nkx2.4a (nkx2.4a,nkx2-4,LOC107707661,LOC107688185,LOC107558479,LOC107737279)



Basic Information


Item Value
gene id nkx2.4a
gene name nkx2.4a,nkx2-4,LOC107707661,LOC107688185,LOC107558479,LOC107737279
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_056715.1
NCBI id CM032084.1
chromosome length 22256391
location 19426713 ~ 19429509 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence


>XM_043262466.1
GCTGAAATGTCAATGACTATTGTTTGCTGGTCTAGGGAGTCGCTCCGCCCCTCGTGTTTGTCGTAAATCTGGCGCCTGGCTACAATAAACCTGAGATAAGAGTGGCCAGGGCTCGCCTCCTTCTCCAAGGCGATCAATCGGATCTCAGGCATACTACAAGCACTCTCTTACGTCGACGTCCACGAGAACAGAGCTGATACAACAACACGGCTGAGCTCCACCACCAAATATCCATCTGCTTTTCTGAACCATGTCGCTGAGCCCAAAGCACACGACACCTTTCTCAGTGACAGATATTTTGAGCCCAATCGAGGAGACTTACAAGAAGTTTAGTGGCATGGAGAGCACCGGAAACCTCACATCTCCACTGGGAGCGTACCGGCAACCTCAGGTGTCCCAGACTGGCATGCAGCAACACTCCATGGGCCACAACGCCGCCGTGGCGACCACCTACCACATGCCACACTCCGTTTCCCAGTTCTCGCACAGTGCAATGGGGGGCTACTGCAATGGCAGCATTGCCAACATGGGGGACCTACCCTCTTACCAAGAAACTATGAGGAACAGCGCAGCGGCAACAGGGTGGTACGGCGCCAATCCTGACCCTAGATACTCAACAATTTCTAGATTCATGGGACCTTCCACAGGTATGAACATGACAGGAATGGGCACGCTGACAGGCATGGCCGACACCACCAAATCCATCCCACCTCTGCACGCAGCTCCAAGGAGGAAACGACGGGTGCTCTTCTCTCAAGCGCAAGTCTACGAGCTGGAAAGGAGATTTAAGCAACAGAAATACCTCTCGGCGCCCGAGAGGGAACACCTGGCCAGCATGATACACCTGACCCCGACGCAGGTCAAGATCTGGTTTCAGAACCATCGCTACAAGATGAAACGGCAGGCCAAGGACAAGGCAGCGCAGCAGCTTCAACAGGAGGGCAACCTGTGTCAACAGCAGCAGTCGCCGAGGAGAGTGGCCGTCCCCGTCTTAGTGAAGGACGGCAAGCCTTGTCAAAACGGCTCCAACACACCGACGCCAAACCAACAGcaaatgcagcagcagcagcagcagcagcagaacgGTTCCGGGGTCGTGCTTCCTACCTCCAGTAACTCTATGAACCAACACCAAACCCAGCAGGTCAACGCACTGGTCCAGGCCCAAGACCTGGAGGAAATGTCCCCCAGCCCGCCGTCACTCCACTCGCAAATGAACAACATGGGCCAGATGGACACTACCGTAGATTACACGAATAACATGGTCACGTCGAATCTGCTTTACGGCAGAACGTGGTAAGAACGGGCGCCTTCCCTTTCCTCGGTATTTCCACGAACTTTAGCGCGCTCTGAACGAAGAACCGCGAAAGCAGACTTCACGAGCCGAGCGCCCGCGCGGATGGAgccagtttgtttttgtttttttttttgcgggaAATTTATcacttttttctaaaaacaaaacgttttttgGTCACGGTTTTTTCTACAGCGACCCAGCTACTCCGTTAcggacaaaaataacaatttctaGCCTCGCGCTCTGTGTCTGGGACTTCCTTTCGTTTGTTCTAGTAGAAGGTTGTCTGTTGTTTAAACTAAACTGCTGCTCCACATCTATGGCAATGCCAGGACGCGGGAAGCAGTGTTTCATATTTCAGGTACGAACTTCTAGCAAGAACTGGAAAAGTTCCAGATCTCAATAAAATGCCTGAACGTGCGACGGAAGTgactattgtaaaaaaaaaaaaaaaaaatgatgataataataataataataataataataataatgtattcatttagaGAAATGAAAAGTAGGGATTGTATATTTGGCTAACACTTAAGTTTCTGTTTActtgtaatataaatgtttgagTCTTTTCGTTGGTCATTTAttctattcttgttttttttttttggtaaattaaaACGAAGACGCGAAGACGACGGCTGCTGTATGTGTTTCAAACCAATTGAACGTtaacaataaatcaattaaaccgCGCGCCATTGTTGGGGAATTAATGTGTGCAGAGTAATTTCTGTGAAGAGCGTTTTTATTCgagaaatatctaaaaatacatttattgtgaaAACCTTTCACTGATTTTAAAAGGAAGATACCTTCATTTAAATACAGACCGTTTTGATGCGTCCATGGTTAATTACTTACTTGAAATTTGTTACAAATTCGATTACCTTTCCTAAATTAAATATACCCTACACAGATGTAATAATCATAACCTTAACCCTAATCACGTGTAAGCCGTTTTAAACTCGATCAGTTTATATTAAGCGGATGATGGAACgatatttttggttatttttattttattttattttttttgattcattttatttaacgtGTCTGATATTTCAGTGGCTCGTCTGTGTGTTGATATCCAAAGAATACACATGTATACTTTACACCACGAAA
