XLOC_006630 (plaua)


Basic Information

Item Value
gene id XLOC_006630
gene name plaua
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 25297257 ~ 25305179 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012797
GACAGCAAGTGCTTAGTAAGCCCAGTAGAGCTCTACACAGCAGCATCTGCAGGAAAACAGAAAGATCAGCTGTGTCTACTATAAGAAAGGATctccaaaaaaggaaaaaaaaaaaaacattggtttgCCATCAAGATGAAGTGTATACTAGGGGGTTTTCTGCTCACATGTGTCCTGTGCTGGACTGAAGCAATCATAGGAGAGATGGATGAAAGGTGGAAATCTTCTTCAACTTCTGTAAATGGCAAGTGCATATTAGACAGAGATGAGAGCAAATACACAGGAAAAGTGTCAGTGACTGTCAGTGGACGGATTTGTGCACCATGGAATTCCATCCAAGGCTCACGATACTCTGCCTTCAAAAACTGTTATCATAACTACTGCAGGAATCCAGATGACTGGACTCAGCCATGGTGCGTTGTAAAGAAAAGAAACCGTTATGTACGTGAATACTGTAACATACCTCAGGAGGCAATAAAGCCAGTCAAACGTCCACCAACACCCGAGCCAATAAAGCAGGACACAGAATTAACGTGTGGGGAGCGCCGCTTGGACCGACAGACAAAGATAATAGGAGGATTAAGGTCAACTGTTGAGTCACAGCCTTGGATGGCAGCTATCTTTAAAGGAGATGGGTTCATTTGTGGAGGAACCCTCATCACTCCATGCTGGGTCCTCACTGCAGCCCACTGCTTCCCTACTGGtaaaagaacacaaataaatagatacTCTGTCGTCTTGGGAAAGAATGCCATCAATGAAACCGACCCAGTCAAAGAGCAGAAATTCACAGTGAGCAGACTTGTCATCCACGAGGACTTTGACTACTCAACTGAAAACTACACTCACGACATTGCTCTGTTGAAGATAGAGGACTGCAATGGACAATGTGCAGTAAAGACAAAAACTGTAAGAACTGCGTGTCTTCCTCCTTTCCAGCAAATGCTTCCTGTTGGATTCTACTGTGAGATTGCTGGTTACGGAAGATATCAAAAGGGTACCTTTAAGTTCTCTAGATATCTGAAGCAAACTGAAGTCAAGCTTATTTCCCAAAAAGTTTGCCAGAGAACGTATTACAATAAGGACGAGGTCAATGAAAACATGCTGTGCGCAAATGGTAGAGACTGGAAAACAGATGCTTGCCAGgGTGACTCAGGAGGGCCCCTGGTGTGTGAAGTAAATAACATCATGTTCCTATTTGGCATCATAAGCTGGGGAAAAGAGTGTGCAGAAAAAAATCAGCCCGGTGTTTACACACAAGTCAGCAACTACAATCAGTGGATCTCACAGCACACTGGTTTGCCTAGATATACAGCAGGCTCCAGGTACCCACAAAAGGACTAACTATGACTGAACAAATGCTTAGTGACTCAGGGTAATGTTTCAGCCTGCACAGAATGCACGTGCCAATTATTTATCCCATTCGCATTATATATGGCAGCTACCTCTTCAATCAATAGGAATAATCTTTAACAGTGCTGTAATCGTATTCATATATCGGACAGTGTTACTAGTGGTGTATATGAAGGATATGTAGAATGAGTGTACGACCATGTTTATAGCAATAAGCATGTTATAAGTGCTCCACAAAGGTACATTTGTTCATTTGGCTGGgcattatgtttgtttgttttattaattgtttttttaatataatatattatttaatatttatataataatgtatgtaggatgaatgtgtttatttttttaacacttcTTATTCTAAATCTATGTTTTATATGAAAGTCTCCTTTCCAAGTTTATGGACTTGCAATGTATTATATTTGACATTAAACTTGCTTTAAGTCTCTTCAtgtttttgttcattaattttgcATCATATTTTCTCTACATTACAAGCAACATGCATTTTCACTTATGCATTCAAGTTCTTATTAACCAATTGATTCATCTATTAGTCTAAGAGGAATTCAGACAATattcatacagtatatatttatggTCATGTCTGCCAATAAGATTGTTGTTCATGCAAAATATCAATTGTAAATTCActatttgtcaaatatttttggACATATGCCTTTATGTGCACATGAACTTTAATGGCATCCAAATTTTGATGAGTAGGGCTTACCAATTAGTTATTTCCGAATGAGGAAATTTATTGAATAGACATATTGCATCATGGTTGAATTCACAGAGGTCCTACAAGCAACTCATTTTTTTCTACAATGTTTCTTGAAGCAGTCTGCATGTCTAGGTACTGGACTGTATACAGCATTCtgagtattaaaatattaattctgttatcatttacagTTAAGAACTTGAGAAAAATTAACATGATTTGTTTTAGAAATAGTgtaatattaagattttattaAATGTAGTTGTAGCTTTACCATGCTCAAACAAGTGTTTAACAAAATGCCCTtgtaact
>TCONS_00012798
GAAAAGTGTCAGTGACTGTCAGTGGACGGATTTGTGCACCATGGAATTCCATCCAAGGCTCACGATACTCTGCCTTCAAAAACTGTTATCATAACTACTGCAGGAATCCAGATGACTGGACTCAGCCATGGTGCGTTGTAAAGAAAAGAAACCGTTATGTACGTGAATACTGTAACATACCTCAGGAGGCAATAAAGCCAGAATTAACGTGTGGGGAGCGCCGCTTGGACCGACAGACAAAGATAATAGGAGGATTAAGGTCAACTGTTGAGTCACAGCCTTGGATGGCAGCTATCTTTAAAGGAGATGGGTTCATTTGTGGAGGAACCCTCATCACTCCATGCTGGGTCCTCACTGCAGCCCACTGCTTCCCTACTGGtaaaagaacacaaataaatagatacTCTGTCGTCTTGGGAAAGAATGCCATCAATGAAACCGACCCAGTCAAAGAGCAGAAATTCACAGTGAGCAGACTTGTCATCCACGAGGACTTTGACTACTCAACTGAAAACTACACTCACGACATTGCTCTGTTGAAGATAGAGGACTGCAATGGACAATGTGCAGTAAAGACAAAAACTGTAAGAACTGCGTGTCTTCCTCCTTTCCAGCAAATGCTTCCTGTTGGATTCTACTGTGAGATTGCTGGTTACGGAAGATATCAAAAGGGTACCTTTAAGTTCTCTAGATATCTGAAGCAAACTGAAGTCAAGCTTATTTCCCAAAAAGTTTGCCAGAGAACGTATTACAATAAGGACGAGGTCAATGAAAACATGCTGTGCGCAAATGGTAGAGACTGGAAAACAGATGCTTGCCAGgGTGACTCAGGAGGGCCCCTGGTGTGTGAAGTAAATAACATCATGTTCCTATTTGGCATCATAAGCTGGGGAAAAGAGTGTGCAGAAAAAAATCAGCCCGGTGTTTACACACAAGTCAGCAACTACAATCAGTGGATCTCACAGCACACTG

