bmpr2b (bmpr2,bmpr2b,LOC107668372,LOC107593012)


Basic Information

Item Value
gene id bmpr2b
gene name bmpr2,bmpr2b,LOC107668372,LOC107593012
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056707.1
NCBI id CM032076.1
chromosome length 26426558
location 8257943 ~ 8316394 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043249067.1
agggaggaggggTGAGGAGGAGGTCTGGCTGCCCTTCATCTGTCTGCTCTAGGCGGAGCTGAAGTTACCGAGAGCGGCTGCGGGAGCTCGACGCGATCCGCGGGGCGATAATCATCCGGACCGGGAGAAATGCGCTGATTTACCCGAGCAGGCCCTGACCGGAGATCAGTTCCCCGACCATCATCGAGCCAGACTCGCTGCGCTGTTTGTTACAGGCCTCTGTCGCTTTGGATCGGACTCGATGTCGCTCCTGTTCGGCCGCTTGAAGCGACCGCTGGGCTCGACGCCTCCTGCCGTAGATTTGCCTCGTTTCACAGACGCGATTCTGGCCTCGACGAAGGAATAAAAGCGGGCGAAGCAGGGAAACGTCGGACATGTCGTCAGCTCGCGAAGCCAAACAACGACTGAAGCGGACTGAAACCAAGAAACCTGACCCACATTAAGATACCGCTCGAGCGTCTGGACCGGAACCAAATACATCGAAACTAAATCTTGTTTATAAACACCGATAAGCGCCGAGACGCGATCGCAGCGGGTTTCGAGAGCTCTCCTAAAAGGGCTGAAGACGCGGGCACTGCGCGAAGTCTAATCGCTCAAACTCCAACCCAGCATGGAGAAAATGCGTTTGTAATCTATTTGCCGAAGCGCACGCTGACCTAAAGGCGTCTGAAATCATGCATTGCCTCCAAACGCCCGTCTGCACGTCTAATTTCGGACTATTCCCTCCGAGCACATGAGTTTGAACTTCGGTCGATAGAGAAGAGGGGAAGAAAAGAGAATCTGctggaacttttttttatttggagcCGAACCCGTCCAGAAGCACCAGGACCGTCACCAGGATGAGCGCGCGGATCCTGAACCGAACATTAGTGCTGTCACTGGGGCTGTGCACGTTGCTTCTGCTCAGTGCCGTGGCTGCTGCTCAGAGTGAGGAGAGAGAGCGGGAGTGTGCTTTTAATGACCAGCACCAGCAGGGGGATGAGCAGAGTGTGGCTGCTGACTGGCACATCACCAGAGAAAATAACACCATCCTGTGCAGCAAGAGCAGCCGCTGCTACGGCCTGTGGGAGAAAACACATGACGGAGAGATCCGCCTGGTCAAACAAGGCTGTTGGACGTACATTGGCGACCAGCAGGACTGCCATGACGACCGTTGCGTGGTTACTACAACGCCGTCGCAGATCCAGAACGGCACCTACAGATTCTGCTGCTGCAGCACTAACATGTGCAACGTCAACTTTACAGAAAACTGGGTGCCCAGCCCTACCAGCACCACCCAAGAGCAGCAGCCTCTACACAGGGACGAGGCCATCTTCATCGCCCTGGCATCTGTCTCTATAGTAGCGGTCTTGATTGTGGCGCTGTTCTTCGGCTATCGCATGATGATGGGCGAGTGTAAACAGGGTCTGCACAATATGGACATGATAGAGGCCGCCCCGTCAGAACCATCTCTGGATTTAGATAGTTTAAAGCTCCTGGAATTGATCGGTCGAGGACGCTACGGTTCTGTCTACAAAGGATCACTGGATGAACGCCCAGTCGCCGTAAAGGTTTTTACCTATGCCAACCGGCAGAACTTCGTGAATGAGCGCTCCATCTACCGAGTCCCTCTTCTGGAGCACGAGAACATCGCTCGTTTTATTGTTGGCGATGAGCGTCTCACGACAGATGGACGGATGGAGTACCTGCTGGTTATGGAGTACTACCCACATGGCTCTCTGTGTCGTTACCTGAGTCTGCACACGCTGGACTGGGTGAGCTGCTGTCGTCTGGCACATTCGGTGACGAGAGGACTGGCCTACCTTCACACCGAGCTGCTCAGAGGAGATTTGTATAAACCTGCCATTTCACACCGGGATTTAAACAGCCGTAACGTTCTGGTGAAGAACGATGGCACGTGTGTGATCAGTGACTTTGGCCTGTCCATGAAGCTGACGGGAAATCGTCTCGTACGGCCTGGTGAAGAGGAAAACGCAGCCATCAGTGAGGTGGGCACGATCCGCTACATGGCGCCAGAAGTGCTGGAGGGAGCGGTGAACCTCAGGGACTGCGAGTCGGCTTTGAAACAGGTGGACATGTACGCCATCGGCCTCATCTACTGGGAGACCTTCATGAGATGCACTGACCTTTTTCCAGgggaGGCAGTGCCAGATTACCAGATGGCCTTCCAGGCCGAGGCAGGGAACCACCCCTCCTTTGAGGACATGCAGGTGCTGGTGtccagagagaaacagagaccCAAGTTCCCAGAAGCCTGGAAGGAGAACAGCCTGGCTGTGCGCTCTCTGAAGGAGACTATGGAGGATTGCTGGGATCAGGATGCAGAGGCTCGTCTGACAGCGCAGTGTGCAGAAGAGCGTATGGCAGAACTGCTGCTGATCTGGGAAAGAAACAAACCCGTCAGCCCCACTATCAATCCCATGAGCACAGCGCTGCAGAACGAGAGGAATCTCACCCACAGTCGCAGGGCTCCAAAGATGGGCTCTTATCCAGATTACTCTTCATCCTCTTACATCGAGGATCATGAGGGCATGGTGAAGAATCTCCCAGGCGACGTCTCCACATCTGGCACGTCCTCTGTGGGCGTGAGCGGCATCAGCGGAGGCGTGCCGGTGACGGGAGAGAAGAACAGAAACTCCATCAACTACGAGAGACAGCAGGCTCAGGCCCAAGCTCGGCTGCCCAGTCCAGAGACCAGCGGCACGAGTCTGTCCGCCACAACCACTACAACAGGCCTCACACCCAGCACCATCATGACCACCATCTCTGAGTCGGGCCACTCAGAGGAGGCCGGCGCCGGGGGAAGCGTACCGGTGTGCCTTCAGCTCACAGAAGAGGACCTGGAGACCACCAAACTGGACCCCAAAGAGGTGGACAAGAACCTGAAAGAAAGCTCTGATGAAAACCTAATGGAGCATTCGCAGAAGCAGTTCAGCGCTCCTGACCCGCTCAGCTCAGGCAGCTCTAGCCTCTTGTACCCGCTGATCAAACTCGCCGCAGAAGTGACCGGAGGATCAGGAACCGGCAGCCAGGCCGATTTCGGGGTGGGAGGCAGTGGAATGGGCGACACTCCTACAGCCATGTTCCCTCTTCCCAAACAGCAGAATCTCCCCAAGCGGCCCACCAGCTTGCCCCTCAACACCAAAAATTCTGGCAGGGAGTCTTCGACGTCACGGTTGAAGTTTGGCAAGCACAAGTCCAACCTGAAGCAGGTGGAGACGGGCGTAGCCAAGATGAACACTGTAGTGAGCGTCGAGCCGCACTTGGTCACCGTTACTAACAACGGGCCCAGTGTCCGTAGCGGCGTTGGAGTGGTGGTTGTTAATGGATATGGTGGAGGCAGTGGCGCCGGCTCCTCTGATGCGTTTGGGAACACCAACCCAGCCGGGCCGCAGGGTGACGGAGGCGCACCTCTGCTCCAGAGCCAGCTAAGCGGAGAAGACAGCCGCCTCAACATCAACATCAACTCCAGTCCTGATGAACACGAGCCTCTGTTGAGGAGAGAGCAGCCAGCGGCGCGCGACCACTCTGGACGCACCAACtccaataacaacaacagcaacatcCACACAACCGCCACCATTCGCACCTTAGCTCCTGTAGATGCCCAGATGGAGACACTTACCTGCCCTCCAGGGGCGCTGGATGGAAAGGATGATTCAGAGGTTCCTCTGAGACAGCATAAGCCCAGGAGACCTGAGAGGCCCAACTCACTGGACCTGTCAACAACTTCACAGGATTCTTCTCTTCTGGATGAGGTCGTGTCACAAGAGGAAAAAGCCGGATCGGCCGAGAAGATTAAGAAGCGCGTGAAGACACCTTATTCGTTGAAAAGGTGGCGTCCTTCTACGTGGGTCGTCTCTACAGAAACGCTGGACGGAGAGGTGAATAACAATGGGCACAGCCAGCAGACGGGGACGGCGGCGACCGGGGGCGCTCACCCAGGTTCTGGCCATTCGAAATCCAGCATCGCTGTGTTCCTGGTCAGCGGTGGAACGGCCACCGCCACTCTGACCTCCGACCCGCCAGATATGACCTGCCTGTGAACTCCGAGGACGAGCCCAGATCAGACTTTGAACGCAGGAGAGGGGTTCGTCGATGCTATCGTGCTCCAAAAACTGATCCAGCTGATGAccgaaaaagaaatatatatatatatatatatatatatatatatatatatactgaaaaaaCGTTTTTGGAAAGCAGACTCTTGAAGGGACGTAATTTGGCAAGCACTTAATTTTGTCGGACTTATCCAACTTGTTTTGAAGAAATCGCTTTAAACCGAACCCAGCTATGCAGCAACATTGGCATAAAATGCTTCCATTTGTTTttgtcgttttgtttttttttaattgtttcaatTGTTGTTCTTTCATTcgttgcacttttttttttttgtaagcaaTCTTAATCGCAAATCCTCCATGACCATGTTCAAGACTGGTCTTAAAAGTGAAAAACGTAAATGACAATGTGTTGATTTAACAATCATAGTAAATTAGACGAAATTCAAATCTTGTCCATCTAAAGAAAAGATAAATCAGTGGTCTTTAAGACGGGGTTGACTGCAACTCTAATACCGTTTAACCCACAGtacatatgttttatatttgttgtacGTATCTGTGTactcagttttttttgtataatattttaaaatgtgcaatagACTTTAGCTTTGAGGTGCTCCATAAGACAATTTCATTTTGCTATGTGTTTTACGCCGCGTTTGTTTATTTCTCGTCTTGAAGCGCTGCACTTAGCAGTGGCAGTCCTGTGTCCATTCGGCCGCCCCGACTGCAAACATCGTACAAATGACAATCCAACACCTTTTCACCAATCCCATCACTCTCGAAAAGGGAAGTAATCAGAAAGTATTGGGGTGTTTGCTTTAATTGCCAGAAGTTTATAACGGATGACTTCTCCCGAGCTTCAACGAGGacagtcgtttttttttttctgttacacTACAAGTCAGGCGTCAACCTGGATTGTTTGCTGGAAATCGTGCTTTCTGAAGACACTGAATGATCAAGTCCCTCTCTGCACACGCTCAGTGCAGTTTTACCTCTGTGAGAgtgtatgtaaatgtgtatgtatggGTTTACTTCTGCTTTACCGAGCTCCTCGGATCACAGCTGAAAAGCGTTCCACGTCCCATCTCTGCCAGGACGGTGGATGTCACTCCGTGTGCTTCagaaagcaaacacacacacacacacacacatacgccgTGAAAAcgatatatacagtatgtacagaCTGAAGCTCACAGCTACTTTAGTTCAGTTTTAGCCTCTGTTAAAATAAGCTGACATGATAGTGTATAATAAGAAATCATGACTTTATCCATTTTAGCTGTTTCagaagttatttttttcctctttatttttttaaatgcttaatttaTGTAGTACCCAGGGCCATTTTTGCACTCTGGGTTTATTATTCTCATGAAATCAAATCGGCAAGTTGTTTATAATCATGTAAATGTATCTTATCTCAGTGACACTTTTGATCGAATACATCAGAAATGCATGTAGTTTACCCCATCAAATTTGTACCATCGAGGAAGGAttggcacttttttttaaagtgccaCTGGAAACGTTCATAGTCGCGTTTAAGTGCCGTATCCTCGTTTTGAAGTCGTCTACACTTTGAGAGCAGTTGATGTTTTTACCAGCCGTAACCTGGGCCTCGTTTTTTTTATCCTACAACTGCTGCCTTTTGTGGAAAACTATGGACACGGGCCATCCAAATAATTACATAGTGATGAGGAAAATTCCCTCATATAGCAAGGCCCTGCTTTGCTGGAAATTGCAGGAAAAACGAAGATAGCGCACATTTGATCAGAGAGCACTTATTGTGCTCGTATGCGTTTTCCATAATGAGTGCTGGGATTAACCATGATTTGGCTCAAGCCTGCATTGACTTTGGACTCTGTCCATTCCAGAGCGGggaactttaaaaaaagtcatctgATTTTTCCCTTCCACTGGCTTTTTCTgttggaaaacaagacaatacgGTGCAGTTTAGTTTCTCACGCCCTCTTTTCTGAACCAATCGGCGCTTCAGTCTGACTTTGTATATGTTTGTAATATAGGCTAACCTCTGTGGTGTAAATATGTACGGTGCATTTGTATGCACACATGCAGACTCTTCATCTGTTGCTTTGGGACCAAGAACAACGCTAAATCACTGTGAGACTGACCTGAAGATAAACACAGTAACGTCAGACTGTTCTCAGCTAGATACGCCAGTGTGAATGCTGGAGAAGATTGTGAAACCAAACGAGGAATAATAGCCTAATGAAAGGCAAAACAAACCTCCAGTGCTAATTTGGCTGAAACGAGCAAACGTTTGTGATTTAGGCCAAAGCGTTGAAGCTGAAACGTTGAAGAAGCTGAGTCATTGGAAGTGTAGTTTTTTCAGGAGGACTGTCCATCTGCTACATGTTAATAATGCAAGATGTTTACACCAGAGCCTTTGTCCAGTTTTACAGCACACAGTTGAATACTGAATCATTTACAGATACTACATGCCTTGTTTATTCTTGAAGCAGGCCTTGAGAAGTCAGACTTTTTTAATTCAGTCAAGTTGCAGGAATGTTTTAACTAAACCATGCTGTACTCTTGAGTAAAACAATTGATCAGTTACTGTAACCTACATCGATTGGAACTcattacaaaaatgacaaatggctATCGATGTGTCCCCTACAACACGAACTTTTGAGTATCCGCTGTATTTTGGGGCGCGTATGAGCGAATGAATGAAGGGTCTGTGTTGACAAGCTgctgttttcctttttactttCGAGTTCATTTCGAAGCTGAAGTCTTCATTTGGCCCCCTGCGTAGATggatgttcaaaaaaaaaaagccactgaCATGTTTTCTATTACAGCTTGTAAAGTAAGCACTTtgagaaaaagaacaaatgatAACTCATGCTTTTAGTCtattcagaaaatgttttaaaatgccatttagaaaataaagctTGCTGTACAACCCTGCATTACTCAGTTGATTAAAGattatattaatgaaaa

