smad2 (smad2,LOC107743055,LOC107653131)



Basic Information


Item Value
gene id smad2
gene name smad2,LOC107743055,LOC107653131
gene type misc
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_056708.1
NCBI id CM032077.1
chromosome length 16503406
location 2231422 ~ 2250897 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence


>TU109750
AGACGGCAGACGGTGACGAGCACCCCCTGCTGGATCGAGCTTCACCTGAACGGCCCCCTGCAGTGGCTGGACAAGGTCCTGACCCAGATGGGCTCGCCCTCCGTACGCTGTTCCAGTATGTCCTAATCGCCACGACCAAGCTCTCTGTCCCCCCCCTCCCCCAAACGACTGATTCTACAATCACATCAAGCGACAACTCGAAGAACAACAGACTTACTCGAACCCCCgcccctctttctctttcatagTAATCGTGAGCCTTTCTCTATCTTCTTCTCTCCTCCCGACACTGATGTTCTCTCCGTTCGGACCTGAACGCAGCACTTGCTGTCTCATCAGCTTCATGCACCTTTAAttctctcttgttttctttcataaaccctcaatattaaatgtattagtagtagaatttgaaatgtatattgggtttttttattttatttttatggttttcgAGAAGGAGGGAAGGTGCGTATGTTGTGTGGAAGTTCAAGAAGGCAGTAAATAACTTCACACACTTGTAGCAGCAAGGCTTTTCCCCCCTGATGAAGTAAATACTCTGATACTCTTTTAGCGATTAATTTTCCTGGATGCCGATCCCAATCCGGTTGTTCAAGGAGGTTACTTTTTCTGGCAAAAAGTCacattctttgtttttatacacGTTATTATTGTGTAGATTGACACGGTAAGACTTAATCATTGTgtttgattttcttcagtaatgccaaaagacttttattttgtttttattattattattattatattattattattttttttaccatttcttCCCCAAACCACTATATAAGAATGTTGCCTTTGATTTGAGGTATGCTGCTGTAAGTCATGCTTCTTTTCTTTAAACTTATAGAATGTttaacgcaaaaaaaaaaacaaaaaaagacccCACGTTCAATTGGAAACTTACGCTGCCCCTcagaattaactttttattcactGGGTGAAATATTCACTAGTTAGCTGTGGAGTGGTTTTGGAGTCTGGTTTCTTCAGAAAGTGGCTTCTTTTAGGGACTTTCGAAGGTTATTAAAGCGTCTCCTtgtgcagtccagatctttaaaataaaaatgacaaaagaataaaaaacaaatccaagTATTTAAGCTTTAAGTGTTAATAAACTAGGTTATCCTTCACAATTACAAGATTTTTTCCCTTTATCTTTCTTTTAGctactttttgtattttcatgtatttttatatataaatatatttaagatctTTAAAGCTCTCTTCCTTTTTATTagaattgaatatttttttagatcatGCCCtctttttaaaggaacatgGCTTCATAACGAAATGTCCTATCATACAAAAACGTTATTTAGCATGAACTTTTATAAACGCAAATatcttttctcctctttctccgCTTTCTAATTCAAGGTGTTGTCCCGGTTAACGTTTCGCCCTGATCTCGAACCCCCTGAAGTACATCCGACTCGAATTTTCTTTTCAGTTGCTTTCCTCCCATGTTCATCACACGATGCTGTATAACCCGCCGCCCCTCCAAGTACGGCTACCCGAAATCATGGCGGTGTTCTATTTGTTTGCAATTggggaattaaaaaaaattaaaagaataaaaaaacgaaaccgGTTGCTTTTACAGGGAGAACTGTGCAACTTTAGTGTGCGTGCTCGTTGTACAACTTTTACTAATGACTGTGATATAGCTGTCTGTTATTCTTTACTTGTTGTGGCAGTGACCAGGCGTTACAAATATCCATTCCCCTCTTTCCCACCTCTGTCTCCATATTTTCCTTCATTGAACTTAACTACTCTTGCGATTGTACTTTAAGTGCATCTAGTAAAAAGCTGACGAAGATGTTGTGGCCCGTTTTTAAAGCCGACGAGCGGCCGTTGAGACACTGGGAACATTCTGTTTGCCATTTTTGACTGGGTGTGGAAAGAAAACCAAATAGAACTGAAAGTGGACCagacatatatgcatataaatgtgtatatataattttattttaccttttttattttatttttttttctcctgtaattttttttttctcctgttttgCAAAGCATTTAACAGTTGGTGAGCTTGTTTTACCATTAGAGAGATGTATTGGTAGGACGTGAACTTCAGGCGATAAGCTTTTCAGGCGTGTTGCATATGCAGACTTCATAAATACactaataaaaagttttaattctC
>XM_043250492.1
GTTAGGTTGCGCGCGCTGGAGGCCGTCGTCTGCTGCTGTAATTCGGCTACAGTGGGAaggaaaatattgtttaaaatcgACTTTTACCCACTCGCGAATAATCCGTTTCGCTCGGATTTTACGCTGCTCCTTCCTTACAGAGAAAGCGGCTCGCCGAAAGGGCAGACCGGGACGGTGAGTCGATTAGCGGCCCATGCAGCCATAACGAGCCCGTGATACACCATCAGACCGCTGGAGAAGGTAACTCCTCGCCCCCCTTTCCTCTCCTGTTTCCTAAGCTTCTCTGTCCCCTGCCCCTCAAAATCAGCCCAGAGACCCTCTTCCTAAAGGCCAGTTAGGAACGTTGGGTCTGTTCCTCCCCATTCTCCCAGcctccatctgtctctctaACTCCACCTGCCCAGTAGGGGGCTGACCGCTTATTGGACACCCCAAAAACATGTCCTCCATCTTGCCTTTCACTCCGCCCGTGGTGAAGCGTCTGCTGGGCTGGAAGAAGTCGGCCAGCGGTTCGAGCGGAGCGGGAGGGGGCGGAGAGCAGAACGGCCAGGAGGAGAAATGGTGCGAGAAGGCCGTCAAGAGCCTGGTGAAGAAGTTGAAGAAGACGGGCCAGCTGGACGAGCTGGAGAAAGCCATCACCACACAGAACTGCAACACCAAGTGTGTCACCATCCCCAGCAATTGCTCTGAAATTTGGGGACTGAGTACACCAAATACGATAGAACAGTGGGATACCTCAGGCCTTTACAGCTACCCTGACCAAACCAGATCTCTGGACGGGCGTCTGCAAGTGTCTCACCGCAAAGGTCTGCCTCATGTCATCTACTGCCGCCTGTGGCGATGGCCCGACCTGCACAGCCATCACGAGCTGCGCGCCATCGAGACCTGCGAGTACGCCTTCAACCTCAAGAAGGATGAAGTCTGCGTCAACCCCTACCACTACCAGCGGGTGGAGACGCCAGTTCTTCCTCCTGTCCTCGTGCCAAGACACACAGAGATCCTGACTGAGCTGCCTCCTCTGGACGACTACACCAACTCTATACCTGAAAACACCAACTTCCCAACAGGGATCGAACCTCCTAACAATTATATACCAGAAACTCCTCCGCCTGGATACATTAGTGAGGATGGGGAGGCCAGCGACCAGCAGATGAATCAAAGTATGGACACAGGTTCTCCTGCAGAACTGTCCCCAAGCACACTCTCGCCTGTCAATCATGGCATGGACCTTCAGCCAGTGACTTACTCAGAGCCCGCGTTTTGGTGCTCCATAGCGTACTATGAACTAAACCAGCGGGTCGGAGAAACATTCCACGCCTCTCAGCCTTCCCTCACCGTGGACGGCTTTACAGACCCCTCCAACTCAGAGCGCTTCTGCCTGGGCCTGCTGTCCAACGTCAACCGCAACGCCACCGTGGAGATGACCCGAAGACACATAGGACGAGGGGTCAGGCTGTATTATATTGGTGGGGAAGTGTTTGCCGAATGTCTTAGCGATAGCGCCATCTTTGTTCAAAGCCCTAACTGTAATCAGAGGTATGGCTGGCACCCTGCAACAGTCTGTAAAATCCCTCCAGGCTGTAACCTGAAGATTTTCAATAACCAGGAGTTTGCGGCACTGCTGGCTCAGTCGGTGAACCAGGGCTTTGAGGCTGTATATCAGTTGACCAGGATGTGCACCATTCGTATGAGTTTTGTCAAAGGCTGGAGCGAGTACAGACGGCAGACGGTGACGAGCACCCCCTGCTGGATCGAGCTTCACCTGAACGGCCCCCTGCAGTGGCTGGACAAGGTCCTGACCCAGATGGGCTCGCCCTCCGTACGCTGTTCCAGTATGTCCTAATCGCCACGACCAAGCTCTCTGTCCCCCCCCTCCCCCAAACGACTGATTCTACAATCACATCAAGCGACAACTCGAAGAACAACAGACTTACTCGAACCCCCgcccctctttctctttcatagTAATCGTGAGCCTTTCTCTATCTTCTTCTCTCCTCCCGACACTGATGTTCTCTCCGTTCGGACCTGAACGCAGCACTTGCTGTCTCATCAGCTTCATGCACCTTTAAttctctcttgttttctttcataaaccctcaatattaaatgtattagtagtagaatttgaaatgtatattgggtttttttattttatttttatggttttcgAGAAGGAGGGAAGGTGCGTATGTTGTGTGGAAGTTCAAGAAGGCAGTAAATAACTTCACACACTTGTAGCAGCAAGGCTTTTCCCCCCTGATGAAGTAAATACTCTGATACTCTTTTAGCGATTAATTTTCCTGGATGCCGATCCCAATCCGGTTGTTCAAGGAGGTTACTTTTTCTGGCAAAAAGTCacattctttgtttttatacacGTTATTATTGTGTAGATTGACACGGTAAGACTTAATCATTGTgtttgattttcttcagtaatgccaaaagacttttattttgtttttattattattattattatattattattattttttttaccatttcttCCCCAAACCACTATATAAGAATGTTGCCTTTGATTTGAGGTATGCTGCTGTAAGTCATGCTTCTTTTCTTTAAACTTATAGAATGTttaacgcaaaaaaaaaaacaaaaaaagacccCACGTTCAATTGGAAACTTACGCTGCCCCTcagaattaactttttattcactGGGTGAAATATTCACTAGTTAGCTGTGGAGTGGTTTTGGAGTCTGGTTTCTTCAGAAAGTGGCTTCTTTTAGGGACTTTCGAAGGTTATTAAAGCGTCTCCTtgtgcagtccagatctttaaaataaaaatgacaaaagaataaaaaacaaatccaagTATTTAAGCTTTAAGTGTTAATAAACTAGGTTATCCTTCACAATTACAAGATTTTTTCCCTTTATCTTTCTTTTAGctactttttgtattttcatgtatttttatatataaatatatttaagatctTTAAAGCTCTCTTCCTTTTTATTagaattgaatatttttttagatcatGCCCtctttttaaaggaacatgGCTTCATAACGAAATGTCCTATCATACAAAAACGTTATTTAGCATGAACTTTTATAAACGCAAATatcttttctcctctttctccgCTTTCTAATTCAAGGTGTTGTCCCGGTTAACGTTTCGCCCTGATCTCGAACCCCCTGAAGTACATCCGACTCGAATTTTCTTTTCAGTTGCTTTCCTCCCATGTTCATCACACGATGCTGTATAACCCGCCGCCCCTCCAAGTACGGCTACCCGAAATCATGGCGGTGTTCTATTTGTTTGCAATTggggaattaaaaaaaattaaaagaataaaaaaacgaaaccgGTTGCTTTTACAGGGAGAACTGTGCAACTTTAGTGTGCGTGCTCGTTGTACAACTTTTACTAATGACTGTGATATAGCTGTCTGTTATTCTTTACTTGTTGTGGCAGTGACCAGGCGTTACAAATATCCATTCCCCTCTTTCCCACCTCTGTCTCCATATTTTCCTTCATTGAACTTAACTACTCTTGCGATTGTACTTTAAGTGCATCTAGTAAAAAGCTGACGAAGATGTTGTGGCCCGTTTTTAAAGCCGACGAGCGGCCGTTGAGACACTGGGAACATTCTGTTTGCCATTTTTGACTGGGTGTGGAAAGAAAACCAAATAGAACTGAAAGTGGACCagacatatatgcatataaatgtgtatatataattttattttaccttttttattttatttttttttctcctgtaattttttttttctcctgttttgCAAAGCATTTAACAGTTGGTGAGCTTGTTTTACCATTAGAGAGATGTATTGGTAGGACGTGAACTTCAGGCGATAAGCTTTTCAGGCGTGTTGCATATGCAGACTTCATAAATACactaataaaaagttttaattctCATGTTAA

