XLOC_006477 (abcg8)


Basic Information

Item Value
gene id XLOC_006477
gene name abcg8
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 10926528 ~ 10945394 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012561
AAACGCCGACCCTTATCAGTGGACCTTTGCTCCATTTGCTATAAAGAGTCGCTTTCTCCTCTACTTCTCTTCAGTTTTTGCAGGGAAACAAGAGGAGCGGGTACTTCTATAAGTTGGGTACTTGGCAAGAGGGGGAACAGACCCCTTTGTACCGCGTCCGCCATGTCAGACGATACAGTTTTCCACTCAGGAGAAAGTTTCAGCTCTTCTTATGAAAAACAGATAAAGGGTCGAGATATTCTTTTTTCATCTCCAGAGGAGGACAGCAGTCTGTATTTTACTTACAGCGGAGGCCGCAATGAACTGGAAGTCCGCAATCTCAACTATGAGGTGGACACAGCAGCACAAATACCCTGGTATGAGAAGCTGTCAGAGTTTAAGATGCCCTGGGAGATGCACAGCAATAAGCAGACGGTCATAAAGGATCTGAACCTGCATGTTCACAGTGGACAGATGCTTGCTGTCATTGGCAGCTCAGGCTGTGGGAAGACCTCCTTACTGGACATTATAACATGTCGAGATGAGGGTGGCTCCATGAATTCAGGAGAGATCCTGATCAACGGGAAACCTTCCACGCGATCTCTGGTGAAGAAAAGCATAGCTCATGTACGGCAGGATGACCGTTTGTTACCACATCTCACAGTACGAGAGACGCTAGCTTTTGTGGCAAAACTGCGTCTGCCTGCGAACTTCAGCCAAAAACAGAGAGATCAAAGGGTGGATGATGTGATTGCGGAGCTGCGTCTGAGGCAGTGCGCTCACACACGTGTGGGCAATGAGTATGTGAGAGGAGTGTCAGGTGGGGAGAGGAGGAGAGTCAGCATCGCTGTACAGCTCCTCTGGAATCCAGgTATACTCATTCTAGATGAGCCTACTTCAGGTCTGGACAGTTTCACGGCTCATAATTTGGTCATCACATTATATCGTCTGGCTCGAGGGAACCGGCTAGTGTTGCTGTCAGTGCATCAGCCTCGCTCAGATATCTTTCAGCTCTTTGACCTTGTGGTGCTGCTGTCCTCTGGTTCAGCCGTGTACTGTGGTCAGGCCAAAGACATGGTGTCTTACTTCACCACTCTCGGGTACCCGTGTCCACGCTATTGCAACCCGTCCGACTACTACGTGGACTTGATAAGCATTGATCGGCGCACTCCTGAAAAAGAAGCACAGTGTTTGGAGAAAGCCAGCATGTTGGCGGCCCAGTTTTTAGAGAAGGTGAAGAACAATGAAGATTTCATGTGGAAATCGGAAGTCTGTGGTCCTCCGGCACTGGAAGCCCCTCAAAGTGTTCCTTCTGTCTCAATGAAAGAATCAGTGATCACAGTTTCCAAACAGAAGGATCAGCTGCCGGGAAAAGTGCATCAGTTCACAACCTTAATCAGACGGCAGGTATTTAATGACTACCGGGACCTGGTGACACTGGTGGTTCATGGTTTAGAAGCTTTGCTGATGTCATTGCTCATCGGTTTCCTATATTTCGGGTGCACAGAGGAAGGTCTTTCCATCCAAGATACAGTGGCTTTGCTCTACATGATAGGAGCTCTGACACCCTTTGCTGTGGTGCTGGACGTCATCgcgaagtGTCATTCAGAGAGAGCCATGCTGTATCATGAACTGGAAGATGGCATGTACTCGGTCACCCCATACTTTTTTGCCAAGGTACTTGGAGAGCTGCCAGAGCACTGTGCCTTTACACTGGTATACGGTGTGCCCATCTACTGGTTGGCCGGGCTCAACGTCGCTCCTGATCGCTTTCTGCTCAACTTCCTGTTGGTTTGGCTGACGGTGTATTGTAGCCGCTCCATGGCACTGTTTGTGGCAGCAGCCCTGCCAACGCTGCAGACCTCATCTTTCATGGGCAATGCTCTTTTCACAGTATTCTACCTTACCGCTGGCTTTGTCATCAGTCTGGAAAACATGTGGATGGTGGCGTCTTGGTTTTCCTACATATCCTTCATGCGCTGGGGTTTTGAGGGGATGCTGCAGGTTCAGTTTCGTGGGACCAGAATCCCAATCACTATTGGAAACCTCACTGTAGAATTCGATGGTATTAAGgttgtggagatgatgaagatgaaccaGTATCCGCTGTTCTCCTGCTACCTGGTGCTTATTGCTGTTTCTTTGGTTTTCATATTGCTCTATTATCTGTCCCTCaaattcattaaacagaaatccaGTCAGGACTGGTGAGGGAGCGATATATTCTGGTCCATATTGGAGCTTGTTTTTGCCAAGCAGCTGTAAAGTTCCCAACTATAGATCTTGGAAAACAAATCTGTTTGTTTAGGCTAGTTTGCAACAAGAACCATATATCTGTTTCCAGTTTATTCAGTGCACTGATGCATATTCAGTTTATTCCTTCTCTTGTTTTCACTTGATTTAGTAGTTTGAAAGCTTACTAAAAACAGTGATCAAATCGTGAGCTTTGTTGTACTTCCACTCTCTGCCGCTGGATGGCAGAAGTGTACTATGTTTTTTcaatctttaaagggatagttcacccaaaaataggaCTTTCCTTATCATTTAAACACATAAGGTAtggatttctttcttctgttgaacacgaaacaatataagaaactcaaacaggtttgaaacaaatgaaagatgagtaaatgatgacaggatttttatttttgggtcaactatccctataatagttgtaaataatagttgtttttgtttgttttattttattttttgttaaatcacTTGAGATCATGCTTGCTAGatacatttaataacatttattgcaTCTCTTtagtgtaattttatttaatttcattttttactCCTGT
>TCONS_00012562
GCTCCATTTGCTATAAAGAGTCGCTTTCTCCTCTACTTCTCTTCAGTTTTTGCAGGGAAACAAGAGGAGCGGGTACTTCTATAAGTTGGGTACTTGGCAAGAGGGGGAACAGACCCCTTTGTACCGCGTCCGCCATGTCAGACGATACAGTTTTCCACTCAGGAGAAAGTTTCAGCTCTTCTTATGAAAAACAGATAAAGGGTCGAGATATTCTTTTTTCATCTCCAGAGGAGGACAGCAGTCTGTATTTTACTTACAGCGGAGGCCGCAATGAACTGGAAGTCCGCAATCTCAACTATGAGGTGGACACAGCAGCACAAATACCCTGGTATGAGAAGCTGTCAGAGTTTAAGATGCCCTGGGAGATGCACAGCAATAAGCAGACGGTCATAAAGGATCTGAACCTGCATGTTCACAGTGGACAGATGCTTGCTGTCATTGGCAGCTCAGGCTGTGGGAAGACCTCCTTACTGGACATTATAACATGTCGAGATGAGGGTGGCTCCATGAATTCAGGAGAGATCCTGATCAACGGGAAACCTTCCACGCGATCTCTGGTGAAGAAAAGCATAGCTCATGTACGGCAGGATGACCGTTTGTTACCACATCTCACAGTACGAGAGACGCTAGCTTTTGTGGCAAAACTGCGTCTGCCTGCGAACTTCAGCCAAAAACAGAGAGATCAAAGGGTGGATGATGTGATTGCGGAGCTGCGTCTGAGGCAGTGCGCTCACACACGTGTGGGCAATGAGTATGTGAGAGGAGTGTCAGGTGGGGAGAGGAGGAGAGTCAGCATCGCTGTACAGCTCCTCTGGAATCCAGgTATACTCATTCTAGATGAGCCTACTTCAGGTCTGGACAGTTTCACGGCTCATAATTTGGTCATCACATTATATCGTCTGGCTCGAGGGAACCGGCTAGTGTTGCTGTCAGTGCATCAGCCTCGCTCAGATATCTTTCAGCTCTTTGACCTTGTGGTGCTGCTGTCCTCTGGTTCAGCCGTGTACTGTGGTCAGGCCAAAGACATGGTGTCTTACTTCACCACTCTCGGGTACCCGTGTCCACGCTATTGCAACCCGTCCGACTACTACGTGGACTTGATAAGCATTGATCGGCGCACTCCTGAAAAAGAAGCACAGTGTTTGGAGAAAGCCAGCATGTTGGCGGCCCAGTTTTTAGAGAAGGTGAAGAACAATGAAGATTTCATGTGGAAATCGGAAGTCTGTGGTCCTCCGGCACTGGAAGCCCCTCAAAGCAGTGTTCCTTCTGTCTCAATGAAAGAATCAGTGATCACAGTTTCCAAACAGAAGGATCAGCTGCCGGGAAAAGTGCATCAGTTCACAACCTTAATCAGACGGCAGGTATTTAATGACTACCGGGACCTGGTGACACTGGTGGTTCATGGTTTAGAAGCTTTGCTGATGTCATTGCTCATCGGTTTCCTATATTTCGGGTGCACAGAGGAAGGTCTTTCCATCCAAGATACAGTGGCTTTGCTCTACATGATAGGAGCTCTGACACCCTTTGCTGTGGTGCTGGACGTCATCgcgaagtGTCATTCAGAGAGAGCCATGCTGTATCATGAACTGGAAGATGGCATGTACTCGGTCACCCCATACTTTTTTGCCAAGGTACTTGGAGAGCTGCCAGAGCACTGTGCCTTTACACTGGTATACGGTGTGCCCATCTACTGGTTGGCCGGGCTCAACGTCGCTCCTGATCGCTTTCTGCTCAACTTCCTGTTGGTTTGGCTGACGGTGTATTGTAGCCGCTCCATGGCACTGTTTGTGGCAGCAGCCCTGCCAACGCTGCAGACCTCATCTTTCATGGGCAATGCTCTTTTCACAGTATTCTACCTTACCGCTGGCTTTGTCATCAGTCTGGAAAACATGTGGATGGTGGCGTCTTGGTTTTCCTACATATCCTTCATGCGCTGGGGTTTTGAGGGGATGCTGCAGGTTCAGTTTCGTGGGACCAGAATCCCAATCACTATTGGAAACCTCACTGTAGAATTCGATGGTATTAAGgttgtggagatgatgaagatgaaccaGTATCCGCTGTTCTCCTGCTACCTGGTGCTTATTGCTGTTTCTTTGGTTTTCATATTGCTCTATTATCTGTCCCTCaaattcattaaacagaaatccaGTCAGGACTGGTGAGGGAGCGATATATTCTGGTCCATATTGGAGCTTGTTTTTGCCAAGCAGCTGTAAAGTTCCCAACTATAGATCTTGGAAAACAAATCTGTTTGTTTAGGCTAGTTTGCAACAAGAACCATATATCTGTTTCCAGTTTATTCAGTGCACTGATGCATATTCAGTTTATTCCTTCTCTTGTTTTCACTTGATTTAGTAGTTTGAAAGCTTACTAAAAACAGTGATCAAATCGTGAGCTTTGTTGTACTTCCACTCTCTGCCGCTGGATGGCAGAAGTGTACTATGTTTTTTcaatctttaaagggatagttcac
>TCONS_00012563
CTATAAGTTGGGTACTTGGCAAGAGGGGGAACAGACCCCTTTGTACCGCGTCCGCCATGTCAGACGATACAGTTTTCCACTCAGGAGAAAGTTTCAGCTCTTCTTATGAAAAACAGATAAAGGGTCGAGATATTCTTTTTTCATCTCCAGAGGAGGACAGCAGTCTGTATTTTACTTACAGCGGAGGCCGCAATGAACTGGAAGTCCGCAATCTCAACTATGAGGTGGACACAGCAGCACAAATACCCTGGTATGAGAAGCTGTCAGAGTTTAAGATGCCCTGGGAGATGCACAGCAATAAGCAGACGGTCATAAAGGATCTGAACCTGCATGTTCACAGTGGACAGATGCTTGCTGTCATTGGCAGCTCAGGCTGTGGGAAGACCTCCTTACTGGACATTATAACATGTCGAGATGAGGGTGGCTCCATGAATTCAGGAGAGATCCTGATCAACGGGAAACCTTCCACGCGATCTCTGGTGAAGAAAAGCATAGCTCATGTACGGCAGGATGACCGTTTGTTACCACATCTCACAGTACGAGAGACGCTAGCTTTTGTGGCAAAACTGCGTCTGCCTGCGAACTTCAGCCAAAAACAGAGAGATCAAAGGGTGGATGATGTGATTGCGGAGCTGCGTCTGAGGCAGTGCGCTCACACACGTGTGGGCAATGAGTATGTGAGAGGAGTGTCAGGTGGGGAGAGGAGGAGAGTCAGCATCGCTGTACAGCTCCTCTGGAATCCAGgTATACTCATTCTAGATGAGCCTACTTCAGGTCTGGACAGTTTCACGGCTCATAATTTGGTCATCACATTATATCGTCTGGCTCGAGGGAACCGGCTAGTGTTGCTGTCAGTGCATCAGCCTCGCTCAGATATCTTTCAGCTCTTTGACCTTGTGGTGCTGCTGTCCTCTGGTTCAGCCGTGTACTGTGGTCAGGCCAAAGACATGGTGTCTTACTTCACCACTCTCGGGTACCCGTGTCCACGCTATTGCAACCCGTCCGACTACTACGGTGAGTGGGACTCTAAAGTGATGACTGATCACTTTAGCTGATCCTGCTGTTTGGTTATTGTTTCTTAACTGTGAACTTCTAATGCAGTGGACTTGATAAGCATTGATCGGCGCACTCCTGAAAAAGAAGCACAGTGTTTGGAGAAAGCCAGCATGTTGGCGGCCCAGTTTTTAGAGAAGGTGAAGAACAATGAAGATTTCATGTGGAAATCGGAAGTCTGTGGTCCTCCGGCACTGGAAGCCCCTCAAAGGTAGCCTATAGAGTTTCAAATTTATATTGTTGTTACatcatgaagtttttttttttcctttgtttttttcatttctcCACGAAATGCGTGAACTGTCATAATAAATTTTCTGTGAAGTCTTA

