGCAGGATTGTGCTCTTCCTCTTCTGAGAGAGGTGATTCCCACTGATAAGGTTGAGGTGGGCTTCAAGGATCTTGATGCTGCCATCTTGGTGGGCTCTATGCCCAGAAAAGAGGGCATGGAGAGGAAGGACCTGCTGAAGGCCAACGTGGCCATTTTTAAAACCCAAGGTGAAGCACTGGAGAAGTATGCCAAGAAGACCGTCAAGgtgCTAGTTGTCGGGAACCCAGCCAACACCAACTGCTTGATTGCCTCCAAATCCGCTCCCTCCATTCCTAAGGAGAACTTCTCCTGCCTGACCCGTCTGGACCACAACAGGGCTCGCTCTCAGGTGGCGATGCGTGTCGGTGTGCCCTCTGACAGTGTAAAGAACGTGACTATCTGGGGGAATCACTCCTCTACTCAGTACCCGGATGTGCACCATGCTATCGTGACCCGTAATGGGAAGGAGATCGCCGCTTTTGATGCTGTGAATGACGAAAGCTGGCTGAAGGGGGACTTTATCTCTACAGTGCAGCAGAGAGGTGCAGCCGTCATCAAGGCCAGAAAACTCTCAAGCGCAATGTCTGCTGCCAAAGCCATCTGTGACCACATGAGGGACATCTGGTTCGGCACTCCAGATGGTGAATGGGTGTCTATGGGGATCTACTCTTCTGGCAATTCCTATGGAGTTCCTGATGACCTCATGTACTCCTTCCCTGTAAAGATCAAGAACAAGAGCTGGAAGGTGGTTGACGGCCTCTCCATCAACGATTTCTCCCGTGGAAAGATGGACGCCACGGCTGCCGAGCTGGTGGAGGAGAGAGACACGGCGCTCACCTTCCTCTCAGCGTGACTCCAGCACTCCACAAACACACGGCAGACGCTAGACTCAAACTTCCAGAGTTCCCGACTCTAAAGTCCTGTAGATTTCACAGCTGGCCGTGATCGAGTGTGTGGGTCTTCATGTCCTGTATgcgtgagtgtatgagtgtgtgtgtgtgtgtgttactaaaCCAGAAACGTTCGCAATGTAACTTCCCTCTGCTTGGAGTGTTTGGGGCAACACCTGAAGGAGTTTATTTCCAATCTGAATCTTTACGCACAGTTGTCCTGACTAAAGAATCTTCTGTCATACAACAATAAACGACCATGTggaaaaca
>TCONS_00001090
CTGAGTGGCAGAGCAGCACATCTTTGGCGCACATCTCAACCTGCACAATCAGACCCGAATCATGGCCGAACCGATCCGTGTTTTGGTGACTGGCGCCGCCGGACAGATCGCCTATTCTCTGCTCTACAGCATCGCTAAAGGAGATGTGTTCGGCAAGGACCAGGTGAGACTGTCTGAGACCCCCCCCTGTCTTATTGCATAACAGGACATTGAAGGGGGAAATAAACCCGCAAGTGGAGCAAACTGGATTTTAAATCATGCATCAGTGTTATGTAACTAAGCATGTGTGATTAAAATATGCGTCTCACTGTGATGCGAGTCTGCTCAGAATAAAAGTCGCGCAGTCACTGTTCCTGCACTATA
>TCONS_00001091
GCAGAAAGCGTCATAAATAAACGCTCAAATCTGAATTTTATGATATAATCTTTGATATAAGTACTCATTTCGGACACTAGGCCTTTGTAGTGATAAATAGGTCACGCTGTTCACGGCATTgactgtgtgtgttgtttttttgcagGCCGAACCGATCCGTGTTTTGGTGACTGGCGCCGCCGGACAGATCGCCTATTCTCTGCTCTACAGCATCGCTAAAGGAGATGTGTTCGGCAAGGACCAGCCAATCATCTTGGTGCTCCTGGATATCACTCCCATGCTGCCGGTGCTGGATGGAGTCGTCATGGAGCTGCAGGATTGTGCTCTTCCTCTTCTGAGAGAGGTGATTCCCACTGATAAGGTTGAGGTGGGCTTCAAGGATCTTGATGCTGCCATCTTGGTGGGCTCTATGCCCAGAAAAGAGGGCATGGAGAGGAAGGACCTGCTGAAGGCCAACGTGGCCATTTTTAAAACCCAAGGTGAAGCACTGGAGAAGTATGCCAAGAAGACCGTC
>TCONS_00001092
TGTGACCACATGAGGGACATCTGGTTCGGCACTCCAGATGGTGAATGGGTGTCTATGGGGATCTACTCTTCTGGCAATTCCTATGGAGTTCCTGATGACCTCATGTACTCCTTCCCTGTAAAGATCAAGGTTGGTTTTACTCGCTTTAAGGCCCTTTCACATCACAAACAATCAACATTAGCATCTGCTCTGATGCATAACATTATAAGAGCCCTGTCGCTTTAAAGCtagctggattctgattggttgccaATAGCATTATCATTCATCAACTGTAAAAACAATTCTAGAAATTAAACAATGCAATTATTTTAGCTGTTATTGTTATGGTTGAGTCCAAAAGCATTGAGTATGTGACTTGTATTACCCTATAATTCCAGTTATGcaagcatgtttgtttgtttggtatattttttaaatataatatttttttaattgctgaatccaacacaaaatcaagaaaaagtctcgcaaaattcttaatttaaacacaaaataattacaaaa

