appb (appb,LOC107597486,LOC107748127,LOC107595805,LOC107756757,LOC107695460,LOC108426075)


Basic Information

Item Value
gene id appb
gene name appb,LOC107597486,LOC107748127,LOC107595805,LOC107756757,LOC107695460,LOC108426075
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056707.1
NCBI id CM032076.1
chromosome length 26426558
location 17299245 ~ 17315818 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043248528.1
GTGCAGTCGCGCATTCTCACAAAGCACAACCGAGCACAGACGATAGGGGAACACGGAGCAGAAGATCGACACAGAAAACCCTGATCCGCTCGGGACGTTTATCCATCAGGACGTGCTGCGTTTGGGAACACGGCCATGGGTATGGACCGTACGGTATTCCTGCTGCTAATGCTGACGACTCTGTCGCTCGCCATCGAGGTGCCATCGGATGACTCGGTGGGCTTGTTGGCGGAGCCCCAGGTGGCCATGTTTTGTGGGAAACTCAACATGCATATCAACATCCAGAGTGGCAAGTGGGAGCCGGATCCAACTGGCACCAAAGGCTGCATCGGCACCAAAGAGGGCATCCTTCAGTACTGCCAAGAGGTATACCCAGACCTCCAGATCACTAACGTGGTGGAGGCTAACCAGCCCGTCAGCATCCAGAACTGGTGCAAAATGGGTCGTCACCAGTGCCGCAGTCACACGCGCATTGTGGTCCCCTACCGCTGCCTGGTTGGGGAGTTTGTCAGCGATGCCCTCCTCGTCCCAGATAAATGCAAGTTCCTGCACCAAGAGCGAATGGACATGTGCGAGAGTCATCTGCACTGGCACACAGTGGCCaaagagTCCTGCGGCGATCGTTCCATGAATCTCCATGACTACGGCATGCTGCTGCCGTGCGGCATCGACCGTTTCCGTGGTGTGGAGTTTGTGTGCTGCCCTATGGAGGAGCAGAAGGAGTTAGACAGcgaggagcaggaggaggccAACTCAGATGTGTGGTGGGGCGGCGCAGAGGCCGAGTATACTGACGGCAGCATACTGAAAGAACAGGCCCCGACTAAACCTGAGCCTGCTGTGACTGAGGATGATGAGGATATCAAcaatgaggaagaggaagtctGGGATAATGATGAAGATGGTGATGGTGAAGATGATGACGACGAAGAAGATGACGATGAAGACACTACTGATGAACAAGACACCAGTGAGCAGACCTCCAACGTTGCCATGACAACCACCACCACTACCACAACAGAGTCTATAGAGGAGGTTGTGCGAGCGGTATGCTGGGCCCCACCTCGGTCGGGGCCGTGCCATGCCAAGCTATCCCGCTGGTATTTTGTGGCGCAGACGGGCCGATGCGCCCCCTTCATGTTTGGGGGCTGTGGGGGTAACCGCAATAACTTTGAATCTGAGGAGTACTGCATGGCTgtctgcagcagcagcagcgtgtTGCCGACCGTGGCTCCGAGCCCTGCTGATGCTGTGGATCGTTACCTGGAAGCTCCAGGAGACGTGAATGAGCACACCCGCTTCCAAAAGGCAAAGGAGAGCCTGGAGGCCAAACACAGAGATAAAATGTCAGAGGTGATGAGAGAATGGGAGGAGGCAGAGAGACAGGCGAAGAACCTCCCCCGTGCTGATAAGAAGACCATAATTCAGCGCTTCCAGGAGAAGGTGGAGGCGTTGGAGAAGGAAGCGGCCGGGGAGAGGCAGCAGCTGGTAGAAACCCACATGGCACGCGTGGAAGCTCTGCTGAACGACCGCCGCCGCCAGGCTCTGGAAAGCTACCTTAGCGCCCTGCAATCTGACCAGCCTCGGCCTCGGCAGGTCCTCAATCTGTTGAAGAAGTACATACGAGCGGAGCAGAAGGACAGGCAGCACACGCTCAAACACTTTGAGCACGTGCGAGAGGTGGATCCCAAGAAGGCTTCTCAGATTCGGCCTTTTGTAATGACCCACCTGCGCGTGATTGAAGAACGCATGAACCAATCTTTGGGGTATCTCTACAAGGTGCCGCAGGTGGCTAATGAAATCCAGGACCAAGTGGcATTGCTGATTCAACATGACCAGGCTGAAGTTACCCAACAGCTGTCGTCTCTCCAGAGTAAGATGAGGGTGAGCTACGGGAACGACGCTCTGATGCCCGACCTGCCGGACAGCACCACCCCGCTGGACACCTTGCCACCGGAGCAGGACGGCCTGGGCTTCATCCACCCCGAAAGCTTCAACCAGGCCAACACTGACAACCATGtTGAACCCGTAGATGCCCGTCCAATTCCAGATAGGGGTCTGCCTACGAGACCCgAGATTCCAAAGGTTCGGCTGGACATTGAAGAAAGGCACAACGCTGGTTATGATGTTCGTGACAAGAGACTGATGTTCCTTGCAGAAGACATGGGCTCTAATAAGGGGGCGATCATTGGGCTGATGGTGGGTGGAGTTGTCATCGCTACCGTGATCGTAATCACTCTTGTTATGCTCAGGAAGAAACAGTACACTTCCATTCATCATGGAGTTATTGAGgtGGATGCAGCAGTGACCCCCGAGGAGCGTCATCTCACCAAGATGCAGCAGAACGGCTACGAGAACCCCACCTACAAGTTCTTCGAGCAGATGCAGAACTAAAGAACCACTTCAGACCCCACGCTCCACATCACCCCCAACCATCACCACCGTCACCCCACTGCATCAGGACAGAGAATGCAGACAGGTCCCTCATACACGCAGCTCTGTCACCACGGAGATGAGAGTGGCTTCCATCACCTGACCATTTCATCCAATCGAACGAGCGCTCACTCAGTTTGCACAGAAGCGTGATGTGTCATTGCCGCCCATCCAGCCATCTGTCAGTACGATGGTCCATCTGCGCTCTCCCATGCCTGTCCATCACAGCACTGTGCGGTGAATGAGCCGTTCTCTTTGCCCGTGCTTTCCTTCTTACCCATGATCCTCTAAACCATCTAtagtttgtttttgggtttttttttcttctctccgctctctctctctctctctctctcttggccGTGTTTGTTCCCCTCCAGAACTTTTATTAAGCGCTTACATCTCCTCCTCTTTTGTTTGCACGTTTCCTTCCTCCTTCTCCCTCCTTCCTTTTTCCTGGGCACTCAGATGATGCGGTGCTGTGTTTGGCTACATGAGGCTCCAACCGCAAACAACCAGATGCCGAATAACGTACTCATTGTTAAACTTTCCATTcagggttgttgtttttttttttctggaaaaaaagcaaaaaaatatatattaaaaaaaatccatacattaaaaaaaaatgtaaaaacaaacaaaaaacatttacagagataagaaatatgaatgtttgtttttattttgtgtgtaatatgtatTGAATTAAGGCAGAAACTAGCTGTATCTATATAGTGCATGGCAATTTTAACAGAGAGATGGTTTCTGGATCCAGTTGCGCAGACTTTGACCTCTCTCTTATGTAGAGATTTTAGCTGgattgtacattttattgtcTTCTTGtgatcacattttaaataagtgagaaaaaaaaaatctgcttggCTACATCGTCACAGGGACATGCTTTAATCGaagtgtgctttttatttcttttggacCATGCCACGCACACTTAAATAGTTGCATGGGGCTGGAAAAAGATGTATGTATTGTATTATGAAGTGTAATATTAGCCCACGTTTTGGTTCGTTAacgttttaacattttcttttcgGGAAGGGTCTAGACCCTTTTTGCCTCATGAAGTTTTATTCCATGTCGGGATTTGGTATGGGGCCGGGATTAGGGAAGGGAGGTATGGAGCGGTGGTGGGATTTTGCTTCAGAAATGGCCACCATTTTTGGATTGTGTGATTTTTGTCCCACTTTCCCCTCTTTGTATCCCCAGTGTCTGTGATATTCACGAACACATTTTGGGACAGAAACACCTCACCTTCTCCCCCTCTTTTATTGTTTCACTGAAGTATCTCATAGCACCTTACAGGCCAGAGCAGGTAAGAAGGAACGGGTGGatgagaaatattaaatgtaacgCAGTCTTTTGAAGTGACCTCTCcagagttattttaaaagcgCCGCAACGTTGAAGGAAATTGTGAATTGTTGTATAATACATTGTATGAGACACACAGCCATTAAACGAGTCAAACATTGTGCAGTTATGTCACAGTGCACACTGCTCATTACGTTCCTGTATAGAATTACCTTAGCTCAAAAATCTGGTGTTGTGCTGATTAGTGGATGCTCTGAGGTGAGTGTCTGTGGTCAGTAGGGAACAAAGAAAGCTCTTTCTGTGACTTTTTCCTTCAGTATCTATTCAAACCATTGGCTTAGAACGGGAAAAGCTTTCTACAACACTGTAACCCATGAATAAAGTTTTGAATGTACATACAAA
