acvr1l (acvr1l,LOC107678695,LOC107749086,LOC107602619,LOC107721710,LOC107690001)



Basic Information


Item Value
gene id acvr1l
gene name acvr1l,LOC107678695,LOC107749086,LOC107602619,LOC107721710,LOC107690001
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_056700.1
NCBI id CM032069.1
chromosome length 25613461
location 20294585 ~ 20303774 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence


>XM_043223947.1
CGTCACGGCGCAGTCTTTTCAGTCTCTCTGGGTGGCGGCAGACAGTCTGTCAGCGCCTAAAACACGACTCcgaataaaacagtaaaaactcGGGACGTTACCACAAACATGAATCTGCGTCGCAGCTAAAGGATCCAATGGGAAGGCAGAGTCTGGCTGTGTGCATACTGAAAGGTAGCGCTGAGAGTCACCTGAGAAGTTGTACAATGCAGTGAACCAAATGGGGCATTGCAGTACTCAAATCATCGTCCTATTCCTGCTTCAATTCTTACGGACATCAGCTAAAGATGTCTCCATCGACTGCATGTGTGTCGGCAGCGACTGTAATGAGCAGCAGTGCATCGGAGATCAGTGTTACACCTCTGTTATCATTAGCAATGATGTGACAACATTCAAACGTGGCTGCCTTATTGGGCCGGAGAGCAAGCGCATGACTTGCTCCGCAACACCCTCGGCTAGTCATGTCGTCGAATGCTGCTCTCAACATATGTGCAACGCCAACGTCTCCAAAGAGACCCTTCTTCGACTGCTGCTGACAAGTCCAGAAGGACAGGCAGCTGTGCATTACCGTGTGGAGATGCTGGTTCTCTTTGTGTTGGGGCCTTTTGTGGTTCTGGGTTTGCTGTCTGTGCTGGCTTTGCTGGTGTGCCGTAGACTTCATCACGGTCGTCTGGAAAGATTGCACGAGTTTGACACTGAGCAGGGGGCCATTGATGGGCTCATTGCATCTAATGTCGGAGACAGCACACTTGCGGATCTGATGGATCACTCCTGCACATCAGGAAGTGGTTCAGGACTGCCCTTCCTGGTTCAGAGGACGGTTGCACGGCAGATCAGCCTGGTAGAGTGTGTCGGTAAGGGACGGTATGGGGAAGTGTGGAGAGGTCAGTGGCAAGGAGAGAATGTAGCCGTGAAGATCTTCTCTTCCAGAGATGAGAAGTCATGGTTTAGAGAGACCGAAATATATAACACCGTTCTACTACGCCATGAAAATATATTGGGATTCATGGCTTCTGATATGACCTCCCGAAACTCTAGCACTCAGCTGTGGCTCATCACACACTACCATGAGAACGGCTCACTCTACGACTACCTGCAGCGTGTTGCTGTGGAGATGGCAGATGGACTGCACATGGCGGCGTCAGTAGCCAGCGGGCTGGTGCACCTGCACACGGAGATCTTTGGCACTGAGGGCAAACCGGCCATCGCTCACAGAGACCTGAAGAGCAAGAACATCCTGGTGAAGAAAGATCTGCAGTGCTGCATCGCTGATCTGGgtCTGGCAGTAACGCACACGCAGTCTGACAATCAGCTGGATGTGGGAAATAATCCTAAAGTGGGAACTAAGCGCTACATGGCACCAGAGGTTCTAGATGAGACCATTCAGACAGACTGTTTTGATGCCTATAAGAGGGTGGACATCTGGGCCTTTGGGCTGGTGCTGTGGGAGATCGCTCGTAGAACCATCAGTAACGGAATTGTAGAAGAATACAAGCCGCCTTTCTACGACCTGGTGCCTAATGACCCCAGCTTTGATGACATGAGGAAAGTGGTTTGTGTGGAGCAACAAAGGCCGTTTATTCCCAACCGCTGGTTTTCAGATCCTACCCTGTCTGCTCTGGTGAAGCTGATGAAAGAGTGCTGGTACCAGAACCCCTCGGCTCGACTCACCGCCCTGCGCATCAAAAAGACTCTGGATAAAATCCACAGCTCACTGGAGAAGGGCAAAACCGACTGCTGAGGAGAGAGAGCCGCAGAACTACTGACCGCTCACCCGCTCATTCTACAGACACTGTGTAACCAGACCGTTGGATTCGAGCTCTGGCATCTGTCCCAACTCTAACATGCTGTTTATTCGCTTTGTTCTTCCTGTCCATTGGCCTAAAAACTTTTTATAGAGAATTACCCTCTCTTTTTATGGAAAATTTTTCCCACTGAACCCGGTGGGACTCCCATTTCCCCCTCCAGAAACAGCGTAAAGGAGAAAAATACGGACACGGTCTGACAGGCCTTGAATTGAACCCTTCATGGAATTTTTTTAGCGCCATCACATTGTCTATTCAACCATTGGCAAACTTTTAAGATTTGTACTTTTCGGAAAAATTGAAGAGGATGGATACACACGCCGAAATAcccatagtgtgtgtgtgtgtgtgtgagtgtgtgcatgatTCTTAATGCAACCAGAAGAACTTTAAAGCTGTAATGTCACTTGCTTTTAGAAATCTGATGTTTTTGAGCTTTTCAAAGATTCTTGTAGATAAATAGGCAAAAATAAGTCACCGTTTCTGAATTTGCTATAGTGGACTTGTGTTATAAAGCTCTTTGGTTACAAAATGCCACTATGTACAGTAGAGAAGTACAGACTAGTGTCTTTAATTAGGCCTGTTTAGTGATCAGAATAGAGTGGTTAAAAAggtagttcactcaaaaatgcaaaatctgTCATCAGTCCTGTCATTCTAAAGtttaataacagaaaaagaCGTTGCTCTTTTTCCACAGGTCAAGTGCATATAGTGACCAGGGACTGTCAGGGTCCCTGAAAGTGAAAGAAACATCGTCAAATAAGGTTATGAAATGgcatgatgacagaattaattttttgtgtgtgaacttTCTCTTTATCCCAGTCTGGTCATGCTCATGGCACCCCATGAGGGCTTCCTTTGACACAAGGCCTTTCTGACCTGTTGCCTCTATGCCTGCCTGACAAAAGCCATTGTAGCACATcgtagtgctttttttttgtagccgtttgtctttctctttgcCCTCACCGGCATGCGTACTTGATGTTTGTTCACTGACAATCAGCCGCTGTCAAATAGGGCCTGAATTATTTGCTAATGTTATGTACAAAAACCCTACTTAGGAGTGTCCAAGGTGTCGTGTCAACACATTAACATATTCATAGTCAGAAACAGACTCTGGTTTTGTgaatttgcatatttgtttacTCTTACGCTTTTTGACACTTTTGTACCACATGCGCCATAAACCGAGAGAACGCTGatgatttttaaatttgaaacgTTTTGGACTATTTAAAAGTGCAACGTCACTCTAATATAGGATCTATGAGGTTTAAGAAGGAAAACATTACTGCTTTGTCCCAAGTCGAAATGGTTTGTGTACGTTGCTTTTGGTTTGGGTTGAGTTGTGTGGCGTTTTATTAAGAATTCGTTGATGCTTTCATGACACACTACATGAGGCGGCTGCGTACCGCTCAACACTGGTCACTTTTGCTCTCCCAAAAATGGACGAACGTTTACATATTTGTGTTCCACAGGGGAACGATGTTAGGAATTAGAGTAAAGGAATTGTTGCGTTATGAACTGTGAATATGTTATAATGAAGAAACCGTATGTATGATGTTACTGGAATATAAATGCAAGACACggttatgaatttaaaaaaaatgctctttTCATTCGTTAAAACATTGAAATGGTTTTTCTGTCACGTGCTTGTGCTTAACAAAAGGTTGCCCATGCTGTGATAATGCTTTCTTTTTAGCTGTAAATTTTAAGAATCGTGTTTTGCGGATTATCATGCATCTGTCTTGCATTTTCCTGTACAGGGAGATGAGCTAAATGAAGCATTAGGAAAAGGTTCCCCATTGTCTGAGTCTGCTGGGAAATGACCTTCTTATCTCTGGTGATGTTTACAGGAGGTCTGCAGCCGCTCTCTGATAACCAGTGCTATTATAGCTGGTAGTACAACAGCTGAAGCTAATGAGAACGTAAATGCCAACTGATTTGAAGATGCAAGATCAGTTGTAGTCCGCGTTAGCAACCATCTTTAAAAACTGGATCTGAAATAAGCCAAGATGTAGTTCCGCTGCTTTCTTTTCGGATGTAGTTTTCCTATAGAAAGGCACATTTGTTTTCCGTTTAGCACGACGGACAGATCCTTTATGAATTTGTATGCGATTGGGGGGTTCATCAGTTTATGCCATGAAAATGGCTTCAGCCATTgttaaccaaaatattttattgtctaAATGGATTGAACAACTTTGTTAGTGAGGATCATTAGACACGATTTGGTGTATAtacatgctgtaaaataaaatctcatgCTGAGCTTTCGTTTGAA

