Item | Value |
---|---|
gene id | ptenb |
gene name | pten,ptenb,LOC107669198,LOC107584135,LOC107594163 |
gene type | coding |
species | tiger barb (Puntius tetrazona) |
category of species | ornamental fish |
Item | Value |
---|---|
chromosome id | NC_056710.1 |
NCBI id | CM032079.1 |
chromosome length | 20499150 |
location | 7720387 ~ 7735245 (-) |
genome version | ASM1883169v1_2021_tiger_barb_Genome |
symbol | description |
---|---|
ptenb | Enables lipid phosphatase activity. Acts upstream of or within several processes, including lifelong otolith mineralization; negative regulation of angiogenesis; and phosphatidylinositol dephosphorylation. Predicted to be located in PML body and cytoplasm. Predicted to be active in several cellular components, including cytosol; nucleus; and plasma membrane. Is expressed in several structures, including adaxial cell; blastomere; nervous system; neural rod; and pectoral fin. Human ortholog(s) of this gene implicated in several diseases, including Cowden syndrome; breast cancer (multiple); gastrointestinal system cancer (multiple); nervous system cancer (multiple); and reproductive organ cancer (multiple). Orthologous to human PTEN (phosphatase and tensin homolog). |
pten | Enables several functions, including PDZ domain binding activity; anaphase-promoting complex binding activity; and phosphatase activity. Involved in several processes, including dephosphorylation; negative regulation of cell migration; and regulation of cellular protein metabolic process. Acts upstream of or within negative regulation of protein kinase B signaling. Located in several cellular components, including apical plasma membrane; cytoplasmic side of plasma membrane; and nucleoplasm. Implicated in several diseases, including Cowden syndrome; PTEN hamartoma tumor syndrome; breast cancer (multiple); nervous system cancer (multiple); and reproductive organ cancer (multiple). Biomarker of several diseases, including PTEN hamartoma tumor syndrome; gastrointestinal system cancer (multiple); in situ carcinoma (multiple); reproductive organ cancer (multiple); and urinary system cancer (multiple). |
description |
---|
PREDICTED: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X2 |
id | name | namespace |
---|---|---|
GO:0030097 | hemopoiesis | biological_process |
GO:0046855 | inositol phosphate dephosphorylation | biological_process |
GO:0046856 | phosphatidylinositol dephosphorylation | biological_process |
GO:0006470 | protein dephosphorylation | biological_process |
GO:0001568 | blood vessel development | biological_process |
GO:0031647 | regulation of protein stability | biological_process |
GO:0008285 | negative regulation of cell population proliferation | biological_process |
GO:0051895 | negative regulation of focal adhesion assembly | biological_process |
GO:0051898 | negative regulation of protein kinase B signaling | biological_process |
GO:0060027 | convergent extension involved in gastrulation | biological_process |
GO:0030336 | negative regulation of cell migration | biological_process |
GO:0031174 | lifelong otolith mineralization | biological_process |
GO:0008138 | protein tyrosine/serine/threonine phosphatase activity | molecular_function |
GO:0030165 | PDZ domain binding | molecular_function |
GO:0051800 | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity | molecular_function |
GO:0042577 | lipid phosphatase activity | molecular_function |
GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | molecular_function |
