XLOC_006681 (hif1an)


Basic Information

Item Value
gene id XLOC_006681
gene name hif1an
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 29952633 ~ 29980215 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012882
GTTATGAGTAGGAAAACACAGCCAGTGTTTCTGTTTTCACGCTGCTTGTATGACTGCGCGGGTCGCTCGTCTGTTCGTGCCTCGGCGGGGTGTGTGAAGCCCAGGAGCGGTTCTCGAGCTCGCCGGCTCCCCTTTCAGACCATCGGCCTCTCGAGGTTTCTTTGTGCTGCCCCAGTGATCCTCTGGCGGACTCGGAGGACATGGCGGAGACCGACGGAGCCGCCGCCTTCACGGAGCTGCGCGACCCGGACTGGGATGAGTCGCAGCTTCGACAGTATACTTTTCCAACCCGACAAATACCGCGACTGTCCCATACGGATCCGCGTGCCGAGGTGCTCATCAATAACGAGGAGCCTGTTGTACTGACAGACACCAGTTTAGTATATCCAGCTCTAAAATGGGACATACCCTACTTGCAGGAGAATATCGGAAATGGGGACTTCTCTGTTTACATAGCAGAAAATCACAAATTCTTATATTACGACGAGAAGAAAATGGTTAACTTTCAAGACTTTGTGCCTAAATCTCGTCGAATAGAGATGAAGTTTTCTGAGTTTGTGGACAAGATGCATCAAACAGAAGAGCAAGGCGGGAAAGGAAGAGTGTACTTGCAACAGACTCTGAATGATACGGTAGGGCGGAAAATTGTGGTGGATTTCCTTGGATTCAATTGGAACTGGATTAACAAACAGCAAGCTAAACGAAACTGGGGACCGCTGACCTCTAATCTGCTGCTCATAGGCATGGAAGGCAATGTAACACCAGCACACTATGACGAGCAACAGAATTTCTTTGCACaaatcaaaggacataaaagatGCATCCTCTTTCCGCCGGATCAGTTTGACTGCCTCTATCCTTATCCAGTCCATCATCCATGTGACAGACAGAGTCAGGTTGATTTTGAAAATCCTGACTATGACAAGTTTCCTAATTTCAAAAATGCTGTTGGGTATGAGGCTGTCGTGGGACCCGGAGATGTGCTGTACATCCCCATGTATTGGTGGCATCACATTGAGTCCCTTTTAAATGGAGGAGAGACCATCACAGTCAACTTCTGGTACAAGGGGGCTCCCACTCCAAAGAGGATAGAGTATCCTCTGAAAGCCCATCAGAAGGTGGCCATAATGAGGAATATAGAGAAGATGTTGGGAGAGGCCTTGGGGGACCCACATGAGGTCGGTCCGTTGCTGAACATGATGATCAAGGGCAGATATGATCATGGACTGAGTTAATAGCCTGTACTGAAGCTTCTTTAGTGTGCTGCTACAACAgtctgtttatgtgtgtatgagagagagaatgtgaatgGGAGTATGTGCTTGTGTGTACATTCAGACTGTTGAAATGCCAGTGCATGGCAGTATTTTGGCAGTATAAAGACTTTCGCCTTTGTCTGCATTCACTTACTGGACCCATTGTCGTTAGTTCTGTGTTGGTGTAAGGAAAAATACCACTGTTGAGGAATCCTGATTTGATCTCTCCTTAACAAGCGTAACTAAATTCAGCATTATGtgctaaaaaagtaataaaaaatagacGAATGCATTAGCAGAGGCCTCTAAAGCACTTTTACACCACCCAGAGCGCCTGTTGTCAGGTTTTGTCCCATGTTGGGAAAAAGAAGGTGCCATATGTCTTGATTAAAACTCCTGTGGATTTGAGTCCGTACAGTGAATTCTGGCTGAGCGCCTCAAGCACATCCACAACGGAGGATGATTTACAACTTGAAACCTACCATTGACGGTTTGAACCGGTTCGTACTGTCATTGTTAATGGTgttttttgtgtttgcttttgactctcatgatgatgatgatgatgatgtttctgTTATAGGATAGAAGTAACGCAGAATACAACAGTTAAATCACAATGCGTTTTTAAACTGAAGGGATTTCTTTCCTTTTGCAGCCGACTCACTGAATTAAAGTTTGCAtttgtttatgcatttttaatgatattttcccttctttttgtttttttagccaTGTGTACATTGAAGCAAATGTTTTAGTttcttgatattttatttttcagtgtaaCGTTATATGGTACCATTTCAGTAAGGATTGTAATTCAGAACAAACTACACTTGCCAAGTGTTAACTGTCTCCATGAATTGTAAGgaaataaaagcttttgaatGGTTTGATCTAA
>TCONS_00012883
TCAGGTTGATTTTGAAAATCCTGACTATGACAAGTTTCCTAATTTCAAAAATGCTGTTGGGTATGAGGCTGTCGTGGGACCCGGAGATGTGCTGTACATCCCCATGTATTGGTGGCATCACATTGAGTCCCTTTTAAATGGAGGAGAGACCATCACAGTCAACTTCTGGTACAAGGTATGCTTTATCTCACTCATGCACTTTGGTGTCTGTATACATGATACATCTGTGCACAAATCAACCATTGTTGCTCCAAACATTTCCAGGGGGCTCCCACTCCAAAGAGGATAGAGTATCCTCTGAAAGCCCATCAGAAGGTGGCCATAATGAGGAATATAGAGAAGATGTTGGGAGAGGCCTTGGGGGACCCACATGAGGTCGGTCCGTTGCTGAACATGATGATCAAGGGCAGATATGATCATGGACTGAGTTAATAGCCTGTACTGAAGCTTCTTTAGTGTGCTGCTACAACAgtctgtttatgtgtgtatgagagagagaatgtgaatgGGAGTATGTGCT

