LOC122343833 (LOC107749248,LOC107594233,LOC107703686)


Basic Information

Item Value
gene id LOC122343833
gene name LOC107749248,LOC107594233,LOC107703686
gene type misc
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056699.1
NCBI id CM032068.1
chromosome length 31761587
location 27240324 ~ 27255067 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043238077.1
CCGCTTCTTGCTTAATGCAGCCAGATGCCGAACACGATGCATGTGGAGATAGTGACGCTGACTGCCATCATTCTTGGCTTCCCTTTGCTTACGTTATGTGACCCACTGTATGTTCTGTCAGCTCCTAACTTGCTGAGGGTGGGTTCCTCAGAGAACGTGTTTGTGGAGGCTCAGGATTACTCTGGAGGAAACCTGAACGTGAGGATCATAGTAAAGAACCACCCAAAACGAGACAAGGAGATAATGTCTAAATCGGTGACACTGACTGCAGCCAACAATTTCCAGATCCTTGCAGATATAAAGAttcctgatgatcagaagttcTTCTCTGACGATCCTCTGGAGAAGCAGTATGTGTATCTACAAGCTCGGTTTCCAACTACCACTTTGGAGAAAGTGGTCATGGTCTCATTCCAGTCTggatatatatttgtacaaacAGACAAGCCCCTCTACACACCTTCTAGCACAGTTAAATACAGGATCTTCTCATTAACTCCTGATCAACATCCATTTGATGGAGTTTCCATCTCGGTCGATATCATGAATCCTCAAGGCATAACACTGGACAGAGATCAGTTCCAACCAAGGCGAGGCATCAGGACCGAAAACTTTGCTTTACCCGAACTTGCCAGCTCTGGGATTTGGAAGTTGATCGCaaagtacacaaacacaccgCAAAAGAACTTCACGACTGAATTTGAAGTCATGGAATACGtgCTGCCGAGCTTTGAAGTGACCTTAAATTCACGCAAACCGTTCTTCTATGTGAATGAGCGCTCTTTAACAGTAGACATATCAGCTAAATACCTGTTTGGTAATAAGGTGACAGGAACTGCATTTGTGGTGTTCGGCATTATAGACAATGAGAAGAAGATCAGCATCGCTGCCTCACTGCAAAAGGTTCAGATAAATGATGGAGAAGGAGAGGCAGAGCTGACTAGAAACATGATCAAGGAGAACTTCCCAGACATCCAGCAGCTAGTTGGGAAATCCCTTTACATTTCAGCCAGTGTTGTAACAGAAACTGgaagtGAAATGGTAGAAGCACACAAGAGAGGCATTCAGATTGTGACGTCTCCGTACACCATCCACTTCAAAAGAACACCACACTTCTTCAAACCTGGGATGTCCTTCGATGTCTcgGTCTATGTAACAAATCCTGACCAAACTCCTTCTAAAAATGTGGAAGTGGAGGTAAATCCTggaggggtcagaggtcaaacaaGAGCCAATGGCATCGCAAAAGTTACTGTCAACACTCCGGGAGGATCTTCCAAACTGGAGATCACTGCAAAGACCAAAGACCCACAATTAAGAAACGATCAGCAGGCAGTGAAGAAGATGATAGCTCAGGCCTACCAGCCCAAAGACGACTCCAAAAACTACCTGCACATCGGCATTGATGCTACAGAGCTTCAGATCGGTGATCAAATGAAAGTCAATTTAAATCTAGGAAACAGCCATGTTAAAAACCAGGATTTCACCTACATGATCTTAAGTAAAGGTCAGATCGTTCAAGTGGACAGGTTTAAGATGAAAGGACAAGCTCTTGTGAGTCTGTCTCTGCCTGTAACCAAAGTCATGGTGCCGTCCTTCCGGTTTGTGGCGTATTATCATGTGGGCTCGTCTGAGGTGGTGTCCGATTCAGTCTGGGTCAACATGAAGGACACGTGCATGGGAACGCTCAAAGTTGAGGTGAAGGACCCGACACAATATGGCCCAGGAGATCAGCTCAGCTTGAAAATCACTGGAGACCCTGGAGCTAGAGTCGGGCTGGTCGCTGTAGATAAGGGGGTCTATGTCCTTAATAACAAGAACAGAATCACTCAGACAAAGATCTGGGACGTCGTAGAGAAGCATGACACCGGCTGTACGGCAGGAGGAGGAAGGAACTGTATGGGGGTTTTCACCGATGCAGGTCTGATGTTTGCGTCCAGCACTGCAGGAGGAACCAACGTCAGAACAAATAAAGAGTGCCCCGTCCCATCAAAGAGAAAACGCAGAGCACAGAGCCTTTTGCAGGTCACCACTACACTGGCTGGTCAGTTCTCCGGCGAACAAAAGAAGTGCTGTGTGGATGGGCTGAAAGACGTTAAACTTGGGTACAGCTGTGAACGTCGAGCCTCATTCATCATGGACGGAGATGAATGTATTCAGGCCTTCCTGCGCTGCTGCAAGGAGTTGAAACGCCATACAGATGCCTTCGCAGAGAACGAGTTTCTTCTGGCCCGCAGTGAAGATGATGATTTTGATGAGGAACTAGGAGAAGTGATGGTGCGTACACAGTTTCCTGAAAGCTGGCTTTGGGAGGAGATTGATCTTCCTCCTTGCCCACCGAACCAAGTGTGTGCTGAAACATCCACCTTAAGAACTGGAATATTCCTGAAAGATTCCATCACAACCTGGCAGATCACAGCCATCAGCCTGTCCCAGAGCCTTGGAATGTGTGTGGCTGATCCTTATGAGATCATTGtcaagaaagatttttttatcgACTTGAAGGTGCCTTATGCAGCGGTGCGCAATGAACAACTGGAAATAAAGGCTATTCTTCACAATTACAGCAATCAGAAACAGAAAACAAACATTCGGTTTAAGACGTCGGAGGGTATTTGCAGCAGTgccagcaaaaaaaagaaaggcaggGTAACCGTTCCTGTTGGCTCCATGTCCTCCAGAGCCGTCCCTTTCATCATCATCCCCATGGATCTGAAAGAGCAGTGGATCGAAGTGGAAGCATACAGCTCGAATCGCAACGACGCTATTAGAAAGAAACTGAAGGTGGTGcCTGAAGGTGTGCTAACCGAAGTCCAAGAGAGAATTATAGAGATCAACCCATCCAAGCATCCAGGCAGCTCGCAGGTCGTGTCTATGAGGAGCGACATCCCACGCCGAAGGGCTCCAAACACACCTGCTAGCACAGTGATCACGGTGATAGGTGAAGAGATCACTCAGACAATCGAGCAGGCCATCAGTGGACATTTTATGGGTCAGCTCATTGTTCAGCCCTATGGATGTGGAGAGCAGAACATGATCCATGTGACTCTTCCTGTCATTGCCACTCATTACCTGGACAGCACAAAGCAGTGGGAGGCTGTTGGCATGGAGCGGCGTAATGAAGCCGTCAAGCACATTAACACAGGTTATAAGCTGGAGTTGACCTTCCGTAAAGCCGATGGGTCATACGGTGCCTGGTTACACGTGCCGAGTAGCACATGGCTGACGGCTTATGTGGCCAAAGTATTCGCGATGGCCAGTGATCTGATTGTCGTAGAGGAGCATGTGATCTGCAGCGCCCTCGACTGGCTGGccacaaaaaaacagctgtcaGACGGCACGTTTAAAGAACATGCGCCTGTGTATCACAGCGAGATGGTTGGTAACGTACGTGGAAAAGACGCAGATGCCTCTCTGACTGCATTCGTCCTGATCGCCATGCAGGAAGGAAGAAAGATCTGTGCTGGAGCTAATATTCAGAACAGTATAAAAAGAGCCACCGATTACCTGCTGCTGAGAGTTCACAGCCTGACCAGCACTTACGCTGTCACTATAACGTCTTATGCTTTGGCCCACGCTGGAAGACTCAATAAAGACATCTTGAAGAGTCATTCTACTAAAAGCAAAGATGGAATATTTTGGCAAGTTCCTGGCCAGCACCATCACTCTCTAGAAGCCACGGGTTACGCAGTGCTTGCCCTGGTGATGGCAAAGGATTTCGAGAGTGCTGGACTGGCGGTGCGTTGGCTGGGAAAGCAACAATCCCGTTATGGGGGTTACGGCACAACACAGGCAACGATCATGGTCTTCCAAGCCGTGGCTGAATACCGCATTCGGGTTAAGAAGGCAGACATTAATTTGGACCTGGAGATGGCTGTGCAAGAGAGAAAAGGGAAAACCAAAATTGCTTTGAGACAATCAAGCAAACAACGTACAGACAAGTTTGACATCACGAAGAGCTTCAATCTCACAGCTCGTGGGACGGGGGTGGCCACGCTCTCCgtcttttctgtcttttatgcTCTGCCCGAAGAGAAAGACTACGAATGTAATGCATTTGATCTCAGTGTGCAGATGGAGAAAGAGTCTGCAGTAACCTACGATAAAGCCTCTGATAGTTACCTGATCAAGATTGAATACATTTTCAAAGACAAGTTAAGAAGCTCAACCATGTCTATTTTGGACATCGGTCTGCTGACAGGGTTCAAAGTGGATGAACGGGATCTTTCGAAGTTATCCAGCGGTAGGGATAAGTACATTCAGAGCTTTGAGCTGAACAAGGAGCTATCAGAGCGAGGATCTCTTATCATCTACGTGGATAAGGTTTCTAATAAACAGAAGGAAAGGATTGTCTTCAGAATGCACAAGATCAGTGAAGTGGGAATGCTGCAGCCCGCCGGAGTCACTATGTATGAGTACAATGCCCCAGATAAGCGTTGTGTGAAGTTTTACCATCCCTATAAGAAAGATGGATCACTGAACAGACTCTGCCATGAAGAGCTGTGCCAGTGCGCTGAAGAGAACTGCAGTTTGCAAAAGAATGAACACATCGATGAGGAAAAACGTGAAGAAAAGGCCTGTGAACGTGAAGTGGAATACAtttataAAACCAGAGTGTTGGAAATGAGCTTGTCATTGCATGTGGACGTCTACAACATGACAGTTGAGGAAGTGCTGAAGGAAGgCTCTGATCCAGCTGTAGAAGGACAAGTGAGGTCGTTTTTGGCTCATCCTTTCTGTAGAGATTTTCTAAAATTTGAAAAAGGCAAGACGTATCTGATCATGGGCCAAACCAAAACCCTTCCAAGGATTGGCGGAAAGTTGAGGTACCATTTGGGTGAGGACACCTGGATTGAATACTGGCCAACAAATAAGGAGGGTCAGGATCCAAAACACAAGCTAAAATATATCGGCATGACCTCGCTTGTCAACATGTTCAGGCAAACTGGATGTGCCACTTAAAGATTTTTACCGATCCAACAGCGTTACAGTCAcaactttgcttttatttccagcaatttgtctgattttatttttaaagttccTGCTCAGTTCTCTTGTGAGacaatttttcaaataaaatttgcaaacataaa
>XR_006250838.1
TCCGCTTCTTGCTTAATGCAGCCAGATGCCGAACACGATGCATGTGGAGATAGTGACGCTGACTGCCATCATTCTTGGCTTCCCTTTGCTTACGTTATGTGACCCACTGTATGTTCTGTCAGCTCCTAACTTGCTGAGGGTGGGTTCCTCAGAGAACGTGTTTGTGGAGGCTCAGGATTACTCTGGAGGAAACCTGAACGTGAGGATCATAGTAAAGAACCACCCAAAACGAGACAAGGAGATAATGTCTAAATCGGTGACACTGACTGCAGCCAACAATTTCCAGATCCTTGCAGATATAAAGAttcctgatgatcagaagttcTTCTCTGACGATCCTCTGGAGAAGCAGTATGTGTATCTACAAGCTCGGTTTCCAACTACCACTTTGGAGAAAGTGGTCATGGTCTCATTCCAGTCTggatatatatttgtacaaacAGACAAGCCCCTCTACACACCTTCTAGCACAGTTAAATACAGGATCTTCTCATTAACTCCTGATCAACATCCATTTGATGGAGTTTCCATCTCGGTCGATATCATGAATCCTCAAGGCATAACACTGGACAGAGATCAGTTCCAACCAAGGCGAGGCATCAGGACCGAAAACTTTGCTTTACCCGAACTTGCCAGCTCTGGGATTTGGAAGTTGATCGCaaagtacacaaacacaccgCAAAAGAACTTCACGACTGAATTTGAAGTCATGGAATACGtgCTGCCGAGCTTTGAAGTGACCTTAAATTCACGCAAACCGTTCTTCTATGTGAATGAGCGCTCTTTAACAGTAGACATATCAGCTAAATACCTGTTTGGTAATAAGGTGACAGGAACTGCATTTGTGGTGTTCGGCATTATAGACAATGAGAAGAAGATCAGCATCGCTGCCTCACTGCAAAAGGTTCAGATAAATGATGGAGAAGGAGAGGCAGAGCTGACTAGAAACATGATCAAGGAGAACTTCCCAGACATCCAGCAGCTAGTTGGGAAATCCCTTTACATTTCAGCCAGTGTTGTAACAGAAACTGgaagtGAAATGGTAGAAGCACACAAGAGAGGCATTCAGATTGTGACGTCTCCGTACACCATCCACTTCAAAAGAACACCACACTTCTTCAAACCTGGGATGTCCTTCGATGTCTcgGTCTATGTAACAAATCCTGACCAAACTCCTTCTAAAAATGTGGAAGTGGAGGTAAATCCTggaggggtcagaggtcaaacaaGAGCCAATGGCATCGCAAAAGTTACTGTCAACACTCCGGGAGGATCTTCCAAACTGGAGATCACTGCAAAGACCAAAGACCCACAATTAAGAAACGATCAGCAGGCAGTGAAGAAGATGATAGCTCAGGCCTACCAGCCCAAAGACGACTCCAAAAACTACCTGCACATCGGCATTGATGCTACAGAGCTTCAGATCGGTGATCAAATGAAAGTCAATTTAAATCTAGGAAACAGCCATGTTAAAAACCAGGATTTCACCTACATGATCTTAAGTAAAGGTCAGATCGTTCAAGTGGACAGGTTTAAGATGAAAGGACAAGCTCTTGTGAGTCTGTCTCTGCCTGTAACCAAAGTCATGGTGCCGTCCTTCCGGTTTGTGGCGTATTATCATGTGGGCTCGTCTGAGGTGGTGTCCGATTCAGTCTGGGTCAACATGAAGGACACGTGCATGGGAACGCTCAAAGTTGAGGTGAAGGACCCGACACAATATGGCCCAGGAGATCAGCTCAGCTTGAAAATCACTGGAGACCCTGGAGCTAGAGTCGGGCTGGTCGCTGTAGATAAGGGGGTCTATGTCCTTAATAACAAGAACAGAATCACTCAGACAAAGATCTGGGACGTCGTAGAGAAGCATGACACCGGCTGTACGGCAGGAGGAGGAAGGAACTGTATGGGGGTTTTCACCGATGCAGGTCTGATGTTTGCGTCCAGCACTGCAGGAGGAACCAACGTCAGAACAAATAAAGAGTGCCCCGTCCCATCAAAGAGAAAACGCAGAGCACAGAGCCTTTTGCAGGTCACCACTACACTGGCTGGTCAGTTCTCCGGCGAACAAAAGAAGTGCTGTGTGGATGGGCTGAAAGACGTTAAACTTGGGTACAGCTGTGAACGTCGAGCCTCATTCATCATGGACGGAGATGAATGTATTCAGGCCTTCCTGCGCTGCTGCAAGGAGTTGAAACGCCATACAGATGCCTTCGCAGAGAACGAGTTTCTTCTGGCCCGCAGTGAAGATGATGATTTTGATGAGGAACTAGGAGAAGTGATGGTGCGTACACAGTTTCCTGAAAGCTGGCTTTGGGAGGAGATTGATCTTCCTCCTTGCCCACCGAACCAAGTGTGTGCTGAAACATCCACCTTAAGAACTGGAATATTCCTGAAAGATTCCATCACAACCTGGCAGATCACAGCCATCAGCCTGTCCCAGAGCCTTGGAATGTGTGTGGCTGATCCTTATGAGATCATTGtcaagaaagatttttttatcgACTTGAAGGTGCCTTATGCAGCGGTGCGCAATGAACAACTGGAAATAAAGGCTATTCTTCACAATTACAGCAATCAGAAACAGAAAACAAACATTCGGTTTAAGACGTCGGAGGGTATTTGCAGCAGTgccagcaaaaaaaagaaaggcaggGTAACCGTTCCTGTTGGCTCCATGTCCTCCAGAGCCGTCCCTTTCATCATCATCCCCATGGATCTGAAAGAGCAGTGGATCGAAGTGGAAGCATACAGCTCGAATCGCAACGACGCTATTAGAAAGAAACTGAAGGTGGTGcCTGAAGGTGTGCTAACCGAAGTCCAAGAGAGAATTATAGAGATCAACCCATCCAAGCATCCAGGCAGCTCGCAGGTCGTGTCTATGAGGAGCGACATCCCACGCCGAAGGGCTCCAAACACACCTGCTAGCACAGTGATCACGGTGATAGGTGAAGAGATCACTCAGACAATCGAGCAGGCCATCAGTGGACATTTTATGGGTCAGCTCATTGTTCAGCCCTATGGATGTGGAGAGCAGAACATGATCCATGTGACTCTTCCTGTCATTGCCACTCATTACCTGGACAGCACAAAGCAGTGGGAGGCTGTTGGCATGGAGCGGCGTAATGAAGCCGTCAAGCACATTAACACAGGTTATAAGCTGGAGTTGACCTTCCGTAAAGCCGATGGGTCATACGGTGCCTGGTTACACGTGCCGAGTAGCACATGGCTGACGGCTTATGTGGCCAAAGTATTCGCGATGGCCAGTGATCTGATTGTCGTAGAGGAGCATGTGATCTGCAGCGCCCTCGACTGGCTGGccacaaaaaaacagctgtcaGACGGCACGTTTAAAGAACATGCGCCTGTGTATCACAGCGAGATGGTTGGTAACGTACGTGGAAAAGACGCAGATGCCTCTCTGACTGCATTCGTCCTGATCGCCATGCAGGAAGGAAGAAAGATCTGTGCTGGAGCTAATATTCAGAACAGTATAAAAAGAGCCACCGATTACCTGCTGCTGAGAGTTCACAGCCTGACCAGCACTTACGCTGTCACTATAACGTCTTATGCTTTGGCCCACGCTGGAAGACTCAATAAAGACATCTTGAAGAGTCATTCTACTAAAAGCAAAGATGGAATATTTTGGCAAGTTCCTGGCCAGCACCATCACTCTCTAGAAGCCACGGGTTACGCAGTGCTTGCCCTGGTGATGGCAAAGGATTTCGAGAGTGCTGGACTGGCGGTGCGTTGGCTGGGAAAGCAACAATCCCGTTATGGGGGTTACGGCACAACACAGGCAACGATCATGGTCTTCCAAGCCGTGGCTGAATACCGCATTCGGGTTAAGAAGGCAGACATTAATTTGGACCTGGAGATGGCTGTGCAAGAGAGAAAAGGGAAAACCAAAATTGCTTTGAGACAATCAAGCAAACAACGTACAGACAAGTTTGACATCACGAAGAGCTTCAATCTCACAGCTCGTGGGACGGGGGTGGCCACGCTCTCCgtcttttctgtcttttatgcTCTGCCCGAAGAGAAAGACTACGAATGTAATGCATTTGATCTCAGTGTGCAGATGGAGAAAGAGTCTGCAGTAACCTACGATAAAGCCTCTGATAGTTACCTGATCAAGATTGAATACATTTTCAAAGACAAGTTAAGAAGCTCAACCATGTCTATTTTGGACATCGGTCTGCTGACAGGGTTCAAAGTGGATGAACGGGATCTTTCGAAGTTATCCAGCGGTAGGGATAAGTACATTCAGAGCTTTGAGCTGAACAAGGAGCTATCAGAGCGAGGATCTCTTATCATCTACGTGGATAAGGTTTCTAATAAACAGAAGGAAAGGATTGTCTTCAGAATGCACAAGATCAGTGAAGTGGGAATGCTGCAGCCCGCCGGAGTCACTATATAAGCGTTGTGTGAAGTTTTACCATCCCTATAAGAAAGATGGATCACTGAACAGACTCTGCCATGAAGAGCTGTGCCAGTGCGCTGAAGAGAACTGCAGTTTGCAAAAGAATGAACACATCGATGAGGAAAAACGTGAAGA

