foxa2 (foxa2,LOC107656870,LOC107558496)


Basic Information

Item Value
gene id foxa2
gene name foxa2,LOC107656870,LOC107558496
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056715.1
NCBI id CM032084.1
chromosome length 22256391
location 19593939 ~ 19596388 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043262259.1
TTTCAAGCTGCGCAGGTGTACAATAGGGGGGCAAATGGAGAAGTCTCACGCCTAGGTGTGAGCAGATTATTCAAATAGGGGCCGAGTGAAGCAGTAGGGATTGGAGGCTCGCCCGGGCGCACAGAGCTATATCACAGCGTTAAGAGCCAGCAGCGGGCGTCATTTCAACCGCAGTCGTCTCagatacacgcacacacacacacacacacacatgcgccaGCCCTTGACAGGAGGAGAGCACGACGACGACGACACGAGTGTATCCCGTGGTCCCCGACAACCACCTTTGGCTGCCAAAGGACACACAATACCGGCATTTCTCGTGTGGGGGAAAGCGCTTTGAAAAGTAGGAGAAACTTTTTTCCAGGATGCTCGGCGCTGTGAAAATGGAGGGACACGAACACGCAGCCGACTGGAGCACTTACTACGGAGAGCCCGAGTGTTACACCTCCGTGAGCAACATGAACACCGGACTGGGAATGAACTCCATGAACACTTACATGACCATGTCCGGGATGAGCTCGACCGCAAATATGACAGCGGCTAACACCATGAACATGTCTTACGTCAACACGGGCATGAGCCCCTCGATGACGGGCATGTCTCCCGGCACCGGGGCGATGGCCGGCATGGGCGCCGGTATGACGGGCATGAGCGCAGCCCTGAGCCCGACCATGAGCCCCATGACAGCCCAAGCGCCCTCCATGAACGCCTTAACCTCGTACAGCAATATGAACGCCATGAGCCCCATGTACGGCCAGTCGAACATAAACAGATCGAGAGACCCGAAGACCTACCGGAGGAGCTACACGCACGCCAAGCCGCCCTACTCGTACATTTCCCTAATAACCATGGCCATCCAGCAGTCGCCCAGTAAGATGCTGACCCTCAGCGAGATCTATCAGTGGATAATGGACCTTTTCCCTTTTTACCGACAGAACCAGCAGCGCTGGCAGAACTCTATCCGCCACTCGCTGTCCTTCAACGACTGCTTCCTGAAAGTGCCGCGCTCCCCGGACAAGCCGGGGAAGGGCTCGTTTTGGACCCTTCACCCCGATTCCGGAAACATGTTCGAAAACGGCTGCTATCTGAGGAGGCAAAAGCGCTTCAAGTGCGATAAGAAACTGAGCAAGGAGCCGGGCCGGAAAACCTCGGAGGGCGGCTCGAACAGCAGCTCCGAGAGCTGCAACGGGAACGAATCCCCTCACTCCAACTCGTCCGGCAACGAGCACAAAAGATCCCTTTCCGACATGAAGTCGGCTCAGGGTCTGAGCCCGGAGCACGCAGCCTCCCCGGGCTCCCAAGCGCAGCATCTCCTGGCCCAGCATCACTCGGTTTTGGCGCACGAGGGACACCTGAAGCCGGAGCATCACTATTCCTTCAACCACCCCTTCTCCATCAACAACCTCATGTCGTCGGAGCAACAGCATCACAAAATGGACCTAAAGACATACGAGCAGGTGATGCATTACGGTTACGGCTCTCCGATGGCCGGCGCGTTATCCATGGGCTCCATGGCGAGCAAAGCGGGCCTGGACTCGCCGGACACCTCGTACTATCAAGGTGTGTACTCCAGGCCCATCCTGAACTCTTCCTAAGCTCCCACGGACCCTGCGACgatttgtacatttgtaaaatgtttgtgtatatgtattctgatttttttttttttttggacgtTCCCGTTAATTTAGATGTTCGttagtaattattttgtaaaagatCTGTCGACAATGTGACGAACTCTTCGAGGCGGCTTTTGAAAAAGGACCAAAACCACACCGAAGGACTGCGGACGGATTGAAGTTCTTCAGTCACCTGTGTAAACTTATTTATGGCTTGTAAATGTGTATTCTTGTAGTCGATGACAAGAACAGAATCtatattaaagtgttatttgga

Function

symbol description
foxa2 Enables transcription cis-regulatory region binding activity. Acts upstream of or within axial mesoderm morphogenesis; endoderm development; and nervous system development. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; digestive system; endoderm; mesoderm; and swim bladder. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FOXA2 (forkhead box A2).