>XM_043262467.1
GCTGAAATGTCAATGACTATTGTTTGCTGGTCTAGGGAGTCGCTCCGCCCCTCGTGTTTGTCGTAAATCTGGCGCCTGGCTACAATAAACCTGAGATAAGAGTGGCCAGGGCTCGCCTCCTTCTCCAAGGCGATCAATCGGATCTCAGGCATACTACAAGCACTCTCTTACGTCGACGTCCACGAGAACAGAGCTGATACAACAACACGGCTGAGCTCCACCACCAAATATCCATCTGCTTTTCTGAACCATGTCGCTGAGCCCAAAGCACACGACACCTTTCTCAGTGACAGATATTTTGAGCCCAATCGAGGAGACTTACAAGAAGTTTAGTGGCATGGAGAGCACCGGAAACCTCACATCTCCACTGGGAGCGTACCGGCAACCTCAGGTGTCCCAGACTGGCATGCAGCAACACTCCATGGGCCACAACGCCGCCGTGGCGACCACCTACCACATGCCACACTCCGTTTCCCAGTTCTCGCACAGTGCAATGGGGGGCTACTGCAATGGCAGCATTGCCAACATGGGGGACCTACCCTCTTACCAAGAAACTATGAGGAACAGCGCAGCGGCAACAGGGTGGTACGGCGCCAATCCTGACCCTAGATACTCAACAAGTATGAACATGACAGGAATGGGCACGCTGACAGGCATGGCCGACACCACCAAATCCATCCCACCTCTGCACGCAGCTCCAAGGAGGAAACGACGGGTGCTCTTCTCTCAAGCGCAAGTCTACGAGCTGGAAAGGAGATTTAAGCAACAGAAATACCTCTCGGCGCCCGAGAGGGAACACCTGGCCAGCATGATACACCTGACCCCGACGCAGGTCAAGATCTGGTTTCAGAACCATCGCTACAAGATGAAACGGCAGGCCAAGGACAAGGCAGCGCAGCAGCTTCAACAGGAGGGCAACCTGTGTCAACAGCAGCAGTCGCCGAGGAGAGTGGCCGTCCCCGTCTTAGTGAAGGACGGCAAGCCTTGTCAAAACGGCTCCAACACACCGACGCCAAACCAACAGcaaatgcagcagcagcagcagcagcagcagaacgGTTCCGGGGTCGTGCTTCCTACCTCCAGTAACTCTATGAACCAACACCAAACCCAGCAGGTCAACGCACTGGTCCAGGCCCAAGACCTGGAGGAAATGTCCCCCAGCCCGCCGTCACTCCACTCGCAAATGAACAACATGGGCCAGATGGACACTACCGTAGATTACACGAATAACATGGTCACGTCGAATCTGCTTTACGGCAGAACGTGGTAAGAACGGGCGCCTTCCCTTTCCTCGGTATTTCCACGAACTTTAGCGCGCTCTGAACGAAGAACCGCGAAAGCAGACTTCACGAGCCGAGCGCCCGCGCGGATGGAgccagtttgtttttgtttttttttttgcgggaAATTTATcacttttttctaaaaacaaaacgttttttgGTCACGGTTTTTTCTACAGCGACCCAGCTACTCCGTTAcggacaaaaataacaatttctaGCCTCGCGCTCTGTGTCTGGGACTTCCTTTCGTTTGTTCTAGTAGAAGGTTGTCTGTTGTTTAAACTAAACTGCTGCTCCACATCTATGGCAATGCCAGGACGCGGGAAGCAGTGTTTCATATTTCAGGTACGAACTTCTAGCAAGAACTGGAAAAGTTCCAGATCTCAATAAAATGCCTGAACGTGCGACGGAAGTgactattgtaaaaaaaaaaaaaaaaaatgatgataataataataataataataataataataatgtattcatttagaGAAATGAAAAGTAGGGATTGTATATTTGGCTAACACTTAAGTTTCTGTTTActtgtaatataaatgtttgagTCTTTTCGTTGGTCATTTAttctattcttgttttttttttttggtaaattaaaACGAAGACGCGAAGACGACGGCTGCTGTATGTGTTTCAAACCAATTGAACGTtaacaataaatcaattaaaccgCGCGCCATTGTTGGGGAATTAATGTGTGCAGAGTAATTTCTGTGAAGAGCGTTTTTATTCgagaaatatctaaaaatacatttattgtgaaAACCTTTCACTGATTTTAAAAGGAAGATACCTTCATTTAAATACAGACCGTTTTGATGCGTCCATGGTTAATTACTTACTTGAAATTTGTTACAAATTCGATTACCTTTCCTAAATTAAATATACCCTACACAGATGTAATAATCATAACCTTAACCCTAATCACGTGTAAGCCGTTTTAAACTCGATCAGTTTATATTAAGCGGATGATGGAACgatatttttggttatttttattttattttattttttttgattcattttatttaacgtGTCTGATATTTCAGTGGCTCGTCTGTGTGTTGATATCCAAAGAATACACATGTATACTTTACACCACGAAA