>XM_043248530.1
CAGTCGCGCATTCTCACAAAGCACAACCGAGCACAGACGATAGGGGAACACGGAGCAGAAGATCGACACAGAAAACCCTGATCCGCTCGGGACGTTTATCCATCAGGACGTGCTGCGTTTGGGAACACGGCCATGGGTATGGACCGTACGGTATTCCTGCTGCTAATGCTGACGACTCTGTCGCTCGCCATCGAGGTGCCATCGGATGACTCGGTGGGCTTGTTGGCGGAGCCCCAGGTGGCCATGTTTTGTGGGAAACTCAACATGCATATCAACATCCAGAGTGGCAAGTGGGAGCCGGATCCAACTGGCACCAAAGGCTGCATCGGCACCAAAGAGGGCATCCTTCAGTACTGCCAAGAGGTATACCCAGACCTCCAGATCACTAACGTGGTGGAGGCTAACCAGCCCGTCAGCATCCAGAACTGGTGCAAAATGGGTCGTCACCAGTGCCGCAGTCACACGCGCATTGTGGTCCCCTACCGCTGCCTGGTTGGGGAGTTTGTCAGCGATGCCCTCCTCGTCCCAGATAAATGCAAGTTCCTGCACCAAGAGCGAATGGACATGTGCGAGAGTCATCTGCACTGGCACACAGTGGCCaaagagTCCTGCGGCGATCGTTCCATGAATCTCCATGACTACGGCATGCTGCTGCCGTGCGGCATCGACCGTTTCCGTGGTGTGGAGTTTGTGTGCTGCCCTATGGAGGAGCAGAAGGAGTTAGACAGcgaggagcaggaggaggccAACTCAGATGTGTGGTGGGGCGGCGCAGAGGCCGAGTATACTGACGGCAGCATACTGAAAGAACAGGCCCCGACTAAACCTGAGCCTGCTGTGACTGAGGATGATGAGGATATCAAcaatgaggaagaggaagtctGGGATAATGATGAAGATGGTGATGGTGAAGATGATGACGACGAAGAAGATGACGATGAAGACACTACTGATGAACAAGACACCAGTGAGCAGACCTCCAACGTTGCCATGACAACCACCACCACTACCACAACAGAGTCTATAGAGGAGGTTGTGCGAGTGCCGACCGTGGCTCCGAGCCCTGCTGATGCTGTGGATCGTTACCTGGAAGCTCCAGGAGACGTGAATGAGCACACCCGCTTCCAAAAGGCAAAGGAGAGCCTGGAGGCCAAACACAGAGATAAAATGTCAGAGGTGATGAGAGAATGGGAGGAGGCAGAGAGACAGGCGAAGAACCTCCCCCGTGCTGATAAGAAGACCATAATTCAGCGCTTCCAGGAGAAGGTGGAGGCGTTGGAGAAGGAAGCGGCCGGGGAGAGGCAGCAGCTGGTAGAAACCCACATGGCACGCGTGGAAGCTCTGCTGAACGACCGCCGCCGCCAGGCTCTGGAAAGCTACCTTAGCGCCCTGCAATCTGACCAGCCTCGGCCTCGGCAGGTCCTCAATCTGTTGAAGAAGTACATACGAGCGGAGCAGAAGGACAGGCAGCACACGCTCAAACACTTTGAGCACGTGCGAGAGGTGGATCCCAAGAAGGCTTCTCAGATTCGGCCTTTTGTAATGACCCACCTGCGCGTGATTGAAGAACGCATGAACCAATCTTTGGGGTATCTCTACAAGGTGCCGCAGGTGGCTAATGAAATCCAGGACCAAGTGGcATTGCTGATTCAACATGACCAGGCTGAAGTTACCCAACAGCTGTCGTCTCTCCAGAGTAAGATGAGGGTGAGCTACGGGAACGACGCTCTGATGCCCGACCTGCCGGACAGCACCACCCCGCTGGACACCTTGCCACCGGAGCAGGACGGCCTGGGCTTCATCCACCCCGAAAGCTTCAACCAGGCCAACACTGACAACCATGtTGAACCCGTAGATGCCCGTCCAATTCCAGATAGGGGTCTGCCTACGAGACCCgAGATTCCAAAGGTTCGGCTGGACATTGAAGAAAGGCACAACGCTGGTTATGATGTTCGTGACAAGAGACTGATGTTCCTTGCAGAAGACATGGGCTCTAATAAGGGGGCGATCATTGGGCTGATGGTGGGTGGAGTTGTCATCGCTACCGTGATCGTAATCACTCTTGTTATGCTCAGGAAGAAACAGTACACTTCCATTCATCATGGAGTTATTGAGgtGGATGCAGCAGTGACCCCCGAGGAGCGTCATCTCACCAAGATGCAGCAGAACGGCTACGAGAACCCCACCTACAAGTTCTTCGAGCAGATGCAGAACTAAAGAACCACTTCAGACCCCACGCTCCACATCACCCCCAACCATCACCACCGTCACCCCACTGCATCAGGACAGAGAATGCAGACAGGTCCCTCATACACGCAGCTCTGTCACCACGGAGATGAGAGTGGCTTCCATCACCTGACCATTTCATCCAATCGAACGAGCGCTCACTCAGTTTGCACAGAAGCGTGATGTGTCATTGCCGCCCATCCAGCCATCTGTCAGTACGATGGTCCATCTGCGCTCTCCCATGCCTGTCCATCACAGCACTGTGCGGTGAATGAGCCGTTCTCTTTGCCCGTGCTTTCCTTCTTACCCATGATCCTCTAAACCATCTAtagtttgtttttgggtttttttttcttctctccgctctctctctctctctctctctcttggccGTGTTTGTTCCCCTCCAGAACTTTTATTAAGCGCTTACATCTCCTCCTCTTTTGTTTGCACGTTTCCTTCCTCCTTCTCCCTCCTTCCTTTTTCCTGGGCACTCAGATGATGCGGTGCTGTGTTTGGCTACATGAGGCTCCAACCGCAAACAACCAGATGCCGAATAACGTACTCATTGTTAAACTTTCCATTcagggttgttgtttttttttttctggaaaaaaagcaaaaaaatatatattaaaaaaaatccatacattaaaaaaaaatgtaaaaacaaacaaaaaacatttacagagataagaaatatgaatgtttgtttttattttgtgtgtaatatgtatTGAATTAAGGCAGAAACTAGCTGTATCTATATAGTGCATGGCAATTTTAACAGAGAGATGGTTTCTGGATCCAGTTGCGCAGACTTTGACCTCTCTCTTATGTAGAGATTTTAGCTGgattgtacattttattgtcTTCTTGtgatcacattttaaataagtgagaaaaaaaaaatctgcttggCTACATCGTCACAGGGACATGCTTTAATCGaagtgtgctttttatttcttttggacCATGCCACGCACACTTAAATAGTTGCATGGGGCTGGAAAAAGATGTATGTATTGTATTATGAAGTGTAATATTAGCCCACGTTTTGGTTCGTTAacgttttaacattttcttttcgGGAAGGGTCTAGACCCTTTTTGCCTCATGAAGTTTTATTCCATGTCGGGATTTGGTATGGGGCCGGGATTAGGGAAGGGAGGTATGGAGCGGTGGTGGGATTTTGCTTCAGAAATGGCCACCATTTTTGGATTGTGTGATTTTTGTCCCACTTTCCCCTCTTTGTATCCCCAGTGTCTGTGATATTCACGAACACATTTTGGGACAGAAACACCTCACCTTCTCCCCCTCTTTTATTGTTTCACTGAAGTATCTCATAGCACCTTACAGGCCAGAGCAGGTAAGAAGGAACGGGTGGatgagaaatattaaatgtaacgCAGTCTTTTGAAGTGACCTCTCcagagttattttaaaagcgCCGCAACGTTGAAGGAAATTGTGAATTGTTGTATAATACATTGTATGAGACACACAGCCATTAAACGAGTCAAACATTGTGCAGTTATGTCACAGTGCACACTGCTCATTACGTTCCTGTATAGAATTACCTTAGCTCAAAAATCTGGTGTTGTGCTGATTAGTGGATGCTCTGAGGTGAGTGTCTGTGGTCAGTAGGGAACAAAGAAAGCTCTTTCTGTGACTTTTTCCTTCAGTATCTATTCAAACCATTGGCTTAGAACGGGAAAAGCTTTCTACAACACTGTAACCCATGAATAAAGTTTTGAATGTACATACAAA

