ppp3r1b (PPP3R1,ppp3r1,ppp3r1a,LOC108441257,LOC107727894,LOC107699153,LOC106024317)


Basic Information

Item Value
gene id ppp3r1b
gene name PPP3R1,ppp3r1,ppp3r1a,LOC108441257,LOC107727894,LOC107699153,LOC106024317
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056699.1
NCBI id CM032068.1
chromosome length 31761587
location 25509574 ~ 25522370 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043239774.1
ataaggcgGAAATACCCGGATGTGCTGTTCTAGCGCCCCTTCCCCCTCCGCTCCGCCGAGCCTCCCTCCCTCCtttcctctcttttctctctccaccACCGACTCAACCCACTGCCTCTTCCCCCTCCGCTGCGGACCCGACGTTACCGAAGCCACTGCAGCGAATCCGTCATCCGTCGACCGAAAAGCCCGAGGAGAAGAAAATCCCCGCGACTTCCTCGCGCAGAAAAAAGCAACCGTCGGCGACCCCTTCAGTTCCGCGAGACTCCGCGCAAGGCGAAGACGAGCCCGGCGACAGGATGGGAAATGAGGCGAGTTATCCCTTGGAGATGTGCTCACACTTTGACGCTGATGAGATTAAAAGACTAGGGAAGCGGTTTAAGAAACTCGACCTGGATAACTCGGGTTCTCTCAGCGTGGAGGAGTTTATGTCTCTACCCGAGTTGCAGCAGAATCCGCTGGTGCAGCGAGTCATCGATATATTCGACACAGACGGAAACGGAGAAGTGGACTTTAAAGAGTTCATTGAAGGCGTCTCTCAGTTCAGCGTCAAGGGCGACAAGGAGCAGAAGCTCCGCTTTGCGTTCAGGATTTATGACATGGATAAGGATGGCTACATATCCAACGGCGAGCTGTTCCAGGTGCTGAAGATGATGGTAGGGAATAACCTGAAGGACACCCAGCTGCAGCAGATCGTCGACAAAACCATCATCAACGCAGACAAGGACGGGGACGGGAGGATATCTTTCGAGGAGTTCTGCGCTGTGGTTGGTGGCTTAGACATTCACAAAAAGATGGTGGTGGACGTGTGAAGAGACGCAACAGGCCCTTCACTGAACACCCTCTTTTCACTTCTCCATTTCTGAGAATCAGCTCCAGATGTTCTGCTAACAcgctctctctatctctatctctctctcgctctctctctctgtctgtcgaTCTCTTTCAATGGAAGTATTTCTCTGAATGATGCCTCTGTTCCCCGTCTGTACTCCCTGAGCCTTGTGACGCCTGCCATCCTAAGTGTTATAGAGCATGAGATTCTTCTGTCCACGTTCTTGGGTATTTAAGGACAGTCAGAGAGACGATTTCTCTGTCGATTACCGAGCGATTCAGTGCGGTGGAGAAGGAAGAaaggagggtgtgtgtgtgtgtgtacgtgtgtgcctgtatgcatgtgtgtacgttctttaacttttttttgatggaggggttttttttgtatttattttggtcctgtctttttttttttaaagatgatctAGGTCTACAGGGAATACGTGTACGTGAGCGATAAACACACGACTTGACACTTGATTTCAGCGCGACACGCTTCGAGCATGAAGTGCCAATCCAGACATATACGTGGGATTTAACAATAGCTGAATACCGAAACCGCTAACCGATGTTCTTCATGTCACGgggagattaaaaaaagaaaaaaaaaaaaaaaaagtcatcgtcgagcttattgtttttttgtttccaccTAATATCTGCTTCAGATCTGACGCGAAATCCCATTCGAATTTTCTACGAgaatgtgtgcgtgtatgtaaaAGTGTGCCGTGTTAATATTGTCAGGGAGTTCATCTGCCGTCTTGCTTTCTGATATACAGTAGACtaggattaaaaaaacaaatatatttgaagTTGTGCACATATATACACGTATGGTTTACTTTTGAGGGGTCGGGTGGGGAGGGACGATCAGATCACACCACATGTTACTGTAGGATGGGACGGTGCCATCAGTAAAatttctcaacttttttttgtgtgtgtgtgttgtggatTTAGTACCATTTTACCACGGCAAACAAGTTTTTGATTTACCTCTCGACAATGTAGGACACAGTGCATATTGTGGCAAACTGAATCCACAATAACACCCGATTTGAATATTTGTTTGTGGAAATACaaggttaatttttttttccaacttgACTGCAGGCAGCATTGTAAAGACCTTAGTAGCTCATATTTGTATATTAGGGACTGAAGGACTGattgtgtgttttggtttttttttttttttttttttttctaagcttTAATCGAGTTGGTTCGCAGCATGTTACCCGAGAGTGATCGTCGAAGTAGACTAAGCAGACCTTGACTGACCGAtcagtttctcttttttccttcgTCATTTCAAAGATtcagttcaaaaaaaaaaaaaaaaagaggagagacCAAACCAGACGCTTTCAACGCGGACGAATAAACTCGAAGCGTTCGGCCACTCCGCTATTTCGCTTTTAAATGTGATTCTCCCGCGCAAACCGGCGTTTTTCCCGCCAGCTGCTGCACGGTGACGGCGCTTAAACATGTCTCTCCCGAAGGCCGCTGAGGTCTTGTGATGTGCTTGCATGATACGGGAgggtttctctctctttcttttctttctgttgtgCATGTagatcagatttttattttattttttattttcttgggGGAAGGGGGTTCTCTTGTTTACATATGAATCGTACTATTGAGATATTATTATACTCTGAATGacagttatataaatatatggacGTTGCCAAACTTTtggtaaatgtttaaatatgaaaattattttaaagcgaGTTTCTTCACTACATTTATccatacatattattattatttattattaaaaaaaaaaaatgcgagTTTTTTGGATTGGTGTCCGTCGCTCCCAGcgattttattttctctctttaaaaaaaaaaaaaaagagagggagttatgtttcatttttctcCTTTTCCGTTCATGGTTTGGTTGAGTCGTTTTGTACAGAATGTATGTTTGTTGCTTTCggttgttttgtatttctttagCTGGGGATCAGGCGGCCATCCGAGTAACTTCCGCTGCGAGAGCCGCGGGGTTTTTGGACAAAAGGAAACGTACAAGTGAATGAAAAAACGTTTCGCTTTTAGGTTTGAacgttttgtttctttcttcatttctcTGCATGCTGCGTCATATGCTGTGggaaccatttaaaaaaaatgtcattcatgAAAAcgagaaataaaatatttgagacTTGTA

