htr2aa (htr2a,htr2aa,LOC107673120,LOC107709424,LOC107601068,LOC107724025,LOC107675342)


Basic Information

Item Value
gene id htr2aa
gene name htr2a,htr2aa,LOC107673120,LOC107709424,LOC107601068,LOC107724025,LOC107675342
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056707.1
NCBI id CM032076.1
chromosome length 26426558
location 12482174 ~ 12507487 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043248306.1
ACCTGAGGAACTTTCACTAAACCCCTGACTCACACTTCagtctctctccccctctcgctctccctctctctctctctcagcacaGCTGGATTGAACAGAATGATCACTGGCTTGAGGAGGACCAGAATCTGCTAGCTCCGCACACCGCCAGAGAGAGCGGAGAGAGGGAGCCAGAGAGAGCGTGCGCTCAACTATCAGGTCATCCAGCTCGTAAAATCCGTTGTGTTCTGACAACGAGAACAGAGAGGAGCAAGAAGACTTCACTTAACAGACACAACACACTCTGTGCTTTCAGAAATGCACGGATTATGGGAACATTTGATCGATGCGCCTTCCATTCTCTGCTTTTCAGGCTTTTTGGTGACTGTAAAAGAGTAGCACGAAGACTTCAGGAGTGTTTTCAAAGAGGACAGAATGAAGAAATCCTCTGGACTCAACGGCTGGATGAAAGATGCTATGAAGAAAAGAAGGATACATGACCTCTAACCGAACTTGGGAGGTAACAAACTTTTGTCTTTAAGAGTCTAGCAGCGTTATTAAGGGACATTATGAACTTGCATGCcaacatttcaaaacctgtGCCTAAAAGCATCTTCACCTCTTCGAACCTCATGCCCTTTGACCCTGACACCTGGACACCGAGCCCGGACATCATGCTGGGTAATGTGGTTCGTAACAGTTCCATAGGCTGTAACAGAAGTTGGGCTGACACCGAAGCATCTCTCTTTCCCAATTTATCCATCAGCAGCACTTCCAGTGAAAAAACAGAACCGCTGTCATGGCAAAGGTGCAACGGCGAGACAAGCAAAGAGGAATTAGTTCGGAAAAACTGGGCTGCGTTACTGATTTTGGTTGTGGTCATTATTACGGTTACCGGgaacattttagtaatcatGGCTGTCAATCTGGAACGAAAACTGCAAAATGCCACCAATTACTTTCTCATGTCACTGGCTGTGGCAGATATGCTTCTGGGACTTCTGGTCATGCCTGTCTCCATGGTGACCATTGTGTATGGTTACTCCTGGCCCCTGCCTGCATCACTGTGTCCCATGTGGATCTACTTGGATGTTCTCTTTTCCACCGCCTCCATCATGCACCTGTGCGCTATCTCGCTGGACCGTTATGTGGCCATCCGTAACCCCATCCGACACAATCGGTCAAACTCACGCTCCCGCGCCCGGGCCAAGATCACGGCCGTGTGGACCATCTCAGCAGGCATCTCCATGCCAATCCCAGTGCTGGGTCTGCGCGATCACACCAAAGTTTTCAAGGATGGCAGCTGCCTATTGACTGACAACTCTTTCGTGTTGATTGGGTCCTTTGTGGCTTTCTTTGTGCCATTGACCATTATGGTGGTGACCTACTTCCTGACTATCAGCGCTCTGCAGAGTGAGGCGACTCTCTGCCTCGACCAACTGGTGCCCAGGCCCAAATGGAGCGCAGGATTCACTCTCAACTTCCTCCCCGGACCCTCGTTCTCGCCCTCAGAGAAAAAGCTGTTCTTGCGGCGCTCGTTGAGCCGAGAGGCGGGGGCAGACTCAGGGGTTGTGACCCCACCTTTCGGACGGCACACGGTGCAGACCATCAGCAACGAGCAAAAAGCCTCCAAAGTTCTGGGCGTGGTTTTCTTCCTGTTCGTGGTCATGTGGTGTCCGTTTTTCATCACTAATGTATTAGTGGTGGTTTGCGAGCCGGTGACGTGCGACGCTGATGTGATGAACAGACTGCTGAATGTGTTCGTGTGGGTCGGTTACCTTTCCTCCGCCGTTAACCCGCTGGTTTACACGCTCTTTAACAAGACTTACCGCTCAGCCTTCGCCAGATACATCCGATGCCAGTTTCACGAGGAGAAGAAACCGCTACAACTAATTCTGGTCAACACCATTCCACCGCTGGCCTATCAGTCCACACACCTGCCGCTCACTGGATCAATAGGCAATGGGGATTTCTCTCTGCCCCTTCCCAATAAAAACCACCATCTGTccaaaagcagcaaaaatgaGAGTGTCAGCTGCTTGTGAATTCACTCGGCGAACTCGCAAAATGCCAGACGTAACCCTGGATTTTCTTCTGGGTTTCATGTTTGGCATTCTCTCCGTCTTACCTTTGCAGAAATCAGTTATGATTGGTCTAAAGTATTAGTAGTCAAAGCCCAACTGCATCAATGAACGGACGGCTTCACGATCTATGACTGTATCACAGCGTACTCACACATCAAAAGAACTCTGATCGGGATTTGTCCTGACTGCAAATGTCAGTTGAATCAATGGGATGAAACCTCTCTGgttataaaaattgtatataagtGTTAAGTCAAAGTTTAAGTCAAAGTTAGTTTTTTATGTAGCACTTTATATGCAGAGAGTGAAGTCTAAATTCATGGGAGATCAACAgtgttttgtttacagcatCTGTTTTTTGAAAACAAGCGTGGTTGATGTGACTTGAGTTTTTGTACTGCGTCAAACGACTGAGATGCTGTAGCCTCGTATAAGCTGACTTGTGTGCTGCTGATTTATCATTTTAGCAGACATTTGTATTACTAGTCACTGAATCCAGACACAGAAGGACAAGATAGTGGTTTTAGGACCTTACCTTAAAAAGTATGAAACAGTTTCTGGGATCAAAGCATAAGGaccacttttatttaattattagaagtgacttttttaaatgattcctATTATATGATAAgaacaatgataaaaaaaatcatgcctaTAGAAGCCTGTTTCCACttcagagtaaaataaaataagtaaaattgtGAGActatgttttaaataagaaatgtagGGCCCTATCATATATTGGTGCGAGGCGCAGCGCAAGTGAGTTTGCTAGTTTCAGTCTGACGCGTTTAActagcaaatgcatttgcacCCTTGTGCTTGCTGGtccaaaaaaaaaggtgttttcagGAGCATTGGTGGTGCGTTGCtattttaatgaactgaaaataGGCTGAAAAAAGAAACCTGGTCTAAAGTCTAATATCAATgcgcagtattttttttgttgctatttATAATGGGCGGGTCCACAGCGCGCGTTGACTTATCGTAGgctacatacaaaaaaaatgtaatgatggaCAGTCAATGAGTGTTTTCAGAATTAGCCTTGCGCACGAGCAAATCGGTTTCTTTGTTTGAGAAGAGTTCAGATTTTTGCCAAAAAAGTCCACCATGGCGCGAGCGCAACTCGATGATACTCTGATTGATTTAGTGCACGTTATGCCCAAAAAACACCCATTATTtaagagaaaagagaaacaatCCATTTGGACTATGCGCCCGTGCGCACAGACcgttttaaaatagcaaaagtggATTTGGACACGAGTCCTGAGTGCACCTGCACCGTGAACTTTAGATTTTGGGccctatttttacattttcaaatacaaagCTATGTATGAGACATGTATGGGGGGGGTCACAaatgctgcattcatttgattaaaaaaaatacagtaaaagtaatattgtaaaatattgttattgtttaaaattactgttttctatggtaatgtattttaaaatgtcatttggtgGCAGAGCTTTCAGTATCCATTACTGTatccttcagtgtcacatgatcctttagaaacaGTTCTAATCTGCTGATTTGGtgaataagaaataattattatcaatgttgaaacaCTTAATATTGTCGTGGAAACGTTTAATTTTTTCAGtgttctttaatgaatagaacttttttaaaaaacagcatttaaaatggaaatctttGGTAACATGGTAAATGTCGCTTTTGGtctatttaatgcatccttgctgaataaaagtatcagtttctttttttaaaaaaaagcaacaaaacaaatgtgcagAGCATATAGTATGGTTTAAATCTATAGCTGTTACTCTGAGGaggaaatgggcttccatagaAACTTTCTCGGATAAATCTTTAAAAGACTACAATCCAGATTAGAAAGCATGCTGTTTGAGCAGTATTTTCCTGGTGGTAAACATCAGCAGAACCAGCCAAAACTAGAGGAAACCAGCAGAAACCAGCCTGGCGCAGCATGAAAAGTctaagctttttatttcaaaagggAACCGTATCTGCTTTTCACCCTGTCATTTTGGACCGATCAAAAACAATTTCTGAGACCTTTTGGCGTTGCACATATTGTTCAGGTAGTGGCAGTATTCAAACCCAACGCTTACATTTGTcagatttgacatttttgtttttttttgaaaacgtgCTTTTAAGAAGACCTGTaagtttttggttttgaaaatgtacctCTGGATTCAGGGTTCCATGGCAACACAAAGGGTTCAGATCTCAGCACCTCGTGAAAACCTCTGATCTGTTTTCTGATTCTATTTCCAGTGTCTGAGTTGACAgcgctgctgttgttgttgttgttgttatggtGATGGTCATAAACTTGT
>XM_043248307.1
ACCTGAGGAACTTTCACTAAACCCCTGACTCACACTTCagtctctctccccctctcgctctccctctctctctctctcagcacaGCTGGATTGAACAGAATGATCACTGGCTTGAGGAGGACCAGAATCTGCTAGCTCCGCACACCGCCAGAGAGAGCGGAGAGAGGGAGCCAGAGAGAGCGTGCGCTCAACTATCAGGTCATCCAGCTCGTAAAATCCGTTGTGTTCTGACAACGAGAACAGAGAGGAGCAAGAAGACTTCACTTAACAGACACAACACACTCTGTGCTTTCAGAAATGCACGGATTATGGGAACATTTGATCGATGCGCCTTCCATTCTCTGCTTTTCAGGCTTTTTGGTGACTGTAAAAGAGTAGCACGAAGACTTCAGGAGTGTTTTCAAAGAGGACAGAATGAAGAAATCCTCTGGACTCAACGGCTGGATGAAAGATGCTATGAAGAAAAGAAGGATACATGACCTCTAACCGAACTTGGGAGGTTACTCCTGGCCCCTGCCTGCATCACTGTGTCCCATGTGGATCTACTTGGATGTTCTCTTTTCCACCGCCTCCATCATGCACCTGTGCGCTATCTCGCTGGACCGTTATGTGGCCATCCGTAACCCCATCCGACACAATCGGTCAAACTCACGCTCCCGCGCCCGGGCCAAGATCACGGCCGTGTGGACCATCTCAGCAGGCATCTCCATGCCAATCCCAGTGCTGGGTCTGCGCGATCACACCAAAGTTTTCAAGGATGGCAGCTGCCTATTGACTGACAACTCTTTCGTGTTGATTGGGTCCTTTGTGGCTTTCTTTGTGCCATTGACCATTATGGTGGTGACCTACTTCCTGACTATCAGCGCTCTGCAGAGTGAGGCGACTCTCTGCCTCGACCAACTGGTGCCCAGGCCCAAATGGAGCGCAGGATTCACTCTCAACTTCCTCCCCGGACCCTCGTTCTCGCCCTCAGAGAAAAAGCTGTTCTTGCGGCGCTCGTTGAGCCGAGAGGCGGGGGCAGACTCAGGGGTTGTGACCCCACCTTTCGGACGGCACACGGTGCAGACCATCAGCAACGAGCAAAAAGCCTCCAAAGTTCTGGGCGTGGTTTTCTTCCTGTTCGTGGTCATGTGGTGTCCGTTTTTCATCACTAATGTATTAGTGGTGGTTTGCGAGCCGGTGACGTGCGACGCTGATGTGATGAACAGACTGCTGAATGTGTTCGTGTGGGTCGGTTACCTTTCCTCCGCCGTTAACCCGCTGGTTTACACGCTCTTTAACAAGACTTACCGCTCAGCCTTCGCCAGATACATCCGATGCCAGTTTCACGAGGAGAAGAAACCGCTACAACTAATTCTGGTCAACACCATTCCACCGCTGGCCTATCAGTCCACACACCTGCCGCTCACTGGATCAATAGGCAATGGGGATTTCTCTCTGCCCCTTCCCAATAAAAACCACCATCTGTccaaaagcagcaaaaatgaGAGTGTCAGCTGCTTGTGAATTCACTCGGCGAACTCGCAAAATGCCAGACGTAACCCTGGATTTTCTTCTGGGTTTCATGTTTGGCATTCTCTCCGTCTTACCTTTGCAGAAATCAGTTATGATTGGTCTAAAGTATTAGTAGTCAAAGCCCAACTGCATCAATGAACGGACGGCTTCACGATCTATGACTGTATCACAGCGTACTCACACATCAAAAGAACTCTGATCGGGATTTGTCCTGACTGCAAATGTCAGTTGAATCAATGGGATGAAACCTCTCTGgttataaaaattgtatataagtGTTAAGTCAAAGTTTAAGTCAAAGTTAGTTTTTTATGTAGCACTTTATATGCAGAGAGTGAAGTCTAAATTCATGGGAGATCAACAgtgttttgtttacagcatCTGTTTTTTGAAAACAAGCGTGGTTGATGTGACTTGAGTTTTTGTACTGCGTCAAACGACTGAGATGCTGTAGCCTCGTATAAGCTGACTTGTGTGCTGCTGATTTATCATTTTAGCAGACATTTGTATTACTAGTCACTGAATCCAGACACAGAAGGACAAGATAGTGGTTTTAGGACCTTACCTTAAAAAGTATGAAACAGTTTCTGGGATCAAAGCATAAGGaccacttttatttaattattagaagtgacttttttaaatgattcctATTATATGATAAgaacaatgataaaaaaaatcatgcctaTAGAAGCCTGTTTCCACttcagagtaaaataaaataagtaaaattgtGAGActatgttttaaataagaaatgtagGGCCCTATCATATATTGGTGCGAGGCGCAGCGCAAGTGAGTTTGCTAGTTTCAGTCTGACGCGTTTAActagcaaatgcatttgcacCCTTGTGCTTGCTGGtccaaaaaaaaaggtgttttcagGAGCATTGGTGGTGCGTTGCtattttaatgaactgaaaataGGCTGAAAAAAGAAACCTGGTCTAAAGTCTAATATCAATgcgcagtattttttttgttgctatttATAATGGGCGGGTCCACAGCGCGCGTTGACTTATCGTAGgctacatacaaaaaaaatgtaatgatggaCAGTCAATGAGTGTTTTCAGAATTAGCCTTGCGCACGAGCAAATCGGTTTCTTTGTTTGAGAAGAGTTCAGATTTTTGCCAAAAAAGTCCACCATGGCGCGAGCGCAACTCGATGATACTCTGATTGATTTAGTGCACGTTATGCCCAAAAAACACCCATTATTtaagagaaaagagaaacaatCCATTTGGACTATGCGCCCGTGCGCACAGACcgttttaaaatagcaaaagtggATTTGGACACGAGTCCTGAGTGCACCTGCACCGTGAACTTTAGATTTTGGGccctatttttacattttcaaatacaaagCTATGTATGAGACATGTATGGGGGGGGTCACAaatgctgcattcatttgattaaaaaaaatacagtaaaagtaatattgtaaaatattgttattgtttaaaattactgttttctatggtaatgtattttaaaatgtcatttggtgGCAGAGCTTTCAGTATCCATTACTGTatccttcagtgtcacatgatcctttagaaacaGTTCTAATCTGCTGATTTGGtgaataagaaataattattatcaatgttgaaacaCTTAATATTGTCGTGGAAACGTTTAATTTTTTCAGtgttctttaatgaatagaacttttttaaaaaacagcatttaaaatggaaatctttGGTAACATGGTAAATGTCGCTTTTGGtctatttaatgcatccttgctgaataaaagtatcagtttctttttttaaaaaaaagcaacaaaacaaatgtgcagAGCATATAGTATGGTTTAAATCTATAGCTGTTACTCTGAGGaggaaatgggcttccatagaAACTTTCTCGGATAAATCTTTAAAAGACTACAATCCAGATTAGAAAGCATGCTGTTTGAGCAGTATTTTCCTGGTGGTAAACATCAGCAGAACCAGCCAAAACTAGAGGAAACCAGCAGAAACCAGCCTGGCGCAGCATGAAAAGTctaagctttttatttcaaaagggAACCGTATCTGCTTTTCACCCTGTCATTTTGGACCGATCAAAAACAATTTCTGAGACCTTTTGGCGTTGCACATATTGTTCAGGTAGTGGCAGTATTCAAACCCAACGCTTACATTTGTcagatttgacatttttgtttttttttgaaaacgtgCTTTTAAGAAGACCTGTaagtttttggttttgaaaatgtacctCTGGATTCAGGGTTCCATGGCAACACAAAGGGTTCAGATCTCAGCACCTCGTGAAAACCTCTGATCTGTTTTCTGATTCTATTTCCAGTGTCTGAGTTGACAgcgctgctgttgttgttgttgttgttatggtGATGGTCATAAACTTGT