Function


symbol description
acvr1l Predicted to enable ATP binding activity; SMAD binding activity; and transforming growth factor beta receptor activity, type I. Acts upstream of or within several processes, including animal organ development; embryonic morphogenesis; and regionalization. Located in cell cortex. Part of BMP receptor complex. Is expressed in brain; ceratobranchial 5 tooth; immature eye; liver; and tooth placode. Human ortholog(s) of this gene implicated in fibrodysplasia ossificans progressiva. Orthologous to human ACVR1 (activin A receptor type 1).

NR:

description
activin receptor type-1-like

GO:

id name namespace
GO:0003342 proepicardium development biological_process
GO:0021556 central nervous system formation biological_process
GO:0003140 determination of left/right asymmetry in lateral mesoderm biological_process
GO:0003146 heart jogging biological_process
GO:0046588 negative regulation of calcium-dependent cell-cell adhesion biological_process
GO:0042475 odontogenesis of dentin-containing tooth biological_process
GO:0051216 cartilage development biological_process
GO:0048264 determination of ventral identity biological_process
GO:0030510 regulation of BMP signaling pathway biological_process
GO:0051260 protein homooligomerization biological_process
GO:0006468 protein phosphorylation biological_process
GO:0003230 cardiac atrium development biological_process
GO:0009952 anterior/posterior pattern specification biological_process
GO:0035124 embryonic caudal fin morphogenesis biological_process
GO:0048332 mesoderm morphogenesis biological_process
GO:0001889 liver development biological_process
GO:0035162 embryonic hemopoiesis biological_process
GO:0060030 dorsal convergence biological_process
GO:0001944 vasculature development biological_process
GO:0001947 heart looping biological_process
GO:0035462 determination of left/right asymmetry in diencephalon biological_process
GO:0005938 cell cortex cellular_component
GO:0070724 BMP receptor complex cellular_component
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0005024 transforming growth factor beta-activated receptor activity molecular_function

KEGG:

id description
K04675 ACVR1, ALK2; activin receptor type-1

RNA


RNA id representative length rna type GC content exon number start site end site
XM_043223947.1 True 4101 mRNA 0.45 11 20294585 20303774

Neighbor


gene id symbol gene type direction distance location
epha4b epha4b,LOC107694655,LOC107668971,LOC108428906,LOC108268054,LOC103372263 coding upstream 548690 19644610 ~ 19745895 (+)
LOC122324221 NA coding upstream 663455 19629741 ~ 19631130 (+)
LOC122357116 NA coding upstream 669247 19622041 ~ 19625338 (+)
LOC122326186 NA coding upstream 674693 19618385 ~ 19619892 (+)
ccl20l LOC107708274,LOC107668934,LOC107583148,LOC107706309 coding upstream 692641 19600097 ~ 19601944 (+)
odf3l2a zgc:110183,LOC107749223,LOC107602632,LOC107721708,LOC107588920,LOC107690329,LOC107678684 coding downstream 129695 20433469 ~ 20435422 (+)
vcpip1 vcpip1,LOC107567007,LOC107721719,LOC107659314,LOC107690121,LOC107749097,LOC107602633 coding downstream 216135 20519909 ~ 20529006 (+)
LOC122358486 LOC107602635,LOC107566996,LOC107721759 coding downstream 233763 20537537 ~ 20539554 (+)
LOC122355453 NA coding downstream 240052 20543826 ~ 20547503 (+)
LOC122355454 cyp7b1,LOC107749124,LOC107659553,LOC107602637,LOC107566988,LOC107690180,LOC107721742 coding downstream 246169 20549943 ~ 20555995 (+)
G13768 NA non-coding upstream 678530 19613459 ~ 19616055 (+)
G13769 NA non-coding upstream 681680 19612269 ~ 19612905 (+)
G13748 NA non-coding upstream 753607 19538570 ~ 19540978 (+)
G13690 NA non-coding upstream 1131243 19163105 ~ 19163342 (+)
G13682 NA non-coding upstream 1161449 19132729 ~ 19133136 (+)
G13829 znf622,LOC107678698,LOC107602620,LOC107588872 non-coding downstream 8272 20312046 ~ 20314981 (+)
G13821 NA non-coding downstream 13407 20317181 ~ 20321388 (+)
G13857 NA non-coding downstream 159964 20463738 ~ 20463959 (+)
G13874 NA non-coding downstream 161753 20465527 ~ 20465846 (+)
G13851 LOC107721736 non-coding downstream 174189 20477963 ~ 20499950 (+)
rem2 LOC107583115,LOC107567555,LOC107668956,LOC107738122,LOC107706340 other upstream 2132443 18138644 ~ 18162142 (+)
nedd8l nedd8l,LOC107591390,LOC104949953,LOC104931181,LOC107559219 other upstream 2423169 17870258 ~ 17871416 (+)
G13137 NA other upstream 2477821 17784179 ~ 17816764 (+)
LOC122325453 LOC107668965 other upstream 2512221 17779339 ~ 17782364 (+)
G13111 LOC107738210,LOC107591364 other upstream 2686493 17607252 ~ 17608092 (+)
crlf1a crlf1a,LOC107602622,LOC107678692,LOC107588877,LOC107690059 other downstream 112429 20416203 ~ 20429348 (+)
gbp2 LOC107678697,LOC107602627,LOC107690079,LOC107721763 other downstream 163494 20467268 ~ 20473524 (+)
G13882 LOC107749119,LOC107602627,LOC107721764,LOC107659530,LOC107721763 other downstream 177890 20481664 ~ 20485218 (+)
LOC122326305 LOC107749119,LOC107602627,LOC107566983,LOC107690079,LOC107721763,LOC107721764,LOC107678697 other downstream 189400 20493174 ~ 20508391 (+)
G13998 LOC107659744,LOC107749160,LOC107563810,LOC107563823 other downstream 860168 21163942 ~ 21164822 (+)

Expression



Co-expression Network