melk (melk,LOC107709443,LOC107702285,LOC107570222)


Basic Information

Item Value
gene id melk
gene name melk,LOC107709443,LOC107702285,LOC107570222
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056699.1
NCBI id CM032068.1
chromosome length 31761587
location 12607766 ~ 12617282 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043243673.1
TCAAACAAACGCAAAACAGCAGAAGCTAACAGCTAActcatttacatttctgttttattcaaaccgatattaaataatgttattctGTTACGGGGGGGAACTCCTTCCACCTAGCGCAAAGGACTTTTACCGTAACAGGAAACAGGAACTCTTCTGACGTAGCAAGTGggaaattcaaatttttaaaacatgttcgAACGAAAGATGCTTCggcagttttaattttatatggCATTGAAAACACAACTAATCTGTGGTAACTGAGTAAATTATCTCCTCGCTTTAaaagcatatacattttattgttttattgttttgaactCGCTCATAACGGCGTTTTAAAGTGAACCATCGGAGCACAGCTGGTGTAAGTGTCCTCAGCATGCCTGTAGAAAGCACTTCAGAACTCCTCAGGCACTATGAGGTTTATGAAACCATCGGCTCAGGCGGGTTTGCCAAAGTCAAACTTGGTAGACACATACTGACAGGAGAGAAAGTGGCCATCAAAATAATGGAGAAGAAAGACTTAGGGGATGATCTCCCCAGAGTTAAGATAGAGATCGAGGCCATGAAGAACCTCAGTCATCAACACGTGTGTCGTCTCTACCATGTTATTGAGACATCAAGCAAGATCTACATGGTGCTTGAGTACTGTCCTGGAGGAGAGCTGTTCGATTATATCATCGCTAAAGACCGGTTGTCAGAGGAAGAGACCCGGGTGTTTTTCCGTCAGATCATCTCAGCGTTGGCTTATGTTCATAGCCAAGGCTATGCCCACAGAGACCTCAAACCGGAAAACCTGTTGATCGATGAAGATCATAACCTAAAACTCATTGACTTCGGCCTTTGTGCCAAACCAAAGGGCGGTTTGGGTTTTGAATTGCTGACCTGTTGTGGCAGTCCAGCATATGCAGCTCCAGAGCTCATTCAAGGCAAGGCTTACATTGGTTCTGAGGCTGATGTGTGGAGTATGGGAGTATTGCTTTACGCTTTACTGTGTGGTTTTCTTCCGTTTGATGATGACAATTGTATGGTACTCTACAGAAAAATCACTAGAGGCAAATATAGCAACCCCCACTGGCTTTCACCTGCCAGCATTCTGCTTCTGAACCAGATGATGCAGGTGGACCCAAAGAGGCGTTTGACTGTGAAACAATTGCTTGATCACCCTTGGGTCATGAAGGGATACAGTACACCAGTGGAGTGGCACAGTAAACATCCTTTGGGTCATATAGATGAAGACTGTATCACTGAAATGGCGGTGTCTTTTAAACAGTCCAGACAAAGGTCAATCCAACTTGTGTCAGAGtggaagtACGATCAAATGACCGCCACCTACCTGTTACTGTTGGCTAAGAAGCGTCAAGGCCGCCCCGTGCGTCTGAGAGCTGAACGCCCCATGATTGACCCCATGTACTCTCCATTACAGAACATACAACTGAAGAATAGTCTACGCTTcagtgaggatgatgatggtgtTCACCCAGTGGTGCTTGGCTCTATGGTCTTCCCCCCTGATTGCTACGATGACGAGAATCCCTGGACCCCTCTCACGCCcaagaacacacacaccacaaacacTCCACGCATGAAGCTCACCTCTGACACATCGGAGAAGCGGTGGAATGAAATGGGCTACTCCCCCATCATAGAGCAACGGAGACCCCGTAAACAGAAGCCAGAGAGACGTGATAGAGCcagagaaaataaagagaatcTTGCTGTGACGGCCACAGATGGAGATGTGTTTGCTCTGCCTGCTCCCCGAACTCCGATGTCCAGCAGAAAGACCAAATCCAACAGAAATGTAGTGACAACACCTAACAACAACATCACCACCACAAGCAGTGACGCAGGCAAAGGAGCGGGCAGTGCCACTAAAGAAGCGTCCCGCAGGAGAGAAGTGGACCAACAGCAGAGCGGTCAACAAGGAGAACTGGATATGCTGGCTTTCAGCCCAGAGAGAAGGTCTCGATCTCTGGACTTGGCTGGCTGTCAGGTGGACAGTGGGCAGAAGCGGAAGGGAGGTAAAGTGTTTGGCAGTCTGGAGAGAGGCCTGGATAAAGTTATTACAATGCTCACTCCCAGTAAGAGGAGAGGACTTCGAGACGGACCACGCAAAATTAAGgCTCAATACAACGTGACCCTCACCAGTCAAACCAATGCAGACCAAGTGCTCAATCAGATTCTCAGCATCCTTCCAGAGAAGAACGTGGACTTCGTTCAGAAGGGCTATACTCTGAAGTGCCACACGCAGTCGGACTTTGGAAAGGTGACCATGCAGTTTGAGCTGGAGGTTTGTATCCTGCAGAAGCCTGAGGTGGTCGGGATCCGTCGACAGCGGCTCAAAGGTGACGCCTGGGTGTATAAACACCTGGTAGAGGACATCCTGTCCACCTCCAGCATCTGATATCATTTCATCCACTTCAAGAGTGACATCACCTCCTGCCCGCCCTGACTTTAACACGGTGGACATACATTACAGAATGCCCTACTTTATGCGCCTTATGATGATATCCATCATTTTCCGTTATGCCCAGGAGGTGGTACAGTATTATTCTGCCTTTGAGAGAAGTGCAAGTATTTTGTTGTCACTTTACTTGTAATGACCTAATTCAGCTAATTCATATAGCATTAAGCAGCAGTTGTATCTTATTTgccttttgttttcatgtttgtctCCTTGACGTCAACGTCCGtcatgttttatgtgttttaatgtcatttttaatgtaaatttaatgtaGTGTAAAGTAATATGTTACCCTTTTCTAGATGTCTGTCATGTTTGCTTTTGATAATGTCAATATgacatgtaattaaataaatattttaacaccaTGTA

