sppl3 (sppl3)


Basic Information

Item Value
gene id sppl3
gene name sppl3
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056708.1
NCBI id CM032077.1
chromosome length 16503406
location 5333010 ~ 5357455 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043251132.1
GCACGCGCACTCCTCTGGCAGGGGCGACAGTCGCGCGCTCCCGTGCGTTCGCCATAGAAAACAAAGCTATCCGAGCGCTTCCATTACAAACCCAGCGCACAGCTCTCTCTCTGCATGCACACCCAAGATGGGTTTGCAGCTCATCTGAGGGCCTTTGAAAGCGGGGCCTGTTGCGAGGACAGTCAGCCAGCTGAAGTCAGCGAAACGTTTCgggatttttttctctccccgGACTGCTTTTGTTTCTTAGCCGCGGCTAGCAGCACAGCTACAATAATTGTCATTTCTGCTGCGAGCTGCCGAAGGAAAACACATCGCCATGTTGTTATCGGAGGGGGCTCAGTGAAGAAGGCGAAAACCGTGAGCGTGTGGAGGAGATAATCTCATCGTTTGAGCCCAACCTGAGTCCTCAGCCGCtgcctgactgactgactgacatgGCGGAGCAGAGCTACTCCTGGGCGTACTCCCTCGTCGACTCTAGCCAGGTGTCAACCTTCCTCATCTCCATCCTTCTCATCGTCTATGGCAGCTTTAGATCATTAAACATGGACTGTGAGAACCAGGAGAAGGACAAGGATGGAAACCCCACCGCCACTGGCTCCTTCAACAATGCCAACTCTAACAACAGTATTCAGACCATAGACTCCACACAGGCCCTGTTCTTGCCCATCGGAGCCTCTGTGTCTCTGCTCgtcatgtttttcttctttgacTCGGTTCAGGTGGTGTTCACCATATGCACTGCAGTTCTAGCGACCATCGCGTTTGCATTTCTCCTGCTGCCGATGTGCCAGTATCTGACCAGGCCCTGCTCCCCACAGAACAAGATCTCTTTCGGCTGCTGTGGCCGCTTTACATTGGCGGAGCTGCTGtcgttttctctctctgtcatgcTGGTTCTCATCTGGGTGCTGACGGGCCACTGGCTGCTCATGGATGCTCTTGCCATGGGTCTTTGTGTGGCCATGATTGCATTTGTGCGACTGCCCAGTCTCAAGGTGTCCTGCCTGCTGCTGTCGGGCCTTCTCATCTATGATGTGTTCTGGGTCTTCTTCTCCGCCTACATTTTCAACAGTAACGTGATGGTGAAGGTGGCCACTCAGCCTGCTGACAACCCCCTTGATGTGCTCTCACGCAAGCTGCACCTGGGCCCTGGCATGGGACGGGATGTCCCCCGTCTCTCCCTGCCAGGAAAGCTGGTGTTCCCCAGCTCCACCGGCAGCCACTTCTCCATGCTGGGCATTGGTGATATCGTCATGCCGGGCTTGCTGCTGTGCTTTGTGCTCCGATACGACAACTATAAGAAACAGGCCACTGGAGAGGTGCCCGGTCCTGTCAACATGTCCGGACGCATGCAGCGGGTTTCCTACTTTCACTGCACCCTGATTGGTTACTTTGTTGGTCTGTTGACTGCAACTGTGGCCTCTCGTATTCACCGCGCAGCCCAACCTGCTCTCCTGTACCTGGTGCCCTTCACCCTGCTGCCTCTGCTCACCATGGCCTACCTGAAGGGCGACCTGCGGCGCATGTGGTCTGAGCCCTTCCATGCCAAGTCCAGCAGCTCCCGCTTCCTGGAGGTATGATGCTGCTCCGACCATCACAAGTTCCCGCCATCCCACTGTTCCTAcccaccagagagagagagagagagagagagagaaagcgagagagaagTCGGAAGAGAGGAACTGCACTTGTCTTCTCATCATCCCTCATTCCCGTTGTCATCCTCCAGCCAGTGGATGAGCAGCTGCACTGGACTTCACTGCCAGATGGATTCATGCACTCCTCTCGTCTCTcttggtcttttttttcttctacctCTTTTCTTTCTAAGCTCCATTCCACCTTTATCCCCCCAACTTTCTCTCTCGCTTCTATCCCATCATCCCATTCATTCCTGTTCCACCGGACTCGGCCGCTTTTTACCGGATTGTTCTTCATCTGGACGTAAACCGGAGCCCCTTTGAGCTCCAAGTGTGTTTCCATTTGTACCGTTTGGCACCATTACGGATTTACAGACTgagatttctttatttcctgCTCTAAATGAACTGTGTACGAGGAACGTAGGTTCTGCCACAGCTTGGGATGACGATGACCCTATAAGGGACCAGCACACAATAGAGGACAGCGTCGTTTTCCCCTTTCCTTCCCTcattctctcttcctttttccCTTTCTGATAAAATCCAACCCGCATCCACCCCTTCCTCTCGCCAGATTCCCTCTCTAACAGCCCCTCCTTTGCagaaacatgtattttatttagaaagattTTATTCTTGGCATATACAGAAATGATGCATTATAAATTGTGGGGGCGTACAGctctatgtatatatgtgtacacaTGTATTAGGGGTTATCATGTCGaggtgcaagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgcgagtgcgtgtgtatgaaagaaaatgcatttaaacaggaAACcggttttcattttgttacttttagatctcagaatgcacatttttctctCGTAAATTGCTCTGCCTAggtcactttctttttcttttcttttttttctctccatatTCCGTAAAATTTATTGCGCATCGCCATTCAGTTTGGCTACTGAAGTCAAGATTCTGTGattcatgtttgtgtttttgtatgaaTGTATGCCGTTGCCTCCACGGGCTCTGGATGGACCACTGAAGGCAAGCTCCATTGTGCTAATGGAGGGAAATGTTTATGGATTGTACTAAGCTCAGTTATTTAAACAGGCCGAATTTTTTCCACTAGTATTTCAAGtatttgtttttggggtttttttggtttttcatttGTAGTCATTCCTTTAATCCAATTGGCTCTGTAATGGTGAAACTGGAATTGAAGTGCAAGATTGAGAGAGAgcgaacgagagagagagagagtgtgtgtgtgcgtgtgtgtgtaatgttgtaaaaaatattgcattttgctGGCTCAATCTGTTGAGTTtagcttttttcttctttttttcgttccttttttttttttttctttttttacctgttGTTACCCGTTTTTTAATCTGTTAGTCGTCTGGCCTTGCATGTCAATTGTACAGCGTGTCGTTCTTCAAAGCTGCGTTTTCCAGGGCAAGCGCACTAGTGCGACACTCTGAAACTCTGAGACGCAGACACGGGGTCATGGACGAAGACTCGCACAAGAGAATTTATGAAGCGGAGAGGAGCAACAAGTCAGGACCGCTCTGATCCCCTCGGCCGGCTTGGACCTCGCGCAAACATTGGCACTGCGTTGCCCGAATATTCAGTATGAACGTTTGCCTGGCAGTGGGATACTTAACCTGAGCATCACGGACATCATTTTACCCACAAACCTCCTTTTCACTGTCCCTCTGCCACCCTTACAGACAttacgaggaaaaaaaaaacaatataaatgacGATCATGACGATTGCATtgaaagtaaactttttttttcttttttttttttttttaatcgaagattgcattttgtttttgttttatcccattgtttgtattttttctccACTTTCTTCCCCTAATGCTGTggttttttttcgttttgtactaagggttttttttttcttctccgtCGTCCTCCCCGCCTGCAGAGGGCGCAAAGCTCTGATGGGCGATCAACATTAACAGCCAAAAGgattctgtataaaaaaaaattgaataaattaaagtgtAGTGAAATGTGGATCCAAATGAGCTGTACTGAAGACATTTCAGCTCTCATAACCTTCCCTTTCTTCTTAGTCAGGATTCTGCTGTAAATAAACATGACTCTAACTGTA