Function


symbol description
nkx2.4a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within hypothalamus development. Predicted to be active in nucleus. Is expressed in caudal tuberculum; diencephalon; forebrain; hypothalamus; and intermediate hypothalamus. Orthologous to human NKX2-4 (NK2 homeobox 4).
nkx2-4 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus.

NR:

description
homeobox protein Nkx-2.4-like isoform X2

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K09344 NKX2-4; homeobox protein Nkx-2.4

RNA


RNA id representative length rna type GC content exon number start site end site
XM_043262466.1 True 2440 mRNA 0.46 2 19426713 19429509
XM_043262467.1 False 2413 mRNA 0.46 2 19426713 19429509

Neighbor


gene id symbol gene type direction distance location
LOC122361743 NA coding downstream 433833 18981501 ~ 18992880 (-)
LOC122362028 NA coding downstream 445346 18978706 ~ 18981367 (-)
LOC122361746 vps39,LOC107707670,LOC107572021,LOC107687842,LOC107558491,LOC107687939 coding downstream 488076 18921965 ~ 18938637 (-)
LOC122361744 galnt16,LOC107707671,LOC107687852 coding downstream 509223 18887551 ~ 18917490 (-)
LOC122362022 NA coding downstream 562271 18860972 ~ 18864442 (-)
nkx2.2a nkx2.2a,nkx2-2,LOC107558480,LOC107707659,LOC107737280,LOC108435751 coding upstream 35499 19465008 ~ 19469172 (-)
foxa2 foxa2,LOC107656870,LOC107558496 coding upstream 164430 19593939 ~ 19596388 (-)
prkd3 prkd3,LOC107657158,LOC108435798,LOC108270251,LOC107736975,LOC107656871 coding upstream 179269 19608778 ~ 19654074 (-)
mocs3 mocs3,LOC107657152,LOC107737282,LOC107679656,LOC107736978 coding upstream 224936 19654445 ~ 19661295 (-)
hs1bp3 NA coding upstream 284750 19714259 ~ 19729127 (-)
G122350 NA non-coding downstream 52212 19372764 ~ 19374501 (-)
G122344 NA non-coding downstream 255960 19170547 ~ 19170753 (-)
G122343 insm1,insm1b,LOC107558475,LOC107564444,LOC107756196 non-coding downstream 257224 19167381 ~ 19169489 (-)
G122334 NA non-coding downstream 287887 19138526 ~ 19138826 (-)
G122274 NA non-coding downstream 359745 19026780 ~ 19066968 (-)
G122384 NA non-coding upstream 55533 19485042 ~ 19496721 (-)
G122387 NA non-coding upstream 74522 19504031 ~ 19504831 (-)
G122508 NA non-coding upstream 151935 19581444 ~ 19592664 (-)
G122556 NA non-coding upstream 369213 19798722 ~ 19799398 (-)
G122566 NA non-coding upstream 389451 19818960 ~ 19819187 (-)
ralgapa2 ralgapa2,LOC107687934 other downstream 144257 19147331 ~ 19282456 (-)
LOC122362226 vps39,LOC107707670,LOC107572021,LOC107687842,LOC107558491,LOC107687939,LOC107758712 other downstream 590093 18819663 ~ 18836620 (-)
G122247 NA other downstream 635833 18786882 ~ 18790880 (-)
LOC122361943 NA other downstream 781721 18631257 ~ 18644992 (-)
LOC122361613 NA other downstream 1145141 18279458 ~ 18281572 (-)
LOC122362030 cldn20,tfb1m,LOC101886267,LOC107571061,LOC107675320,LOC107573130,LOC107728965,LOC108443299,LOC108269830,LOC107680107,LOC107728964,LOC107675319 other upstream 394950 19824459 ~ 20053139 (-)
LOC122362234 kif26a,kif26ab,LOC107739214,LOC107662598,LOC107732702,LOC107559913,LOC107586892 other upstream 1127214 20556723 ~ 20636159 (-)
aspg aspg,LOC107586863,LOC107739215,LOC107732472,LOC107662599 other upstream 1328207 20757716 ~ 20770229 (-)
nenf nenf,LOC107739254,LOC107664444,LOC107732830,LOC107662615,LOC107586886 other upstream 1485692 20915201 ~ 20916639 (-)
tmem63c tmem63c,LOC107732232 other upstream 1648552 21078061 ~ 21116556 (-)

Expression



Co-expression Network