XLOC_006521 (cdc25b)


Basic Information

Item Value
gene id XLOC_006521
gene name cdc25b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 14915344 ~ 14929236 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012628
ATCAGATGTAACGACGCTGCTCATTGGCTACTTACATTGCCGCTTGCGGACTGCATGTTTTGAACATAAATAAGAGCTACATTCAGCACTTCCTCAGCAGAGTTTGGATAAGGTCAGAGAGAGTGCGATTGAATCGGCAGCTCTCTGACAACAAAGAAGATGGATTTTTAACCCCCTgactctttatttttgtttagatttgtGTAATCGGCCGTCGTTATTATGCAGATTCTCCAAGTTGTAGCTAAACTAAACCCTAAAAAGCTTTAGCCCCGATCGGGTCGCTGTGCGATTACTAGCTCGGTTTAACCCCTTGTGTTCTTAATCGCGCCTGGctgattattattttaacaacCATCTGACGATCCACGATCTTCTTCAAAAATGGATATTGATATGGTTCCAGGCGACGTTAGCCCTGTTTATGATCCATTCAGCACTGGGCCCGAATCAGCCCTCGGAGCTCCCCGCTTCACTCTGCCGGAGCTCGGTGCTCGGGGCTCCCCCTGCATGAAGAGCCTGGCCTCTCCCGGGCCCATGGCGGTGCTGTCTCCTGTCACCAACCTGGCCCTCAACATGAATAATCTCGCTGTTCTTGGAGGTCAATGTGAAACTCCAAAGCGGAAGAAAAATTTGCCCCTCCTGAAGATTCCTTCCTTCGCCTCTGATGCCTCTTCTGATGCAGGTCTTGGACTAGAGTGTCCCAGTCCTTTAGATTCTCTGGATGCTGAGCAGAAGTTTGAGAAGGCCATGCAGGACGCCACACGAGCCGTTAATGAAAAAATGCCCATCCGCAGGATACACTCTTTGCCACTCCAATTTTTGGGTCACAGTCCAAATCTGAGGAGTAAAGAATTGGATCCCTCCCGTTATGGAGTGTGGACTCATTCACATGACagtgccaataaagaaaacatggCTGAGGAGAACTTTGAGTTCAAAAAGCCCTCCATGCCTGCACTGCGCTGTCGCACTCGCTCCACCGGAGGCTCCAAGGATGCTTTTGCCTGCCGACCGAACTCTGCTCCTGCTTTAATGCTCTCCCCACCACCCACCAATCAGCCAGACTCTCCAAATGAAATCAGTCCCTTCATTCTGCGCCGTCCGTCGCTCTCCTGCCTTcaagatgatgatgacgatgatggcTTTCTGGAGGGGCTTGATGATGTGGAGaatgaCTCTGAGGTTCCTCTGGGAATGGACAGTCTTCTAACTGCTCCTCTGGTGGCCAAGCAAATTCCTGAAACTGATTCGCCTGTCATTCGCTGTCGTCCACGTGGGTTGTTCAGATCTCCATCTATGCCCTGTGCAGTCGGGCGCATCCCGCTCAAAAGACCTGAAAGACCACAAGATGAGAACACGCCTGTCCGAGTGAAGAGGAGACGGAGTCTGGCAGGGACACAAGTGTCAACCACAGAGCAGGAGGATGTTGTACATcagGTTCAGAGGTCCAAGTCCTTTAATCACTCACAGATTGAAAGAATGTTGGACACCGATCCTAGTAATGTGATTGGAGATTTTACCAAGGCTCCTGCACTGCCCACAGTACAAGGAAAACACCAAGAGTTGAAGTACATCACTCCAGAGATTATGGTTAAAGCAATGAGTGGACAGTTTCAAGATCTAGTGGAGAGGCTGTTTGTTATCGACTGCCGTTATCCGTATGAGTATGAAGGCGGCCATATTAAAGGTGCTCTTAATCTCCACCAAGAGGATCAAATCGAAGACTACTTTTTACGCAGTCCTATTCTCCCTGACTGCCCCAAGAAGCGCGTCCTGCTGATTTTTCACTGTGAATTTTCTTCAGAGCGTGGTCCACGGATGTGTCGCTACGTTAGAGAAAGAGATCGATTTGTGAATGAATACCCCAACCTCCATTACCCCGAACTCTATATCCTGAAAGGAGGCTACAAAGAATTTTTCCAGATTCACAAAGCAATATGTGAGCCCCAGATGTATAGACCGATGCTTCATGAAGAGTTTAAAGAAGACCTGAGAAAGTTTCGTCTGAAGAGCCGCACCTGGGCCGGAGAACGCAGCAAGAGAGACATGTACAGCCGTCTCAAAAAACTCTGAGGCTCGCCAAAGTGCTCATGATTTTACGGTCTTTTTGCTCATGCTGCCTTCATAACATGAGCCATGGCAGAGACCTGAagacatacatgtgtgtgttcaGTGCGGGAACCTTTCTGCGTTTCAGGGTTTGACATTAAAAGAGGACGAGAGGTTATTTTGAGTCTCtggctgtttgttttgatgtCATCACTTTTAAACTGCcactttcttttatatatattttttttaaataataataactattgaTCTCCCTTTACAAGTACACTGCGGCAAAGACACTGTCATGAACTGTTTTAAACGAACTAGAATTTGTAttctcaggtttttttatttttttatttttttttattttttattattattatttttttatccactTGCCTGTGTTAACTTGTCAGAATATTCACTATTTCCCCCCCTTCTCACCTTGagcacttttttaaataaatggatgTGGTGAataagtgctatataaatgttaaatctagttttttttttttttttttttttatataaatagctCCTTTTCCCCACATCCGATCGGTTGCTGAATGTAACTAATCTGAGAAGGATAATActataatacaattatttaaattgattttcaTATTCTAAAACCACATTATGTACCTGCTATTATTGCAAtaatgattaaattttttttctttacctcTATAATATGTAAACTCTGCCCATATTGTTCAATGTTGTTTTGAGGGAGccagcaatatattttttattttatatatatatttttttttccccccctcACTTGACTGACAGCTTTAACTCAGGGACTGGATCCTGACTTTTGCTGCAGGTTGGCAAGTGTTGACCACATCATAGTTCACCAAACCAGATCCAGTTCTGCTTGTTCTATAAACCAGTGACTGTTGAGCGTTACAAAATTCTCATTTGCCTTGCAAGGGTGTATGTGTTTTGTAAATTCTACCTTTCTGAGTGTGTTTTATTGGTCTTATGAGACTGGTTTATGTATTCATGAATAAACGTGGAGTTTGGGGTAATAa
>TCONS_00012629
GCTTGAGAGGGGGTTTGCGTTGTGTGGGCATATGGTAAATTAGAAAATGCCCCCCTTTTTCCTTCCCCGGGGCTGTTTTACATACAGGTTTGAGAAGGCCATGCAGGACGCCACACGAGCCGTTAATGAAAAAATGCCCATCCGCAGGATACACTCTTTGCCACTCCAATTTTTGGGTCACAGTCCAAATCTGAGGAGTAAAGAATTGGATCCCTCCCGTTATGGAGTGTGGACTCATTCACATGACagtgccaataaagaaaacatggCTGAGGAGAACTTTGAGTTCAAAAAGCCCTCCATGCCTGCACTGCGCTGTCGCACTCGCTCCACCGGAGGCTCCAAGGATGCTTTTGCCTGCCGACCGAACTCTGCTCCTGCTTTAATGCTCTCCCCACCACCCACCAATCAG