Function

symbol description
bmpr2b Enables transforming growth factor beta-activated receptor activity. Acts upstream of or within BMP signaling pathway; embryonic organ morphogenesis; and vasculature development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including blood island; cardiovascular system; gonad; gut; and posterior pronephric duct. Human ortholog(s) of this gene implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease. Orthologous to human BMPR2 (bone morphogenetic protein receptor type 2).
bmpr2 Enables BMP binding activity; cadherin binding activity; and protein tyrosine kinase binding activity. Involved in several processes, including negative regulation of cell population proliferation; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and regulation of blood pressure. Acts upstream of or within positive regulation of SMAD protein signal transduction. Located in adherens junction; nucleoplasm; and plasma membrane. Is integral component of plasma membrane. Colocalizes with caveola. Implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease. Biomarker of asthma and pulmonary hypertension.

NR:

description
PREDICTED: bone morphogenetic protein receptor type-2

GO:

id name namespace
GO:0003146 heart jogging biological_process
GO:0048570 notochord morphogenesis biological_process
GO:0030509 BMP signaling pathway biological_process
GO:0006468 protein phosphorylation biological_process
GO:0001947 heart looping biological_process
GO:0016020 membrane cellular_component
GO:0005524 ATP binding molecular_function
GO:0005024 transforming growth factor beta-activated receptor activity molecular_function

KEGG:

id description
K04671 BMPR2; bone morphogenetic protein receptor type-2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043249067.1 True 7070 mRNA 0.49 13 8257943 8316394