Function

symbol description
mdh1aa Predicted to enable L-malate dehydrogenase activity. Predicted to be involved in NADH metabolic process; dicarboxylic acid metabolic process; and tricarboxylic acid cycle. Predicted to act upstream of or within carbohydrate metabolic process and carboxylic acid metabolic process. Predicted to be active in cytosol. Is expressed in several structures, including digestive system; integument; mesoderm; pectoral fin; and sensory system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 88. Orthologous to human MDH1 (malate dehydrogenase 1).

GO:

id name namespace
GO:0006099 tricarboxylic acid cycle biological_process
GO:0006107 oxaloacetate metabolic process biological_process
GO:0006108 malate metabolic process biological_process
GO:0006734 NADH metabolic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0005975 carbohydrate metabolic process biological_process
GO:0019752 carboxylic acid metabolic process biological_process
GO:0005829 cytosol cellular_component
GO:0016491 oxidoreductase activity molecular_function
GO:0016615 malate dehydrogenase activity molecular_function
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor molecular_function
GO:0003824 catalytic activity molecular_function
GO:0030060 L-malate dehydrogenase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040204-1 Predicted to enable L-malate dehydrogenase activity. Predicted to be involved in NADH metabolic process; dicarboxylic acid metabolic process; and tricarboxylic acid cycle. Predicted to act upstream of or within carbohydrate metabolic process and carboxylic acid metabolic process. Predicted to be active in cytosol. Is expressed in several structures, including digestive system; integument; mesoderm; pectoral fin; and sensory system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 88. Orthologous to human MDH1 (malate dehydrogenase 1).

Ensembl:

ensembl_id ENSDARG00000017772

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001087 False 689 mRNA 0.54 4 50968908 50983855
TCONS_00001088 False 1714 mRNA 0.52 9 50968908 50990889
TCONS_00001089 False 1472 mRNA 0.52 9 50976975 50990886
TCONS_00001090 False 363 mRNA 0.49 2 50977076 50977997
TCONS_00001091 False 514 lncRNA 0.49 3 50977554 50983939
TCONS_00001092 True 507 mRNA 0.35 2 50987535 50988174

Neighbor

gene id symbol gene type direction distance location
XLOC_000640 NA coding upstream 15350 50943592 ~ 50953558 (+)
XLOC_000639 otx2a coding upstream 38951 50921266 ~ 50929957 (+)
XLOC_000638 BX855617.1 coding upstream 114430 50854364 ~ 50854478 (+)
XLOC_000637 NA coding upstream 160460 50733156 ~ 50808448 (+)
XLOC_000636 herc3 coding upstream 277370 50639416 ~ 50691538 (+)
XLOC_000642 ugp2a coding downstream 6267 50997156 ~ 51015627 (+)
XLOC_000643 NA coding downstream 24969 51015858 ~ 51018551 (+)
XLOC_000644 dpy30 coding downstream 48669 51039558 ~ 51042332 (+)
XLOC_000645 srd5a2a coding downstream 75782 51066671 ~ 51073128 (+)
XLOC_000646 btbd3a coding downstream 200160 51191049 ~ 51197601 (+)
XLOC_000633 NA non-coding upstream 437214 50528134 ~ 50531694 (+)
XLOC_000632 NA non-coding upstream 576119 50389319 ~ 50392789 (+)
XLOC_000651 BX547996.1 non-coding downstream 474579 51465468 ~ 51465582 (+)
XLOC_000655 CU464066.1 non-coding downstream 692630 51683519 ~ 51683618 (+)
XLOC_000656 NA non-coding downstream 703862 51694751 ~ 51717215 (+)
XLOC_000658 NA non-coding downstream 762089 51752978 ~ 51826020 (+)

Expression


Co-expression Network