XLOC_006501 (enpep)


Basic Information

Item Value
gene id XLOC_006501
gene name enpep
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 12543634 ~ 12581388 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012604
ATGGAAAGCCTGGACTTCGAGAAGAAGGAAAAGCGGTACTGTATCCGAGGAAAGCACGCTGCTATCATCTGTGCCGTCATCGTAGTGACAGGTGTAGCTGTGGGACTTGGAGTTGGCTTAAGCTTGAATTCTTCATCCGAAAAGGAAACACCATTACCAACTCCATTACCCACAGAAGTGCCTGATGATCGCCCATGCAAACCATCTGAGAACACCAATGGCGGCTGGAGCAATTTCCGATTACCTGACTACATTCTTCCGTTCCATTACGATCTGCATATGGAGCCTGACCTCAACACGGACATCTACACTGGGGACGTGTCTGTACATCTGAAACTGACTCAGCCCAGTCAGCACCTGTGGCTCCACATCCGGGACACTTTTGTCACTGTGATGCCTTCACTACAGCGCAGCAGCCCGTCTGGTGTGACCTCTGTCAAGTTGAAGCAATGCTTTGAATACAAGCCGCAGGAGTACGTGGTTGTGGAAGCGGCTGAGCAGTTGAGCGTTACAGGGCCGGATGAACACTACGTCCTCACTCTGCACTTCCAGGGCTGGTTAAATGGCTCTCTGGTTGGCTTCTACAGGACCACGTATCAGGAGAATGGAGTTACCAAGAAAATCGCTGCAACAGACCATGAACCCACGGACGCTCGTAAATCTTTTCCATGTTTTGATGAGCCCAACAAAAAGGCCACCTACACAATCTCCATCACCCATGACAGTACATATAAAGCACTGTCCAACATGCCTGTGGAGAAAACAGAAAAACTTTCAGAACAAAAGACTAAAACATCCTTCATGAAGTCAGTAAAGATGAGCACTTATCTGGTGTGTTTTGCGGTGCATCAGTTCGATTTTGTGGAGCGGACCTCGAAAAGAGGAATACCGctgCGGATCTATGCTCAGCCTTTGCAGATCTCCACGGCTGCATATGCTGCAGATGTCACACAGGTCATATTCGATTACTTTGAGGAATATTTCGACATGGAATATTCAATACAAAAACTTGATAAGATAGCGATCCCAGACTTTGGGACAGGAGCGATGGAGAACTGGGGCTTGATCACTTACAGAGAAACCAACCTGCTGTTCGATGAGAAGGAGTCATCCTCGGTCAACAAGCAGCGAGTGGCCAGTGTCATTGCACACGAGCTTGTCCATCAGTGGTTTGGAAATATTGTGACTATGGACTGGTGGGATGACCTGTGGCTGAACGAGGGCTTTGCCAGCTTTTTTGAGTATATTGGAGTGGAAGAAGCTGAGCATGACTGGGGAATGCGTGACGTCATGCTTATCAACGATGTATATCCTGTCATGGTCGATGATGCCCTTCTCTCCTCGCATCCCATTATTGTGGATGTGTCGAGCCCAGCTGAGATCACATCTGTGTTTGATGCCATCTCATATAACAAGGGAGCTTCTATTTTGCGAATGCTGGAGGACTTACTTGGCCGAGAGACATTTAGGGATGGTTGTCGAAGATATCTGAAGACCTACCTCTTCCAGAACGCAAAGACTTCAGACTTCTGGAAAGCCTTGGCTGATGAGAGTGGCTTACCCGTGGCAGACATTATGGACACATGGACCAAGCAGATGGGTTATCCAGTGCTCAGTCTGACCAACACAGACACTGAAGCTAAACTCACGCAGACCAGGTTTCTTCTGGACCCTAATGCTGACCCTAGTCAGCCCACCACTCCACTGGGGTATAAATGGACTATTCCAGTGAAATGGAAAGCACTTGACTCCACAAACAACTCttttatatttgaaaaaggaCAAACAGAGGCAGTCATTAGTGGATACTCGCATGCTACCAATGGTCTTATCAAAGTCAACAAAGACCACATGGGCTTCTACAGAGTAAATCATCATGACCAAATGTGGAGCGATATTGCTGAACAACTTCTTATGGATCATCAGGTCTACGATGCAACTGACAGAAGCAGCTACATTGATGATATATTCGCATTAGGACGGGCAGATATGGTTGATTACGGGAATGCCTTCAATTTAACAAGATATCTGGCTGACGAAACCGAATATATTGTGTGGGATCGAGTTTCTGCTTCTATCTCCTACGTGAGAGAAATGTTGGCTGATGATACAGTGCTGTACCCCTTATTTCAGAAATTATTCAGGGGTCACGTGCAGAAGATATCCAGAGAGCTTGGCTGGAAGGATGAGGGGAATCAAACACAGCGGCTGCTGAGAGAGATCGTTTTGGGCATTGCATGTCAAATGGGTGACCAGGAAGCTCTTGACCAAGCCTCTGATATTTTCAATAAATGGATTAAAGGAACAATCGGCAGTGTGCCTGTGAACTTGCGTCTGCTGGTATATCGGTACGGCATGATGAACTCAGGAACAGAGGAGAGCTGGGAAATCATGTTCCAGAAGTATCTGTCTGCCACTCTGGCCCAGGAGAAAGATAAGCTGCTCTATGGTCTGGCTTCAGTCAAAAATATTCATCTGCTTCATAGGTTGCTTGAAGCCACAAAAAATGAAAGCATCATAAGGAGTCAAGATGTTTTTACTTTAGTGCAATACGTGTCACGAAGCTCTGATGGTAAAATTATGGCCTGGGACTGGATGACGCTCAACTGGGATTACCTGGTGAACAGATACACTATCAATGACAGAAATTTGGGCCGCCTGCCAGCCAGAATTACAACTACATACAGCTCTAATCTTCAACTGTGGAAGATGGAGCACTTTTTTGCCCTGCACCCGAATGCAGGAGCAGGTGAGATGCCCAGAAAGCAGGCACTGGAGACTGTGAAGAACAATATCGAATGGGTGGAAAGGAATAAGGATGAGATCCGGTTCTGGCTGGAGAACAATGTGTCCTAGTACTAGAAGAACATTTTTTGCCCACCCCTCAAGTAATTAGGATTCACAAGTCAATGAATTGCTCAGGGCAGCTTGAAAATGAATCTTTAGCAAAGAGCCATAATTGCGTTCATGACAGTTAAATGAAACAAAACGCTTTCTGGAACTACAGTAGGCATTACAAATCCTTTGGAACTGTacattgtttctttatttaatgtgttgcaattgacataaaatgttttatttgtaaaa

