calm2a (calm1,LOC107396020,LOC102778633,LOC102293206)



Basic Information


Item Value
gene id calm2a
gene name calm1,LOC107396020,LOC102778633,LOC102293206
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_056711.1
NCBI id CM032080.1
chromosome length 25085836
location 4387181 ~ 4391197 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence


>XM_043255643.1
ATGGAGAGAAAGCAGGGGGAGGAGTTTATAAGCGACCATTAAAGGCGCGTCAAGCTCTGTATGAGTGCATCCTGTTTGTTTGCCAGCTGCGGACTGTTGTTGTGTGTGGAGATACATCTGTTAAAACAGCGCGATGGCTGACCAGTTGACAGAAGAGCAGATTGCCGAATTCAAAGAGGCTTTCTCACTCTTTGACAAGGACGGCGATGGCACCATCACAACCAAAGAGCTGGGCACTGTCATGCGCTCGCTCGGACAGAATCCAACAGAGGCTGAGCTCCAAGACATGATCAACGAAGTGGATGCTGATGGAAACGGGACGATAGACTTCCCAGAGTTCCTGACCATGATGGCGAGGAAGATGAAGGACACAGACAGCGAGGAGGAGATCAGAGAAGCATTCCGTGTCTTTGATAAGGATGGGAATGGTTACATCAGTGCAGCCGAGCTGCGTCACGTCATGACAAACCTCGGAGAGAAGTTGACCGACGAGGAGGTTGATGAGATGATCAGAGAAGCAGATATTGATGGAGACGGACAGGTTAACTACGAAGAATTCGTACAGATGATGACGGCGAAATGAAGGCCTTGTACAGATCCTCTCTCTTCTATAAATAATTtgccttttttctgtttaatttatcTGTAAAACGTTAAGTCCCCTCCCCTTCCTCCTCCCGGCTGTCCAAAGGAACTGCATGTAAACTGCATAGGATCTTCAGTCCTCATGTCCCTTTCTTTTGCTGTCATCGTGTTTTTGGAGTGGCGGTGCGGTTACACGATCAGGTGCTTGTTGCCGCGAAGAGGGGGTTGtgacgtgcaaaaaaaaataaaaaatacctgACGTCACGTCTGTCTGCCCTCCTCATGCGTAGCAAGAGTGGAGACCTGCCAGCTGGTTGTCTCTTGGCAGCGACACTGGCATGGCATCAATGTAGAGGAATAACTCTGCATGGACTATGGacaaagtatattatatatatatatacattcatataatataatataatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatat

Function


symbol description
calm1 Enables several functions, including N-terminal myristoylation domain binding activity; enzyme activator activity; and enzyme binding activity. Involved in several processes, including positive regulation of hydrolase activity; regulation of calcium ion transmembrane transport; and regulation of heart contraction. Located in microtubule cytoskeleton and sarcomere. Part of calcium channel complex and catalytic complex. Implicated in catecholaminergic polymorphic ventricular tachycardia 4 and long QT syndrome 14. Biomarker of Alzheimer's disease.

NR:

description
unnamed protein product

GO:

id name namespace
GO:0022400 regulation of rhodopsin mediated signaling pathway biological_process
GO:0001975 response to amphetamine biological_process
GO:0007190 activation of adenylate cyclase activity biological_process
GO:0045087 innate immune response biological_process
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion biological_process
GO:0051412 response to corticosterone biological_process
GO:0007202 activation of phospholipase C activity biological_process
GO:0005513 detection of calcium ion biological_process
GO:0002027 regulation of heart rate biological_process
GO:0000086 G2/M transition of mitotic cell cycle biological_process
GO:0030168 platelet activation biological_process
GO:0002576 platelet degranulation biological_process
GO:0038095 Fc-epsilon receptor signaling pathway biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0035307 positive regulation of protein dephosphorylation biological_process
GO:1901841 regulation of high voltage-gated calcium channel activity biological_process
GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction biological_process
GO:0043647 inositol phosphate metabolic process biological_process
GO:0043388 positive regulation of DNA binding biological_process
GO:1901339 regulation of store-operated calcium channel activity biological_process
GO:0008543 fibroblast growth factor receptor signaling pathway biological_process
GO:0051000 positive regulation of nitric-oxide synthase activity biological_process
GO:0048011 neurotrophin TRK receptor signaling pathway biological_process
GO:0032465 regulation of cytokinesis biological_process
GO:0005980 glycogen catabolic process biological_process
GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity biological_process
GO:0032516 positive regulation of phosphoprotein phosphatase activity biological_process
GO:0016310 phosphorylation biological_process
GO:0046209 nitric oxide metabolic process biological_process
GO:0006006 glucose metabolic process biological_process
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity biological_process
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity biological_process
GO:0007173 epidermal growth factor receptor signaling pathway biological_process
GO:0034704 calcium channel complex cellular_component
GO:0030426 growth cone cellular_component
GO:0005813 centrosome cellular_component
GO:0000922 spindle pole cellular_component
GO:0005829 cytosol cellular_component
GO:0005576 extracellular region cellular_component
GO:0005876 spindle microtubule cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005654 nucleoplasm cellular_component
GO:0030017 sarcomere cellular_component
GO:0043548 phosphatidylinositol 3-kinase binding molecular_function
GO:0043274 phospholipase binding molecular_function
GO:0017022 myosin binding molecular_function
GO:0031800 type 3 metabotropic glutamate receptor binding molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0008179 adenylate cyclase binding molecular_function
GO:0030235 nitric-oxide synthase regulator activity molecular_function
GO:0019904 protein domain specific binding molecular_function
GO:0050998 nitric-oxide synthase binding molecular_function
GO:0048306 calcium-dependent protein binding molecular_function
GO:0005246 calcium channel regulator activity molecular_function
GO:0072542 protein phosphatase activator activity molecular_function
GO:0031432 titin binding molecular_function
GO:0044325 ion channel binding molecular_function
GO:0016301 kinase activity molecular_function
GO:0031996 thioesterase binding molecular_function
GO:0031997 N-terminal myristoylation domain binding molecular_function

