top2a (top2a,LOC107598028,LOC107660475,LOC107091052)


Basic Information

Item Value
gene id top2a
gene name top2a,LOC107598028,LOC107660475,LOC107091052
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056710.1
NCBI id CM032079.1
chromosome length 20499150
location 3917420 ~ 3931659 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043254134.1
tgaaatttgaaaatcGGTTACTACTGCTTCGTTTTAATCGCGCGTGTGTTCGTAAGGTTAGTTCAGATAGTTTGAAACAACTTTAATTAGGAAAGCTAGTGATTTGATATAGTTGAAGGCATATTTGTTCGTATTATAGTTTCATTCGCTTAGGTCGTGCGAGAggtaaacagtaaaaaatggcTGGAACTGAAGGACCTCTGAagAGTTTGTTTGAAAATAAGGCTCTCAGTAAGACCAAGAAAGATGATAAGCGTCTGTCTGTGGAAAGGATCTATCAAAAGAAGACCCAGCTGGAGCATATTCTGCTCCGGCCTGACACCTACATAGGCTCTGTGGAGCCTGTTACCCAGCAAATGTGGGTATTTGATGAGGCTATGGGAATGAACTGCAGAGACATCACGTTTGTCCCAGGACTCTACAAGATCTTCGACGAGATTCTCGTGAATGCTGCTGATAACAAACAGAGGGACAAAACTATGAACTGCATCAAGGTCAACATTGACTCGGAGAATAACACCATCAGTGTGTGGAACAACGGAAAGGGTATTCCTGTGGTTGAGCACAAGGTGGAAAAAGTATATGTTCCTGCTTTGATCTTTGGCCAACTCCTGACCTCCAGTAACTACGATGATGATGAGAAGAAGGTCACAGGCGGCCGTAACGGATATGGTGCAAAGCTGTGTAACATCTTCAGCACCAAGTTTACAGTGGAGACTGCATGCCGAGAGTCAAGACACTGTTTTAAACAGACATGGTTTGATAACATGGGCCGAGCAGGCGAGTGCAAGATCAAATCCTTTGATGGCGACGACTATACCTGCATCACCTTCCAGCCGGACCTGGCAAAGTTTAAGATGCAAGTTTTAGATAAAGACACTGTCGCACTGCTGACTCGAAGAGCGTATGATATCGCTGGGGCTACTAAGGGTGTCCGTGTCTTTCTAAATGGCAAAAAGCTGGCTGTTAATGGTTTCCGTAGCTATGTGGACTTGTACCTAAAGGAAAGGGTGGATGAGACCGGTTCTCCCCTGACAATAGTCCATGAGATCGTAAATGAACGCTGGGAGGTGTGTCTTACCCTTAGTGATAAAGGGTTCCAGCAAGTCAGCTTCGTTAACAGCATCGCCACGACTAAGGGTGGCAGACATACTGACTATGTTGCGGACCAGATCGTGTCCAAACTGATTGAAGTTGTGAAAAAGAAGAACAAGGCTGGAGTGGTTGTCAAACCTTTTCAGGTGAAGAACCACATGTGGTTGTTTGTGAACTGTCTGATTGAGAACCCCAGCTTTGACTCTCAGACCAAAGAGAACATGACATTACAGCATAAGAATTTTGGCTCCACCTGCTCTCTGAGTGACAAGTTTGTTAAACAGGCTAATAACTGTGGAATCGTGGAAAGCATTATGAACTGGGTGAAGTTTAAAGCCCAGGCTCAGCTCAATAAGAAATGCTCTGCTGTCAAACACACTAAGATTAAAGGAGTACCCAAGCTGGATGACGCCAATGATGCAGGTGGGAAGAACTCCACTAGCTGCACTCTGATCCTGACAGAAGGAGACTCGGCCAAAACTCTGGCTGTGTCGGGTCTGGGTGTTGTGGGACGTGACCGCTATGGTGTCTTTCCTCTGCGTGGTAAAATTCTCAATGTTCGAGAGGCATCACATAAACAGatcATGGAGAATGCTGAGATCAACAACATCATAAAGATCCTTGGTCTGCAGTACAATAAGAACTACAGTGCACCTGAGTCACTCAAGAGCCTGCGCTACGGCAAGCTCATGATCATGACAGATCAGGATCAAGACGGATCTCACATTAAAGGTCTTCTCATCAACTTCATACATCATAACTGGCCATCACTGCTGCGCCACAACTTCCTAGAAGAGTTTATCACACCTATCATCAAGGCATCCAATAAGAAGCAGGAGCTTTCTTTCTACAGTATCCCAGAGTTCAATGAGTGGAAGGAGAAACAAAGTAGCATAAAATCCTGGAAGATCAAATACTACAAAGGTTTGGGTACCAGCACATCTAAGGAGGCCAAAGAGTATTTTTCGGATATGACAAGACACCGAATCCCTTTTAAGTACTCTGGGCCAGCTGATGATGAAGCTATCACCCTGGCCTTTAGTAAGAAAATGGTAGATGAGAGGAAGGAATGGCTGACCAGCTTCATGATCAACAGACGTCAGCGCAGAGAACACAACCTGCCTGAGGAGTACCTGTACGGACAGGAAACGACATCCCTCACCTACCATGATTTTATCAATAAAGAGCTTGTGTTGTTCTCCAACTCTGACAATGAGAGATCACTCCCCTGCTTGGTGGACGGTCTAAAACCAGGCCAAAGGAAAGTACTGTTCTGCTGTTTTAAGAGGAATGATAAAAGGGAGGTGAAAGTGGCTCAATTGGCAGGATCAGTGGCTGAgatgtcagcataccaccatGGAGAGgtCTCTCTGATGATGACCATTGTGGGTCTTGCTCAGAACTTTGTGGGCAGTAATAATTTGAACCTGCTCCAGCCTATGGGTCAGTTTGGCACACGTCTGCATGGTGGCAAAGACTCTGCCAGCCCCAGATACATCTTTACCATGCTCAGTCCACTTGCTCGTCTTCTGTTTCCTGCTGTGGACGATAACCTTTTGAAATATAACTACGATGATAATTTGCGAGTGGAGCCGGAGTGGTACATGCCCATCATTCCTCTGCTGCTGGCTAATGGAGGTGAGGGCATCGGCACAGGATGGGCCAGCCGCATCCCCAACTATGACGTGAGGGAGATCATCAACAATATTCACAGAATGCTCAATGGAGAAGATCCACTTCCCATGCTGCCAAGCTATAAGGGCTTCAAAGGCACCATTGATGAATTGGCAAAGAATCAGTATGTGAATAATGGAGAGGTGGCCATCATTGACTCTACTACTATTGAGATCACTGAACTGCCAATCAAAACCTGGACACAGATCTACAAGGAGAATGTATTGGAGGCAATGCTGAATGGCACGGAGAAGGTTCCTTCTTTGATCACAGACTATAAAGAGTATCATACAGACACCACGGTGCGTTTCGTCATAAAGATGACTGAGGAGCGCTTAAAAGAGGCTGAGGCAGCTGGATTACATAAAGTCTTCAAACTACAGAATCTGCTCACCTGTCACTCCATGGTGTTGTTTGATCATGTGGGCAGTCTGAAAAAGTATGAGTCTGTTCAGGACATCTTGAAGGATTTCTTTGAGCTCAGAATGAAGTATTATGTCCTCAGAAAAGACTGGCTGCTAGGCATGCTGGGGGCTGAAAGTGCCAAACTTTCCAACCAGGCCCGATTCATTCTGGAAAAGATCCAGGGCACACTGGTCATTGaaaataaacctAAGAAGGAGCTGATCCGCATGCTTCAGCAGATGGGCTATGACTCAGACCCTGTTAAGGGCTGGAAAGATGCTCAAGAGAAGGATGCAGAAGAGGATGACGACGAGGAGGAGAAGGATAAAGAGGAGGCATCTGGCCCTGATTATAACTATCTACTCAGCATGCCCATGTGGTACCTgaccaaagaaaagaaagatgagcTGTGCCGACAGAGAGATGCTAAGATGACCGAGTTGAACACGCTCAAGATGAAAGCCCCTGCTGATCTGTGGAAAGAGGATCTGGCAAACTTTACAGAGGAGCTTGAGCGTTTGGAACAGAAAGAGATGGAGTCACAAAATGCAGTGCCTGTGGTGAAGGGTAAAGTGGGCAAATCAAAGGTGGTGAAGATGAAGAACGAGACCATGCCCACTCCACAGGGCCGCCGTGTCATCCCCCGCATCACCAGCACCATGAAGGTCCAGGCTGTTAAGAAGGAGGGAGCCAAACGAGGCAAAGCTGTGAAGaaagaggCTGATGTGGTGATGAAGATGGAGTTTGATGATGAAGCAGATGCAGCAGTCAATAGCTCTGAGATGGGACTGACTGCAAGACTCACTAAGAAGGTCAAGAAAGAGCCAGCCAAAGCAAAAGGAACAAAGTCAGGCAAGCAGACCACTCTCTCCTTTAAACCGGTCCAGAAGAAAAACCCCTGGTCTTCTGATGAGGGAGAGTCTGAGTCTGACAGTGAGCTCATCCCTGAGGAAGTGGCTccaagagaaaagagagagcgtAAAGCTGCGGTGGAAAAGAAGTACAGTCTGTCGAGCAGTGAAGATGAGTTTGATGTCTGGACAAAGAGCTCTAAACAGAAGCGCGCTATCATTGAGGATGACGAGTCCTTCCTCCCAGAACCCAGCGGTGCACCTGATAGTGACATTGACTCTCCTCCTCCCGCACCTGTTGTgaaAAAAGCCCCAGCAAAAGCCAGCAAACCAAAAGTAGAGAAACCCGAAGCCAGTAGCAAGTCCGGCTCTGAGACCAGCCAAGAACCGGCCCCTAAACCAGTGAAAAAAACAGCCGTAGGAGCCACCAAGAAACTGCCCGTAAAGACAAGTGCTGCTTCTAAGAAAAAAGCAACAGATTCAAAGCAGCCCTCAATCCTTGATGTGCTCTCGAAGCAAAGTCCTAAAAAAACCAAAGCCACCAAGAAGCCTGCTGCTGTCAAAAAGTCTTCTGACTCGGATGACGAAAGCGCCGTTGCGGTTAAGAGACCAGCCAAAAAGAGGAAGACCGCTCTGAGCAGTGACCAATCAGACAGCTCTGACTCTGACAGTGGCAATCTGATGGCTCGCCTCAAGGGCAAAAGCACCACTGGAAAGaaagcaaagagctgggaAGACGATGACAGCTTTCAGCTGGAAGAGAAAGTTGTGACGTCTGCAGCTCCCAGGAGCCGAGCTGCACGTACCACCAAACCTGTGACCTACACtcttgattctgattctgatgacTGTTAAATGTCTTAAAGTAGCCTGTTTGTATGAGACTCAGTTACTTAgatgttgttggttttttttttttttttagatgcttATACATGCAAAAAGACTGTTTTATGTTGGTCGTTGTTTTTAAAGTGATCAATAACAAACTAAAATTTGTGTGAACAggttttgtagtttattttgttatattattgcACATTACATTGTTCGTTGTTGCTTTTTATAcatgttgttttgtcttgtaaatattttatatgttctcTTGTTCGAAGCTCGTAATAAATTTTCAGTGACATTTGTATTGGTCTCCATTTTGAACTTGTATCTTTATATCAAAGTGGGGTTTATGCACATTGAATTTATAATATAGTATTTGTACTGTTAAATTTTACTGTATCCCTAATGGCTGTTAATTTTGAAGAGAaagatcacccaaaaataaaaattgttgctGTACACCCTGTA

