l2hgdh (l2hgdh,LOC107682613,LOC107736610,LOC107705441,LOC107654945)


Basic Information

Item Value
gene id l2hgdh
gene name l2hgdh,LOC107682613,LOC107736610,LOC107705441,LOC107654945
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056711.1
NCBI id CM032080.1
chromosome length 25085836
location 14227198 ~ 14232322 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043256282.1
TCCTAAACGCTAACGTTACGGAGAGGAGATACCTTTACTCGAGAGTGAGCCTTACCGGGTCGGCGGCGAGCATTATGATTACACGGTTGTAATAAGCAAATAAGTTAGGAAAAGCGACGACGTAATTCGTGGAATAATGATACGAACTTTCGGTGCTGGATCTGTGTGCGCGCGCTTACTGACACAAGGATCAAAGTATGCAACGTGCAGAGCTGCACACCACAGCGGCTCATTTGATGTGGCTGTTATTGGTGGAGGGATTGTTGGACTGGCCTCTGCCAGAGAGCTGATCCTCAGGCACCCAAACATCACCTTTACCCTGctggagaaagaaaaggagcTTTCTCTCCATCAGACAGGTCACAACAGCGGTGTGATCCACTCTGGGATATACTACACACCAGGCTCTCTGAAGGCTCGGCTTTGTGTTCGTGGAGCCATGCTAACATATCAGTACTGCCAGAAGAAAGGTGTGCCTTATAAGAAATGTGGCAAGCTTATCGTAGCagtggagagagaggagatccCCCGTCTGAAAGCTCTATATGAACGCGGTCAGGTGAACAATGTACAAGATCTCCGTCTGATTGACGCCAAGGCCATCCGAGAGAAAGAGCCGTACTGCAGGGGCATCATGGCATTAGACTCTCCTAACACAGGAATAGTTGACTGGCGGTTAGTAGCTCTGACCTACGGGAAGGACTTCCAGGAAGCAGGTGGCACCGTGATAACTGACTTTGAAGCATCTGACATTAAGGTGGCGGCAGAAAGCCCAGCTGGGAGTGCCGAAGGGCTGAAATATCCCATCGTCATCAAAAGCTCACAGggGATGGAGGTGAGGTGTCGGTTTGTGTTGACCTGCGGAGGCCTTTACTCTGATCGGCTGTCTGAGATATCTGGCTGCAGTCCAGAGCCCCGTGTTGTTCCCTTCAGAGGAGATTACCTGGTGCTTAAACCAGAGAAAAACTACCTGGTCAGGGGCAACATTTACCCTGTGCCAAACCCACGGTTCCCATTTCTTGGATTCCATTTCACTCCTCGTATGGACGGTAGTATCTGGCTTGGCCCAAACGCTGTGTTGGCTTTTAAACGAGAGGGCTATAAACTCTTTGACTTCGACACGCAAGACTTTGTTAATGCAGTCTCATACAGgggTCTGCAGAGGCTGGTAATGAAGAACATTGTGTATGGAATGGGAGAAATATATAGAGGTGTGTTTACAAGTGCTCAGGTAAAGAACCTGCAGAAGTTCATACCTGAACTGAGCCCCAGCGATGTCCTCAGGGGACCTTCGGGTGTGCGCGCGCAGGCTTTGGATGCTGAAGGAAACCTGGTGGATGATTTCGTGTTTGACAGTGGGAAGGGAGAGCTGGGCAGCCGGATTCTGCATGTGCGCAACGCCCCGTCACCCGCTGCGAGCTCCTCCCTGGCCATCGCTGAAATGATCGCTGATGAACTGGAGAAAAGATTTCAACTGTAGACGTACCTCAGACGATGCTGCCATAACCTTTCTCACTCTAGTGCTTCAATTCAGAAGAtgaaataattatgtaataagTTTTACTTTTATACTGCTGAGGGACAGTAATAATGTAAAGAGATTTCTGGTGCTCCTTTCTAATGTATATTCTGAAAATTGTGCAGATTTAAGGGAATGTTGGGTAACTGTTGCTATGTCTTTGTAAACCTGGTGATTTATGAGGAAAAATAACTgccttaaaaacataaaaaaggcaGTTGCTTCTTAAGAGAATGCATTCACTCCATAcctgcatttataaaaataaagcatgacaattttt

Function

symbol description
l2hgdh Predicted to enable (S)-2-hydroxy-acid oxidase activity and 2-hydroxyglutarate dehydrogenase activity. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in 2-hydroxyglutaric aciduria; L-2-hydroxyglutaric aciduria; cerebellar ataxia; hereditary spastic paraplegia; and visual epilepsy. Orthologous to human L2HGDH (L-2-hydroxyglutarate dehydrogenase).

