XLOC_006542 (vdac2)


Basic Information

Item Value
gene id XLOC_006542
gene name vdac2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 17714296 ~ 17729474 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012661
GCCACACATCTGTTCCTGGCCGTTAGCAATTACCGTCAGGCAGAGGTGAGGACAGCCCGGGGTCCTTGAGCGGGAGGCTGTCGGCACGGGTGTGTTACATTACAGTCTCCTTCAGTTCGCCCTCCAACTGGCCAGACCCTCCACATTGGCTCAGCGCTGGGAATAACTTCAGCAGCCGCGTTTCAATAACCGCACTCCACTCCTTTTAACAGATAAAATGGCCGTTCCCCCAGCATATGCTGATCTTGGCAAATCTGCCAAAGACATCTTTAACAAAGGATATGgattcgGTATGGTGAAGCTCGATGTCAAGACAAAATCAGCCAGTGGAGTGGAATTCAAGACCTCTGGTTCCTCCAACACTGACACCAGCAAAGTGGTTGGGAGCCTGGAAACCAAATACAAGAGGTCTGAATATGGCCTGACCTTCACAGAGAAGTGGAATACCGACAACACCCTGGGCACAGAGATCAACATTGAAGACCAGatCGCAAAGGGACTGAAACTGACCTTTGACACAACCTTCTCACCAAACACAGGGAAAAAGAGTGGCAAAGTCAAGACCGCATACAAGCGTGAGTTTGTCAACCTGGGATGTGATGTTGACTTCGACTTTGCCGGCCCAACTATCCACGGCGCTGCAGTGGTCGGTTACGAAGGATGGCTCGCCGGTTACCAGATGTCCTTCGACACCGCCAAGTCCAAGATGACCCAGAACAACTTTGCTGTAGGCTACAAAACGGGAGACTTCCAGCTGCACACTAATGTTAATGATGGCTCAGAGTTTGGTGGTTCCATCTATCAAAAAGTGAGTGATAAGCTGGAGACAGCGGTGAATCTGGCCTGGACAGCAGGAAGCAACAGCACACGCTTTGGAATTGCTGCCAAGTATCAGCTGGACAAAGACGCCTCCATCAGTGCTAAAGTGAATAACACCAGCCTTGTTGGTGTTGGTTACACTCAATCTCTGAGACCAGGTATCAAGTTGACCCTGTCTGCCCTGGTTGATGGGAAGAGCATCAATTCCGGTGGCCACAAGCTGGGCTTGGGCCTGGAGCTGGAGGCTTAAACCTGCTTCTGCTGAACATCAGGGACAAGGGAATATCAGAGAAATCTGGCCTTAAATCTAACTCCAGCAGCAACCAGCAGGGGGAATCGGGATGGGATGTGTGCAAAGGCTCATCAAAAGCGATCATGTCATGTGGTTTCTTTTTCGTCCCCTTCAGGTCCTTATGTTTGTTTTTCGTTTGTAGTTGTTCTCTCATAGACATTCAGCTACAAATTAATTTGGCCATCCCTCTCCAGCACTTCCACAGTAATGAAATGCGCTCTGGGATAGAGGGCATCTGTGGCGTCCTGATGTGTTGCTCCCTCTTCAGTTAGACGGTGGTGGGTTTGTGACAAAACTGTCTCTGATTTCATCCTTTGTATTGTATCTGATATTCCTTCGTCGTCTGATTGCGATTCAAGCAAACCACTTTACTCGATATTAAAGGTTCTACCTGATATTATTTAAATACTGTTATACCGTTTTCTTCTTTCCATGCACGCAAGGACGAGCTTTAAGCAGTTTACTTTCCCTCGGGCAGCCATCCAGAGTTTATCTTGCAGGTGAAGTCTGCCCTTGAGCTGAGCAGTTTTTGGGTAGCCTAATGGGGTGGTGAGTGCTGTTGCCCGTGAGCTGGCATGGCTGGCCTTCTGTTTTTCATTTGCAGCACAGATGACTCTCCGTGGCTCCCTGTGATGGCGGGACGGGTCTTGTGGGTGTGGTTTGAGTTCAGTACCTTTTGCTCCCGGTGTTGCCCTGATTCCCATGCTTTACAACACCTCAGAGGTCCTTATGTGTATGTTTGAACTTTTCAATAAACTCTTTGAACACATCTTACCATA
>TCONS_00012662
ATGGCCGTTCCCCCAGCATATGCTGATCTTGGCAAATCTGCCAAAGACATCTTTAACAAAGGATATGgattcgGTATGGTGAAGCTCGATGTCAAGACAAAATCAGCCAGTGGAGTGGAATTCAAGACCTCTGGTTCCTCCAACACTGACACCAGCAAAGTGGTTGGGAGCCTGGAAACCAAATACAAGAGGTCTGAATATGGCCTGACCTTCACAGAGAAGTGGAATACCGACAACACCCTGGGCACAGAGATCAACATTGAAGACCAGatCGCAAAGGGACTGAAACTGACCTTTGACACAACCTTCTCACCAAACACAGGGAAAAAGAGTGGCAAAGTCAAGACCGCATACAAGCGTGAGTTTGTCAACCTGGGATGTGATGTTGACTTCGACTTTGCCGGCCCAACTATCCACGGCGCTGCAGTGGTCGGTTACGAAGGATGGCTCGCCGGTTACCAGATGTCCTTCGACACCGCCAAGTCCAAGATGACCCAGAACAACTTTGCTGTAGGCTACAAAACGGGAGACTTCCAGCTGCACACTAATGTTAATGATGGCTCAGAGTTTGGTGGTTCCATCTATCAAAAAGTGAGTGATAAGCTGGAGACAGCGGTGAATCTGGCCTGGACAGCAGGAAGCAACAGCACACGCTTTGGAATTGCTGCCAAGTATCAGCTGGACAAAGACGCCTCCATCAGTGCTAAAGTGAATAACACCAGCCTTGTTGGTGTTGGTTACACTCAATCTCTGAGACCAGGTATCAAGTTGACCCTGTCTGCCCTGGTTGATGGGAAGAGCATCAATTCCGGTGGCCACAAGCTGGGCTTGGGCCTGGAGCTGGAGGCTTAAACCTGCTTCTGCTGAACATCAGGGACAAGGGAATATCAGAGAAATCTGGCCTTAAATCTAACTCCAGCAGCAACCAGCAGGGGGAATCGGGATGGGATGTGTGCAAAGGCTCATCAAAAGCGATCATGTCATGTGGTTTCTTTTTCGTCCCCTTCAGGTCCTTATGTTTGTTTTTCGTTTGTAGTTGTTCTCTCATAGACATTCAGCTACAAATTAATTTGGCCATCCCTCTCCAGCACTTCCACAGTAATGAAATGCGCTCTGGGATAGAGGGCATCTGTGGCGTCCTGATGTGTTGCTCCCTCTTCAGTTAGACGGTGGTGGGTTTGTGACAAAACTGTCTCTGATTTCATCCTTTGTATTGTATCTGATATTCCTTCGTCGTCTGATTGCGATTCAAGCAAACCACTTTACTCGATATTAAAGGTTCTACCTGATATTATTTAAATACTGTTATACCGTTTTCTTCTTTCCATGCACGCAAGGACGAGCTTTAAGCAGTTTACTTTCCCTCGGGCAGCCATCCAGAGTTTATCTTGCAGGTGAAGTCTGCCCTTGAGCTGAGCAGTTTTTGGGTAGCCTAATGGGGTGGTGAGTGCTGTTGCCCGTGAGCTGGCATGGCTGGCCTTCTGTTTTTCATTTGCAGCACAGATGACTCTCCGTGGCTCCCT

