chuk (chuk,LOC107726965,LOC107601877,LOC107559325,LOC107743510)



Basic Information


Item Value
gene id chuk
gene name chuk,LOC107726965,LOC107601877,LOC107559325,LOC107743510
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_056711.1
NCBI id CM032080.1
chromosome length 25085836
location 9390222 ~ 9397047 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence


>XM_043254974.1
GTTTCGCTTTTGACTGGAGTAGCAGCTGACTGGCGTGGCCGCGGTCAACAACAGTTTTCACAACAGTGCGCCAGTCAGCGCTACTGTATCCAATCATCAATTTAGGGCAGCGAGTTTTAGCTGTTTTAATATTCAGGTGTTCTCTGGTCCTCGTTTTGTCGCGCCCGGTGTTATGAAAAGCTGACATTTGGAGGCTTGTAAGAGACTGCAGGCTAACAGTTCACATCGAGTTGTTTACGTGTAGCTAGTTAGCCAGTTAGCAAATCTGATATGCGATGCTCGTTTTAGGATGAAATGGATAGCTTTGTTGTCTCTCATGAATTAATACGCTCGATTGACAGGTCTCTCAATTTTCCACATCAGATGTGGTCGGTTCAAGCAAGTTAGAAACACAAACCGACGCAAGATGGAGAAACCTCCTTTCAGACAGAATCAGGTCTGTGGGTCATGGCTTATGAAGGAGAGGCTGGGCACAGGAGGATTTGGACATGTCTACCTGTATCAAAATCAGGAAACCTCAGAAAAGACTGCTGTGaagctctgtcgccttgaacttaatgcaaaaaacaaagacagatgGAGTCGAGAGATCCAGATTATGAAAAAgcTGAAGCACCTAAATGTGGTGACAGCAAAGGATGTGCCTGAAGAGATGATGCACATTGCCTTGAACGATTTACCGCTTTTAGCCATGGAATACTGTTCCAAGGGAGACCTTCGAAAGTTACTCAGCAAACCAGAAAATTGTTGCGGTTTAAAAGAGAGTGAGGTGTTGATGCTTCTCAATGATGTTGGTTCTGGAATCCAGTACCTCCATGAGAATAAGATAATTCACAGAGATCTCAAACCAGAGAATATTGTGCTACAAGATATCAATGGAAAGCTTGTCCACAAGATAATTGACCTTGGCTATGCCAAAGACCTAGACCAGGGGAGCCTATGTACTTCATTTGTGGGGACTTTACAATATTTGgCTCCAGAGCTGTTTGAAGGCAAGTCGTACACAGTCACTGTAGACTATTGGAGCTTTGGTACCATGATCTTTGAGTGCTGCTGTGGATTTCGACCATTTCTTCATAATCTTCAGCCTGTGCAGTGGACAAGCAAAGTGCGAAACAAAGGTCCTAAGGATATAATGGCTGTAGAAGACATGAATGGTGAAGTCCGCTTTTCTACCCGCCTTCCGTACCCCAACAATCTGAGCAGGACACTACTGGAACCTTTGGAGGGGCTGCTGCAGCTGATGCTAAAGTGGGACCCAGTACAAAGGGGAGGAGGATTGAATCCAGAAACAAAACAGCCCCACTGCTTTGCTCTTCTAGATCAAATACTGAACATGAAGgttgtGCACATCTTAAACATGACAACAACCCAGGTTCACTCATTTCTGCTTAGTCCAGATGAAGGGCTTCATTCTCTTCAACAAAAGATTGAGACTGAGACCAACATCGAACTTTTGAATCAAGAGCTTCTGCAGGAAACAGGAGTCATGTTAGATCCTAGGAAACCTGCTGCACAGTGTGTTTTAGATGGAGTAaGAGGATGGGACAGCTACATTGTATATCTGTTTGACAAGAGTTTAACCAAGTACTCAGGACCTCTAACAGCTAGAACACTTCCTGACAGTGTAAACTTTATCGTGCGGGAAACCAAAACTCAGCTCCCTCTGAGTGCTCTTAAAAAGGTTTGGGGTGAGGCTGTAAGCTACATTTGTGGCCTCAGAGATGACTACAGCCGCCTCTTCCAGGGCCAACGAGCAGCCATGTTGAGCCTCCTCCGCTACAACACCAACCTTACGAGATATAAGAACATGATGTTCTCCTTTTCGCAGCAGCTAAAAGCAAAGCTTGACTTTTTTAAGAGCAGCATACAGTACGACTTGGAGAAGTACAGTGATCAGATGCAGTACGGCATATCCTCTGAGAAGATGCTTAAAGCTTGGCAGGACAATGAAGATAAGGCCGCTGCGTTTGTACAGGTGGCAGAGATCGGCCACCTTGATGAGGAAATAATGTCTTTGCACTCAGAAATTGTTGAGCTTCAGAGAAGTCCTTACGCTCGTCGTCAAGGAGACGTCATGGAGCAACTGCAAGACAAAGCAATTGAACTCTACAGACAATTGAAGGCAAAATGCAAAATGCCAGACCCTCAGCACGGCTACAGTGACAGCTCTGAGATGGTGAAGGTCATTGTGCAGACTGTTCAGAATCAGGACCGGGTACTGAGGGATCTATATGCACACCTCAGTAAAATCCTTTTGAGTAAGCAGAAGATCATCGACCTCTTCCCTAAAATTGAGAGGACGCTGGAGGGCATTAAGGAGGCTGACAGCACTGTCATGCAGATGCAGGtcaagagacagagagagttcTGGCACTTACTGAAGATCGCCTGTgCGCAAAACACCACACGAAGCTCCGTGAGTCAGAGTGGAGAGATGCCCTCCTCACTGTCAACATGGAACCAGACTCAAGCCCAGTGCTCCTCTCGCCTGCCCATGTCCCTGCAAGTGCCACACGAGGGagaTTCAGTCAATCATTTACTTGAGGAGAACCAGCGCTATTTGAGTCAACTTACCAGTTTACTGCAAGAAACCACCGAGGAGAAATCAGAGAGCATCATGACTCAAGACTGGAGCTGGACTAAATACGAATCCCTGGTTGCTAAATCCCAACGTTTGTAGAGTCATGGTGAACTCTGTGACAGGAAGtcattcttttaaatgcatttattcatcttcacTGGATCGGGGTTGTGTTGACTTGTATGATTTGTTAATCATAAAGTAACTTGTCAGTATCTGAATTCATTTAATATCACATTTTGCAGTCTTGTAGCAACTCTCTATATTTTGaggatgcatttttaattgataCAGAACCAAGAACATGCAAACACAATTCAGGCAATGTAACAATGTAACtccagaaatgtatttatttacgtaCTTCATAGTTCTCTGTATGGGCTGATTGTACTTTCATTTTAGGtggttgagtttttttttttttttaattgaatatggTAGTTCAGCATCTGCACTTTAAAGGCTCACTGTGAATGTTTGGAAAGGTGTGAGATGGGGGAGTAAAATTGGTCATGTTCAAATAATGCACTTCAGCTTCACTTTTTCAAATCTTAAGAATTCTGTGAGGCCCCAAGTAAAGGTTTACAACAGGCAGATTGAAGGGCAGAACAATGTTGAGTATGATAAAAGCATAAATCTTTAGTCCCAGGTcccataaaaatgtgtttggtCAGACAAATACCAGCacagtcctttttttttatattttggatttggCAGCGATGGCAACAGAAATCTTTATATCAGGTATTAGTGGCTAAAAATGAATGTCATCATTCATCAGTGGGCaaattataatcataattttaattaaaacagtgaTGTTATTTCCCTTTTTACGTCACATTTGCAACCATGTTTTTGTCCAAAGATGATCAGCGTCACACGAGAGTTTGTCACAACTGTTGTGtaatattttgcttatttagtttgttttgttggaTTATTATCTGAGGATGTGTCTGACATGGGTTAAACGCATCTTATGGAAAAACACTTCGGTTTTAACGTGTTTACTGTATACATgacaaataaagtaattaaagtcATATCCATTATGTTA
>XM_043254975.1
GTTTCGCTTTTGACTGGAGTAGCAGCTGACTGGCGTGGCCGCGGTCAACAACAGTTTTCACAACAGTGCGCCAGTCAGCGCTACTGTATCCAATCATCAATTTAGGGCAGCGAGTTTTAGCTGTTTTAATATTCAGGTGTTCTCTGGTCCTCGTTTTGTCGCGCCCGGTGTTATGAAAAGCTGACATTTGGAGGCTTGTCTCTCAATTTTCCACATCAGATGTGGTCGGTTCAAGCAAGTTAGAAACACAAACCGACGCAAGATGGAGAAACCTCCTTTCAGACAGAATCAGGTCTGTGGGTCATGGCTTATGAAGGAGAGGCTGGGCACAGGAGGATTTGGACATGTCTACCTGTATCAAAATCAGGAAACCTCAGAAAAGACTGCTGTGaagctctgtcgccttgaacttaatgcaaaaaacaaagacagatgGAGTCGAGAGATCCAGATTATGAAAAAgcTGAAGCACCTAAATGTGGTGACAGCAAAGGATGTGCCTGAAGAGATGATGCACATTGCCTTGAACGATTTACCGCTTTTAGCCATGGAATACTGTTCCAAGGGAGACCTTCGAAAGTTACTCAGCAAACCAGAAAATTGTTGCGGTTTAAAAGAGAGTGAGGTGTTGATGCTTCTCAATGATGTTGGTTCTGGAATCCAGTACCTCCATGAGAATAAGATAATTCACAGAGATCTCAAACCAGAGAATATTGTGCTACAAGATATCAATGGAAAGCTTGTCCACAAGATAATTGACCTTGGCTATGCCAAAGACCTAGACCAGGGGAGCCTATGTACTTCATTTGTGGGGACTTTACAATATTTGgCTCCAGAGCTGTTTGAAGGCAAGTCGTACACAGTCACTGTAGACTATTGGAGCTTTGGTACCATGATCTTTGAGTGCTGCTGTGGATTTCGACCATTTCTTCATAATCTTCAGCCTGTGCAGTGGACAAGCAAAGTGCGAAACAAAGGTCCTAAGGATATAATGGCTGTAGAAGACATGAATGGTGAAGTCCGCTTTTCTACCCGCCTTCCGTACCCCAACAATCTGAGCAGGACACTACTGGAACCTTTGGAGGGGCTGCTGCAGCTGATGCTAAAGTGGGACCCAGTACAAAGGGGAGGAGGATTGAATCCAGAAACAAAACAGCCCCACTGCTTTGCTCTTCTAGATCAAATACTGAACATGAAGgttgtGCACATCTTAAACATGACAACAACCCAGGTTCACTCATTTCTGCTTAGTCCAGATGAAGGGCTTCATTCTCTTCAACAAAAGATTGAGACTGAGACCAACATCGAACTTTTGAATCAAGAGCTTCTGCAGGAAACAGGAGTCATGTTAGATCCTAGGAAACCTGCTGCACAGTGTGTTTTAGATGGAGTAaGAGGATGGGACAGCTACATTGTATATCTGTTTGACAAGAGTTTAACCAAGTACTCAGGACCTCTAACAGCTAGAACACTTCCTGACAGTGTAAACTTTATCGTGCGGGAAACCAAAACTCAGCTCCCTCTGAGTGCTCTTAAAAAGGTTTGGGGTGAGGCTGTAAGCTACATTTGTGGCCTCAGAGATGACTACAGCCGCCTCTTCCAGGGCCAACGAGCAGCCATGTTGAGCCTCCTCCGCTACAACACCAACCTTACGAGATATAAGAACATGATGTTCTCCTTTTCGCAGCAGCTAAAAGCAAAGCTTGACTTTTTTAAGAGCAGCATACAGTACGACTTGGAGAAGTACAGTGATCAGATGCAGTACGGCATATCCTCTGAGAAGATGCTTAAAGCTTGGCAGGACAATGAAGATAAGGCCGCTGCGTTTGTACAGGTGGCAGAGATCGGCCACCTTGATGAGGAAATAATGTCTTTGCACTCAGAAATTGTTGAGCTTCAGAGAAGTCCTTACGCTCGTCGTCAAGGAGACGTCATGGAGCAACTGCAAGACAAAGCAATTGAACTCTACAGACAATTGAAGGCAAAATGCAAAATGCCAGACCCTCAGCACGGCTACAGTGACAGCTCTGAGATGGTGAAGGTCATTGTGCAGACTGTTCAGAATCAGGACCGGGTACTGAGGGATCTATATGCACACCTCAGTAAAATCCTTTTGAGTAAGCAGAAGATCATCGACCTCTTCCCTAAAATTGAGAGGACGCTGGAGGGCATTAAGGAGGCTGACAGCACTGTCATGCAGATGCAGGtcaagagacagagagagttcTGGCACTTACTGAAGATCGCCTGTgCGCAAAACACCACACGAAGCTCCGTGAGTCAGAGTGGAGAGATGCCCTCCTCACTGTCAACATGGAACCAGACTCAAGCCCAGTGCTCCTCTCGCCTGCCCATGTCCCTGCAAGTGCCACACGAGGGagaTTCAGTCAATCATTTACTTGAGGAGAACCAGCGCTATTTGAGTCAACTTACCAGTTTACTGCAAGAAACCACCGAGGAGAAATCAGAGAGCATCATGACTCAAGACTGGAGCTGGACTAAATACGAATCCCTGGTTGCTAAATCCCAACGTTTGTAGAGTCATGGTGAACTCTGTGACAGGAAGtcattcttttaaatgcatttattcatcttcacTGGATCGGGGTTGTGTTGACTTGTATGATTTGTTAATCATAAAGTAACTTGTCAGTATCTGAATTCATTTAATATCACATTTTGCAGTCTTGTAGCAACTCTCTATATTTTGaggatgcatttttaattgataCAGAACCAAGAACATGCAAACACAATTCAGGCAATGTAACAATGTAACtccagaaatgtatttatttacgtaCTTCATAGTTCTCTGTATGGGCTGATTGTACTTTCATTTTAGGtggttgagtttttttttttttttaattgaatatggTAGTTCAGCATCTGCACTTTAAAGGCTCACTGTGAATGTTTGGAAAGGTGTGAGATGGGGGAGTAAAATTGGTCATGTTCAAATAATGCACTTCAGCTTCACTTTTTCAAATCTTAAGAATTCTGTGAGGCCCCAAGTAAAGGTTTACAACAGGCAGATTGAAGGGCAGAACAATGTTGAGTATGATAAAAGCATAAATCTTTAGTCCCAGGTcccataaaaatgtgtttggtCAGACAAATACCAGCacagtcctttttttttatattttggatttggCAGCGATGGCAACAGAAATCTTTATATCAGGTATTAGTGGCTAAAAATGAATGTCATCATTCATCAGTGGGCaaattataatcataattttaattaaaacagtgaTGTTATTTCCCTTTTTACGTCACATTTGCAACCATGTTTTTGTCCAAAGATGATCAGCGTCACACGAGAGTTTGTCACAACTGTTGTGtaatattttgcttatttagtttgttttgttggaTTATTATCTGAGGATGTGTCTGACATGGGTTAAACGCATCTTATGGAAAAACACTTCGGTTTTAACGTGTTTACTGTATACATgacaaataaagtaattaaagtcATATCCATTATGTTA