KEGG:

id description
K02183 CALM; calmodulin

RNA


RNA id representative length rna type GC content exon number start site end site
XM_043255643.1 True 1088 mRNA 0.44 6 4387181 4391197

Neighbor


gene id symbol gene type direction distance location
LOC122356983 LOC107727362,LOC107586506,LOC107699285,LOC107678514,LOC107590018,LOC107756817 coding upstream 9351 4373214 ~ 4377830 (+)
si:ch73-105b23.6 LOC107586506,LOC107727362,LOC107699285,LOC107756817,LOC107678514 coding upstream 13628 4364023 ~ 4373553 (+)
LOC122356796 NA coding upstream 24639 4360535 ~ 4362542 (+)
plekhh2 LOC107678558,LOC107707149,LOC107699295,LOC107586497,LOC107590017,LOC107727353 coding upstream 38328 4325638 ~ 4348853 (+)
trnai-uau_4 NA coding upstream 315282 4071806 ~ 4071899 (+)
stpg4 LOC107590019,LOC107678571,LOC107708399 coding downstream 1696 4392893 ~ 4400833 (+)
mcfd2 mcfd2,LOC107727380,LOC107699287 coding downstream 47254 4438451 ~ 4441070 (+)
prkceb prkceb,LOC107727364,LOC107699301,LOC107708403,LOC108422423,LOC108263296 coding downstream 83223 4474420 ~ 4547509 (+)
epas1b LOC107727363,LOC107586486,LOC107699276,LOC107708405 coding downstream 157903 4549100 ~ 4583499 (+)
dhx57 dhx57,LOC107727356,LOC107708406,LOC107678533,LOC107699277 coding downstream 204451 4595648 ~ 4607089 (+)
LOC122357002 NA non-coding upstream 141391 4244608 ~ 4245790 (+)
LOC122356176 NA non-coding upstream 244679 4137317 ~ 4142502 (+)
G90650 NA non-coding upstream 281710 4105247 ~ 4105471 (+)
G90646 LOC107707147,LOC108422651 non-coding upstream 324402 4057260 ~ 4062779 (+)
G90579 LOC107586473,LOC107758132,LOC107666233 non-coding upstream 374065 3992508 ~ 4013116 (+)
G90659 socs5b,socs5,LOC107727375,LOC107586485,LOC107699300,LOC107708402 non-coding downstream 68442 4459639 ~ 4465868 (+)
G90700 NA non-coding downstream 79868 4471065 ~ 4471744 (+)
G90888 NA non-coding downstream 573505 4964702 ~ 4965015 (+)
G90879 LOC107733683,LOC107690158,LOC107582524,LOC107678493,LOC107708465 non-coding downstream 612213 5003410 ~ 5013662 (+)
G90905 NA non-coding downstream 644162 5035359 ~ 5036116 (+)
G90660 epcam,LOC107699293,LOC107727368,LOC107586477,LOC107707148,LOC107678540,LOC107707150,LOC108422531,LOC107723711 other upstream 33250 4182499 ~ 4353931 (+)
pkdcca pkdcca,LOC107669579,LOC107739483,LOC107718010,LOC107695038,LOC107590011,LOC107586469 other upstream 554631 3809053 ~ 3832550 (+)
prkn park2,LOC107739476,LOC107669573,LOC107696378 other upstream 673418 3620406 ~ 3713763 (+)
G90377 NA other upstream 937164 3449401 ~ 3450017 (+)
G90348 dnph1 other upstream 1106184 3277837 ~ 3280997 (+)
si:ch211-250c4.5 LOC107727386,LOC107699305,LOC107586489,LOC107708409,LOC107678597 other downstream 170451 4561648 ~ 4695842 (+)
si:ch73-49p17.1 LOC107678601,LOC107727381,LOC107589548,LOC107708422 other downstream 600956 4992153 ~ 4997991 (+)
rab11fip5a LOC107733767,LOC107690145,LOC107582533 other downstream 786521 5177718 ~ 5198404 (+)
ap5s1 ap5s1,LOC107693289,LOC107678575,LOC107718444,LOC107567857,LOC107582535,LOC107733789 other downstream 869839 5261036 ~ 5271247 (+)
lamtor3 lamtor3 other downstream 1560020 5951217 ~ 5952517 (+)

Expression



Co-expression Network