Item | Value |
---|---|
gene id | vegfaa |
gene name | vegfa,vegfaa,LOC107703930,LOC107559057,LOC107725277,LOC107688978,LOC106605015 |
gene type | misc |
species | tiger barb (Puntius tetrazona) |
category of species | ornamental fish |
Item | Value |
---|---|
chromosome id | NC_056714.1 |
NCBI id | CM032083.1 |
chromosome length | 28146790 |
location | 5232211 ~ 5245558 (-) |
genome version | ASM1883169v1_2021_tiger_barb_Genome |
symbol | description |
---|---|
vegfaa | Enables growth factor activity. Acts upstream of or within several processes, including animal organ development; circulatory system development; and regulation of vasculature development. Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular space. Is expressed in several structures, including cardiovascular system; mesoderm; nervous system; podocyte; and trunk. Used to study proteinuria. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and reproductive organ cancer (multiple). Orthologous to human VEGFA (vascular endothelial growth factor A). |
vegfa | Enables several functions, including fibronectin binding activity; heparin binding activity; and signaling receptor binding activity. Involved in several processes, including positive regulation of cell migration; positive regulation of intracellular signal transduction; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including branching involved in blood vessel morphogenesis; positive regulation of endothelial cell proliferation; and regulation of nitric oxide mediated signal transduction. Located in several cellular components, including adherens junction; cell surface; and secretory granule. Implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); hypertension (multiple); and reproductive organ cancer (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); inflammatory bowel disease (multiple); and respiratory system cancer (multiple). |
description |
---|
PREDICTED: vascular endothelial growth factor A-A-like isoform X1 |
id | name | namespace |
---|---|---|
GO:0030097 | hemopoiesis | biological_process |
GO:0007202 | activation of phospholipase C activity | biological_process |
GO:0048793 | pronephros development | biological_process |
GO:0002043 | blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological_process |
GO:0051781 | positive regulation of cell division | biological_process |
GO:0031334 | positive regulation of protein-containing complex assembly | biological_process |
GO:0048844 | artery morphogenesis | biological_process |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | biological_process |
GO:0001569 | branching involved in blood vessel morphogenesis | biological_process |
GO:0001570 | vasculogenesis | biological_process |
GO:0048010 | vascular endothelial growth factor receptor signaling pathway | biological_process |
GO:0008016 | regulation of heart contraction | biological_process |
GO:0003262 | endocardial progenitor cell migration to the midline involved in heart field formation | biological_process |
GO:0051894 | positive regulation of focal adhesion assembly | biological_process |
GO:0030878 | thyroid gland development | biological_process |
GO:0008045 | motor neuron axon guidance | biological_process |
GO:0043491 | protein kinase B signaling | biological_process |
GO:0001938 | positive regulation of endothelial cell proliferation | biological_process |
GO:0035477 | regulation of angioblast cell migration involved in selective angioblast sprouting | biological_process |
GO:0035479 | angioblast cell migration from lateral mesoderm to midline | biological_process |
GO:0005576 | extracellular region | cellular_component |
GO:0005622 | intracellular anatomical structure | cellular_component |