GO:0004725 | protein tyrosine phosphatase activity | molecular_function |
GO:0000287 | magnesium ion binding | molecular_function |
id | description |
---|---|
K01110 | PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN |
RNA id | representative | length | rna type | GC content | exon number | start site | end site |
---|---|---|---|---|---|---|---|
XM_043253669.1 | True | 5514 | mRNA | 0.40 | 10 | 7720387 | 7735245 |
XM_043253670.1 | False | 5445 | mRNA | 0.40 | 9 | 7720387 | 7735245 |
gene id | symbol | gene type | direction | distance | location |
---|---|---|---|---|---|
lipf | lipa,lipf,LOC107753430,LOC107584137,LOC107594160,LOC107758444 | coding | downstream | 57656 | 7651748 ~ 7662731 (-) |
stambpl1 | stambpl1,LOC107594159,LOC107758441,LOC107669191,LOC107683716,LOC107584140 | coding | downstream | 73596 | 7636843 ~ 7646791 (-) |
ifit9 | LOC107669232,LOC107753434,LOC107584193 | coding | downstream | 106020 | 7612135 ~ 7614367 (-) |
ifit10 | LOC107584141,LOC107753434,LOC107669232,LOC107758418,LOC107594210,LOC107683722 | coding | downstream | 108395 | 7609394 ~ 7611992 (-) |
LOC122355798 | LOC107753456,LOC107669160,LOC107584195,LOC107594195 | coding | downstream | 111671 | 7604853 ~ 7608716 (-) |
papss2b | papss2b,papss2,LOC107680272,LOC107753426,LOC107724695,LOC107584134,LOC107594166,LOC107669161 | coding | upstream | 12347 | 7747592 ~ 7754731 (-) |
minpp1b | minpp1b,LOC107669175,LOC107753454,LOC107753455 | coding | upstream | 19612 | 7754857 ~ 7760517 (-) |
usp42 | usp42,LOC107753425,LOC107669212,LOC107724691,LOC107584191 | coding | upstream | 43051 | 7778296 ~ 7789396 (-) |
eif2ak1 | eif2ak1,LOC107753420 | coding | upstream | 54342 | 7789587 ~ 7795766 (-) |
dlgap5 | LOC107669214,LOC107584128,LOC107699863 | coding | upstream | 72417 | 7807662 ~ 7815339 (-) |
G86357 | NA | non-coding | downstream | 12193 | 7707860 ~ 7708194 (-) |
G86356 | NA | non-coding | downstream | 14904 | 7705221 ~ 7705483 (-) |
G86354 | NA | non-coding | downstream | 21373 | 7698665 ~ 7699014 (-) |
G86333 | acta2,zgc:86709,actc1a,actc1,ACTC1,LOC107594158,LOC103374497,LOC108414322,LOC106531354,LOC107683715 | non-coding | downstream | 84243 | 7634638 ~ 7636144 (-) |
G86334 | NA | non-coding | downstream | 85831 | 7631396 ~ 7634556 (-) |
G86375 | NA | non-coding | upstream | 111236 | 7846481 ~ 7846832 (-) |
G86412 | NA | non-coding | upstream | 152721 | 7887966 ~ 7888246 (-) |
G86413 | NA | non-coding | upstream | 155058 | 7890303 ~ 7891221 (-) |
G86458 | NA | non-coding | upstream | 319523 | 8054768 ~ 8055031 (-) |
G86516 | NA | non-coding | upstream | 375948 | 8111193 ~ 8112713 (-) |
G86203 | NA | other | downstream | 331477 | 7388236 ~ 7388910 (-) |
G86108 | NA | other | downstream | 616169 | 7103880 ~ 7104218 (-) |
G86049 | LOC101886504,LOC101886427 | other | downstream | 1049140 | 6670319 ~ 6671247 (-) |
LOC122355418 | pnmt,LOC107571312,LOC107676565 | other | downstream | 1642319 | 6051168 ~ 6078068 (-) |
G85930 | LOC107711793,LOC107755027 | other | downstream | 1708276 | 5990913 ~ 6012111 (-) |
cpped1 | cpped1,LOC107584109,LOC107669238,LOC107554009 | other | upstream | 599159 | 8334404 ~ 8359992 (-) |
LOC122355061 | tnfrsf17,LOC107554040,LOC107692075,LOC107690067,LOC107584106,LOC107734209 | other | upstream | 776158 | 8511403 ~ 8513265 (-) |
G86783 | cby1,LOC107554026,LOC107734186,LOC107584208,LOC107690074 | other | upstream | 875307 | 8610552 ~ 8612445 (-) |
plbd1b | LOC107578697 | other | upstream | 947198 | 8682443 ~ 8687548 (-) |
trnar-ccu_66 | NA | other | upstream | 952253 | 8687498 ~ 8687570 (-) |