Function


symbol description
chuk Predicted to enable protein heterodimerization activity; protein homodimerization activity; and protein serine/threonine kinase activity. Predicted to contribute to IkappaB kinase activity. Acts upstream of or within several processes, including epiboly involved in gastrulation with mouth forming second; negative regulation of I-kappaB kinase/NF-kappaB signaling; and somite specification. Predicted to be located in nucleus. Predicted to be part of IkappaB kinase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including immature eye; nervous system; notochord; pectoral fin; and segmental plate. Human ortholog(s) of this gene implicated in fetal encasement syndrome and prostate cancer. Orthologous to human CHUK (component of inhibitor of nuclear factor kappa B kinase complex).

NR:

description
PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit alpha

GO:

id name namespace
GO:0001757 somite specification biological_process
GO:0007252 I-kappaB phosphorylation biological_process
GO:0071356 cellular response to tumor necrosis factor biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling biological_process
GO:0055113 epiboly involved in gastrulation with mouth forming second biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0007417 central nervous system development biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005524 ATP binding molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0046982 protein heterodimerization activity molecular_function
GO:0008384 IkappaB kinase activity molecular_function

KEGG:

id description
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha

RNA


RNA id representative length rna type GC content exon number start site end site
XM_043254974.1 True 3650 mRNA 0.43 22 9390222 9397047
XM_043254975.1 False 3506 mRNA 0.43 23 9390222 9397047