Neighbor

gene id symbol gene type direction distance location
fam117bb fam117bb,fam117b,LOC107751499,LOC107752888,LOC107596526,LOC107668400,LOC107677778 coding downstream 224 8223701 ~ 8257719 (-)
carf carf,LOC107751498 coding downstream 35940 8212788 ~ 8222003 (-)
LOC122351474 LOC107600885,LOC107659206 coding downstream 48024 8204280 ~ 8209919 (-)
mpp4a mpp4a,LOC107738104,LOC107688761,LOC107752892,LOC107592993,LOC107668389 coding downstream 183497 8064653 ~ 8074446 (-)
tmem237a tmem237a,LOC107738107,LOC107668390,LOC107752911 coding downstream 194848 8056543 ~ 8063095 (-)
si:dkey-230p4.1 LOC107677784,LOC107596544,LOC107749895 coding upstream 569 8316963 ~ 8334613 (-)
hce2l1 si:ch211-167j6.5,LOC107749894,LOC107677777,LOC107596543,LOC107752908,LOC107668352,LOC107593026 coding upstream 20034 8336428 ~ 8338371 (-)
LOC122351780 LOC107677781,LOC107749905,LOC107596523,LOC107752886,LOC107668380,LOC107593025,LOC100003133 coding upstream 22600 8338994 ~ 8341460 (-)
trnak-uuu_106 NA coding upstream 24549 8340943 ~ 8341015 (-)
glb1l glb1l,LOC107596522,LOC107677787,LOC107752925,LOC107749887 coding upstream 32844 8349238 ~ 8355856 (-)
G68554 nrp2b,LOC107596550,LOC107716756,LOC107688751,LOC107593002,LOC107752901 non-coding downstream 436054 7820008 ~ 7821889 (-)
G68555 nrp2b,LOC107688766,LOC107688751,LOC107752901 non-coding downstream 439111 7815249 ~ 7818832 (-)
G68489 NA non-coding downstream 876435 7381290 ~ 7381508 (-)
G68473 NA non-coding downstream 916449 7327829 ~ 7341494 (-)
LOC122352164 NA non-coding downstream 1222582 6982678 ~ 7035361 (-)
LOC122352023 NA non-coding upstream 154469 8470863 ~ 8474578 (-)
G68822 NA non-coding upstream 445377 8761771 ~ 8835225 (-)
G68826 NA non-coding upstream 477467 8793861 ~ 8801749 (-)
G68830 NA non-coding upstream 485991 8802385 ~ 8805405 (-)
G68839 NA non-coding upstream 500126 8816520 ~ 8817618 (-)
als2a als2a,LOC107688763,LOC107596546,LOC107668398,LOC107752891,LOC107592992,LOC107738114 other downstream 163096 8076468 ~ 8094847 (-)
LOC122351623 raph1,LOC107592998,LOC107668371,LOC107752894,LOC107738113,LOC107688760,LOC107738116,LOC107596536 other downstream 233271 8014449 ~ 8024672 (-)
LOC122351350 cb064,LOC107688735,LOC107716767,LOC107676512,LOC108232354,LOC103042106,LOC105927538 other downstream 1103989 7070985 ~ 7153954 (-)
G68188 irs2b,LOC107715923,LOC107688717,LOC107559513,LOC107557930,LOC107721603,LOC107702923 other downstream 1996874 6246900 ~ 6261069 (-)
LOC122351979 NA other downstream 2158031 6099071 ~ 6099912 (-)
LOC122351483 LOC107663814,LOC107733620,LOC107555196,LOC107720141,LOC107600416,LOC107655476 other upstream 1591794 9908188 ~ 9910178 (-)
trim13 trim13,LOC107720128,LOC107555217,LOC107663864,LOC107706093,LOC107600394,LOC107655513 other upstream 2117113 10433507 ~ 10443619 (-)
fdx1 fdx1,LOC107663820,LOC107706088,LOC107720152,LOC107655504,LOC107600437,LOC107555213,LOC107655505 other upstream 2198878 10515272 ~ 10519457 (-)
mrasa LOC107551943,LOC107663912,LOC107733654,LOC107600440,LOC107738526 other upstream 2363764 10680158 ~ 10686627 (-)
LOC122351858 slc10a2,LOC107663831,LOC107567642,LOC107675341,LOC107738529 other upstream 3080272 11396666 ~ 11493120 (-)

Expression


Co-expression Network