NR:

description
hepatocyte nuclear factor 3-beta

GO:

id name namespace
GO:0032289 central nervous system myelin formation biological_process
GO:0007492 endoderm development biological_process
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process
GO:0033504 floor plate development biological_process
GO:0048319 axial mesoderm morphogenesis biological_process
GO:0042593 glucose homeostasis biological_process
GO:0007389 pattern specification process biological_process
GO:0048665 neuron fate specification biological_process
GO:0010817 regulation of hormone levels biological_process
GO:0045666 positive regulation of neuron differentiation biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0007418 ventral midline development biological_process
GO:0051090 regulation of DNA-binding transcription factor activity biological_process
GO:0021779 oligodendrocyte cell fate commitment biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0008134 transcription factor binding molecular_function
GO:0003690 double-stranded DNA binding molecular_function
GO:0019904 protein domain specific binding molecular_function
GO:0008301 DNA binding, bending molecular_function

KEGG:

id description
K08035 FOXA2, HNF3B; forkhead box protein A2, hepatocyte nuclear factor 3-beta

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043262259.1 True 1902 mRNA 0.54 2 19593939 19596388

Neighbor

gene id symbol gene type direction distance location
nkx2.2a nkx2.2a,nkx2-2,LOC107558480,LOC107707659,LOC107737280,LOC108435751 coding downstream 124767 19465008 ~ 19469172 (-)
nkx2.4a nkx2.4a,nkx2-4,LOC107707661,LOC107688185,LOC107558479,LOC107737279 coding downstream 164430 19426713 ~ 19429509 (-)
LOC122361743 NA coding downstream 601059 18981501 ~ 18992880 (-)
LOC122362028 NA coding downstream 612572 18978706 ~ 18981367 (-)
LOC122361746 vps39,LOC107707670,LOC107572021,LOC107687842,LOC107558491,LOC107687939 coding downstream 655302 18921965 ~ 18938637 (-)
prkd3 prkd3,LOC107657158,LOC108435798,LOC108270251,LOC107736975,LOC107656871 coding upstream 12390 19608778 ~ 19654074 (-)
mocs3 mocs3,LOC107657152,LOC107737282,LOC107679656,LOC107736978 coding upstream 58057 19654445 ~ 19661295 (-)
hs1bp3 NA coding upstream 117871 19714259 ~ 19729127 (-)
arel1 arel1,LOC107573237,LOC107672354,LOC107744492,LOC107704359 coding upstream 137018 19733406 ~ 19753592 (-)
LOC122362216 gpx2,LOC107728961,LOC107680104 coding upstream 385823 19982211 ~ 19983877 (-)
G122508 NA non-coding downstream 1275 19581444 ~ 19592664 (-)
G122387 NA non-coding downstream 89108 19504031 ~ 19504831 (-)
G122384 NA non-coding downstream 97218 19485042 ~ 19496721 (-)
G122350 NA non-coding downstream 219438 19372764 ~ 19374501 (-)
G122344 NA non-coding downstream 423186 19170547 ~ 19170753 (-)
G122556 NA non-coding upstream 202334 19798722 ~ 19799398 (-)
G122566 NA non-coding upstream 222572 19818960 ~ 19819187 (-)
G122594 NA non-coding upstream 570636 20167024 ~ 20167641 (-)
G122625 NA non-coding upstream 928677 20525065 ~ 20528911 (-)
G122628 NA non-coding upstream 998918 20595306 ~ 20640412 (-)
ralgapa2 ralgapa2,LOC107687934 other downstream 311483 19147331 ~ 19282456 (-)
LOC122362226 vps39,LOC107707670,LOC107572021,LOC107687842,LOC107558491,LOC107687939,LOC107758712 other downstream 757319 18819663 ~ 18836620 (-)
G122247 NA other downstream 803059 18786882 ~ 18790880 (-)
LOC122361943 NA other downstream 948947 18631257 ~ 18644992 (-)
LOC122361613 NA other downstream 1312367 18279458 ~ 18281572 (-)
LOC122362030 cldn20,tfb1m,LOC101886267,LOC107571061,LOC107675320,LOC107573130,LOC107728965,LOC108443299,LOC108269830,LOC107680107,LOC107728964,LOC107675319 other upstream 228071 19824459 ~ 20053139 (-)
LOC122362234 kif26a,kif26ab,LOC107739214,LOC107662598,LOC107732702,LOC107559913,LOC107586892 other upstream 960335 20556723 ~ 20636159 (-)
aspg aspg,LOC107586863,LOC107739215,LOC107732472,LOC107662599 other upstream 1161328 20757716 ~ 20770229 (-)
nenf nenf,LOC107739254,LOC107664444,LOC107732830,LOC107662615,LOC107586886 other upstream 1318813 20915201 ~ 20916639 (-)
tmem63c tmem63c,LOC107732232 other upstream 1481673 21078061 ~ 21116556 (-)

Expression


Co-expression Network