Function

symbol description
enpep Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including peptide catabolic process; proteolysis; and regulation of blood pressure. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in endoderm; gut; intestinal bulb; pronephric duct; and pronephros. Orthologous to human ENPEP (glutamyl aminopeptidase).

GO:

id name namespace
GO:0008217 regulation of blood pressure biological_process
GO:0006508 proteolysis biological_process
GO:0043171 peptide catabolic process biological_process
GO:0007165 signal transduction biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004177 aminopeptidase activity molecular_function
GO:0070006 metalloaminopeptidase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008237 metallopeptidase activity molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0042277 peptide binding molecular_function

KEGG:

id description
ko04614 Renin-angiotensin system
ko01002 Peptidases and inhibitors
ko04147 Exosome
ko04090 CD molecules

ZFIN:

id description
ZDB-GENE-050309-218 Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including peptide catabolic process; proteolysis; and regulation of blood pressure. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in endoderm; gut; intestinal bulb; pronephric duct; and pronephros. Orthologous to human ENPEP (glutamyl aminopeptidase).

Ensembl:

ensembl_id ENSDARG00000057064

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012604 True 3090 mRNA 0.46 20 12543634 12581388

Neighbor

gene id symbol gene type direction distance location
XLOC_006500 si:dkey-20i10.7 coding downstream 49059 12488863 ~ 12494575 (-)
XLOC_006499 lamtor3 coding downstream 57558 12479264 ~ 12486076 (-)
XLOC_006498 commd8 coding downstream 153886 12378074 ~ 12389748 (-)
XLOC_006497 NA coding downstream 425384 12117113 ~ 12118250 (-)
XLOC_006496 CR792443.1 coding downstream 437740 12105778 ~ 12105894 (-)
XLOC_006502 NA coding upstream 5609 12586997 ~ 12587412 (-)
XLOC_006503 lrit3b coding upstream 10120 12591508 ~ 12602920 (-)
XLOC_006504 adh8b coding upstream 51835 12633223 ~ 12646752 (-)
XLOC_006505 adh8a coding upstream 72587 12653975 ~ 12660318 (-)
XLOC_006506 fam241a coding upstream 83478 12664866 ~ 12667220 (-)
XLOC_006471 BX537274.2 misc downstream 2278729 10264741 ~ 10264905 (-)
XLOC_006338 rn7sk misc downstream 11717409 825904 ~ 826225 (-)
XLOC_006492 CR792443.2 non-coding downstream 569066 11974452 ~ 11974568 (-)
XLOC_006482 CR556710.1 non-coding downstream 977771 11565736 ~ 11565863 (-)
XLOC_006480 NA non-coding downstream 1097854 11442838 ~ 11445780 (-)
XLOC_006507 NA non-coding upstream 167264 12748652 ~ 12756661 (-)
XLOC_006510 NA non-coding upstream 1005908 13587296 ~ 13590570 (-)
XLOC_006511 CR788322.1 non-coding upstream 1063057 13644445 ~ 13644562 (-)
XLOC_006513 CR788322.4 non-coding upstream 1089052 13670440 ~ 13670537 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G680736 NA unknown CI01180000 null 3765691 ~ 3784441 (+)
rainbow trout (Oncorhynchus mykiss) G1988943 NA non-coding NC_048590.1 CM023244.2 845438 ~ 849419 (-)