Function

symbol description
melk Predicted to enable calcium ion binding activity; non-membrane spanning protein tyrosine kinase activity; and protein serine/threonine kinase activity. Involved in hemopoiesis. Acts upstream of or within erythrocyte development and regulation of heart contraction. Predicted to be located in cell cortex. Is expressed in several structures, including digestive system; immature eye; nervous system; pleuroperitoneal region; and proliferative region. Orthologous to human MELK (maternal embryonic leucine zipper kinase).

NR:

description
PREDICTED: maternal embryonic leucine zipper kinase

GO:

id name namespace
GO:0018108 peptidyl-tyrosine phosphorylation biological_process
GO:0048821 erythrocyte development biological_process
GO:0043065 positive regulation of apoptotic process biological_process
GO:0007049 cell cycle biological_process
GO:0008016 regulation of heart contraction biological_process
GO:0046777 protein autophosphorylation biological_process
GO:0061351 neural precursor cell proliferation biological_process
GO:0005886 plasma membrane cellular_component
GO:0005938 cell cortex cellular_component
GO:0005509 calcium ion binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0008289 lipid binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004715 non-membrane spanning protein tyrosine kinase activity molecular_function

KEGG:

id description
K08799 MELK; maternal embryonic leucine zipper kinase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043243673.1 True 2845 mRNA 0.45 18 12607766 12617282

Neighbor

gene id symbol gene type direction distance location
zcchc7 LOC107709449,LOC107655886,LOC107548354 coding downstream 63625 12499771 ~ 12544141 (-)
adamtsl7 LOC107709448,LOC107750434,LOC107702297,LOC107570220 coding downstream 113441 12477518 ~ 12494325 (-)
LOC122342847 NA coding downstream 167321 12437822 ~ 12440445 (-)
LOC122342838 NA coding downstream 172868 12429730 ~ 12434898 (-)
ncapd3 ncapd3,LOC107655906,LOC107709432,LOC107750432,LOC107702392 coding downstream 188486 12407369 ~ 12419280 (-)
LOC122348170 frmpd1,LOC107709451,LOC107655878,LOC107548301,LOC107750435,LOC107702397,LOC107570223 coding upstream 1201 12618483 ~ 12643576 (-)
chrna8 LOC107709454,LOC107655813,LOC107548356,LOC107562618,LOC107702399,LOC108410819 coding upstream 107292 12724574 ~ 12772830 (-)
chrnb3a chrnb3a,LOC107562617,LOC107655822,LOC107548357,LOC107709455,LOC107702298,LOC107750476 coding upstream 161307 12778589 ~ 12794404 (-)
chrna6 chrna6,LOC107709456,LOC107655806,LOC107750436,LOC108260984,LOC108412407 coding upstream 199473 12816755 ~ 12823474 (-)
chrnb5a chrnb2a,LOC107548317,LOC107656869,LOC107709434,LOC107702400,LOC107562601 coding upstream 224970 12842252 ~ 12854994 (-)
G2889 NA non-coding downstream 12472 12592441 ~ 12595294 (-)
G2882 NA non-coding downstream 57527 12549922 ~ 12550239 (-)
G2842 NA non-coding downstream 152194 12455354 ~ 12455572 (-)
G2841 NA non-coding downstream 152997 12454231 ~ 12454769 (-)
LOC122348535 ncapd3,LOC107709432,LOC107702392,LOC107750432,LOC107655906,LOC107591581 non-coding downstream 163883 12427167 ~ 12443883 (-)
G2891 NA non-coding upstream 486 12617768 ~ 12618042 (-)
G3020 NA non-coding upstream 269494 12886776 ~ 12887653 (-)
G3070 NA non-coding upstream 588505 13205787 ~ 13206826 (-)
G3074 NA non-coding upstream 677415 13294697 ~ 13295015 (-)
G3080 NA non-coding upstream 685471 13302753 ~ 13313529 (-)
gria2a gria2a,LOC107548351,LOC107702389,LOC107745055,LOC107750427,LOC108443988,LOC107655932,LOC107591557 other downstream 241658 12337962 ~ 12366108 (-)
ugt8 ugt8,LOC107745064,LOC107656191,LOC107750420,LOC107702381 other downstream 490383 12097910 ~ 12117383 (-)
apela NA other downstream 819100 11783629 ~ 11788666 (-)
ptprdb ptprdb,LOC107754148,LOC107656000,LOC107746012,LOC107591569,LOC107551589 other downstream 1027049 11514151 ~ 11580717 (-)
G2584 LOC107656769,LOC107551593,LOC107746013,LOC107754144 other downstream 1094933 11510439 ~ 11512833 (-)
prom1b LOC107709459,LOC107671910,LOC107548362 other upstream 286917 12904199 ~ 12926482 (-)
smim18 NA other upstream 351811 12969093 ~ 12973012 (-)
smim14 smim14,LOC107757606,LOC107700293 other upstream 537204 13154486 ~ 13159444 (-)
G3072 NA other upstream 674014 13291296 ~ 13291723 (-)
LOC122350606 gatb,LOC107695556,LOC107695902 other upstream 1212181 13829463 ~ 13842664 (-)

Expression


Co-expression Network