Function

symbol description
htr2aa Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; release of sequestered calcium ion into cytosol; and response to drug. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in several cellular components, including axon; caveola; and presynapse. Predicted to be integral component of membrane. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; anorexia nervosa; major depressive disorder; obesity; and obsessive-compulsive disorder. Orthologous to human HTR2A (5-hydroxytryptamine receptor 2A).
htr2a Enables several functions, including 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding activity; Gq/11-coupled serotonin receptor activity; and serotonin binding activity. Involved in several processes, including activation of phospholipase C activity; phosphatidylinositol 3-kinase signaling; and positive regulation of phosphatidylinositol biosynthetic process. Located in plasma membrane. Part of G protein-coupled serotonin receptor complex. Implicated in several diseases, including alcohol use disorder; anorexia nervosa; major depressive disorder; obesity; and obsessive-compulsive disorder.

NR:

description
5-hydroxytryptamine receptor 2A-like

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0005886 plasma membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004930 G protein-coupled receptor activity molecular_function

KEGG:

id description
K04157 HTR2; 5-hydroxytryptamine receptor 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043248306.1 True 4439 mRNA 0.43 3 12482174 12507487
XM_043248307.1 False 3921 mRNA 0.43 3 12482174 12507487

Neighbor

gene id symbol gene type direction distance location
med4 med4,LOC107724027,LOC107673119,LOC107601074,LOC107709409,LOC107675337 coding upstream 26046 12453126 ~ 12456128 (+)
acvr2aa LOC107709421,LOC107673126,LOC107675352,LOC107601072 coding upstream 52818 12392286 ~ 12429356 (+)
LOC122351360 arhgap15,LOC107673132,LOC107709415,LOC107555858,LOC107563181,LOC107711394,LOC107675340 coding upstream 326201 12122231 ~ 12155973 (+)
arhgap15 arhgap15,LOC107673132,LOC107709415,LOC107555858,LOC107563181,LOC107711394,LOC107675340 coding upstream 395666 12046474 ~ 12086508 (+)
nepro si:dkey-22a1.3,LOC107733637 coding upstream 1096180 11382392 ~ 11385994 (+)
esd esd,LOC107675365,LOC107601075,LOC107709410,LOC107724032 coding downstream 6809 12514296 ~ 12518069 (+)
rubcnl rubcnl,LOC107709411,LOC107673128 coding downstream 47126 12554613 ~ 12560394 (+)
dnah7 dnah7 coding downstream 54972 12562459 ~ 12619422 (+)
LOC122352187 NA coding downstream 223349 12730836 ~ 12730962 (+)
LOC122351844 sf3b1,LOC107731751,LOC107659892,LOC107719800,LOC107690614,LOC107595847,LOC107569635 coding downstream 270083 12777570 ~ 12787437 (+)
G69625 NA non-coding upstream 24676 12457264 ~ 12457498 (+)
G69578 NA non-coding upstream 159642 12322251 ~ 12322532 (+)
G69539 NA non-coding upstream 281577 12199934 ~ 12200597 (+)
G69518 NA non-coding upstream 472252 11979781 ~ 12009922 (+)
G69483 NA non-coding upstream 1058857 11420205 ~ 11423317 (+)
G69659 LOC107709425,LOC107724026 non-coding downstream 10802 12518289 ~ 12526873 (+)
G69706 NA non-coding downstream 157525 12665012 ~ 12724840 (+)
G69718 NA non-coding downstream 265847 12773334 ~ 12773850 (+)
G69723 NA non-coding downstream 330232 12837719 ~ 12840151 (+)
G69783 NA non-coding downstream 598793 13106280 ~ 13106757 (+)
epc2 epc2,itm2b,LOC107709422,LOC107724031,LOC107675331,LOC107673124,LOC107709423 other upstream 29809 12434988 ~ 12452365 (+)
G69527 arhgap15,LOC107563181,LOC107673132,LOC107709415,LOC107555858,LOC107675340,LOC107711394 other upstream 326370 12046499 ~ 12155804 (+)
LOC122352020 uggt2,LOC107600415,LOC107720140,LOC107663813,LOC107655477,LOC108430493,LOC107706079,LOC108266228 other upstream 992025 11465604 ~ 11490149 (+)
creb1b creb1b,creb1,LOC107598164,LOC107738506,LOC107698524,LOC107663917 other upstream 1451765 11021736 ~ 11030409 (+)
il1rapl1a il1rapl1a,LOC107655515,LOC107600393,LOC107663843,LOC107555221,LOC107706095 other upstream 2086944 10328731 ~ 10395230 (+)
G69670 LOC107673130,LOC107555834,LOC107709428,LOC107724029,LOC107675357 other downstream 120048 12627535 ~ 12629535 (+)
LOC122351618 clasp1a,clasp2,LOC107741904,LOC107714287,LOC107673735,LOC107596084,LOC107706129,LOC107696541,LOC107669402 other downstream 224811 12732298 ~ 12803408 (+)
G69755 NA other downstream 477381 12984868 ~ 12985978 (+)
G69834 col6a3,LOC107685998,LOC107567775,LOC107670696 other downstream 782206 13289693 ~ 13304591 (+)
ccnt2a ccnt2a,LOC107658298,LOC107725237,LOC107723659,LOC107684218,LOC107555058,LOC107555362 other downstream 1168676 13676163 ~ 13684835 (+)

Expression


Co-expression Network