Function

symbol description
ppp3r1a Predicted to enable calcium ion binding activity and calcium-dependent protein serine/threonine phosphatase regulator activity. Is expressed in brain. Human ortholog(s) of this gene implicated in Alzheimer's disease and dilated cardiomyopathy. Orthologous to human PPP3R1 (protein phosphatase 3 regulatory subunit B, alpha).
ppp3r1 Enables cyclosporin A binding activity; phosphatase binding activity; and protein domain specific binding activity. Involved in calcineurin-NFAT signaling cascade and positive regulation of transcription by RNA polymerase II. Part of calcineurin complex. Implicated in Alzheimer's disease and dilated cardiomyopathy.

NR:

description
PREDICTED: calcineurin subunit B type 1-like

GO:

id name namespace
GO:0045087 innate immune response biological_process
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway biological_process
GO:0007507 heart development biological_process
GO:0038095 Fc-epsilon receptor signaling pathway biological_process
GO:0001837 epithelial to mesenchymal transition biological_process
GO:0006470 protein dephosphorylation biological_process
GO:0001569 branching involved in blood vessel morphogenesis biological_process
GO:0060487 lung epithelial cell differentiation biological_process
GO:0097193 intrinsic apoptotic signaling pathway biological_process
GO:0042383 sarcolemma cellular_component
GO:0005829 cytosol cellular_component
GO:0005654 nucleoplasm cellular_component
GO:0005955 calcineurin complex cellular_component
GO:0005509 calcium ion binding molecular_function
GO:0005516 calmodulin binding molecular_function
GO:0019899 enzyme binding molecular_function
GO:0019904 protein domain specific binding molecular_function
GO:0004723 calcium-dependent protein serine/threonine phosphatase activity molecular_function

