six3a (six3,six3a,LOC107733790,LOC107585256,LOC107711438,LOC107666567)


Basic Information

Item Value
gene id six3a
gene name six3,six3a,LOC107733790,LOC107585256,LOC107711438,LOC107666567
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056711.1
NCBI id CM032080.1
chromosome length 25085836
location 6704087 ~ 6707392 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043256328.1
CTCACGGTGGATTTAGGGGGAGATATTATGAGGCTGGTGTCATTAGGCGATAGCTATTGAATCATTCAATCTGAATTCGTCGTTCTTTTTTCCTTCGCAAATTTCATTCTCTCTCAGGTCATTTCCATGGTTTTCAGATCGCCTTTAGAGCTTTATCCCTCTCATTTCTTTCTGCCAAACTTTGCTGATCGCCCTTTGCTCTTGGCGAGCAGTGCGCCCAGCACCAGGTCTCCCGAAGACTTGTCAATGTTTCAGCTACCGACCCTAAACTTCTCTCCGGAGCAAGTGGCGAGCGTCTGCGAGACGCTGGAGGAGACCGGGGACATCGAGCGGCTGGGTCGCTTCCTGTGGTCGCTTCCAGTGGCACCGGGTGCTTGCGAGGCGATCAACAAGCATGAATCCATCCTGCGCGCCCGGGCTGTTGTTGCCTTTCACACCGGCAATTTTCGCGATCTCTATCACATTCTGGAGAACCACAAGTTTACCAAGGACTCGCACGGCAAACTGCAAGCGATGTGGCTCGAGGCTCACTATCAGGAGGCCGAGAAATTACGCGGGCGTCCCCTAGGACCGGTTGATAAGTACAGGGTGCGAAAGAAGTTTCCCCTGCCTAGAACCATCTGGGACGGCGAGCAGAAGACGCATTGTTTCAAAGAGCGAACGCGGAGTCTGTTACGCGAGTGGTACCTTCAGGACCCCTACCCAAACCCCAGCAAGAAAAGGGAACTGGCTCAAGCCACTGGACTCACTCCTACACAGGTCGGAAATTGGTTTAAAAACCGGAGACAACGAGACAGGGCAGCGGCAGCAAAAAACAGGCTCCAGCATCAAGCAATAGGGCAGAACGGCATGCGGTCCCTCTCGGAGTCCGGCTGCACCCCACGCAGCTCGGCGGAGTCGCCGTCGACCGCGGCCAGTCCCACGACCAGCGTCTCGAGCATGACAGAGCGAGTCGACACGGGCACGTCGATCCTTTCAGTAACGTCAAGTGACTCGGAATGCGACGTATGATACGcaaaagagaaatatatgcAGGAAAAAGGACCTGAACGAACTTGATTAATTATCGGGGAAGATGAAAAAGGACCAAttgatattactattataaaaagaaaaacataaaagcacGTCTTTTTTCAAGCGCTTTCAATGGACCCCACACCTTTCCCTCTCCTCACCACCACCACCCCATCACttgcatgatatatatatatatatatctaaatatatattttttctttttttgtatatggGGAAATGCCCCACGTTTATTATGTCTACCAGGACCACCGCGAAGAGGGAATTACCAGAAACCGGTGTCCATcgcctttttttctgttttagtccGCGTGACGACGAGCAGCCAGGATGCAATCCTCTTTTCCTTTATGTTCATCAGACAATCATTTGAGTCGTAAGCACCTTTTTACTACACTTCTGTCACTGCCTGTGTGGGGTACTGGTCAAATGTGGAACTGAATCGTTATGACTgtatcagatttttatttttatttcgagattttatattgaattatgTATATCTTAAATAATGCGATCATTCTCCCAGTCTGTAATATATGTGTAGAAATAAGTCTGTAAATAATATTGCTATACCCATTCTCTTTTCTATCCCTGTTCACTTTTCTTGGCTTGGTGTCCCTACATAAAACTATTCGTCAAAACGTAAATATTAAGTGCTCTAGGCGGttttgtttccatgttttacGCCATGAAAAGAACGCTAGTGACCATGAAGCATCAGTCGAGATTAATGCAAAAGACTAAATATTGGATATCGTCATCGGCTGACCAAGTCTATTTCATGTTTCCAGTCCAGCGCTTATAATTCAATGTTACTTTCTTGCGTGTTTCTGTTAATGTATACGTTTCTAAACTGAAAATACAGTATTCAATTTTGTTATAAAA

Function

symbol description
six3a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within brain development and optic nerve morphogenesis. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including anterior neural keel; central nervous system; eye; neural plate; and optic vesicle. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 2. Orthologous to human SIX3 (SIX homeobox 3).
six3 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and transcription corepressor binding activity. Involved in eye development; forebrain dorsal/ventral pattern formation; and negative regulation of transcription, DNA-templated. Predicted to be part of chromatin and transcription regulator complex. Predicted to be active in nucleus. Implicated in holoprosencephaly and holoprosencephaly 2.