Function

symbol description
plaua Predicted to enable serine-type endopeptidase activity. Acts upstream of or within plasminogen activation. Predicted to be active in extracellular space. Is expressed in several structures, including eye; gill; gonad; heart; and liver. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease (multiple); Quebec platelet disorder; end stage renal disease; lung disease (multiple); and mitral valve prolapse. Orthologous to human PLAU (plasminogen activator, urokinase).

GO:

id name namespace
GO:0031639 plasminogen activation biological_process
GO:0006508 proteolysis biological_process
GO:0016310 phosphorylation biological_process
GO:0033628 regulation of cell adhesion mediated by integrin biological_process
GO:0005615 extracellular space cellular_component
GO:0016740 transferase activity molecular_function
GO:0004252 serine-type endopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008236 serine-type peptidase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-090313-278 Predicted to enable serine-type endopeptidase activity. Acts upstream of or within plasminogen activation. Predicted to be active in extracellular space. Is expressed in several structures, including eye; gill; gonad; heart; and liver. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease (multiple); Quebec platelet disorder; end stage renal disease; lung disease (multiple); and mitral valve prolapse. Orthologous to human PLAU (plasminogen activator, urokinase).

Ensembl:

ensembl_id ENSDARG00000075265

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012797 False 2408 mRNA 0.38 11 25297257 25305179
TCONS_00012798 True 972 mRNA 0.44 7 25298368 25303303

Neighbor

gene id symbol gene type direction distance location
XLOC_006629 NA coding downstream 12541 25210158 ~ 25284716 (-)
XLOC_006628 adka coding downstream 97997 24918096 ~ 25199260 (-)
XLOC_006627 kat6b coding downstream 390950 24881272 ~ 24906307 (-)
XLOC_006626 kat6b coding downstream 416732 24871050 ~ 24880525 (-)
XLOC_006625 AL929334.1 coding downstream 426972 24830737 ~ 24870285 (-)
XLOC_006631 itprip coding upstream 98234 25403413 ~ 25408387 (-)
XLOC_006632 tial1 coding upstream 166826 25472005 ~ 25484752 (-)
XLOC_006633 BX005252.1 coding upstream 225355 25530534 ~ 25530648 (-)
XLOC_006634 mcmbp coding upstream 225825 25531004 ~ 25548882 (-)
XLOC_006635 csgalnact2 coding upstream 264652 25569831 ~ 25581303 (-)
XLOC_006471 BX537274.2 misc downstream 15032352 10264741 ~ 10264905 (-)
XLOC_006338 rn7sk misc downstream 24471032 825904 ~ 826225 (-)
XLOC_006619 NA non-coding downstream 674032 24590420 ~ 24623225 (-)
XLOC_006620 AL831745.2 non-coding downstream 690630 24602410 ~ 24606627 (-)
XLOC_006618 AL831745.1 non-coding downstream 709037 24585224 ~ 24588220 (-)
XLOC_006617 NA non-coding downstream 719235 24577265 ~ 24578022 (-)
XLOC_006640 NA non-coding upstream 471210 25776389 ~ 25778815 (-)
XLOC_006643 NA non-coding upstream 541353 25846532 ~ 25853311 (-)
XLOC_006644 NA non-coding upstream 704318 26009497 ~ 26703804 (-)
XLOC_006645 NA non-coding upstream 1228175 26533354 ~ 26544816 (-)

Expression


Co-expression Network