Function

symbol description
abcg8 Predicted to enable ATP binding activity and ATPase-coupled transmembrane transporter activity. Predicted to be involved in cholesterol homeostasis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in arteriosclerosis; familial hyperlipidemia; gallbladder disease; obesity; and sitosterolemia. Orthologous to human ABCG8 (ATP binding cassette subfamily G member 8).

GO:

id name namespace
GO:0042632 cholesterol homeostasis biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016887 ATPase activity molecular_function

KEGG:

id description
ko02010 ABC transporters
ko04976 Bile secretion
ko04975 Fat digestion and absorption
ko04979 Cholesterol metabolism
ko02000 Transporters

ZFIN:

id description
ZDB-GENE-050517-41 Predicted to enable ATP binding activity and ATPase-coupled transmembrane transporter activity. Predicted to be involved in cholesterol homeostasis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in arteriosclerosis; familial hyperlipidemia; gallbladder disease; obesity; and sitosterolemia. Orthologous to human ABCG8 (ATP binding cassette subfamily G member 8).

Ensembl:

ensembl_id ENSDARG00000063059

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012561 False 2801 mRNA 0.45 13 10926528 10945394
TCONS_00012562 False 2476 mRNA 0.47 13 10926828 10945366
TCONS_00012563 True 1386 mRNA 0.47 6 10936430 10945288

Neighbor

gene id symbol gene type direction distance location
XLOC_006476 AL928999.1 coding downstream 13926 10912486 ~ 10912602 (-)
XLOC_006475 ppm1ba coding downstream 195203 10682427 ~ 10731325 (-)
XLOC_006474 slc3a1 coding downstream 253990 10649069 ~ 10672538 (-)
XLOC_006473 camkmt coding downstream 305734 10360444 ~ 10620794 (-)
XLOC_006472 NA coding downstream 579638 10275286 ~ 10346890 (-)
XLOC_006478 cep170aa coding upstream 35361 10980755 ~ 11072964 (-)
XLOC_006479 akt3a coding upstream 229814 11175208 ~ 11378392 (-)
XLOC_006480 NA coding upstream 497444 11442838 ~ 11445780 (-)
XLOC_006481 adss2 coding upstream 544559 11489953 ~ 11536951 (-)
XLOC_006482 CR556710.1 coding upstream 620342 11565736 ~ 11565863 (-)
XLOC_006471 BX537274.2 misc downstream 661623 10264741 ~ 10264905 (-)
XLOC_006338 rn7sk misc downstream 10100303 825904 ~ 826225 (-)
XLOC_006469 NA non-coding downstream 673494 10250174 ~ 10253034 (-)
XLOC_006468 NA non-coding downstream 694450 10150919 ~ 10232078 (-)
XLOC_006467 NA non-coding downstream 807593 10077215 ~ 10118935 (-)
XLOC_006492 CR792443.2 non-coding upstream 1029058 11974452 ~ 11974568 (-)
XLOC_006496 CR792443.1 non-coding upstream 1160384 12105778 ~ 12105894 (-)
XLOC_006497 NA non-coding upstream 1171719 12117113 ~ 12118250 (-)

Expression


Co-expression Network