Function

symbol description
top2a Predicted to enable DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity. Acts upstream of or within animal organ regeneration and chromosome segregation. Predicted to be located in nucleoplasm. Predicted to be part of DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex. Predicted to be active in nucleus. Is expressed in digestive system; head; nervous system; neural tube; and pectoral fin. Orthologous to human TOP2A (DNA topoisomerase II alpha).

NR:

description
DNA topoisomerase 2-alpha

GO:

id name namespace
GO:0006312 mitotic recombination biological_process
GO:0000819 sister chromatid segregation biological_process
GO:0030261 chromosome condensation biological_process
GO:0031100 animal organ regeneration biological_process
GO:0006200 obsolete ATP catabolic process biological_process
GO:0000712 resolution of meiotic recombination intermediates biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0006261 DNA-dependent DNA replication biological_process
GO:0006265 DNA topological change biological_process
GO:0000795 synaptonemal complex cellular_component
GO:0009295 nucleoid cellular_component
GO:0009330 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex cellular_component
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0003677 DNA binding molecular_function

KEGG:

id description
K03164 TOP2; DNA topoisomerase II

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043254134.1 True 5333 mRNA 0.45 35 3917420 3931659

Neighbor

gene id symbol gene type direction distance location
raraa raraa,rara,LOC107716487,LOC107745620,LOC107571738,LOC107660476,LOC107678286,LOC105935622 coding downstream 35637 3766347 ~ 3881783 (-)
vps35l zgc:163107,cunh16orf62,cssa28h16orf62,LOC107678404,LOC107716486,LOC107660477 coding downstream 152969 3753578 ~ 3764451 (-)
c12h10orf88 si:rp71-19m20.1,LOC107716483,LOC107598032 coding downstream 186971 3725084 ~ 3730449 (-)
LOC122355770 LOC107660482,LOC107716480,LOC107678383,LOC107745560,LOC108435041 coding downstream 377265 3497872 ~ 3540155 (-)
LOC122355769 grid1,grid1b,LOC107598047,LOC106577051,LOC106607602 coding downstream 519885 3393655 ~ 3397535 (-)
csf3a LOC107716456,LOC107598027,LOC107660487 coding upstream 31656 3963315 ~ 3966302 (-)
lrrc3ca lrrc3ca,lrrc3c,LOC107598050,LOC107716457,LOC107660473,LOC107678436 coding upstream 43101 3974760 ~ 3982557 (-)
trnal-uag_4 NA coding upstream 63432 3995091 ~ 3995185 (-)
trnal-aag_33 NA coding upstream 63592 3995251 ~ 3995332 (-)
trnal-uag_5 NA coding upstream 65092 3996751 ~ 3996830 (-)
G85389 NA non-coding downstream 196397 3615842 ~ 3721023 (-)
G85372 NA non-coding downstream 542469 3373377 ~ 3374951 (-)
G85355 NA non-coding downstream 757677 3156816 ~ 3159743 (-)
G85342 NA non-coding downstream 879836 2950836 ~ 3037584 (-)
G85257 NA non-coding downstream 970031 2919185 ~ 2947389 (-)
G85435 NA non-coding upstream 29104 3960763 ~ 3961353 (-)
G85487 NA non-coding upstream 186146 4117805 ~ 4175223 (-)
G85511 NA non-coding upstream 244331 4175990 ~ 4176266 (-)
G85515 NA non-coding upstream 251923 4183582 ~ 4188337 (-)
G85541 NA non-coding upstream 336344 4268003 ~ 4269616 (-)
G85366 NA other downstream 617732 3258531 ~ 3299688 (-)
LOC122355711 rara,LOC107700643,LOC107717720,LOC107565243,LOC107563215,LOC107719850,LOC108434941,LOC108261354,LOC107554136,LOC107737746,LOC108276117 other downstream 814105 3089629 ~ 3103315 (-)
G85232 LOC107663296,LOC107583514,LOC107733536 other downstream 1136067 2767908 ~ 2781353 (-)
jmjd1cb jmjd1c,LOC107745648,LOC107654065,LOC107695544 other downstream 1632368 2173988 ~ 2285052 (-)
ank3b ank3b,LOC107654059,LOC107695539 other downstream 1970008 1814083 ~ 1947412 (-)
kcnh6b LOC107684759,LOC107753307,LOC107573422 other upstream 285745 4217404 ~ 4230039 (-)
LOC122355775 NA other upstream 366208 4297867 ~ 4305215 (-)
trnal-uag_49 NA other upstream 413726 4345385 ~ 4345467 (-)
trnal-uag_50 NA other upstream 416039 4347698 ~ 4347779 (-)
trnal-aag_58 NA other upstream 416203 4347862 ~ 4347942 (-)

Expression


Co-expression Network