grhl2b (grhl2b,grhl2,LOC107738316,LOC107672862,LOC107748368,LOC107698657,LOC107552317,LOC107550099)


Basic Information

Item Value
gene id grhl2b
gene name grhl2b,grhl2,LOC107738316,LOC107672862,LOC107748368,LOC107698657,LOC107552317,LOC107550099
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056717.1
NCBI id CM032086.1
chromosome length 20532727
location 4432143 ~ 4450461 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043217825.1
CCAAATACTTTACACCGAAAAAAAGCCGTCAAAGTTTACCTATAGGTCTATACgcagacaataaaaataataaaagtaggTTTAACACgctctaaatgtttttttgctaatGCACAGGTTGTGTTTTGATTGATAAATCACAGGTTGAAATCATCGGGAAGGACGGGACGGGGGTGCTCAGGTGTTTCCTACCTGCTCCTTCAGCCCTTGAGAAATAAGCGGAGAGGGAAAAGTCGATTTACCTGTAGCCCAGGTTCTGGCATCTCTCACTCGCGCGCTGTCTTCTGTTACCTGCACCGACTTGAAAGTCCAGTTTCACAAGGAAGAACCGCGGAGGAAGAGAAATATGTCACAGGAGGCAGACAGcaagAGGCTGGTTGTCGTGGTGCCCAATGAGCCGTCCTTCCACCCGCGCCGGGACTACACCAGTGAGGACGAGGCCTGGAGGTCTTACCTGGAGAATCCTCTGACGGCGGCCACGAAGGCCATGATGAGCATCAATGGAGACGAAGACAGCGCTGCCGCCCTGGGGCTCCTCTATGAGTACTACAAGGTGCCCAGAGATAAGAGAGTTTTGCCCATCAGTAAAGTGGTTGAAGTTTCAGAGGAGCCAGAAAAGAGAAACGCTCCAGTGGGAAGCAGCAGTCAGATGGAGCCGGAGGCAGTGGACAACCGCGTGCAGGTCCTCAAATCAGTGCCTGTTAACCTGTCGCTCAACACGGATCACCAGGACACCAAACGGGAGCAGTACGGCGTGTCTGCGGGAGAGAGCGGGAGCGCTGCGGTGGTGAAGGCCGAGCTCTTCTCGCCTGTCTTCATGGCTTCGGGGGTTCACTACAGGAGCGAGGGAGAGGAGCCCATGCGGGTCATCTGTGAACAGACCCACTCGTTCGACGCCTCGGCCGTGTGCCACAGCGCCTACGGGAAGGACGACCATCGGAGCAGCCCGGATAGCACCTACGAGGAAGACAGCAGTGAAAAGTATCGGCCGTCGTCGCTTGGAGCTGATGACTTCATATTTGACCAGTCGGAGATGTTAGACACCTTCCAGTACACCCTCGAGGCCAGCAGGTCGTTGCGGCAGAAGCAGGGAGAAGGGCCTATGACCTACCTGAACAAAGGCCAGTTCTATGCTATCACACTGAACGAGACAAGCGCCAATAAACGCCTCCGACATCCCATCAGCAAAGTGAGGAGCGTCATCATGGTTGTATTCAGTGAAGATAAGAACCGAGATGAGCAGCTCAAGTACTGGAAGTATTGGCACTCTCGCCAGCACACGGCAAAGCAGAGGGTCCTGGACATCGCTGACTACAAAGAGAGCTTCAACACAATTGGGAATATTGAAGAAATCGCTTACAATGCCGTGTCCTTTACCTGGGACGTGAACGAGGAGGCCAAGATCTTCATCACGGTGAACTGTCTGAGCACAGACTTCTCCTCTCAGAAGGGGGTGAAGGGCCTTCCTCTGATGATTCAGATCGACACCTACAGCTACAACAACCGCAGCAACAAACCCCTCCACAGAGCCTACTGTCAGATCAAGGTCTTCTGTGATAAGGGAGCAGAGAGGAAGATCAGAGACGAGGAGAGGAAACAGAACCGCAAACAGAAGACAAAAGGAAAGGATGGAGGCGCCGGGGCGGCTTCTGTGCCGAAAAAATGCGACGCTACCTTCTTCAAAACGATGACTGATTTGGATGCCCAGCCGGTTCTCTTCATCCCGGATGTGCACTTTGGGAACTTACAGAGAGCAGGCCAGGTGTTTGCCTTCAACACAGAGGAAATCGAACGCGAAGGGAGTGTGCTGGTGAAGAGGATGTTCAGGCCGTCTGAGGACGACTTCTGTCCGCCGCCCCATAAACAGCTCAGAGAGGACACACAGAAGAGAGTGCTCCTGTACGTGAGGAAGGAGTCGGACGAGGTGTTTGACGCTCTGATGCTGCGGATGCCCACTCTCAGAGGACTCATGGATGCTATTTCAGAGAAGTACGGCGTTCCTGTTGACAGAATGGCCAAGATTTACAAGAAGAGCAAGAAGGGGATCCTGGTGAACATGGACGACAATATCATCGAGCACTATTCCAACGAGGACACGTTTATCCTGAGTATCGAGAACTACGCAGAGGCATGCAAAATCACATTAACGGAAATATGAACACCATCGCATTCAGTATGTTTAAGCTAAAAGACTTGTTACTTGGACTCCAGCCTAGTCAGATTCAACATCAGCTGTCCGTAAAATTGAATTGACATCAGCTAGAGCTGACATACCTCATTTCTCAGAGACCTTAAGTATGAGTTTTAACGGTCAATGGGACTTTCGCTGTATCCCAAACATGATGGAAAAACTTTTGCTATCACCGGCTTCACTTCAGAGTACAGACTAATTCACATTTGACTTCGTTTTGGAGACCACCGTCAGATTCCTGCCTAAAATTTCAACTGTTTCATCCAAAGGATTTCACTGGAGCGGAAGGAGATTTCTTCATCATATCAAATttctgtatgtacagtatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatactcaaaatATGAATTGGGGACTTTTCTGTGGAGTTTAAGACTGATCTGTGAAAAGCGTCCTATACTGTCaatgttctttttgtgtgtgtgtattacgttgccattaatattattgttaatgttagcTTGGTAGATATGATTCAGCTTCTTACTCACTTTTTCTGATGCAAAAAGAAAGCTATTTTTATGAGACTGTGCCATTTCAAGTTTTTGGTATGTTTAATAGAGCAAAGCAGGAGACGtgtataaatactgtaatgttgAACTGTACAGTAGCGATGATCAGAAAACGTATCAGATGAGGAAGACGCAGGAAGTGTAGCTCGGACACATTTCAGTTGCATGTTTTACATGTTGCACTCATGTCTTAATGTGAAAtgaatttttataaaagttCCATTGGTCttaaatgcaaaagatttcGTGACCTTTCGGAGCCAAACCTTTTTTCACCTTTTGCGCCAAAATATGAGTGTCACGgtttttaatcgttttttttttaaataaactacgCAGTCTGGTTCATCTCCAGGGTTCGTGCAGAACATTAACTGTGTAGCGCAGATTCGGTTGATCGGCACCATTTTgttaatgtattgtttaaaaaaacaccgTCTTTCGGaagaaataatgtaaaagggcacttcagaaataataatttgtatgtaaataaatgcatttttatcaaga