Function

symbol description
appb Predicted to enable heparin binding activity; serine-type endopeptidase inhibitor activity; and transition metal ion binding activity. Acts upstream of or within several processes, including convergent extension; nervous system development; and regulation of Notch signaling pathway. Predicted to be located in Golgi-associated vesicle and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including axial vasculature; axis; nervous system; pronephric duct; and spinal cord neural rod. Human ortholog(s) of this gene implicated in APP-related cerebral amyloid angiopathy; Alzheimer's disease; Alzheimer's disease 1; cognitive disorder; and visual epilepsy. Orthologous to human APP (amyloid beta precursor protein).

NR:

description
unnamed protein product

GO:

id name namespace
GO:0007409 axonogenesis biological_process
GO:0007417 central nervous system development biological_process
GO:0060026 convergent extension biological_process
GO:0001944 vasculature development biological_process
GO:0016021 integral component of membrane cellular_component
GO:0005515 protein binding molecular_function
GO:0008201 heparin binding molecular_function
GO:0046914 transition metal ion binding molecular_function
GO:0004867 serine-type endopeptidase inhibitor activity molecular_function

KEGG:

id description
K04520 APP; amyloid beta A4 protein

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043248528.1 True 4176 mRNA 0.50 17 17299245 17315818
XM_043248530.1 False 3999 mRNA 0.49 16 17299245 17315815

