CI01000001_01999489_02002753 (IGFBP6B, IGFBP6)


Basic Information

Item Value
gene id CI01000001_01999489_02002753
gene name IGFBP6B, IGFBP6
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000001
NCBI id null
chromosome length 13537560
location 1998128 ~ 2002928 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000001_01999489_02002753.mRNA
TCGTTCTTGGTTTGTATCCTCTGGCACTGCAGGGGACTCCCGGCTCGCAGCCTCACCAAGCAAAGCTGAAGAGCGAGCAAAGAAACAGAGAGGGGAAAAAGAAACAGACTTCCAGAAATAGCATCAGCCACGTACGACAGAACCGATCATGGAGAACCTGAGACCCAGACGCAAGATGTCTTTCCTTTCCAACTTGACACCCGTTGTCCTGTTGCTGATCGTCCACTGTGGATCCTGGTCTCTGGCGGGTCGTTTGGGCCCCCACAAAAACTGCCTGACCTGCAAAGACGGGCAGTCCTCGGGCGCGGGCCGGGCCTCCAGGGACCCGGCCGGGGCGGCCAGCATGACCATGTTGGCATTGGGGGAGCCCTGTGGGGTGTACACCCTGAGCTGTGCCAAGGGGCTTCGCTGTGTGCCCCCTCCGCGTGAACACAGCCCCCTTCAGGCTCTGCTGCAGGGCAGAGGCTTCTGCGCCAAACAGAGCAAGACGAGTCCCACCGAGAAGCCCCGCCCCACAGGGGCACATCCTTCACACAGTGGTGAAATAGAAAAGGCTCCATGTCGTAAGCTGCTCAACACTGTCTTGCGAGGTCTCGAGCTCACCATTTTCCAGTCTGATCGCGACATCTACATCCCGAACTGTGACACGCGTGGGTTCTACAGGAAAAAGCAGTGTCGGTCCTCTAAGGGCATGCAGCGCGGCAACTGCTGGTGCGTCGACGAGATGGGCACCACCGTGCCGCCACGTGCCGGGGAGGATGGTACTTTACCATGTGATGGAGAGTGAGGGGAGCGACGGCCCCACAGCTCTGAGCCTGGAGGAAGAGGAGGGGTACAGGGAGAGGGGATGACTTCAGCTCGGTGCAAGACACTGCCTGACCAGGACACACCAGGGATAAACCACTTCACATGGGATCGGGCCCTCACTCAGAACGTCCAGAGCACGTTCACTGCCATAAACTCGACCATCATGAACAGACAGCATCAGAACACAGAAATAATGACCACTACACCACATGAGCTTAAGTCGAGATAGGTCAGCTGTTAGAGAAATCTTTAATTCCTTGCCCTACAATACAACTTCTTGTACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGAGAGATAGCTATCCACACCTATGTTTGTTTCTCAATGGGCTGTTATACTGTTAAAACCGTCCCCTCTCCCCTTCTCCAATGAAACACTGACTAAACTATACTTAAGAAAACGGAATTTACCTTCTCGTCTAATTTATTCTGGAGCATTACTAAATTTCCTTGAATACTTTCCTCGAGGACTTGTACACATTGTCATGTAATCGACATCTAAACTCTATCATAATGTGCACATTCGGAAAGTACTCCTTTTTCGTTCATACGACACCCTGACTACAAACACGCGTCGTGGATTATTTGTACATAAGTGAGGTTATTGTGGTTGGTTGTGTCATGAGGTGGAATATTCTTGAATGCTGATGGCTGTTACCTTTTCTGAGAAGTTGTTAGGCATATTTTTATATATTTCAATTTGCTATTTTATATATATATATATATATAAATATATGAATATAAATATATATAAATTGTTGATTTATTTAATGAACTACGATGCCATGTATTTTTATATTGTCAGCAGTTTTTCATTGTCAAAACAGAGCTTATTTTATTCACTAAGTGAGTGAGTGCCATACGTTGGTGACCCCATACAAAGGGATTAAAAACAAAAACACAATTTAAACACCCTTTAGAGAGCATTTACTGCTGTACATGTGTGTTTTTTTATATTATTATTATTATTATTATTATTTCATGTCACATTTGTTTCATTATTTATGTTGATCCTTCAGTATTGGAAAGTGTTACTATATCGCTTAATTTTCAATATTTCAGATTGTATGCTGGGTATTTTGTTCAGAACTCTGTGTTTTCTCATTCCCACAATGCATTGAGGAAAAAAAAGTGCACAAAATAATGTCTGAGCAATGTACCTCACAATGATTTTGTTGTATCGATATATGTGCCAGTAGTTGTGGGCCCTTAAAGGAACCCATTGCAAAAAAAAAATATAAGGTGTGCAAGAACTATGATACAAAAAAAAAAAAAAAACAGATACAGAGAAAAATAAA

Function

symbol description
igfbp6b Predicted to enable fibronectin binding activity; insulin-like growth factor I binding activity; and insulin-like growth factor II binding activity. Predicted to be involved in regulation of insulin-like growth factor receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in obesity. Orthologous to human IGFBP6 (insulin like growth factor binding protein 6).
igfbp6 Enables identical protein binding activity and insulin-like growth factor II binding activity. Involved in cell migration and positive regulation of stress-activated MAPK cascade. Part of insulin-like growth factor binary complex. Implicated in obesity. Biomarker of breast cancer; in situ carcinoma; leiomyoma; and neovascular inflammatory vitreoretinopathy.

GO:

id name namespace
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway biological_process

KEGG: NA

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000001_01999489_02002753.mRNA True 2148 mRNA 0.45 4 1998128 2002928

Neighbor

gene id symbol gene type direction distance location
CI01000001_01976950_01992032 GPR182, PIP4K2CA, PIP4K2C coding downstream 4567 1976716 ~ 1993561 (-)
CI01000001_01932927_01933914 TSPAN31 coding downstream 64214 1932621 ~ 1933914 (-)
CI01000001_01902970_01917410 MARCH9 coding downstream 80674 1902429 ~ 1917454 (-)
CI01000001_01873684_01874535 NA coding downstream 123593 1873640 ~ 1874535 (-)
CI01000001_01772744_01773670 NA coding downstream 224458 1772331 ~ 1773670 (-)
CI01000001_02057429_02071506 LIMA1A coding upstream 53886 2056814 ~ 2071506 (-)
CI01000001_02126257_02127537 NA coding upstream 122137 2125065 ~ 2127567 (-)
CI01000001_02141590_02142836 COPZ1, COPZ1.L, COPZ1-B coding upstream 138632 2141560 ~ 2142986 (-)
CI01000001_02159372_02162554 HNRNPA1, ROA1 coding upstream 156231 2159159 ~ 2162554 (-)
CI01000001_02173311_02179118 NA coding upstream 169842 2172770 ~ 2180987 (-)
G14267 NA non-coding downstream 22261 1975195 ~ 1975867 (-)
G14261 NA non-coding downstream 75888 1921899 ~ 1922240 (-)
G14259 NA non-coding downstream 77282 1920595 ~ 1920846 (-)
G14257 NA non-coding downstream 102038 1893706 ~ 1896090 (-)
G14112 NA non-coding downstream 126562 1867635 ~ 1871566 (-)
G14217 NA non-coding upstream 1233 2004161 ~ 2005063 (-)
G14213 NA non-coding upstream 2367 2005295 ~ 2007049 (-)
G14216 NA non-coding upstream 99228 2102156 ~ 2102501 (-)
G14198 NA non-coding upstream 99661 2102589 ~ 2103469 (-)
G14293 NA non-coding upstream 115427 2118355 ~ 2118566 (-)
G14219 NA other downstream 3230 1994210 ~ 1994898 (-)
G14104 NA other downstream 230670 1763669 ~ 1771468 (-)
CI01000001_00362143_00378213 NA other downstream 1600995 361614 ~ 378213 (-)
CI01000001_00238241_00249437 NA other downstream 1740611 238241 ~ 249437 (-)
CI01000001_00124107_00131285 ELOVL4B other downstream 1863203 122814 ~ 131380 (-)
G14228 NA other upstream 53046 2055974 ~ 2056478 (-)
CI01000001_02258523_02262621 NA other upstream 256461 2258442 ~ 2263103 (-)
CI01000001_04395469_04399381 FKBP1B.L, FKBP1B, FKBP1AA, FKBP1AB, FKBP1A, FKB1B, FKB1A other upstream 2389386 4392314 ~ 4399804 (-)
CI01000001_04468566_04523431 DNMT3BB.1 other upstream 2473356 4468209 ~ 4523431 (-)
CI01000001_04726550_04727511 PDPFB, PPDPFB, PPDPF other upstream 2566154 4725927 ~ 4728210 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_021879 igfbp6b coding NC_007134.7 CM002907.2 36601984 ~ 36605837 (+)