NR:

description
L-2-hydroxyglutarate dehydrogenase, mitochondrial

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0016491 oxidoreductase activity molecular_function

KEGG:

id description
K00109 L2HGDH; 2-hydroxyglutarate dehydrogenase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043256282.1 True 1802 mRNA 0.48 10 14227198 14232322

Neighbor

gene id symbol gene type direction distance location
sos2 LOC107654947,LOC107602966,LOC107736529,LOC107683816,LOC107553213 coding downstream 3072 14209375 ~ 14224126 (-)
cdkn3 cdkn3 coding downstream 26419 14192514 ~ 14200779 (-)
lgals3a lgals3a,LOC107736502,LOC107683071,LOC107705436,LOC107602963,LOC107553209,LOC107654953 coding downstream 42705 14178150 ~ 14184493 (-)
LOC122356234 synj2bp,LOC107705435,LOC107654920,LOC107736856,LOC107553210,LOC107580248 coding downstream 50324 14172637 ~ 14176874 (-)
LOC122356233 LOC107705434,LOC794838,LOC107553207,LOC107683381,LOC107654921,LOC107602927 coding downstream 55343 14164734 ~ 14171855 (-)
cdkl1 cdkl1,LOC107705442,LOC107736652,LOC107553215,LOC107602970,LOC107683176,LOC105890986 coding upstream 3778 14236100 ~ 14243270 (-)
map4k5 map4k5,LOC107602968,LOC107705444,LOC107736580 coding upstream 11080 14243402 ~ 14267479 (-)
sav1 sav1,LOC107705447,LOC107654943,LOC107736858,LOC107602931,LOC107682971,LOC107553191 coding upstream 45074 14277396 ~ 14285372 (-)
nin LOC107602976,LOC107654941,LOC107705448,LOC107736676 coding upstream 53447 14285769 ~ 14305538 (-)
pygl pygl,LOC107736703,LOC107683467,LOC107602977,LOC107553219,LOC106611459 coding upstream 74708 14307030 ~ 14314868 (-)
G93905 NA non-coding downstream 37294 14187539 ~ 14189904 (-)
G93879 NA non-coding downstream 296904 13761046 ~ 13930294 (-)
G93855 NA non-coding downstream 538572 13685947 ~ 13688626 (-)
G93591 LOC107705361,LOC107654976,LOC107602941 non-coding downstream 560938 13665809 ~ 13666260 (-)
G93588 LOC107654976,LOC107553194,LOC107602941 non-coding downstream 563287 13661750 ~ 13663911 (-)
G94003 NA non-coding upstream 640110 14872432 ~ 14873014 (-)
G94016 NA non-coding upstream 748674 14980996 ~ 14995700 (-)
G94063 NA non-coding upstream 1047085 15279407 ~ 15284055 (-)
G94132 NA non-coding upstream 1372365 15604687 ~ 15605713 (-)
G94145 NA non-coding upstream 1407953 15640275 ~ 15640633 (-)
srsf5a srsf5,srsf5a,LOC107683426,LOC107602962,LOC107654954,LOC108411053 other downstream 62784 14160323 ~ 14164414 (-)
LOC122356235 LOC107705430,LOC107683441,LOC107553204,LOC107602960,LOC107654922 other downstream 144408 14079532 ~ 14082790 (-)
G93875 LOC107680680,LOC107739875,LOC107576479,LOC107553198,LOC107705377,LOC107654967 other downstream 315361 13910339 ~ 13911837 (-)
LOC122356386 LOC107654968,LOC107705418,LOC107602947,LOC107680458,LOC107739873 other downstream 322496 13898258 ~ 13904702 (-)
map3k4 map3k4,LOC107654971,LOC107705416,LOC107679660,LOC107739870 other downstream 508884 13693026 ~ 13718314 (-)
lmbrd1 lmbrd1,LOC107747273,LOC107736841,LOC107664263 other upstream 792510 15024832 ~ 15099233 (-)
col9a1b col9a1b,LOC107736853,LOC107664283,LOC107747286,LOC107665560,LOC107747272,LOC107736861,LOC108429279,LOC107564679 other upstream 995010 15227332 ~ 15253357 (-)
G94128 NA other upstream 1332295 15564617 ~ 15583917 (-)
G94147 NA other upstream 1409709 15642031 ~ 15642503 (-)
zgc:123010 LOC107601052,LOC107747265,LOC107719217,LOC107665557,LOC107702739 other upstream 1453948 15686270 ~ 15720816 (-)

Expression


Co-expression Network