Function

symbol description
cdc25b Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within positive regulation of mitotic cell cycle; regulation of G2/M transition of mitotic cell cycle; and regulation of mitotic cell cycle, embryonic. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including DEL; anterior neural keel; axis; nervous system; and optic vesicle. Human ortholog(s) of this gene implicated in autosomal recessive polycystic kidney disease; cervical cancer; endometrial cancer; prostate cancer; and urinary bladder cancer. Orthologous to several human genes including CDC25B (cell division cycle 25B).

GO:

id name namespace
GO:0009794 regulation of mitotic cell cycle, embryonic biological_process
GO:0010389 regulation of G2/M transition of mitotic cell cycle biological_process
GO:0000086 G2/M transition of mitotic cell cycle biological_process
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle biological_process
GO:0006470 protein dephosphorylation biological_process
GO:1902751 positive regulation of cell cycle G2/M phase transition biological_process
GO:0110032 positive regulation of G2/MI transition of meiotic cell cycle biological_process
GO:0045931 positive regulation of mitotic cell cycle biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004725 protein tyrosine phosphatase activity molecular_function

KEGG:

id description
ko04010 MAPK signaling pathway
ko04110 Cell cycle
ko04914 Progesterone-mediated oocyte maturation
ko05206 MicroRNAs in cancer
ko01009 Protein phosphatases and associated proteins
ko03036 Chromosome and associated proteins
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-000330-5 Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within positive regulation of mitotic cell cycle; regulation of G2/M transition of mitotic cell cycle; and regulation of mitotic cell cycle, embryonic. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including DEL; anterior neural keel; axis; nervous system; and optic vesicle. Human ortholog(s) of this gene implicated in autosomal recessive polycystic kidney disease; cervical cancer; endometrial cancer; prostate cancer; and urinary bladder cancer. Orthologous to several human genes including CDC25B (cell division cycle 25B).

Ensembl:

ensembl_id ENSDARG00000010792

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012628 False 3104 mRNA 0.43 15 14915344 14929236
TCONS_00012629 True 412 mRNA 0.51 6 14922716 14926318

Neighbor

gene id symbol gene type direction distance location
XLOC_006520 ap5s1 coding downstream 6345 14902318 ~ 14908999 (-)
XLOC_006519 NA coding downstream 382090 14532720 ~ 14533254 (-)
XLOC_006517 gfra4a coding downstream 427820 14191293 ~ 14487524 (-)
XLOC_006518 AL928929.1 coding downstream 530806 14384421 ~ 14384538 (-)
XLOC_006516 NA coding downstream 900164 14013185 ~ 14015180 (-)
XLOC_006522 NA coding upstream 21559 14950795 ~ 14981580 (-)
XLOC_006523 sfxn5a coding upstream 91586 15020822 ~ 15082024 (-)
XLOC_006524 rab11fip5a coding upstream 162028 15091264 ~ 15142280 (-)
XLOC_006525 NA coding upstream 527440 15456676 ~ 15457624 (-)
XLOC_006526 BX511166.1 coding upstream 645901 15575137 ~ 15580152 (-)
XLOC_006471 BX537274.2 misc downstream 4650439 10264741 ~ 10264905 (-)
XLOC_006338 rn7sk misc downstream 14089119 825904 ~ 826225 (-)
XLOC_006514 NA non-coding downstream 1174784 13737542 ~ 13740560 (-)
XLOC_006513 CR788322.4 non-coding downstream 1244807 13670440 ~ 13670537 (-)
XLOC_006536 NA non-coding upstream 1331415 16260651 ~ 16261573 (-)
XLOC_006537 BX323467.1 non-coding upstream 1378531 16307767 ~ 16307883 (-)

Expression


Co-expression Network