Function

symbol description
grhl2b Enables transcription cis-regulatory region binding activity. Acts upstream of or within apoptotic process involved in morphogenesis; inner ear development; and midbrain-hindbrain boundary morphogenesis. Predicted to be active in nucleus. Is expressed in several structures, including anterior axial hypoblast; midbrain hindbrain boundary neural rod; neurogenic placode; optic vesicle; and posterior lateral line system. Used to study autosomal dominant nonsyndromic deafness. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 28 and posterior polymorphous corneal dystrophy 4. Orthologous to human GRHL2 (grainyhead like transcription factor 2).
grhl2 Enables DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin DNA binding activity; and sequence-specific DNA binding activity. Involved in several processes, including bicellular tight junction assembly; negative regulation of keratinocyte differentiation; and regulation of nucleobase-containing compound metabolic process. Located in cell-cell junction and nucleoplasm. Implicated in autosomal dominant nonsyndromic deafness 28 and posterior polymorphous corneal dystrophy 4.

NR:

description
grainyhead-like protein 2 homolog

GO:

id name namespace
GO:0021555 midbrain-hindbrain boundary morphogenesis biological_process
GO:0048839 inner ear development biological_process
GO:0060561 apoptotic process involved in morphogenesis biological_process

KEGG:

id description
K09275 TFCP2; transcription factor CP2 and related proteins

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043217825.1 True 3276 mRNA 0.46 16 4432143 4450461

Neighbor

gene id symbol gene type direction distance location
psmg2 psmg2,LOC107738327,LOC107748372,LOC107672829,LOC107550101 coding downstream 21209 4408733 ~ 4410934 (-)
seh1l seh1l,LOC107668717,LOC107746927,LOC107748371,LOC107666589 coding downstream 44528 4378514 ~ 4387615 (-)
ldlrad4a ldlrad4a,LOC107668709,LOC107675658,LOC107566561,LOC107746928 coding downstream 55783 4303415 ~ 4376360 (-)
rnmt rnmt,LOC107668718,LOC107754922,LOC107566559 coding downstream 135386 4285292 ~ 4296757 (-)
mc5ra mc5ra,LOC107746932,LOC107552309,LOC107675655,LOC107754914,LOC107566557 coding downstream 165005 4244693 ~ 4267138 (-)
spag1a spag1a,LOC107738319,LOC107672845,LOC107748364,LOC107698654,LOC107550092 coding upstream 79063 4529524 ~ 4537983 (-)
adck5 adck5 coding upstream 122987 4573448 ~ 4580921 (-)
LOC122323748 pqlc1,LOC107698648,LOC107672885 coding upstream 256861 4707322 ~ 4735660 (-)
LOC122323359 si:dkey-222b8.4,LOC107672841,LOC107698638,LOC107563916,LOC107745050 coding upstream 358653 4809114 ~ 4820027 (-)
LOC122323699 chtopa,chtop,LOC107672843,LOC107563917,LOC107698644 coding upstream 371276 4821737 ~ 4827915 (-)
G130494 NA non-coding downstream 23749 4408194 ~ 4408394 (-)
LOC122323668 NA non-coding downstream 26243 4404017 ~ 4405900 (-)
G130465 NA non-coding downstream 131817 4298509 ~ 4300326 (-)
G130463 NA non-coding downstream 144273 4287488 ~ 4287870 (-)
G130459 NA non-coding downstream 164719 4267179 ~ 4267424 (-)
G130482 NA non-coding upstream 19298 4469759 ~ 4484396 (-)
G130476 pabpc1b,LOC107698655,LOC107748365,LOC107550093,LOC107738317 non-coding upstream 39799 4490260 ~ 4491487 (-)
G130690 NA non-coding upstream 288344 4738805 ~ 4744555 (-)
G130702 NA non-coding upstream 322359 4772820 ~ 4903960 (-)
G130708 NA non-coding upstream 341389 4791850 ~ 4922621 (-)
tmem222b tmem222b,LOC105903612,LOC107550652,LOC107754919,LOC107567586,LOC107700749 other downstream 880318 3537441 ~ 3551825 (-)
kdf1b LOC107700730,LOC107712602,LOC107550653,LOC107754920,LOC107567594,LOC107689538 other downstream 917464 3508834 ~ 3514679 (-)
zdhhc18b zdhhc18b,LOC107700701,LOC107737765,LOC107689541,LOC108413341,LOC107550656,LOC107570996 other downstream 1052216 3363481 ~ 3379927 (-)
LOC122323345 fam46bb,LOC107712594,LOC107700817,LOC107737782,LOC108413340,LOC103370123 other downstream 1108315 3313389 ~ 3323828 (-)
G130083 LOC103461248,LOC102786159 other downstream 1282354 3149154 ~ 3149789 (-)
polr2k NA other upstream 89518 4539979 ~ 4541629 (-)
G130696 NA other upstream 293111 4743572 ~ 4941832 (-)
LOC122323502 s100v2,LOC107672873,LOC107598219,LOC107748347,LOC107676101,LOC107550199 other upstream 636783 5087244 ~ 5222883 (-)
G130744 sema4ab,LOC107702572,LOC107672813,LOC107598230,LOC107731578,LOC107705066 other upstream 691044 5141505 ~ 5260164 (-)
G130763 NA other upstream 794892 5245353 ~ 5252189 (-)

Expression


Co-expression Network