Neighbor

gene id symbol gene type direction distance location
si:ch211-160b11.4 NA coding downstream 100854 17196411 ~ 17198391 (-)
mettl21cb zgc:172067,LOC107673723,LOC107748129,LOC107597488 coding downstream 107103 17188746 ~ 17192142 (-)
dcun1d2a dcun1d2a,LOC107597495,LOC107673709,LOC108426072,LOC103045446,LOC107756765 coding downstream 123531 17170549 ~ 17175714 (-)
cdc16 cdc16,LOC107673708,LOC107597489,LOC107748135,LOC107595809,LOC107756764,LOC107695467 coding downstream 128831 17161943 ~ 17170414 (-)
upf3a upf3a,LOC107673688,LOC107756766,LOC107597564,LOC107748176,LOC107695475 coding downstream 137708 17151898 ~ 17161537 (-)
zp2l1 NA coding upstream 243710 17559528 ~ 17574374 (-)
dnajc28 dnajc28,LOC107748188,LOC107673653,LOC107597584,LOC107756751,LOC107656783,LOC107569146 coding upstream 334157 17649975 ~ 17652121 (-)
ralba ralba,ralb,LOC107746258,LOC107597482,LOC107596059 coding upstream 712536 18028354 ~ 18038668 (-)
hspbap1 LOC107722869,LOC107661136,LOC107660643 coding upstream 881308 18197126 ~ 18205461 (-)
adcy5 adcy5,LOC107555914,LOC107661140,LOC107660638,LOC107596066,LOC107714401 coding upstream 1111254 18427072 ~ 18492873 (-)
G71117 NA non-coding downstream 2095 17212876 ~ 17297150 (-)
G71035 NA non-coding downstream 379931 16917224 ~ 16919314 (-)
G70981 nxpe3,LOC107597504,LOC107748146,LOC107673677,LOC107695470,LOC107756776,LOC107595812 non-coding downstream 431723 16866492 ~ 16867522 (-)
G71006 NA non-coding downstream 432823 16866178 ~ 16866422 (-)
G71005 NA non-coding downstream 433656 16865278 ~ 16865589 (-)
G71131 NA non-coding upstream 23302 17339120 ~ 17339530 (-)
G71134 NA non-coding upstream 24727 17340545 ~ 17340915 (-)
LOC122352115 NA non-coding upstream 27898 17343716 ~ 17351712 (-)
G71149 NA non-coding upstream 276146 17591964 ~ 17592183 (-)
G71152 NA non-coding upstream 277895 17593713 ~ 17593933 (-)
G71118 erbb4,LOC107660610,LOC107721020,LOC107741926,LOC103360983,LOC106519748,LOC103461563 other downstream 43754 17235872 ~ 17255491 (-)
cd247l cd247l,LOC107595825,LOC107673686,LOC107756738,LOC107597501,LOC107748195,LOC107695491 other downstream 409698 16886753 ~ 16889547 (-)
G70986 pou2f1b,LOC107748141 other downstream 475470 16817140 ~ 16823775 (-)
dcaf6 LOC107673675,LOC107695452,LOC107748145,LOC107595867 other downstream 553023 16720804 ~ 16746222 (-)
G70663 plcl1,LOC107731752,LOC107569711,LOC107690606,LOC107659890,LOC107595846,LOC107719808 other downstream 1527381 15771421 ~ 15771864 (-)
ncam2 ncam2,LOC107756756,LOC108426076,LOC107595857,LOC107673712,LOC107748174 other upstream 48369 17364187 ~ 17521560 (-)
sema5ba sema5ba,sema5b,LOC107597557,LOC107660660,LOC107596063 other upstream 935418 18251236 ~ 18366267 (-)
LOC122352185 NA other upstream 1253937 18569755 ~ 18569882 (-)
ankar ankar,LOC107728908,LOC107660654 other upstream 2404124 19719942 ~ 19731794 (-)
glsb glsb,gls,LOC107660591,LOC107728921,LOC107714384,LOC107657529,LOC107602138,LOC106531437 other upstream 2480434 19796252 ~ 19829475 (-)

Expression


Co-expression Network