Function

symbol description
sppl3 Predicted to enable aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Acts upstream of or within regulation of neuron apoptotic process. Predicted to be located in rough endoplasmic reticulum. Predicted to be active in Golgi-associated vesicle membrane. Predicted to be integral component of cytoplasmic side of endoplasmic reticulum membrane and integral component of lumenal side of endoplasmic reticulum membrane. Is expressed in central nervous system. Orthologous to human SPPL3 (signal peptide peptidase like 3).

NR:

description
signal peptide peptidase-like 3 isoform X4

GO:

id name namespace
GO:0006509 membrane protein ectodomain proteolysis biological_process
GO:0043523 regulation of neuron apoptotic process biological_process
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane cellular_component
GO:0005791 rough endoplasmic reticulum cellular_component
GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane cellular_component
GO:0030660 Golgi-associated vesicle membrane cellular_component
GO:0042500 aspartic endopeptidase activity, intramembrane cleaving molecular_function
GO:0042803 protein homodimerization activity molecular_function

KEGG:

id description
K09598 SPPL3; signal peptide peptidase-like 3

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043251132.1 True 3808 mRNA 0.48 10 5333010 5357455

Neighbor

gene id symbol gene type direction distance location
LOC122352997 LOC107711241,LOC107672456,LOC107588012,LOC107670466,LOC107757355,LOC107567234 coding upstream 265473 5058497 ~ 5067537 (+)
si:dkey-210j14.3 LOC107672496,LOC107757375,LOC107711244,LOC107711245 coding upstream 283861 5046251 ~ 5049149 (+)
LOC122352867 LOC107711243,LOC107672495,LOC107587952,LOC107757372,LOC107567248,LOC107670491 coding upstream 287472 5038846 ~ 5045538 (+)
LOC122352868 LOC107587995,LOC107711162,LOC107672432,LOC107757375,LOC107587996 coding upstream 294505 5035033 ~ 5038505 (+)
LOC122352870 NA coding upstream 298526 5032154 ~ 5034484 (+)
kcnn2 si:dkey-76p7.5,kcnn2,LOC106564970,LOC107687918,LOC107686472,LOC107567448,LOC106563202 coding downstream 54228 5411683 ~ 5446436 (+)
drg1 drg1,LOC107744129,LOC107567440,LOC107713382,LOC107555524,LOC107687909 coding downstream 89876 5447331 ~ 5451955 (+)
slc20a1b LOC107686476,LOC107744132,LOC107687859,LOC107713386,LOC107555522 coding downstream 107502 5464957 ~ 5477005 (+)
pigo pigo,LOC107713385,LOC107686475,LOC107744133,LOC107687847 coding downstream 125310 5482765 ~ 5491729 (+)
phf24 phf24,LOC107677982,LOC107713387,LOC107744162 coding downstream 161713 5519168 ~ 5545588 (+)
G74958 NA non-coding upstream 97055 5235599 ~ 5235955 (+)
G74914 NA non-coding upstream 224896 5107785 ~ 5108114 (+)
G74908 NA non-coding upstream 234446 5097644 ~ 5098564 (+)
G74906 NA non-coding upstream 245419 5087280 ~ 5087591 (+)
G74902 LOC107560569,LOC107739969 non-coding upstream 258804 5073928 ~ 5074206 (+)
G74992 NA non-coding downstream 25684 5383139 ~ 5385855 (+)
G75007 NA non-coding downstream 98916 5456371 ~ 5458861 (+)
G75067 NA non-coding downstream 206248 5563703 ~ 5638236 (+)
G75076 NA non-coding downstream 285434 5642889 ~ 5643101 (+)
G75077 NA non-coding downstream 286094 5643549 ~ 5643766 (+)
G74965 NA other upstream 74187 5256838 ~ 5258823 (+)
LOC122352567 ywhah,LOC107562560,LOC107744159,LOC107713377,LOC107555530,LOC107688000 other upstream 82873 5238279 ~ 5250137 (+)
LOC122352404 LOC107670527,LOC107567246,LOC107587997,LOC107757377,LOC107711240,LOC107672489 other upstream 209637 5116866 ~ 5123373 (+)
LOC122352783 tln1,LOC107715875,LOC107670039,LOC107568645,LOC107702558 other upstream 804008 4481267 ~ 4529002 (+)
LOC122352388 tln1,LOC107715875,LOC107670039,LOC107568645,LOC107702558,LOC107737170 other upstream 1212563 4013034 ~ 4120447 (+)
ccl19b LOC107744181,LOC107677997,LOC107567444,LOC107555521,LOC107713300,LOC107688602,LOC107713257 other downstream 141192 5498647 ~ 5500388 (+)
G75062 LOC107744182,LOC107678054,LOC107567441,LOC107713390,LOC107687817 other downstream 203196 5560651 ~ 5562085 (+)
lrrtm4l1 lrrtm4l1,LOC107730422,LOC107553720,LOC107687748,LOC107720738,LOC107561403 other downstream 703736 6061191 ~ 6089587 (+)
LOC122352486 LOC107720590,LOC107677990,LOC107553711,LOC107705075,LOC107586209 other downstream 1096610 6454065 ~ 6472107 (+)
trpc7a trpc7a,LOC107677994,LOC107720592,LOC107552051,LOC105905985,LOC108437819,LOC106603261 other downstream 1624037 6981492 ~ 6993621 (+)

Expression


Co-expression Network