Function

NR:

description
PREDICTED: complement C3-like

GO: NA

KEGG:

id description
K03990 C3; complement component 3

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043238077.1 True 5096 mRNA 0.47 41 27240324 27255066
XR_006250838.1 False 4552 transcript 0.47 38 27241224 27255067

Neighbor

gene id symbol gene type direction distance location
c3a.6 c3a.6,LOC107703739,LOC107594231,LOC107749254 coding downstream 1591 27223905 ~ 27238733 (-)
c3a.4 c3a.4,LOC107749249,LOC107747139,LOC107703775,LOC107594303,LOC107572266 coding downstream 16563 27208559 ~ 27223761 (-)
LOC122344463 NA coding downstream 44263 27194089 ~ 27196061 (-)
LOC122344496 NA coding downstream 52595 27186219 ~ 27187729 (-)
LOC122344447 asf1bb,asf1b,LOC107747137,LOC107573603,LOC107703766,LOC107694608,LOC101069596 coding downstream 54422 27180727 ~ 27185902 (-)
dennd1c LOC107694614,LOC107594230,LOC107747169,LOC108258416,LOC107572265 coding upstream 25234 27280301 ~ 27289321 (-)
LOC122344156 LOC107578363,LOC107574523,LOC107576205 coding upstream 124931 27379998 ~ 27393878 (-)
LOC122344221 LOC107574524,LOC107578363,LOC107574523,LOC107576205 coding upstream 162886 27417953 ~ 27421722 (-)
LOC122349201 NA coding upstream 167887 27422954 ~ 27426147 (-)
LOC122344204 NA coding upstream 176663 27431730 ~ 27438279 (-)
G6949 NA non-coding downstream 148895 27064144 ~ 27091429 (-)
G6933 adgre9,LOC107747176,LOC107694597,LOC107752408,LOC107752624 non-coding downstream 227953 27012123 ~ 27012371 (-)
G6929 NA non-coding downstream 230772 27009156 ~ 27009552 (-)
G6927 NA non-coding downstream 232337 27007503 ~ 27007987 (-)
G6926 NA non-coding downstream 233181 27006647 ~ 27007143 (-)
G6981 NA non-coding upstream 42108 27297175 ~ 27297611 (-)
G6957 NA non-coding upstream 44359 27299426 ~ 27321856 (-)
G6982 NA non-coding upstream 46739 27301806 ~ 27302275 (-)
G6983 NA non-coding upstream 48033 27303100 ~ 27305694 (-)
G6956 NA non-coding upstream 57876 27312943 ~ 27314514 (-)
LOC122344379 NA other downstream 37696 27196238 ~ 27202628 (-)
LOC122349164 NA other downstream 247742 26984544 ~ 26992582 (-)
si:ch211-286b5.5 NA other downstream 320290 26917669 ~ 26920034 (-)
c1h19orf53 zgc:136864,c26h19orf53,LOC107598479,LOC107700848,LOC107747197,LOC105901798,LOC106531096 other downstream 437370 26801910 ~ 26802954 (-)
LOC122353745 slc9a3r2,LOC107729606 other downstream 716922 26454250 ~ 26523402 (-)
LOC122344630 LOC107578363,LOC107571875,LOC107575964,LOC107575480,LOC107571874,LOC107574523,LOC107576205 other upstream 120250 27375317 ~ 27385079 (-)
G7105 epn3,epn3b,LOC107707724,LOC107571871,LOC107703747,LOC107745640,LOC107574648,LOC108411852 other upstream 499715 27754782 ~ 27939452 (-)
LOC122349330 LOC107571875,LOC107574524,LOC107703776,LOC107573813,LOC107707718,LOC107732931,LOC107703675,LOC107703672 other upstream 636834 27891901 ~ 28076645 (-)
nxnl1 nxnl1,LOC107748002,LOC107713785,LOC107571423,LOC107659782,LOC107690637 other upstream 965832 28220899 ~ 28223247 (-)
G7475 NA other upstream 989061 28244128 ~ 28248523 (-)

Expression


Co-expression Network