Function

symbol description
hif1an Predicted to enable several functions, including 2-oxoglutarate-dependent dioxygenase activity; ankyrin repeat binding activity; and transition metal ion binding activity. Acts upstream of or within negative regulation of vasculature development and regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alar plate midbrain region; central nervous system; immature eye; midbrain hindbrain boundary neural rod; and midbrain neural keel. Orthologous to human HIF1AN (hypoxia inducible factor 1 subunit alpha inhibitor).

GO:

id name namespace
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway biological_process
GO:0045746 negative regulation of Notch signaling pathway biological_process
GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia biological_process
GO:1901343 negative regulation of vasculature development biological_process
GO:0036138 peptidyl-histidine hydroxylation biological_process
GO:0042264 peptidyl-aspartic acid hydroxylation biological_process
GO:0042265 peptidyl-asparagine hydroxylation biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0048471 perinuclear region of cytoplasm cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0071532 ankyrin repeat binding molecular_function
GO:0016706 2-oxoglutarate-dependent dioxygenase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0008198 ferrous iron binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0051213 dioxygenase activity molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0036139 peptidyl-histidine dioxygenase activity molecular_function
GO:0036140 peptidyl-asparagine 3-dioxygenase activity molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0031406 carboxylic acid binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030826-19 Predicted to enable several functions, including 2-oxoglutarate-dependent dioxygenase activity; ankyrin repeat binding activity; and transition metal ion binding activity. Acts upstream of or within negative regulation of vasculature development and regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alar plate midbrain region; central nervous system; immature eye; midbrain hindbrain boundary neural rod; and midbrain neural keel. Orthologous to human HIF1AN (hypoxia inducible factor 1 subunit alpha inhibitor).

Ensembl:

ensembl_id ENSDARG00000031915

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012882 False 2160 mRNA 0.44 8 29952633 29980215
TCONS_00012883 True 520 lncRNA 0.45 4 29953470 29965784

Neighbor

gene id symbol gene type direction distance location
XLOC_006680 NA coding downstream 9671 29937395 ~ 29942962 (-)
XLOC_006679 NA coding downstream 149624 29709345 ~ 29803009 (-)
XLOC_006678 NA coding downstream 250692 29506613 ~ 29701941 (-)
XLOC_006677 cdhr1a coding downstream 446687 29480010 ~ 29505946 (-)
XLOC_006676 rgra coding downstream 496774 29446226 ~ 29455859 (-)
XLOC_006682 NA coding upstream 4662 29984877 ~ 29985502 (-)
XLOC_006683 wnt8b coding upstream 10875 29991090 ~ 30006260 (-)
XLOC_006684 scdb coding upstream 27339 30007554 ~ 30028103 (-)
XLOC_006685 trmt2b coding upstream 52821 30033036 ~ 30034754 (-)
XLOC_006686 tysnd1 coding upstream 155460 30135675 ~ 30143127 (-)
XLOC_006471 BX537274.2 misc downstream 19687728 10264741 ~ 10264905 (-)
XLOC_006338 rn7sk misc downstream 29126408 825904 ~ 826225 (-)
XLOC_006672 NA non-coding downstream 722698 29224992 ~ 29229935 (-)
XLOC_006671 NA non-coding downstream 1102739 28827293 ~ 28849894 (-)
XLOC_006689 NA non-coding upstream 265458 30245673 ~ 30250564 (-)
XLOC_006690 NA non-coding upstream 569194 30549409 ~ 30551509 (-)
XLOC_006691 NA non-coding upstream 588352 30568567 ~ 30571143 (-)
XLOC_006693 CT025887.1 non-coding upstream 651890 30632105 ~ 30632219 (-)

Expression


Co-expression Network