Function

symbol description
vdac2 Enables channel activity and identical protein binding activity. Acts upstream of or within calcium import into the mitochondrion; fin regeneration; and regulation of heart contraction. Located in plasma membrane. Is expressed in several structures, including lens; pectoral fin; pericardial region; solid lens vesicle; and ventral mesoderm. Orthologous to human VDAC2 (voltage dependent anion channel 2).

GO:

id name namespace
GO:0098656 anion transmembrane transport biological_process
GO:0055085 transmembrane transport biological_process
GO:0036444 calcium import into the mitochondrion biological_process
GO:0031101 fin regeneration biological_process
GO:0008016 regulation of heart contraction biological_process
GO:0005886 plasma membrane cellular_component
GO:0005741 mitochondrial outer membrane cellular_component
GO:0015267 channel activity molecular_function
GO:0042802 identical protein binding molecular_function
GO:0008308 voltage-gated anion channel activity molecular_function

KEGG:

id description
ko04020 Calcium signaling pathway
ko04022 cGMP-PKG signaling pathway
ko04216 Ferroptosis
ko04217 Necroptosis
ko04218 Cellular senescence
ko04613 Neutrophil extracellular trap formation
ko04621 NOD-like receptor signaling pathway
ko04979 Cholesterol metabolism
ko05208 Chemical carcinogenesis - reactive oxygen species
ko05166 Human T-cell leukemia virus 1 infection
ko05010 Alzheimer disease
ko05012 Parkinson disease
ko05016 Huntington disease
ko05017 Spinocerebellar ataxia
ko05020 Prion disease
ko05022 Pathways of neurodegeneration - multiple diseases
ko05415 Diabetic cardiomyopathy
ko03029 Mitochondrial biogenesis
ko04040 Ion channels

ZFIN:

id description
ZDB-GENE-030131-845 Enables channel activity and identical protein binding activity. Acts upstream of or within calcium import into the mitochondrion; fin regeneration; and regulation of heart contraction. Located in plasma membrane. Is expressed in several structures, including lens; pectoral fin; pericardial region; solid lens vesicle; and ventral mesoderm. Orthologous to human VDAC2 (voltage dependent anion channel 2).

Ensembl:

ensembl_id ENSDARG00000013623

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012661 False 1890 mRNA 0.49 9 17714296 17729474
TCONS_00012662 True 1523 mRNA 0.48 8 17714446 17723417

Neighbor

gene id symbol gene type direction distance location
XLOC_006541 NA coding downstream 20477 17686484 ~ 17693819 (-)
XLOC_006540 NA coding downstream 183760 17494297 ~ 17530536 (-)
XLOC_006539 lrmda coding downstream 249642 16922705 ~ 17464654 (-)
XLOC_006538 NA coding downstream 835226 16868380 ~ 16879070 (-)
XLOC_006537 BX323467.1 coding downstream 1406413 16307767 ~ 16307883 (-)
XLOC_006543 march8 coding upstream 22392 17751866 ~ 18011208 (-)
XLOC_006544 zfand4 coding upstream 290235 18019709 ~ 18069421 (-)
XLOC_006545 washc2c coding upstream 343737 18073211 ~ 18122333 (-)
XLOC_006546 alox5a coding upstream 398801 18128275 ~ 18174864 (-)
XLOC_006547 slc25a16 coding upstream 449622 18179096 ~ 18195942 (-)
XLOC_006471 BX537274.2 misc downstream 7449391 10264741 ~ 10264905 (-)
XLOC_006338 rn7sk misc downstream 16888071 825904 ~ 826225 (-)
XLOC_006536 NA non-coding downstream 1452723 16260651 ~ 16261573 (-)
XLOC_006551 CR932438.1 non-coding upstream 915416 18644890 ~ 18645005 (-)
XLOC_006552 CR932438.2 non-coding upstream 920018 18649492 ~ 18649682 (-)
XLOC_006554 CR932361.2 non-coding upstream 985836 18715310 ~ 18715426 (-)
XLOC_006556 NA non-coding upstream 1280698 19010172 ~ 19016833 (-)
XLOC_006557 NA non-coding upstream 1546699 19276173 ~ 19277332 (-)

Expression


Co-expression Network