Function


symbol description
smad2 Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic pattern specification and intracellular signal transduction. Acts upstream of with a positive effect on nodal signaling pathway. Acts upstream of or within negative regulation of transcription by RNA polymerase II; neural plate anterior/posterior regionalization; and positive regulation of oocyte development. Located in chromatin and nucleus. Is expressed in brain; head; immature eye; and tail bud. Human ortholog(s) of this gene implicated in Lynch syndrome; cervical cancer; and ovarian cancer. Orthologous to human SMAD2 (SMAD family member 2).

NR:

description
PREDICTED: mothers against decapentaplegic homolog 2 isoform X2

GO:

id name namespace
GO:0007179 transforming growth factor beta receptor signaling pathway biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0009880 embryonic pattern specification biological_process
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process
GO:0060282 positive regulation of oocyte development biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0046872 metal ion binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG:

id description
K04500 SMAD2; mothers against decapentaplegic homolog 2

RNA


RNA id representative length rna type GC content exon number start site end site
TU109750 False 2206 lncRNA 0.38 1 2248685 2250890
XM_043250492.1 True 3930 mRNA 0.45 14 2231422 2250897

Neighbor


gene id symbol gene type direction distance location
cldn23.1 LOC107738848,LOC107743003,LOC107558707,LOC107663452,LOC107548653 coding upstream 38130 2191117 ~ 2193292 (+)
cldn23.2 LOC107743020,LOC107663454,LOC107738849,LOC107548654,LOC107558708,LOC107667276 coding upstream 41233 2186592 ~ 2190189 (+)
wu:fk95d07 NA coding upstream 52295 2177613 ~ 2179127 (+)
spp1 LOC107667251,LOC107558676,LOC107726553,LOC107548657,LOC107705045,LOC107743181 coding upstream 71217 2155398 ~ 2160205 (+)
pum3 pum3,LOC107742987,LOC107705054,LOC107726546 coding upstream 150427 2073668 ~ 2080995 (+)
skor2 LOC107738854,LOC107558682,LOC107743073,LOC107653123 coding downstream 82747 2333644 ~ 2345527 (+)
ier3ip1 ier3ip1,LOC107738842,LOC107743093,LOC107653125,LOC106633120 coding downstream 95123 2346020 ~ 2347849 (+)
hdhd2 hdhd2,LOC107738843,LOC107743237 coding downstream 97101 2347998 ~ 2351666 (+)
galt galt,LOC107653127,LOC107667272,LOC107573074,LOC105911052,LOC107756536 coding downstream 112952 2363849 ~ 2453610 (+)
LOC122352383 musk,LOC107653500,LOC107756538,LOC107702603,LOC107723318 coding downstream 559675 2810572 ~ 2825957 (+)
LOC122352695 NA non-coding upstream 104952 2123034 ~ 2126470 (+)
G74229 NA non-coding upstream 108518 2122646 ~ 2122904 (+)
G74228 NA non-coding upstream 116490 2114453 ~ 2114932 (+)
G74227 NA non-coding upstream 117185 2112627 ~ 2114237 (+)
G74225 NA non-coding upstream 120972 2110091 ~ 2110450 (+)
G74336 ier3ip1,LOC107738842,LOC107743093,LOC107653125,LOC106633120 non-coding downstream 95152 2346049 ~ 2349195 (+)
LOC122352630 NA non-coding downstream 102951 2353848 ~ 2362914 (+)
G74372 NA non-coding downstream 211556 2462453 ~ 2462667 (+)
G74373 NA non-coding downstream 212098 2462995 ~ 2463410 (+)
LOC122352387 NA non-coding downstream 269486 2520383 ~ 2576082 (+)
G74171 NA other upstream 30955 2194097 ~ 2200467 (+)
G74226 sh3bp2,LOC107743173,LOC107705055 other upstream 119728 2111196 ~ 2111694 (+)
LOC122352734 LOC107744074,LOC107597614,LOC107686419,LOC107685127,LOC101884949,LOC107713324,LOC107595548 other upstream 1147383 1077696 ~ 1084039 (+)
rbm18 rbm18,LOC107597621,LOC107595545,LOC107685132,LOC107686423 other upstream 1285562 934069 ~ 945860 (+)
fstb fstb,LOC107685190,LOC107713293,LOC107686430,LOC107744087,LOC107597631,LOC107595577 other upstream 1429499 796011 ~ 801923 (+)
cntfr cntfr,LOC107554853,LOC107738850,LOC107756542,LOC107554231 other downstream 338199 2589096 ~ 2705724 (+)
il11ra LOC107756541,LOC107554229,LOC107750187,LOC107653503 other downstream 526962 2777859 ~ 2780475 (+)
LOC122352855 LOC107702575,LOC107715854,LOC107732942,LOC107569381,LOC107653476,LOC100002406 other downstream 1318381 3569278 ~ 3574352 (+)
enoph1 enoph1,LOC107702573,LOC107715850,LOC107679042,LOC107731803 other downstream 1337347 3588244 ~ 3617516 (+)
lyrm7 lyrm7,LOC107732862,LOC107715852 other downstream 1337521 3588418 ~ 3590111 (+)

Expression



Co-expression Network