NR:

description
PREDICTED: homeobox protein SIX3

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0007420 brain development biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K19473 SIX3_6, OPTIX; homeobox protein SIX3/6

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043256328.1 True 1926 mRNA 0.46 2 6704087 6707392

Neighbor

gene id symbol gene type direction distance location
camkmt si:ch73-54n14.2,camkmt,LOC107602502,LOC107585255,LOC107733780,LOC107698723,LOC107666367 coding upstream 49854 6561232 ~ 6654233 (+)
slc3a1 slc3a1,LOC107747531,LOC107666489,LOC107698747,LOC107733775 coding upstream 150761 6545507 ~ 6553326 (+)
ppm1ba ppm1ba,LOC107733761,LOC107585253,LOC107747533,LOC107666482,LOC107602505,LOC107698745 coding upstream 160858 6516883 ~ 6543229 (+)
abcg8 abcg8,LOC107666472 coding upstream 252579 6444614 ~ 6451508 (+)
cep170aa LOC107747537,LOC107666471,LOC107587839,LOC107733772 coding upstream 274700 6396742 ~ 6429387 (+)
LOC122356727 LOC107585260,LOC107585259,LOC107733721,LOC107733720,LOC107698744 coding downstream 133205 6840597 ~ 6843540 (+)
LOC122356807 LOC107585259,LOC107733721,LOC107733720,LOC107585260,LOC107683040 coding downstream 137340 6844732 ~ 6848243 (+)
tm9sf3 tm9sf3,LOC107711435,LOC107698740,LOC107666468,LOC102778527 coding downstream 142143 6849535 ~ 6860874 (+)
sfxn4 sfxn4,LOC107711434,LOC107733723 coding downstream 156754 6864146 ~ 6867334 (+)
eif3s10 eif3s10,eif3a,LOC107666466 coding downstream 165842 6873234 ~ 6885961 (+)
G91492 NA non-coding upstream 4918 6693662 ~ 6699169 (+)
G91343 NA non-coding upstream 251011 6452744 ~ 6453076 (+)
G91324 NA non-coding upstream 333559 6370210 ~ 6370528 (+)
G91250 gabrb1,LOC106937613 non-coding upstream 702025 5998442 ~ 6002062 (+)
G91172 NA non-coding upstream 747489 5954891 ~ 5956598 (+)
LOC122356144 NA non-coding downstream 15888 6723280 ~ 6755554 (+)
G91529 NA non-coding downstream 107618 6815010 ~ 6861516 (+)
G91545 NA non-coding downstream 235175 6942567 ~ 6942795 (+)
G91594 NA non-coding downstream 339549 7046941 ~ 7047247 (+)
G91673 NA non-coding downstream 1102479 7809871 ~ 7810104 (+)
akt3a akt3a,akt3,LOC107587843,LOC107666464,LOC107585250,LOC107666430,LOC103024575,LOC108422057,LOC106589689 other upstream 346070 6254603 ~ 6358017 (+)
commd8 commd8,LOC107666485,LOC107556927,LOC107733703,LOC107585230 other upstream 717108 5982518 ~ 5986979 (+)
lamtor3 lamtor3 other upstream 751570 5951217 ~ 5952517 (+)
ap5s1 ap5s1,LOC107693289,LOC107678575,LOC107718444,LOC107567857,LOC107582535,LOC107733789 other upstream 1432840 5261036 ~ 5271247 (+)
rab11fip5a LOC107733767,LOC107690145,LOC107582533 other upstream 1505683 5177718 ~ 5198404 (+)
LOC122356719 LOC107585299,LOC107733725,LOC107698728,LOC107711427,LOC107666365,LOC107711426,LOC107585285,LOC107733707 other downstream 385752 7093144 ~ 7147218 (+)
sh2d4ba sh2d4ba,LOC107713884,LOC107666399,LOC107565924,LOC107743625,LOC107696870 other downstream 1064168 7771560 ~ 7787307 (+)
chchd1 LOC107713887,LOC107565922,LOC107743624,LOC107696882,LOC107666381,LOC107555316 other downstream 1128788 7836180 ~ 7838945 (+)
zswim8 LOC107666425,LOC107565928,LOC107713895,LOC107743573 other downstream 1151306 7858698 ~ 7886690 (+)
G91833 slc37a1 other downstream 1599094 8306486 ~ 8310824 (+)

Expression


Co-expression Network