GO:0016020 | membrane | cellular_component |
GO:0008201 | heparin binding | molecular_function |
GO:0008083 | growth factor activity | molecular_function |
RNA id | representative | length | rna type | GC content | exon number | start site | end site |
---|---|---|---|---|---|---|---|
XM_043260760.1 | False | 3358 | mRNA | 0.41 | 7 | 5232211 | 5245434 |
XM_043260761.1 | False | 2247 | mRNA | 0.44 | 6 | 5235903 | 5245461 |
XM_043260762.1 | False | 3334 | mRNA | 0.41 | 7 | 5232211 | 5245558 |
XM_043260763.1 | False | 3189 | mRNA | 0.41 | 6 | 5232211 | 5245397 |
XR_006252796.1 | False | 1463 | transcript | 0.48 | 7 | 5235646 | 5245460 |
XR_006252797.1 | True | 3499 | transcript | 0.42 | 7 | 5232211 | 5245461 |
gene id | symbol | gene type | direction | distance | location |
---|---|---|---|---|---|
rrp15 | rrp15,LOC107598955,LOC107737032,LOC107703929,LOC107689025 | coding | downstream | 55399 | 5173650 ~ 5176812 (-) |
tgfb2 | tgfb2,LOC107598937,LOC106584161 | coding | downstream | 61581 | 5138694 ~ 5170630 (-) |
lyplal1 | lyplal1,LOC797125 | coding | downstream | 136616 | 5090511 ~ 5095595 (-) |
adcy3a | adcy3,adcy3a,LOC107688975,LOC107703925 | coding | downstream | 185328 | 5027170 ~ 5046883 (-) |
wdr26a | LOC107598934,LOC107756916,LOC107562420,LOC107688974,LOC107732721,LOC108270098 | coding | downstream | 206887 | 5012577 ~ 5025324 (-) |
ppp1r8b | ppp1r8b,ppp1r8,LOC107564517,LOC107689150,LOC107688979,LOC107713931 | coding | upstream | 110429 | 5355987 ~ 5360418 (-) |
LOC122361376 | NA | coding | upstream | 113952 | 5359510 ~ 5359679 (-) |
rpa2 | rpa2,LOC107713930 | coding | upstream | 121774 | 5367332 ~ 5379962 (-) |
tpbgb | LOC107688980,LOC107725281,LOC107713928,LOC107713927,LOC107689178,LOC107559023 | coding | upstream | 172915 | 5418473 ~ 5420640 (-) |
bckdhb | bckdhb,LOC107688983,LOC107689156,LOC107559046,LOC107569448 | coding | upstream | 263059 | 5508617 ~ 5559896 (-) |
LOC122359853 | NA | non-coding | downstream | 24792 | 5198791 ~ 5207419 (-) |
G109907 | NA | non-coding | downstream | 40861 | 5190781 ~ 5191350 (-) |
G109906 | NA | non-coding | downstream | 41506 | 5190350 ~ 5190705 (-) |
G109891 | NA | non-coding | downstream | 54676 | 5177331 ~ 5177535 (-) |
G109887 | NA | non-coding | downstream | 142907 | 5088901 ~ 5089304 (-) |
G109914 | NA | non-coding | upstream | 1680 | 5247238 ~ 5321296 (-) |
G109942 | cyp4t8,LOC107559042,LOC107703932 | non-coding | upstream | 100847 | 5346405 ~ 5347559 (-) |
G109953 | NA | non-coding | upstream | 150572 | 5396130 ~ 5396354 (-) |
G109956 | NA | non-coding | upstream | 151739 | 5397297 ~ 5397517 (-) |
G109944 | NA | non-coding | upstream | 190274 | 5435832 ~ 5437067 (-) |
G109724 | LOC107084717,LOC106511825 | other | downstream | 1136707 | 4094757 ~ 4095504 (-) |
G109600 | NA | other | downstream | 2102232 | 3113842 ~ 3129979 (-) |
prdm1a | prdm1,prdm1a,LOC107714407,LOC107697283,LOC107551748,LOC107661008,LOC107581686 | other | downstream | 3268050 | 1741120 ~ 1964161 (-) |
G109287 | NA | other | downstream | 4349459 | 882459 ~ 882752 (-) |
G109275 | NA | other | downstream | 4599314 | 632465 ~ 632897 (-) |
si:dkey-283b15.2 | si:dkey-283b15.2,si:dkey-14o18.2,LOC107688992,LOC107559040,LOC107558638,LOC108410647 | other | upstream | 537109 | 5782667 ~ 5790534 (-) |
ndufa3 | ndufa3,LOC107558639,LOC107713918,LOC107559056,LOC107726249 | other | upstream | 571482 | 5817040 ~ 5818618 (-) |
LOC122359839 | LOC107689176,LOC107726242,LOC107689019,LOC107559018,LOC107559017,LOC107558630,LOC107713911 | other | upstream | 657019 | 5902577 ~ 6184133 (-) |
G110208 | adamts16,LOC107757336,LOC107558631,LOC107689003,LOC107726256,LOC107657842,LOC568792 | other | upstream | 783650 | 6029208 ~ 6034777 (-) |
G110215 | NA | other | upstream | 851117 | 6096675 ~ 6099927 (-) |