KEGG:

id description
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043239774.1 True 3045 mRNA 0.43 6 25509574 25522370

Neighbor

gene id symbol gene type direction distance location
spred2a spred2a,LOC107747416,LOC107675542,LOC107757033,LOC107583232 coding downstream 43108 25453204 ~ 25466466 (-)
LOC122329893 kif16b,LOC107594414,LOC107747412 coding downstream 284172 25208777 ~ 25225402 (-)
LOC122329700 sgms2,LOC107729360,LOC107675923,LOC107594470,LOC107684311,LOC107757011 coding downstream 370927 25134896 ~ 25138647 (-)
esf1 esf1,LOC107757029,LOC107747407,LOC107684260,LOC107675607 coding downstream 525544 24977040 ~ 24984030 (-)
jag1a jag1a,LOC107675628,LOC107594417,LOC107747432 coding downstream 558309 24923196 ~ 24951265 (-)
cnrip1a cnrip1a,LOC107676313,LOC107684253,LOC107594460,LOC107583248,LOC108258529 coding upstream 997 25523367 ~ 25526442 (-)
LOC122351449 fbxo48,LOC107747422,LOC107594409,LOC107675512,LOC107583249,LOC107684254 coding upstream 5109 25527479 ~ 25529540 (-)
snrpb2 snrpb2,LOC107684252,LOC107676294 coding upstream 39191 25561561 ~ 25563855 (-)
rnaseh2a rnaseh2a,LOC107747423,LOC107594406,LOC107676270,LOC107757040,LOC107583201 coding upstream 42017 25564387 ~ 25568911 (-)
junba junba,LOC107594404,LOC107757044,LOC107747424,LOC107684248,LOC107675464 coding upstream 54852 25577222 ~ 25578799 (-)
G6165 NA non-coding downstream 4720 25503940 ~ 25504854 (-)
G6118 NA non-coding downstream 81638 25283375 ~ 25427936 (-)
G6132 NA non-coding downstream 122998 25386177 ~ 25386576 (-)
G6125 NA non-coding downstream 192886 25314516 ~ 25316688 (-)
G6104 NA non-coding downstream 251267 25253397 ~ 25258307 (-)
G6200 NA non-coding upstream 97876 25620246 ~ 25620504 (-)
G6201 NA non-coding upstream 99064 25621434 ~ 25621745 (-)
G6223 NA non-coding upstream 214427 25736797 ~ 25737312 (-)
G6594 NA non-coding upstream 246537 25768907 ~ 25799273 (-)
G6634 NA non-coding upstream 313568 25835938 ~ 25844994 (-)
G6135 ndufaf5,LOC107675590,LOC107594415 other downstream 107219 25400384 ~ 25402355 (-)
G6134 ndufaf5,LOC107594462,LOC107594415,LOC107583196,LOC107684300 other downstream 109557 25398491 ~ 25400017 (-)
G6124 actr2,LOC108423375 other downstream 201603 25304597 ~ 25307971 (-)
G6089 cyp2u1,LOC107729355,LOC107583182,LOC107756983,LOC107683164 other downstream 375415 25132003 ~ 25134159 (-)
G6085 hadh,LOC107594428,LOC107729339 other downstream 381750 25126051 ~ 25127824 (-)
prokr1a prokr1a,LOC107594458,LOC107676304,LOC107747445,LOC107757000,LOC108441199 other upstream 25355 25547725 ~ 25556982 (-)
LOC122353196 zgc:136864,c26h19orf53,LOC107598479,LOC107700848,LOC107747197,LOC105901798,LOC106531096 other upstream 191732 25714102 ~ 25715704 (-)
patl1 patl1,LOC107598520,LOC107657997,LOC107594300,LOC107703847,LOC107746119 other upstream 308954 25831324 ~ 25863787 (-)
G6592 ucp1,LOC107730009,LOC107598545,LOC107703842,LOC107700810 other upstream 608418 26130788 ~ 26135486 (-)
smdt1b LOC107598503,LOC107700869,LOC107594281,LOC107746113,LOC107703822 other upstream 894489 26416859 ~ 26417897 (-)

Expression


Co-expression Network