Neighbor


gene id symbol gene type direction distance location
ap3m1 LOC107743512,LOC107655430,LOC107726964,LOC107559324,LOC107601875,LOC107666495 coding upstream 47678 9338278 ~ 9342544 (+)
LOC122356812 LOC107725429 coding upstream 219969 9169279 ~ 9170253 (+)
dusp13a dusp13a,LOC107725429,LOC107666542,LOC107601810,LOC107743611,LOC107552920,LOC107671562,LOC108426746 coding upstream 220617 9166378 ~ 9169605 (+)
si:ch211-223p8.8 LOC107552909,LOC107743613,LOC107552922,LOC107667280 coding upstream 229500 9159647 ~ 9160722 (+)
col17a1b LOC107667282,LOC107743515 coding upstream 252793 9120348 ~ 9137429 (+)
LOC122356357 gsto1,LOC107601880,LOC107726961,LOC107743610,LOC107559317,LOC107655421,LOC107666511 coding downstream 442 9397489 ~ 9400354 (+)
LOC122356356 gsto2,LOC107726960,LOC107666561,LOC107559318,LOC107601879,LOC107743609 coding downstream 4940 9401987 ~ 9404636 (+)
calhm3 calhm3,LOC107726959,LOC107666391,LOC107743606,LOC107559321,LOC107578949 coding downstream 12704 9409751 ~ 9412120 (+)
calhm1 calhm1,LOC107726957,LOC107601812 coding downstream 15303 9412350 ~ 9414196 (+)
LOC122357057 LOC107726934,LOC107666357,LOC107559322,LOC107601796,LOC107743586,LOC107601813 coding downstream 17294 9414341 ~ 9416857 (+)
G92147 NA non-coding upstream 114523 9264064 ~ 9275699 (+)
G92111 NA non-coding upstream 245711 9140217 ~ 9144511 (+)
G92108 erlin1,LOC107743516,LOC107725471,LOC107666491,LOC107601865,LOC107676597 non-coding upstream 292317 9050367 ~ 9097905 (+)
G92087 slc1a4,LOC107725464,LOC107552941 non-coding upstream 424633 8929442 ~ 8965589 (+)
G92066 NA non-coding upstream 493313 8836716 ~ 8896909 (+)
G92313 NA non-coding downstream 53399 9450446 ~ 9450689 (+)
G92334 mcmbp,LOC107726945,LOC107601886,LOC107559330 non-coding downstream 82374 9479421 ~ 9479752 (+)
LOC122356835 NA non-coding downstream 173942 9570989 ~ 9583671 (+)
G92361 NA non-coding downstream 195372 9592419 ~ 9594277 (+)
G92432 NA non-coding downstream 327349 9724396 ~ 9727967 (+)
zgc:153981 zgc:153981,LOC107725455,LOC107666543,LOC107601871,LOC107671561,LOC107552921,LOC108426808 other upstream 226108 9161517 ~ 9164114 (+)
spef1 zgc:66426,LOC107601866,LOC107725472,LOC107666492,LOC107743614 other upstream 301101 9080848 ~ 9089121 (+)
fuom fuom,LOC107676595,LOC107666397,LOC107601808 other upstream 362313 9025943 ~ 9027909 (+)
sf3b5 sf3b5,LOC107601807 other upstream 650127 8739036 ~ 8740095 (+)
pcnx2 pcnxl2,LOC107725461,LOC107601842,LOC107743596,LOC107666362,LOC107676602,LOC107552953 other upstream 707170 8666267 ~ 8683052 (+)
atoh7 atoh7,LOC107726941,LOC107601814,LOC107666420,LOC107743508,LOC107655428,LOC108426756 other downstream 33131 9430178 ~ 9434605 (+)
LOC122356813 adka,LOC107743514,LOC107666490,LOC107601874,LOC107655429,LOC107725426,LOC100196663 other downstream 808066 10205113 ~ 10249725 (+)
ly6pge si:ch73-28h20.1,LOC107716297,LOC107673896,LOC107585320,LOC105890420,LOC106578825 other downstream 1019193 10416240 ~ 10420426 (+)
eif4ebp2 eif4ebp2,LOC107668794,LOC107588631,LOC107716353,LOC107564345,LOC107707337,LOC107673927 other downstream 1567808 10964855 ~ 10968914 (+)
G92772 LOC107588620,LOC107707271,LOC107707282 other downstream 1816479 11213526 ~ 11218175 (+)

Expression



Co-expression Network